| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Erica L Schoeller, Daniel D Clark, Sandeepa Dey, Nathan V Cao, Sheila J Semaan, Ling W Chao, Alexander S Kauffman, Lisa Stowers, Pamela L Mello. Bmal1 Is Required for Normal Reproductive Behaviors in Male Mice. Endocrinology. vol 157. issue 12. 2017-05-26. PMID:27704948. |
we determined that bmal1 ko males also fail to display aggression and avoidance of predator scent, despite intact main olfactory function. |
2017-05-26 |
2023-08-13 |
mouse |
| Miwako Masugi-Tokita, Peter J Flor, Mitsuhiro Kawat. Metabotropic Glutamate Receptor Subtype 7 in the Bed Nucleus of the Stria Terminalis is Essential for Intermale Aggression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 3. 2016-10-06. PMID:26149357. |
to clarify the olfactory deficit, we then exposed mice to urine and analyzed c-fos-immunoreactivity, discovering a remarkable reduction in neural activity in the bed nucleus of the stria terminalis (bnst) of mglur7 ko mice. |
2016-10-06 |
2023-08-13 |
mouse |
| Hannah Kim, Yunjin Lee, Ji-Eun Kim, Pyung-Lim Ha. Reversal of an Unconditioned Behavioral Preference for Specific Food Pellets by Intervention of Whisker Sensory Inputs. Experimental neurobiology. vol 25. issue 2. 2016-04-28. PMID:27122994. |
recently, we reported that ac5 knockout (ko) mice preferred food pellets carrying an olfactory cue produced by ac5 ko mice during food consumption (ac5 ko pellets) over food pellets that had been taken by wildtype (wt) mice. |
2016-04-28 |
2023-08-13 |
mouse |
| K Marquardt, M Saha, M Mishina, J W Young, J L Brigma. Loss of GluN2A-containing NMDA receptors impairs extra-dimensional set-shifting. Genes, brain, and behavior. vol 13. issue 7. 2015-05-22. PMID:25059550. |
glun2a(ko) were not impaired on discrimination or reversal problems when tactile or olfactory stimuli were used, or when visual stimuli were sufficiently easy to discriminate. |
2015-05-22 |
2023-08-13 |
mouse |
| Alicia L Degano, Min Jung Park, Judith Penati, Qun Li, Gabriele V Ronnet. MeCP2 is required for activity-dependent refinement of olfactory circuits. Molecular and cellular neurosciences. vol 59. 2014-12-14. PMID:24472844. |
our results reveal defective postnatal refinement of olfactory circuits in mecp2 knock out (ko) mice after sensory (odorant) stimulation. |
2014-12-14 |
2023-08-12 |
mouse |
| S Mandillo, E Golini, D Marazziti, C Di Pietro, R Matteoni, G P Tocchini-Valentin. Mice lacking the Parkinson's related GPR37/PAEL receptor show non-motor behavioral phenotypes: age and gender effect. Genes, brain, and behavior. vol 12. issue 4. 2013-12-11. PMID:23574697. |
aged gpr37 ko female mice showed mild improvements in olfactory function, while anxiety and depression-like behaviors appeared to be significantly increased. |
2013-12-11 |
2023-08-12 |
mouse |
| Britto P Nathan, Michael Tonsor, Robert G Strubl. Long-term effects of estradiol replacement in the olfactory system. Experimental neurology. vol 237. issue 1. 2012-11-05. PMID:22691461. |
therefore we examined the effects of estradiol replacement following ovariectomy on expression of apoe and markers of cell proliferation, neuronal maturation, synaptogenesis and reactive gliosis in the primary olfactory pathway of wild-type (wt) and apoe knockout (ko) mice. |
2012-11-05 |
2023-08-12 |
mouse |
| L Calandreau, C Márquez, R Bisaz, M Fantin, C Sand. Differential impact of polysialyltransferase ST8SiaII and ST8SiaIV knockout on social interaction and aggression. Genes, brain, and behavior. vol 9. issue 8. 2011-03-02. PMID:20659171. |
stx ko mice displayed both a decreased social motivation and an increased aggressive behavior that cannot be explained by olfactory deficits. |
2011-03-02 |
2023-08-12 |
mouse |
| Britto P Nathan, Michael Tonsor, Robert G Strubl. Acute responses to estradiol replacement in the olfactory system of apoE-deficient and wild-type mice. Brain research. vol 1343. 2011-02-15. PMID:20447382. |
we examined the short-term effects of estradiol replacement in ovariectomized mice on apoe expression and markers for cell proliferation, reactive gliosis, neuronal maturation, and synaptogenesis in the primary olfactory pathway of wild-type (wt) and apoe knockout (ko) mice. |
2011-02-15 |
2023-08-12 |
mouse |
| Britto P Nathan, Salina Gairhe, Ikemefuna Nwosu, Stephen Clark, Robert G Strubl. Reconstitution of the olfactory epithelium following injury in apoE-deficient mice. Experimental neurology. vol 226. issue 1. 2010-10-28. PMID:20696162. |
rate of oe reconstitution in wt and ko mice was assessed by using three independent measures: (1) oe thickness was measured in cresyl-violet stained sections, (2) basal cell proliferation was determined by using bromodeoxyuridine (brdu) staining, and (3) differentiation and maturation of olfactory sensory neurons were measured by immunoblotting and immunohistochemical analysis of growth associated protein (gap) 43 and olfactory marker protein (omp). |
2010-10-28 |
2023-08-12 |
mouse |
| Steven Zukerman, Khalid Touzani, Robert F Margolskee, Anthony Sclafan. Role of olfaction in the conditioned sucrose preference of sweet-ageusic T1R3 knockout mice. Chemical senses. vol 34. issue 8. 2009-11-17. PMID:19736224. |
t1r3 ko and c57bl/6 wild-type (wt) mice were given 24-h sugar versus water tests with ascending concentrations of sucrose (0.5-32%), after which the mice received olfactory bulbectomy (obx) or sham surgery. |
2009-11-17 |
2023-08-12 |
mouse |
| E Dere, Q Zheng-Fischhöfer, D Viggiano, U A Gironi Carnevale, L A Ruocco, A Zlomuzica, M Schnichels, K Willecke, J P Huston, A G Sadil. Connexin31.1 deficiency in the mouse impairs object memory and modulates open-field exploration, acetylcholine esterase levels in the striatum, and cAMP response element-binding protein levels in the striatum and piriform cortex. Neuroscience. vol 153. issue 2. 2009-06-29. PMID:18384970. |
despite strong cx31.1 expression in the peripheral and central olfactory system, cx31.1 ko mice exhibited normal behavioral responses to an odor. |
2009-06-29 |
2023-08-12 |
mouse |
| Robert G Struble, Craig Cady, Britto P Nathan, Mary McAse. Apolipoprotein E may be a critical factor in hormone therapy neuroprotection. Frontiers in bioscience : a journal and virtual library. vol 13. 2008-09-19. PMID:18508594. |
results from numerous studies have demonstrated that (1) nerve regeneration is severely delayed in apoe-gene knockout (ko) mice as compared to wild-type (wt) littermates; (2) 17beta estradiol replacement in ovariectomized mice resulted in a significant increase in levels of apoe and lrp, in the olfactory bulb (ob) and other brain areas; (3) estradiol treatment increased both apoe and neurite outgrowth in cortical and olfactory neuronal cultures; and (4) estradiol treatment had no effect on neurite outgrowth in cultures deprived of apoe or in the presence of apoe4. |
2008-09-19 |
2023-08-12 |
mouse |
| John Larson, Daniel Kim, Roseanne C Patel, Christina Florean. Olfactory discrimination learning in mice lacking the fragile X mental retardation protein. Neurobiology of learning and memory. vol 90. issue 1. 2008-09-03. PMID:18289890. |
an automated training system was used to compare the behavior of knockout (ko) mice lacking the fragile x mental retardation protein with that of wild-type (wt) mice (c57bl/6 strain) in the acquisition and retention of olfactory discriminations. |
2008-09-03 |
2023-08-12 |
mouse |
| Nanaho Fukuda, Mika Shirasu, Koji Sato, Etsuko Ebisui, Kazushige Touhara, Katsuhiko Mikoshib. Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors. The European journal of neuroscience. vol 27. issue 10. 2008-08-20. PMID:18547250. |
we also found nasal inflammation and a decrease in olfactory capacity in ip3r2-r3 ko mice. |
2008-08-20 |
2023-08-12 |
mouse |
| Nanaho Fukuda, Mika Shirasu, Koji Sato, Etsuko Ebisui, Kazushige Touhara, Katsuhiko Mikoshib. Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors. The European journal of neuroscience. vol 27. issue 10. 2008-08-20. PMID:18547250. |
despite intact signal transduction in the olfactory epithelium, ip3r2-r3 ko mice exhibited elevated threshold sensitivity to odorants on in vivo imaging of olfactory glomerular responses and behavioral tests. |
2008-08-20 |
2023-08-12 |
mouse |
| David W Smith, Sokunthirith Thach, Erika L Marshall, Mary-Grace Mendoza, Steven J Kleen. Mice lacking NKCC1 have normal olfactory sensitivity. Physiology & behavior. vol 93. issue 1-2. 2008-04-22. PMID:17719611. |
to determine whether nkcc1 is required for normal olfactory sensitivity, olfactory sensitivity was compared between knockout (ko) mice carrying a null mutation for nkcc1 and wild-type (wt) littermates. |
2008-04-22 |
2023-08-12 |
mouse |
| J Moon, A E Beaudin, S Verosky, L L Driscoll, M Weiskopf, D A Levitsky, L S Crnic, B J Strup. Attentional dysfunction, impulsivity, and resistance to change in a mouse model of fragile X syndrome. Behavioral neuroscience. vol 120. issue 6. 2007-03-02. PMID:17201482. |
in the selective attention task, the unpredictable presentation of potent olfactory distractors produced a generalized disruption in the performance of the ko mice, whereas for controls, the disruption produced by the distractors was temporally limited. |
2007-03-02 |
2023-08-12 |
mouse |
| F A Chaillan, S Rivera, E Marchetti, J Jourquin, Z Werb, P D Soloway, M Khrestchatisky, F S Roma. Involvement of tissue inhibition of metalloproteinases-1 in learning and memory in mice. Behavioural brain research. vol 173. issue 2. 2006-11-01. PMID:16860884. |
we tested this hypothesis in a hippocampus-dependent task using the new olfactory tubing maze, with mice carrying a null mutation for timp-1 (timp-1 ko) and mice overexpressing timp-1 (timp-1 (tg)). |
2006-11-01 |
2023-08-12 |
mouse |
| Britto P Nathan, Johnathan Yost, Melissa T Litherland, Robert G Struble, Paul V Switze. Olfactory function in apoE knockout mice. Behavioural brain research. vol 150. issue 1-2. 2004-05-03. PMID:15033273. |
olfactory behavior of wild-type (wt) and apoe-deficient (apoe ko) mice was assessed by using three standard olfactory tests: (1) the buried food pellet (bfp) test; (2) the odor choice (oc) test; and (3) the odor cued taste avoidance (octa) test. |
2004-05-03 |
2023-08-12 |
mouse |