| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuang Liang, Renbin Huang, Xing Lin, Jianchun Huang, Zhongshi Huang, Huagang Li. Effects of Yulangsan polysaccharide on monoamine neurotransmitters, adenylate cyclase activity and brain-derived neurotrophic factor expression in a mouse model of depression induced by unpredictable chronic mild stress. Neural regeneration research. vol 7. issue 3. 2015-03-13. PMID:25767498. |
our results indicate that ylsps inhibits depression by upregulating monoamine neurotransmitters, prefrontal cortex adenylate cyclase activity and hippocampal brain-derived neurotrophic factor expression. |
2015-03-13 |
2023-08-13 |
mouse |
| Jeremy C Borniger, Zachary D McHenry, Bachir A Abi Salloum, Randy J Nelso. Exposure to dim light at night during early development increases adult anxiety-like responses. Physiology & behavior. vol 133. 2015-02-19. PMID:24857721. |
mrna expression of brain derived neurotrophic factor (bdnf), a neurotrophin previously linked to early life environment and adult phenotype, was not altered in the prefrontal cortex or hippocampus by early life lan exposure. |
2015-02-19 |
2023-08-13 |
mouse |
| Idoia Marqués-Iturria, Maite Garolera, Roser Pueyo, Bàrbara Segura, Imma Hernan, Isabel García-García, Consuelo Sánchez-Garre, María Vernet-Vernet, María José Sender-Palacios, Ana Narberhaus, Mar Ariza, Carme Junqué, María Ángeles Jurad. The interaction effect between BDNF val66met polymorphism and obesity on executive functions and frontal structure. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 165B. issue 3. 2014-12-22. PMID:24619555. |
the brain derived neurotrophic factor val66met polymorphism, involved in eating behavior, has also been associated with executive functions and prefrontal cortex volume, but to date it has not been studied in relation to obesity. |
2014-12-22 |
2023-08-12 |
human |
| Natalia V Malkova, Joseph J Gallagher, Collin Z Yu, Russell E Jacobs, Paul H Patterso. Manganese-enhanced magnetic resonance imaging reveals increased DOI-induced brain activity in a mouse model of schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 24. 2014-09-12. PMID:24889602. |
additionally, compared with controls, mia offspring demonstrate higher doi-induced expression of early growth response protein 1, cyclooxygenase-2, and brain-derived neurotrophic factor in the pfc. |
2014-09-12 |
2023-08-13 |
mouse |
| Silvia Hoirisch-Clapauch, Antonio E Nard. Multiple roles of tissue plasminogen activator in schizophrenia pathophysiology. Seminars in thrombosis and hemostasis. vol 39. issue 8. 2014-06-02. PMID:24108470. |
several biochemical abnormalities seen in schizophrenics are related to decreased levels or impaired activity of tpa, including deficient dopamine transmission at d1 receptors in the prefrontal cortex, impaired cleavage of a precursor of brain-derived neurotrophic factor into its mature form (mature brain-derived neurotrophic factor), abnormal n-methyl-d-aspartate receptor-mediated signaling, reduced akt phosphorylation, and abnormal activation of reelin. |
2014-06-02 |
2023-08-12 |
Not clear |
| Alessia Luoni, Sjoerd Hulsken, Greta Cazzaniga, Giorgio Racagni, Judith R Homberg, Marco A Riv. Behavioural and neuroplastic properties of chronic lurasidone treatment in serotonin transporter knockout rats. The international journal of neuropsychopharmacology. vol 16. issue 6. 2014-01-15. PMID:23164505. |
moreover, at molecular level, lurasidone was able to normalize the reduced expression of the neurotrophin brain-derived neurotrophic factor in the prefrontal cortex of sert ko rats, an effect that occurred through the regulation of specific neurotrophin transcripts (primarily exon vi). |
2014-01-15 |
2023-08-12 |
rat |
| Shuichi Chiba, Tadahiro Numakawa, Midori Ninomiya, Misty C Richards, Chisato Wakabayashi, Hiroshi Kunug. Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex. Progress in neuro-psychopharmacology & biological psychiatry. vol 39. issue 1. 2013-01-21. PMID:22664354. |
chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex. |
2013-01-21 |
2023-08-12 |
human |
| Wei-Sheng Wang, Shuo Kang, Wen-Tao Liu, Mu Li, Yao Liu, Chuan Yu, Jie Chen, Zhi-Qiang Chi, Ling He, Jing-Gen Li. Extinction of aversive memories associated with morphine withdrawal requires ERK-mediated epigenetic regulation of brain-derived neurotrophic factor transcription in the rat ventromedial prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 40. 2013-01-17. PMID:23035088. |
extinction of aversive memories associated with morphine withdrawal requires erk-mediated epigenetic regulation of brain-derived neurotrophic factor transcription in the rat ventromedial prefrontal cortex. |
2013-01-17 |
2023-08-12 |
rat |
| Rong-Jian Liu, Francis S Lee, Xiao-Yuan Li, Francis Bambico, Ronald S Duman, George K Aghajania. Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex. Biological psychiatry. vol 71. issue 11. 2012-10-04. PMID:22036038. |
brain-derived neurotrophic factor val66met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex. |
2012-10-04 |
2023-08-12 |
mouse |
| Clement Hamani, Danilo C Machado, Débora C Hipólide, Francisco P Dubiela, Deborah Suchecki, Carlos E Macedo, Fabio Tescarollo, Uilton Martins, Luciene Covolan, José N Nobreg. Deep brain stimulation reverses anhedonic-like behavior in a chronic model of depression: role of serotonin and brain derived neurotrophic factor. Biological psychiatry. vol 71. issue 1. 2012-03-30. PMID:22000731. |
we have studied the effects of ventromedial prefrontal cortex (vmpfc) stimulation in a chronic model of depression and assessed the involvement of the serotonergic system and brain derived neurotrophic factor (bdnf) in a dbs response. |
2012-03-30 |
2023-08-12 |
Not clear |
| B Ray, D L Gaskins, T J Sajdyk, J P Spence, S D Fitz, A Shekhar, D K Lahir. Restraint stress and repeated corticotrophin-releasing factor receptor activation in the amygdala both increase amyloid-β precursor protein and amyloid-β peptide but have divergent effects on brain-derived neurotrophic factor and pre-synaptic proteins in the prefrontal cortex of rats. Neuroscience. vol 184. 2011-09-13. PMID:21477639. |
restraint stress and repeated corticotrophin-releasing factor receptor activation in the amygdala both increase amyloid-β precursor protein and amyloid-β peptide but have divergent effects on brain-derived neurotrophic factor and pre-synaptic proteins in the prefrontal cortex of rats. |
2011-09-13 |
2023-08-12 |
rat |
| Emilene B S Scherer, Maira J da Cunha, Cristiane Matté, Felipe Schmitz, Carlos A Netto, Angela T S Wys. Methylphenidate affects memory, brain-derived neurotrophic factor immunocontent and brain acetylcholinesterase activity in the rat. Neurobiology of learning and memory. vol 94. issue 2. 2010-12-13. PMID:20561592. |
the present study investigated the effects of chronic administration of methylphenidate to juvenile rats on spatial memory, brain-derived neurotrophic factor immunocontent and acetylcholinesterase activity in hippocampus and prefrontal cortex. |
2010-12-13 |
2023-08-12 |
rat |
| Emilene B S Scherer, Maira J da Cunha, Cristiane Matté, Felipe Schmitz, Carlos A Netto, Angela T S Wys. Methylphenidate affects memory, brain-derived neurotrophic factor immunocontent and brain acetylcholinesterase activity in the rat. Neurobiology of learning and memory. vol 94. issue 2. 2010-12-13. PMID:20561592. |
after that, animals were sacrificed and hippocampus and prefrontal cortex were dissected out for determination of brain-derived neurotrophic factor immunocontent and acetylcholinesterase activity. |
2010-12-13 |
2023-08-12 |
rat |
| Emilene B S Scherer, Maira J da Cunha, Cristiane Matté, Felipe Schmitz, Carlos A Netto, Angela T S Wys. Methylphenidate affects memory, brain-derived neurotrophic factor immunocontent and brain acetylcholinesterase activity in the rat. Neurobiology of learning and memory. vol 94. issue 2. 2010-12-13. PMID:20561592. |
a reduction on brain-derived neurotrophic factor immunocontent and increased acetylcholinesterase activity in prefrontal cortex, but not in hippocampus, of rats treated with methylphenidate were also observed. |
2010-12-13 |
2023-08-12 |
rat |
| Emilene B S Scherer, Maira J da Cunha, Cristiane Matté, Felipe Schmitz, Carlos A Netto, Angela T S Wys. Methylphenidate affects memory, brain-derived neurotrophic factor immunocontent and brain acetylcholinesterase activity in the rat. Neurobiology of learning and memory. vol 94. issue 2. 2010-12-13. PMID:20561592. |
these results suggest that the deficit in spatial memory may be associated to decreased brain-derived neurotrophic factor immunocontent and increased acetylcholinesterase in prefrontal cortex of juvenile rats subjected to methylphenidate administration. |
2010-12-13 |
2023-08-12 |
rat |
| Francesco Matrisciano, Antonella M E Modafferi, Giuseppina I Togna, Ylenia Barone, Graziano Pinna, Ferdinando Nicoletti, Sergio Scaccianoc. Repeated anabolic androgenic steroid treatment causes antidepressant-reversible alterations of the hypothalamic-pituitary-adrenal axis, BDNF levels and behavior. Neuropharmacology. vol 58. issue 7. 2010-07-19. PMID:20138062. |
aas treatment reduced levels of brain-derived neurotrophic factor in the hippocampus and prefrontal cortex, reduced the expression of low-affinity glucocorticoid receptors in the hippocampus, and increased morning trough basal plasma corticosterone levels. |
2010-07-19 |
2023-08-12 |
rat |
| Jenny Wong, Maree J Webster, Hope Cassano, Cynthia S Weicker. Changes in alternative brain-derived neurotrophic factor transcript expression in the developing human prefrontal cortex. The European journal of neuroscience. vol 29. issue 7. 2009-08-27. PMID:19519623. |
changes in alternative brain-derived neurotrophic factor transcript expression in the developing human prefrontal cortex. |
2009-08-27 |
2023-08-12 |
human |
| T Kikusui, Y Mor. Behavioural and neurochemical consequences of early weaning in rodents. Journal of neuroendocrinology. vol 21. issue 4. 2009-08-10. PMID:19207810. |
neurochemically, the early-weaned male mice, but not female mice, show precocious myelination in the amygdala, decreased brain-derived neurotrophic factor protein levels in the hippocampus and prefrontal cortex, and reduced bromodeoxyuridine immunoreactivity in the dentate gyrus. |
2009-08-10 |
2023-08-12 |
mouse |
| Alexander Friedman, Michael Frankel, Yakov Flaumenhaft, Avia Merenlender, Albert Pinhasov, Yuval Feder, Michal Taler, Irit Gil-Ad, Moshe Abeles, Gal Yadi. Programmed acute electrical stimulation of ventral tegmental area alleviates depressive-like behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 4. 2009-03-23. PMID:18843267. |
these results were also highly correlated with increases in brain-derived neurotrophic factor mrna levels in the prefrontal cortex. |
2009-03-23 |
2023-08-12 |
rat |
| Paolo Follesa, Francesca Biggio, Giorgio Gorini, Stefania Caria, Giuseppe Talani, Laura Dazzi, Monica Puligheddu, Francesco Marrosu, Giovanni Biggi. Vagus nerve stimulation increases norepinephrine concentration and the gene expression of BDNF and bFGF in the rat brain. Brain research. vol 1179. 2008-01-17. PMID:17920573. |
we found that acute vagus nerve stimulation increased the expression of brain-derived neurotrophic factor and fibroblast growth factor in the hippocampus and cerebral cortex, decreased the abundance of nerve growth factor mrna in the hippocampus, and, similar to the antidepressant drug venlafaxine, increased the norepinephrine concentration in the prefrontal cortex. |
2008-01-17 |
2023-08-12 |
rat |