| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Nakahara, M Nakamura, H Furukawa, N Furun. Intracranial self-stimulation increases differentially in vivo hydroxylation of tyrosine but similarly in vivo hydroxylation of tryptophan in rat medial prefrontal cortex, nucleus accumbens and striatum. Brain research. vol 864. issue 1. 2000-08-11. PMID:10793194. |
we have examined using microdialysis the effect of intracranial self-stimulation (icss) on the in vivo hydroxylation rate of tyrosine and tryptophan in the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and striatum (str). |
2000-08-11 |
2023-08-12 |
rat |
| T R Franklin, J P Druha. Expression of Fos-related antigens in the nucleus accumbens and associated regions following exposure to a cocaine-paired environment. The European journal of neuroscience. vol 12. issue 6. 2000-08-11. PMID:10886349. |
rats in the paired group showed conditioned hyperactivity during the conditioning test, and this behavioural response was associated with increased fra expression within the caudal nac, the medial prefrontal cortex and the lateral septum relative to the unpaired and control groups. |
2000-08-11 |
2023-08-12 |
rat |
| T R Franklin, J P Druha. Expression of Fos-related antigens in the nucleus accumbens and associated regions following exposure to a cocaine-paired environment. The European journal of neuroscience. vol 12. issue 6. 2000-08-11. PMID:10886349. |
the correspondence between conditioned hyperactivity and enhanced fra expression within the caudal nac, the medial prefrontal cortex and lateral septum suggests that these regions may participate in the expression of conditioned responses to cocaine-related stimuli. |
2000-08-11 |
2023-08-12 |
rat |
| S Ikemoto, N E Goeder. Intra-medial prefrontal cortex injections of scopolamine increase instrumental responses for cocaine: an intravenous self-administration study in rats. Brain research bulletin. vol 51. issue 2. 2000-03-30. PMID:10709961. |
the present experiments examined the effects of muscarinic cholinergic receptor blockade in the nucleus accumbens (nac) and medial prefrontal cortex (mpc) on intravenous cocaine self-administration. |
2000-03-30 |
2023-08-12 |
rat |
| G Di Chiara, P Loddo, G Tand. Reciprocal changes in prefrontal and limbic dopamine responsiveness to aversive and rewarding stimuli after chronic mild stress: implications for the psychobiology of depression. Biological psychiatry. vol 46. issue 12. 2000-02-08. PMID:10624543. |
to investigate the role in depression of phasic dopamine transmission in cortical and limbic areas, we studied the effect of cms on the responsiveness of dopamine (da) transmission to aversive and rewarding stimuli in rats by microdialysis of the nucleus accumbens (nac) shell and of the medial prefrontal cortex (pfcx). |
2000-02-08 |
2023-08-12 |
human |
| J Ichikawa, H Y Meltze. R(+)-8-OH-DPAT, a serotonin(1A) receptor agonist, potentiated S(-)-sulpiride-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens but not striatum. The Journal of pharmacology and experimental therapeutics. vol 291. issue 3. 1999-12-20. PMID:10565846. |
the serotonin (5-ht)(2a/2c) receptor antagonist ritanserin has been reported to potentiate the dopamine (da) d(2/3) receptor antagonist raclopride-induced da release in medial prefrontal cortex (mpfc) and nucleus accumbens (nac) but not striatum (str). |
1999-12-20 |
2023-08-12 |
rat |
| W Lu, M E Wol. Repeated amphetamine administration alters AMPA receptor subunit expression in rat nucleus accumbens and medial prefrontal cortex. Synapse (New York, N.Y.). vol 32. issue 2. 1999-06-22. PMID:10231131. |
(1997) synapse 26:269-280] that repeated amphetamine administration alters ampa receptor subunit mrna levels in rat nucleus accumbens (nac) and medial prefrontal cortex (pfc). |
1999-06-22 |
2023-08-12 |
rat |
| T Kuroki, H Y Meltzer, J Ichikaw. Effects of antipsychotic drugs on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 288. issue 2. 1999-02-22. PMID:9918588. |
the present study was designed to compare the effects of typical and atypical antipsychotic drugs on extracellular dopamine (da) levels in the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), using in vivo microdialysis with dual probe implantation in awake, freely moving rats. |
1999-02-22 |
2023-08-12 |
rat |
| J Y Chang, P H Janak, D J Woodwar. Comparison of mesocorticolimbic neuronal responses during cocaine and heroin self-administration in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 8. 1998-04-20. PMID:9526026. |
to compare neuronal activity within the mesocorticolimbic circuit during the self-administration of cocaine and heroin, multiple-channel single-unit recordings of spike activity within the rat medial prefrontal cortex (mpfc) and nucleus accumbens (nac) were obtained during the consecutive self-administration of cocaine and heroin within the same session. |
1998-04-20 |
2023-08-12 |
rat |
| B E Hildebrand, G G Nomikos, P Hertel, B Schilström, T H Svensso. Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome. Brain research. vol 779. issue 1-2. 1998-04-02. PMID:9473676. |
withdrawal from chronic treatment with various types of addictive drugs, including amphetamine, cocaine, ethanol and morphine is associated with a decrease in dopaminergic output in the nucleus accumbens (nac), whereas the effects of withdrawal from these drugs on dopaminergic output in the medial prefrontal cortex (pfc), as yet, remain largely unknown. |
1998-04-02 |
2023-08-12 |
rat |
| M Nisell, G G Nomikos, K Chergui, P Grillner, T H Svensso. Chronic nicotine enhances basal and nicotine-induced Fos immunoreactivity preferentially in the medial prefrontal cortex of the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 17. issue 3. 1998-01-08. PMID:9272482. |
in the present study, expression of the immediate early gene protein products fos and jun-b within the dorsolateral striatum, the core and shell of the nucleus accumbens (nac), the medial prefrontal cortex (mpfc), and the ventrolateral orbital cortex was examined. |
1998-01-08 |
2023-08-12 |
rat |
| V Bassareo, G Di Chiar. Differential influence of associative and nonassociative learning mechanisms on the responsiveness of prefrontal and accumbal dopamine transmission to food stimuli in rats fed ad libitum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 2. 1997-11-28. PMID:8987806. |
feeding a novel food (fonzies) to rats fed ad libitum with standard food increased extracellular dopamine (da) in the medial prefrontal cortex (pfcx) and in the medial nucleus accumbens (nac). |
1997-11-28 |
2023-08-12 |
rat |
| M M Marcus, G G Nomikos, A Malmerfelt, O Zachrisson, N Lindefors, T H Svensso. Effect of chronic antipsychotic drug treatment on preprosomatostatin and preprotachykinin A mRNA levels in the medial prefrontal cortex, the nucleus accumbens and the caudate putamen of the rat. Brain research. Molecular brain research. vol 45. issue 2. 1997-08-07. PMID:9149102. |
in situ hybridization histochemistry was used to study the expression of preprosomatostatin (ppsom) and preprotachykinin a (ppt-a) mrna in the medial prefrontal cortex (mpfc), the nucleus accumbens (nac) and the caudate putamen (cp) of the rat after chronic (21 days) treatment with the classical antipsychotic drug haloperidol (1 mg/kg i.p. |
1997-08-07 |
2023-08-12 |
rat |
| P Hertel, G G Nomikos, M Iurlo, T H Svensso. Risperidone: regional effects in vivo on release and metabolism of dopamine and serotonin in the rat brain. Psychopharmacology. vol 124. issue 1-2. 1997-01-29. PMID:8935802. |
the nucleus accumbens (nac), the medial prefrontal cortex (mpc) and the lateral striatum (str). |
1997-01-29 |
2023-08-12 |
rat |
| G Panagis, M Nisell, G G Nomikos, K Chergui, T H Svensso. Nicotine injections into the ventral tegmental area increase locomotion and Fos-like immunoreactivity in the nucleus accumbens of the rat. Brain research. vol 730. issue 1-2. 1997-01-28. PMID:8883897. |
intra-tegmental injections of nicotine (8.0 micrograms/side) increased fos-like immunoreactivity in the nac, but did not affect the number of fos-positive nuclei in the medial prefrontal cortex or in the dorsolateral striatum. |
1997-01-28 |
2023-08-12 |
rat |
| M E Benwell, P E Holtom, R J Moran, D J Balfou. Neurochemical and behavioural interactions between ibogaine and nicotine in the rat. British journal of pharmacology. vol 117. issue 4. 1996-07-24. PMID:8646423. |
administration of ibogaine was associated with reductions in the tissue levels of 5-hydroxyindoleacetic acid (5-hiaa) in the nac (p < 0.01) and striatum (p < 0.05) and an increase in the level of this metabolite in the medial prefrontal cortex (mpfc) (p < 0.01) while the levels of dopamine and 5-hydroxytryptamine (5-ht) in the mpfc were reduced (p < 0.05). |
1996-07-24 |
2023-08-12 |
rat |
| G G Nomikos, M Iurlo, J L Andersson, K Kimura, T H Svensso. Systemic administration of amperozide, a new atypical antipsychotic drug, preferentially increases dopamine release in the rat medial prefrontal cortex. Psychopharmacology. vol 115. issue 1-2. 1995-03-20. PMID:7862887. |
by employing microdialysis, we examined the effects of apz on extracellular concentrations of da in the nucleus accumbens (nac), the dorsolateral striatum (str) and the medial prefrontal cortex (mpc) of awake rats. |
1995-03-20 |
2023-08-12 |
rat |
| J R Walker, K A Sevarin. Regulation of cytochrome c oxidase subunit mRNA and enzyme activity in rat brain reward regions during withdrawal from chronic cocaine. Journal of neurochemistry. vol 64. issue 2. 1995-02-21. PMID:7830041. |
co activity, used as a measure of metabolic activity, was increased by 88% in the nac, and decreased by 20% in the medial prefrontal cortex (mpfc), the day after chronic treatment was terminated. |
1995-02-21 |
2023-08-12 |
rat |
| J N Carlson, L W Fitzgerald, R W Keller, S D Glic. Lateralized changes in prefrontal cortical dopamine activity induced by controllable and uncontrollable stress in the rat. Brain research. vol 630. issue 1-2. 1994-04-05. PMID:8118684. |
among these is the activation of dopamine-containing neuronal systems projecting to the medial prefrontal cortex (pfc), to a lesser extent the nucleus accumbens (nac) and, in a few studies, the striatum. |
1994-04-05 |
2023-08-12 |
rat |
| P A Garris, R M Wightma. Different kinetics govern dopaminergic transmission in the amygdala, prefrontal cortex, and striatum: an in vivo voltammetric study. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 1. 1994-02-16. PMID:8283249. |
transient electrical stimulation of ascending da fibers in a near physiological range of frequencies (10-20 hz) elicited similar levels of extracellular da in the medial prefrontal cortex (mpfc), basal lateral amygdaloid nucleus (ban), caudate-putamen (cp), and nucleus accumbens (nac) despite the documented 90-fold disparity in da tissue levels and terminal density. |
1994-02-16 |
2023-08-12 |
Not clear |