| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| John J Kopchick, Reetobrata Basu, Darlene E Berryman, Jens O L Jorgensen, Gudmundur Johannsson, Vishwajeet Pur. Covert actions of growth hormone: fibrosis, cardiovascular diseases and cancer. Nature reviews. Endocrinology. 2022-06-24. PMID:35750929. |
we highlight clinical data from patients with acromegaly or ghd, alongside data from cellular and animal studies, to reveal novel phenotypes and molecular pathways responsible for these actions of gh in fibrosis, cardiovascular function and cancer. |
2022-06-24 |
2023-08-14 |
human |
| Abdalla Elbialy, Kaidiliayi Sulidan, Afsana Bhuiyan, Yoji Igarashi, Kazutoshi Yoshitake, Dai Yamanouchi, Junsu Kang, Shuichi Asakawa, Shugo Watabe, Shigeharu Kinoshit. Induction of endoplasmic reticulum stress markers in an acromegaly model. Journal of cellular biochemistry. 2022-06-23. PMID:35734917. |
acromegaly is a growth hormone (gh) excess pathological condition in humans. |
2022-06-23 |
2023-08-14 |
zebrafish |
| Abdalla Elbialy, Kaidiliayi Sulidan, Afsana Bhuiyan, Yoji Igarashi, Kazutoshi Yoshitake, Dai Yamanouchi, Junsu Kang, Shuichi Asakawa, Shugo Watabe, Shigeharu Kinoshit. Induction of endoplasmic reticulum stress markers in an acromegaly model. Journal of cellular biochemistry. 2022-06-23. PMID:35734917. |
thus, our study emphasizes the importance of er stress in gh oversecretion, which is important for understanding the health complications of acromegaly. |
2022-06-23 |
2023-08-14 |
zebrafish |
| Ahmed Mohyeldin, Laurence J Katznelson, Andrew R Hoffman, Karam Asmaro, Saman S Ahmadian, Mostafa M Eltobgy, Jayakar V Nayak, Zara M Patel, Peter H Hwang, Juan C Fernandez-Mirand. Prospective intraoperative and histologic evaluation of cavernous sinus medial wall invasion by pituitary adenomas and its implications for acromegaly remission outcomes. Scientific reports. vol 12. issue 1. 2022-06-15. PMID:35705579. |
medial wall resection in acromegaly resulted in the highest potential for biochemical remission ever reported, with an average postoperative day 1 gh levels of 0.96 ug/l and surgical remission rates of 92% based on normalization of igf-1 levels after surgery (mean = 15.56 months; range 3-30 months). |
2022-06-15 |
2023-08-14 |
Not clear |
| Jonathan A Young, Shouan Zhu, Edward O List, Silvana Duran-Ortiz, Yosri Slama, Darlene E Berryma. Musculoskeletal Effects of Altered GH Action. Frontiers in physiology. vol 13. 2022-06-06. PMID:35665221. |
gh's effects have been studied in human conditions of gh alteration, such as acromegaly and laron syndrome, and gh therapies have been suggested to combat aging-related musculoskeletal diseases, in part, because of the decline in gh levels with advanced age. |
2022-06-06 |
2023-08-14 |
human |
| Connie B Newma. Effects of endocrine disorders on lipids and lipoproteins. Best practice & research. Clinical endocrinology & metabolism. 2022-06-02. PMID:35654682. |
acromegaly, gh deficiency, cushing syndrome, chronic glucocorticoid replacement, hypothyroidism, pcos and male hypogonadism can increase ldl-c and/or tg. |
2022-06-02 |
2023-08-14 |
Not clear |
| Connie B Newma. Effects of endocrine disorders on lipids and lipoproteins. Best practice & research. Clinical endocrinology & metabolism. 2022-06-02. PMID:35654682. |
acromegaly, gh deficiency, cushing syndrome, and chronic glucocorticoid replacement are associated with increased ascvd risk. |
2022-06-02 |
2023-08-14 |
Not clear |
| Connie B Newma. Effects of endocrine disorders on lipids and lipoproteins. Best practice & research. Clinical endocrinology & metabolism. 2022-06-02. PMID:35654682. |
treatment of acromegaly, gh deficiency, hypothyroidism, cushing syndrome, and testosterone deficiency reduce ldl-c, although statin therapy may still be needed. |
2022-06-02 |
2023-08-14 |
Not clear |
| Carolina Peixe, Miriam Sánchez-García, Ashley B Grossman, Márta Korbonits, Pedro Marque. Biochemical discrepancies in the evaluation of the somatotroph axis: Elevated GH or IGF-1 levels do not always diagnose acromegaly. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 64. 2022-05-24. PMID:35609487. |
biochemical discrepancies in the evaluation of the somatotroph axis: elevated gh or igf-1 levels do not always diagnose acromegaly. |
2022-05-24 |
2023-08-13 |
Not clear |
| Carolina Peixe, Miriam Sánchez-García, Ashley B Grossman, Márta Korbonits, Pedro Marque. Biochemical discrepancies in the evaluation of the somatotroph axis: Elevated GH or IGF-1 levels do not always diagnose acromegaly. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 64. 2022-05-24. PMID:35609487. |
the most frequent diagnosis underlying the finding of an elevated growth hormone (gh) and insulin-like growth factor-1 (igf-1) is acromegaly due to a gh-secreting pituitary tumour. |
2022-05-24 |
2023-08-13 |
Not clear |
| Carolina Peixe, Miriam Sánchez-García, Ashley B Grossman, Márta Korbonits, Pedro Marque. Biochemical discrepancies in the evaluation of the somatotroph axis: Elevated GH or IGF-1 levels do not always diagnose acromegaly. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 64. 2022-05-24. PMID:35609487. |
however, gh and igf-1 levels can be discordant in patients with acromegaly due to early or partially treated disease, or there might be another cause of high gh or high igf-1 unrelated to acromegaly, such as pre-analytical and technical pitfalls, physiological circumstances and pathological conditions. |
2022-05-24 |
2023-08-13 |
Not clear |
| Carolina Peixe, Miriam Sánchez-García, Ashley B Grossman, Márta Korbonits, Pedro Marque. Biochemical discrepancies in the evaluation of the somatotroph axis: Elevated GH or IGF-1 levels do not always diagnose acromegaly. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 64. 2022-05-24. PMID:35609487. |
high gh and normal or low serum igf-1, or alternatively, normal gh with elevated serum igf-1, should be carefully assessed to avoid misinterpreting the activity of acromegaly or misdiagnosing a patient with acromegaly. |
2022-05-24 |
2023-08-13 |
Not clear |
| Pedro Marques, Márta Korbonit. Approach to the Patient With Pseudoacromegaly. The Journal of clinical endocrinology and metabolism. vol 107. issue 6. 2022-05-18. PMID:34792134. |
pseudoacromegaly encompasses a heterogeneous group of conditions in which patients have clinical features of acromegaly or gigantism, but no excess of gh or igf-1. |
2022-05-18 |
2023-08-16 |
Not clear |
| Denise Costa, Tania D'Amico, Valeria Mercuri, Riccardo Schiaffini, Patrizia Gargiul. A new device for remote monitoring of vital parameters in acromegalic patients: pilot study. Endocrine, metabolic & immune disorders drug targets. 2022-05-17. PMID:35578869. |
acromegaly is a rare disease which results from growth hormone (gh) excess. |
2022-05-17 |
2023-08-13 |
Not clear |
| Iulia Potorac, Jean-François Bonneville, Adrian F Daly, Wouter de Herder, Patricia Fainstein-Day, Philippe Chanson, Marta Korbonits, Fernando Cordido, Elisa Baranski Lamback, Mohamed Abid, Véronique Raverot, Gerald Raverot, Emma Anda Apiñániz, Philippe Caron, Helene Du Boullay, Martin Bildingmaier, Marek Bolanowski, Marie Laloi-Michelin, Francoise Borson-Chazot, Olivier Chabre, Sophie Christin-Maitre, Claire Briet, Gonzalo Diaz-Soto, Fabrice Bonneville, Frederic Castinetti, Mônica R Gadelha, Nathalie Oliveira Santana, Maria Stelmachowska-Banaś, Tomas Gudbjartsson, Roció Villar-Taibo, Taiba Zornitzki, Luaba Tshibanda, Patrick Petrossians, Albert Becker. Pituitary MRI Features in Acromegaly due to Ectopic GHRH Secretion from a Neuroendocrine Tumor: Analysis of 30 cases. The Journal of clinical endocrinology and metabolism. 2022-05-05. PMID:35512251. |
this abnormal ghrh secretion drives growth hormone (gh) and insulin-like growth factor 1 (igf-1) excess, with a clinical presentation similar to classical pituitary acromegaly. |
2022-05-05 |
2023-08-13 |
Not clear |
| Iulia Potorac, Jean-François Bonneville, Adrian F Daly, Wouter de Herder, Patricia Fainstein-Day, Philippe Chanson, Marta Korbonits, Fernando Cordido, Elisa Baranski Lamback, Mohamed Abid, Véronique Raverot, Gerald Raverot, Emma Anda Apiñániz, Philippe Caron, Helene Du Boullay, Martin Bildingmaier, Marek Bolanowski, Marie Laloi-Michelin, Francoise Borson-Chazot, Olivier Chabre, Sophie Christin-Maitre, Claire Briet, Gonzalo Diaz-Soto, Fabrice Bonneville, Frederic Castinetti, Mônica R Gadelha, Nathalie Oliveira Santana, Maria Stelmachowska-Banaś, Tomas Gudbjartsson, Roció Villar-Taibo, Taiba Zornitzki, Luaba Tshibanda, Patrick Petrossians, Albert Becker. Pituitary MRI Features in Acromegaly due to Ectopic GHRH Secretion from a Neuroendocrine Tumor: Analysis of 30 cases. The Journal of clinical endocrinology and metabolism. 2022-05-05. PMID:35512251. |
identifying the underlying cause for the gh hypersecretion in the setting of ectopic ghrh excess is, however, essential for proper management both of acromegaly and the net. |
2022-05-05 |
2023-08-13 |
Not clear |
| Isabel Inacio, Liliana Fonseca, Ana Amado, Vania Benido, Isabel Ribeiro, Jorge Dores, Claudia Amaral, Maria Helena Cardos. Characteristics and treatment outcomes of micromegaly - acromegaly with apparently normal basal GH: A retrospective study and literature review. Endocrine regulations. vol 56. issue 2. 2022-04-30. PMID:35489048. |
characteristics and treatment outcomes of micromegaly - acromegaly with apparently normal basal gh: a retrospective study and literature review. |
2022-04-30 |
2023-08-13 |
Not clear |
| Rosa Maria Paragliola, Cinzia Carrozza, Salvatore M Corsello, Roberto Salvator. The biochemical diagnosis of acromegaly: revising the role of measurement of IGF-I and GH after glucose load in 5 questions. Expert review of endocrinology & metabolism. 2022-04-29. PMID:35485763. |
the biochemical diagnosis of acromegaly: revising the role of measurement of igf-i and gh after glucose load in 5 questions. |
2022-04-29 |
2023-08-13 |
Not clear |
| Rosa Maria Paragliola, Cinzia Carrozza, Salvatore M Corsello, Roberto Salvator. The biochemical diagnosis of acromegaly: revising the role of measurement of IGF-I and GH after glucose load in 5 questions. Expert review of endocrinology & metabolism. 2022-04-29. PMID:35485763. |
acromegaly is a rare disorder characterized by the excessive secretion of growth hormone (gh), mostly caused by pituitary adenomas. |
2022-04-29 |
2023-08-13 |
Not clear |
| Jakob Dal, Christian Rosendal, Jesper Karmisholt, Ulla Feldt-Rasmussen, Marianne Andersen, Marianne Klose, Claus Feldttoft, Ansgar Heck, Eigil H Nielsen, Jens O L Jørgense. Sex difference in patients with controlled acromegaly - a multicenter survey. Clinical endocrinology. 2022-04-27. PMID:35474467. |
active acromegaly is subject to sex differences in gh and igf-i patterns as well as clinical features but whether this also pertains to controlled disease is unclear. |
2022-04-27 |
2023-08-13 |
human |