| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jakob Dal, Christian Rosendal, Jesper Karmisholt, Ulla Feldt-Rasmussen, Marianne Andersen, Marianne Klose, Claus Feldttoft, Ansgar Heck, Eigil H Nielsen, Jens O L Jørgense. Sex difference in patients with controlled acromegaly - a multicenter survey. Clinical endocrinology. 2022-04-27. PMID:35474467. |
active acromegaly is subject to sex differences in gh and igf-i patterns as well as clinical features but whether this also pertains to controlled disease is unclear. |
2022-04-27 |
2023-08-13 |
human |
| Jiwon Kim, Yoon-A Hwang, Yae Won Park, Ju Hyung Moon, Eui Hyun Kim, Jae Won Hong, Eun Jig Lee, Cheol Ryong K. Revisiting growth hormone nadir cut-offs for remission in patients with acromegaly. European journal of endocrinology. vol 186. issue 6. 2022-04-26. PMID:35380987. |
over the past decade, the growth hormone (gh) nadir cut-off during the oral glucose tolerance test for remission in patients with acromegaly was changed from 0.4 to 1.0 μg/l due to the limited use of ultrasensitive detection kits to measure gh levels. |
2022-04-26 |
2023-08-16 |
Not clear |
| Jiwon Kim, Yoon-A Hwang, Yae Won Park, Ju Hyung Moon, Eui Hyun Kim, Jae Won Hong, Eun Jig Lee, Cheol Ryong K. Revisiting growth hormone nadir cut-offs for remission in patients with acromegaly. European journal of endocrinology. vol 186. issue 6. 2022-04-26. PMID:35380987. |
this retrospective study aimed to investigate the association between different gh nadir cut-offs and prognosis in patients with acromegaly. |
2022-04-26 |
2023-08-16 |
Not clear |
| Kevin C J Yuen, Susan L Samso. Oral Octreotide: A Review of Recent Clinical Trials and Practical Recommendations for Its Use in the Treatment of Patients With Acromegaly. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 2022-04-22. PMID:35452815. |
acromegaly is characterized by chronic growth hormone (gh) and insulin-like growth factor-i (igf-i) hypersecretion, often caused by a gh-secreting pituitary adenoma. |
2022-04-22 |
2023-08-13 |
Not clear |
| Gianmaria Salvio, Marianna Martino, Giancarlo Balercia, Giorgio Arnald. Acromegaly and male sexual health. Reviews in endocrine & metabolic disorders. 2022-04-02. PMID:35364803. |
acromegaly is a rare pathology characterized by chronic hypersecretion of growth hormone (gh) and insulin-like growth factor-1 (igf-1) that causes somatic, metabolic, and systemic changes. |
2022-04-02 |
2023-08-13 |
Not clear |
| Gianmaria Salvio, Marianna Martino, Giancarlo Balercia, Giorgio Arnald. Acromegaly and male sexual health. Reviews in endocrine & metabolic disorders. 2022-04-02. PMID:35364803. |
moreover, hypogonadism is also one of the factors linking acromegaly to erectile dysfunction (ed), but also metabolic complications of acromegaly and, probably, gh itself contribute to the genesis of this disorder. |
2022-04-02 |
2023-08-13 |
Not clear |
| Stefano Frara, Meliha Melin Uygur, Luigi di Filippo, Mauro Doga, Marco Losa, Simona Santoro, Pietro Mortini, Andrea Giustin. High Prevalence of Vertebral Fractures Associated with Preoperative GH Levels in Patients with recent Diagnosis of Acromegaly. The Journal of clinical endocrinology and metabolism. 2022-03-29. PMID:35349698. |
high prevalence of vertebral fractures associated with preoperative gh levels in patients with recent diagnosis of acromegaly. |
2022-03-29 |
2023-08-13 |
Not clear |
| Gherardo Mazziotti, Andrea G Lania, Ernesto Canali. Skeletal disorders associated with the growth hormone-insulin-like growth factor 1 axis. Nature reviews. Endocrinology. 2022-03-15. PMID:35288658. |
the consequence is an increased risk of fractures in individuals with ghd or acromegaly, a condition of gh excess. |
2022-03-15 |
2023-08-13 |
human |
| Anna Bogusławska, Aleksandra Gilis-Januszewska, Magdalena Godlewska, Andrzej Nowak, Jerzy Starzyk, Alicja Hubalewska-Dydejczy. Gender and age differences among patients with acromegaly. Polish archives of internal medicine. 2022-03-15. PMID:35289160. |
acromegaly is a chronic, slowly progressive disorder caused mostly by growth hormone (gh) -producing pituitary neuroendocrine tumors (pitnets). |
2022-03-15 |
2023-08-13 |
Not clear |
| E E Sakhnova, E G Przhiyalkovskaya, Zh E Belaya, G A Melnichenk. [Discordant parameters of insulin-like growth factor 1 and growth hormone in the diagnosis and monitoring of acromegaly]. Problemy endokrinologii. vol 68. issue 1. 2022-03-09. PMID:35262296. |
the tests for the diagnosis of acromegaly are measurement of both serum gh, and gh after oral glucose administration; serum insulin-like growth factor-1 (igf-1). |
2022-03-09 |
2023-08-13 |
Not clear |
| E E Sakhnova, E G Przhiyalkovskaya, Zh E Belaya, G A Melnichenk. [Discordant parameters of insulin-like growth factor 1 and growth hormone in the diagnosis and monitoring of acromegaly]. Problemy endokrinologii. vol 68. issue 1. 2022-03-09. PMID:35262296. |
this review discusses the prevalence of discordant gh and igf-1 outcomes in patients with acromegaly; factors causing this discrepancy; the impact of hormone levels on treatment outcomes. |
2022-03-09 |
2023-08-13 |
Not clear |
| Ravi Sonkar, Ryan Berry, Mary N Latimer, Sumanth D Prabhu, Martin E Young, Stuart J Fran. Augmented Cardiac Growth Hormone Signaling Contributes to Cardiomyopathy Following Genetic Disruption of the Cardiomyocyte Circadian Clock. Frontiers in pharmacology. vol 13. 2022-03-07. PMID:35250583. |
gh acts in part through induction of insulin-like growth factor 1 (igf1), and excess gh/igf1 signaling has been linked to pathologies such as insulin resistance, acromegaly, and cardiomyopathy. |
2022-03-07 |
2023-08-13 |
mouse |
| Joan Gil, Montserrat Marques-Pamies, Elena Valassi, Araceli García-Martínez, Guillermo Serra, Cristina Hostalot, Carmen Fajardo-Montañana, Cristina Carrato, Ignacio Bernabeu, Mónica Marazuela, Helena Rodríguez-Lloveras, Rosa Cámara, Isabel Salinas, Cristina Lamas, Betina Biagetti, Andreu Simó-Servat, Susan M Webb, Antonio Picó, Mireia Jordà, Manel Puig-Doming. Implications of Heterogeneity of Epithelial-Mesenchymal States in Acromegaly Therapeutic Pharmacologic Response. Biomedicines. vol 10. issue 2. 2022-02-25. PMID:35203668. |
acromegaly is caused by excess growth hormone (gh) produced by a pituitary tumor. |
2022-02-25 |
2023-08-13 |
Not clear |
| T Bonora, E Rigamonti, M Capoferri, M L De Pern. Acromegalic cardiomyopathy: a neglected cause of cardiomyopathy. La Clinica terapeutica. vol 173. issue 1. 2022-02-11. PMID:35147643. |
acromegaly represents a rare endocrine condition characterized by an excessive secretion of the growth hormone (gh) and the insulin-like growth factor-1 (igf-1), mostly subsequent to a pituitary adenoma. |
2022-02-11 |
2023-08-13 |
Not clear |
| Eva C Coopmans, Aart J van der Lely, Sebastian J C M M Negger. Approach to the patient with treatment resistant acromegaly. The Journal of clinical endocrinology and metabolism. 2022-01-28. PMID:35090028. |
acromegaly, if left untreated, is a rare and chronic disorder, commonly caused by a growth hormone (gh)-producing pituitary adenoma and is associated with significant comorbidities and an increased mortality. |
2022-01-28 |
2023-08-13 |
Not clear |
| Akira Taguchi, Yasuyuki Kinoshita, Atsushi Tominaga, Vishwa Jeet Amatya, Yukio Takeshima, Fumiyuki Yamasak. Metachronous Double Pituitary Adenoma with Altered Transcriptional Factor Profile: A Case Report and Literature Review. NMC case report journal. vol 8. issue 1. 2022-01-26. PMID:35079531. |
the endocrine evaluation confirmed acromegaly because of high serum levels of igf-1 and insufficient suppression of gh levels upon ogtt. |
2022-01-26 |
2023-08-13 |
Not clear |
| Gautami S Patel, Idan Grossmann, Kevin Rodriguez, Mridul Soni, Pranay K Joshi, Saawan C Patel, Devarashetty Shreya, Diana I Zamora, Ibrahim Sang. Acromegaly and the Colon: Scoping Beyond the Pituitary. Cureus. vol 13. issue 11. 2022-01-06. PMID:34987906. |
acromegaly is a complex endocrinological disorder commonly caused by hypersecretion of growth hormone (gh) typically due to pituitary gland tumors. |
2022-01-06 |
2023-08-13 |
Not clear |
| Elijah J Horesh, Jérémy Chéret, Ralf Pau. Growth Hormone and the Human Hair Follicle. International journal of molecular sciences. vol 22. issue 24. 2021-12-24. PMID:34948002. |
acromegaly, or gh excess, is associated with hypertrichosis, excessive androgen-independent growth of body hair, and hirsutism in females, while dysfunctional gh receptor-mediated signaling (laron syndrome) is associated with alopecia and prominent hf defects. |
2021-12-24 |
2023-08-13 |
human |
| Quanya Sun, Xiaoqing Li, Peili Chen, Lili Chen, Xiaolong Zha. The Beta-Cell Function and Glucose Profile of Newly Diagnosed Acromegalic Patients with Normal Glucose Tolerance. International journal of endocrinology. vol 2021. 2021-12-17. PMID:34917145. |
untreated acromegaly is a nature model for unveiling the diabetogenic effects of gh. |
2021-12-17 |
2023-08-13 |
Not clear |
| Sajjad Ali Khan, Nanik Ram, Muhammad Qamar Masood, Najmul Isla. Prevalence of Comorbidities among Patients with Acromegaly. Pakistan journal of medical sciences. vol 37. issue 7. 2021-12-16. PMID:34912391. |
acromegaly is a chronic disorder resulting from excessive secretion of growth hormone and (gh) and insulin-like growth factor 1 (igf-1) and is associated with several comorbidities. |
2021-12-16 |
2023-08-13 |
Not clear |