| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takayuki Nakagawa, Shuji Kanek. Neuropsychotoxicity of abused drugs: molecular and neural mechanisms of neuropsychotoxicity induced by methamphetamine, 3,4-methylenedioxymethamphetamine (ecstasy), and 5-methoxy-N,N-diisopropyltryptamine (foxy). Journal of pharmacological sciences. vol 106. issue 1. 2008-03-04. PMID:18198474. |
several lines of evidence suggest that their chronic treatment leads to the enhancement of the mesocorticolimbic dopaminergic neurons from the ventral tegmental area (vta) to the nucleus accumbens (nac) and the medial prefrontal cortex (mpfc) and leads to abnormal glutamatergic function from the mpfc to the nac and vta. |
2008-03-04 |
2023-08-12 |
xenopus_laevis |
| Elisa S Na, Michael J Morris, Ralph F Johnson, Terry G Beltz, Alan Kim Johnso. The neural substrates of enhanced salt appetite after repeated sodium depletions. Brain research. vol 1171. 2008-01-11. PMID:17822683. |
fos-ir activity was quantified in the paraventricular nucleus (pvn), subfornical organ (sfo), supraoptic nucleus (son), nucleus accumbens (nac) shell and core, basolateral (bla) and central amygdala (cea), and medial prefrontal cortex (mpfc). |
2008-01-11 |
2023-08-12 |
rat |
| Dean Sabatinelli, Margaret M Bradley, Peter J Lang, Vincent D Costa, Francesco Versac. Pleasure rather than salience activates human nucleus accumbens and medial prefrontal cortex. Journal of neurophysiology. vol 98. issue 3. 2008-01-07. PMID:17596422. |
here we find in two studies that free viewing of pleasant images of erotic and romantic couples prompts clear, reliable increases in nucleus accumbens (nac) and medial prefrontal cortex (mpfc) activity, whereas equally arousing (salient) unpleasant images, and neutral pictures, do not. |
2008-01-07 |
2023-08-12 |
human |
| M A De Luca, V Bassareo, A Bauer, G Di Chiar. Caffeine and accumbens shell dopamine. Journal of neurochemistry. vol 103. issue 1. 2007-11-07. PMID:17655660. |
to clarify this issue rats were implanted with microdialysis probes at different sites in the nac shell, in the medial prefrontal cortex (pfcx, infralimbic cortex), and at the border between those areas. |
2007-11-07 |
2023-08-12 |
rat |
| Xiu-Ti H. Cocaine withdrawal and neuro-adaptations in ion channel function. Molecular neurobiology. vol 35. issue 1. 2007-10-23. PMID:17519508. |
chronic exposure to psychostimulants induces neuro-adaptations in ion channel function of dopamine (da)-innervated cells localized within the medial prefrontal cortex (mpfc) and nucleus accumbens (nac). |
2007-10-23 |
2023-08-12 |
human |
| Qiang Chen, Tong H Lee, William C Wetsel, Qi-An Sun, Yingmiao Liu, Colin Davidson, Xueying Xiong, Everett H Ellinwood, Xiuwu Zhan. Reversal of cocaine sensitization-induced behavioral sensitization normalizes GAD67 and GABAA receptor alpha2 subunit expression, and PKC zeta activity. Biochemical and biophysical research communications. vol 356. issue 3. 2007-06-06. PMID:17382295. |
results revealed that glutamic acid decarboxylase (gad(65)/gad(67)) is higher abundant in the nucleus accumbens (nac) than that in the caudate and medial prefrontal cortex (mpfc), while gaba(a) receptor alpha2 subunit level in the nac shell is less abundant than that in the nac core, mpfc and caudate. |
2007-06-06 |
2023-08-12 |
rat |
| Wei-Ming Lue, Eagle Yi-Kung Huang, San-Nan Yang, Chih-Shung Wong, Pao-Luh Ta. Post-treatment of dextromethorphan reverses morphine effect on conditioned place preference in rats. Synapse (New York, N.Y.). vol 61. issue 6. 2007-06-01. PMID:17372963. |
the dopamine (da) turnover rate in the nac, dorsal striatum (ds) and medial prefrontal cortex (mpfc) was increased after subchronic morphine treatment. |
2007-06-01 |
2023-08-12 |
rat |
| Takashi Uehara, Tomiki Sumiyoshi, Tadasu Matsuoka, Hiroko Itoh, Masayoshi Kurach. Effect of prefrontal cortex inactivation on behavioral and neurochemical abnormalities in rats with excitotoxic lesions of the entorhinal cortex. Synapse (New York, N.Y.). vol 61. issue 6. 2007-06-01. PMID:17372984. |
)-induced dopamine (da) release in the nucleus accumbens (nac) and the basolateral amygdala (bla), as well as locomotor activity and prepulse inhibition (ppi), was measured following microinfusion of lidocaine or the cerebrospinal fluid (csf) into the medial prefrontal cortex (mpfc). |
2007-06-01 |
2023-08-12 |
human |
| Evan P Sleipness, Barbara A Sorg, Heiko T Janse. Diurnal differences in dopamine transporter and tyrosine hydroxylase levels in rat brain: dependence on the suprachiasmatic nucleus. Brain research. vol 1129. issue 1. 2007-03-22. PMID:17156761. |
we used western blots to measure expression of dopamine transporter (dat) and tyrosine hydroxylase (th) proteins in the medial prefrontal cortex (mpfc), nucleus accumbens (nac), and caudate in sham and scn-lesioned (scnx) rats at zt4 (zeitgeber time 4, 4 h after lights-on) or zt20 (8 h after lights-off). |
2007-03-22 |
2023-08-12 |
rat |
| Sanjeev K Bhardwaj, Clifford M Cassidy, Lalit K Srivastav. Changes in syntaxin-1B mRNA in the nucleus accumbens of amphetamine-sensitized rats. The international journal of neuropsychopharmacology. vol 9. issue 6. 2007-02-26. PMID:16359582. |
results show that the expression of syntaxin-1b mrna was significantly increased in the nac shell (nacs) region in the amphetamine-sensitized rats 14 d after the drug treatment compared to saline pretreated or untreated control animals no significant change in syntaxin-1b mrna was observed in animals sacrificed 24 h or 7 d after the sensitizing regimen of amphetamine in any brain region analysed, namely nacs, nac core (nacc), caudate putamen (cpu), ventral tegmental area (vta) or medial prefrontal cortex (mpfc). |
2007-02-26 |
2023-08-12 |
rat |
| Taylor Moran-Gates, Carla Massari, Amaury Graulich, Jean-François Liégeois, Frank I Taraz. Long-term effects of JL 13, a potential atypical antipsychotic, on rat dopamine and serotonin receptor subtypes. Journal of neuroscience research. vol 84. issue 3. 2006-11-01. PMID:16810690. |
similar to other typical and atypical antipsychotics, jl 13 increased labeling of d(2) receptors in medial prefrontal cortex (mpc) and hippocampus (hip) and d(4) receptors in nucleus accumbens (nac), caudate-putamen (cpu), and hip. |
2006-11-01 |
2023-08-12 |
rat |
| E Koya, Sabine Spijker, Pieter Voorn, Rob Binnekade, E Donne Schmidt, Anton N M Schoffelmeer, Taco J De Vries, August B Smi. Enhanced cortical and accumbal molecular reactivity associated with conditioned heroin, but not sucrose-seeking behaviour. Journal of neurochemistry. vol 98. issue 3. 2006-09-08. PMID:16787418. |
re-exposure to the cue after 3 weeks of withdrawal reinstated heroin-seeking behaviour, which resulted in ieg expression of ania-3, mkp-1, c-fos and nr4a3 in the medial prefrontal cortex (mpfc), and of ania-3 in the orbital frontal cortex (ofc) and nucleus accumbens core (nac). |
2006-09-08 |
2023-08-12 |
Not clear |
| Amani Eltayb, Marie-Louise G Wadenberg, Björn Schilström, Torgny H Svensso. Topiramate augments the antipsychotic-like effect and cortical dopamine output of raclopride. Naunyn-Schmiedeberg's archives of pharmacology. vol 372. issue 3. 2006-07-20. PMID:16284783. |
we also examined the effect of this drug treatment on da release in the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), using in vivo microdialysis in freely moving animals. |
2006-07-20 |
2023-08-12 |
rat |
| Elyssa B Margolis, Hagar Lock, Vladimir I Chefer, Toni S Shippenberg, Gregory O Hjelmstad, Howard L Field. Kappa opioids selectively control dopaminergic neurons projecting to the prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 8. 2006-06-13. PMID:16477003. |
two major targets of these afferents are the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac). |
2006-06-13 |
2023-08-12 |
Not clear |
| Zhu Li, Junji Ichikawa, Mei Huang, Adam J Prus, Jin Dai, Herbert Y Meltze. ACP-103, a 5-HT2A/2C inverse agonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Psychopharmacology. vol 183. issue 2. 2006-04-13. PMID:16220333. |
previous studies from this laboratory using microdialysis have shown that pretreatment of the 5-ht(2a) antagonist m100907 with the typical apd and d(2) antagonist haloperidol produced an increase in the medial prefrontal cortex (mpfc), but not in the nucleus accumbens (nac), da release. |
2006-04-13 |
2023-08-12 |
rat |
| María Ramos, Beatriz Goñi-Allo, Norberto Aguirr. Ibotenic acid lesions of the medial prefrontal cortex block the development and expression of 3,4-methylenedioxymethamphetamine-induced behavioral sensitization in rats. Behavioural brain research. vol 160. issue 2. 2005-07-15. PMID:15863226. |
more specifically the glutamatergic input from the medial prefrontal cortex (mpfc) to the vta and the nac appears to be involved in behavioral sensitization processes. |
2005-07-15 |
2023-08-12 |
rat |
| C W Stevenson, Alain Gratto. Role of basolateral amygdala dopamine in modulating prepulse inhibition and latent inhibition in the rat. Psychopharmacology. vol 176. issue 2. 2005-02-17. PMID:15114433. |
the dopamine (da) projection to the basolateral amygdala (bla) modulates nucleus accumbens (nac) and medial prefrontal cortex (mpfc) da transmission. |
2005-02-17 |
2023-08-12 |
rat |
| Yi-Qing Mo, Xi-Lu Jin, You-Ting Chen, Guo-Zhang Jin, Wei-Xing Sh. Effects of l-stepholidine on forebrain Fos expression: comparison with clozapine and haloperidol. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 2. 2005-02-15. PMID:15578005. |
), spd induced fos expression in the medial prefrontal cortex (mpfc), nucleus accumbens (nac), and lateral septal nucleus (lsn) without significantly affecting the dorsolateral striatum (dlst). |
2005-02-15 |
2023-08-12 |
Not clear |
| Young-Chul Chung, Zhu Li, Jin Dai, Herbert Y Meltzer, Junji Ichikaw. Clozapine increases both acetylcholine and dopamine release in rat ventral hippocampus: role of 5-HT1A receptor agonism. Brain research. vol 1023. issue 1. 2004-12-21. PMID:15364019. |
this advantage has been attributed, in part, to the ability of the atypical apds to markedly increase acetylcholine (ach) and dopamine (da) release in rat medial prefrontal cortex (mpfc), while producing a minimal effect in the nucleus accumbens (nac) or striatum. |
2004-12-21 |
2023-08-12 |
rat |
| G N Neigh, H M Arnold, R L Rabenstein, M Sarter, J P Brun. Neuronal activity in the nucleus accumbens is necessary for performance-related increases in cortical acetylcholine release. Neuroscience. vol 123. issue 3. 2004-03-31. PMID:14706776. |
upon reaching a consistent level of performance, rats were implanted with microdialysis cannula in the medial prefrontal cortex (mpfc) and either the ipsilateral shell of the nac or in the dorsal striatum (str; control site). |
2004-03-31 |
2023-08-12 |
rat |