| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrew C Meyer, Nichole M Neugebauer, Guangrong Zheng, Peter A Crooks, Linda P Dwoskin, Michael T Bard. Effects of VMAT2 inhibitors lobeline and GZ-793A on methamphetamine-induced changes in dopamine release, metabolism and synthesis in vivo. Journal of neurochemistry. vol 127. issue 2. 2013-12-02. PMID:23875705. |
meth also increased tissue da synthesis in nac and striatum, whereas gz-793a decreased synthesis; no effect of meth or gz-793a on da synthesis was found in medial prefrontal cortex or orbitofrontal cortex. |
2013-12-02 |
2023-08-12 |
rat |
| Zisis Bimpisidis, Maria Antonietta De Luca, Augusta Pisanu, Gaetano Di Chiar. Lesion of medial prefrontal dopamine terminals abolishes habituation of accumbens shell dopamine responsiveness to taste stimuli. The European journal of neuroscience. vol 37. issue 4. 2013-11-04. PMID:23216547. |
taste stimuli increase extracellular dopamine (da) in the nucleus accumbens (nac) and in the medial prefrontal cortex (mpfc). |
2013-11-04 |
2023-08-12 |
rat |
| Pauline Belujon, Mary H Patton, Anthony A Grac. Disruption of prefrontal cortical-hippocampal balance in a developmental model of schizophrenia: reversal by sulpiride. The international journal of neuropsychopharmacology. vol 16. issue 3. 2013-10-31. PMID:23067577. |
the nucleus accumbens (nac) receives converging inputs from the medial prefrontal cortex (mpfc) and the hippocampus which have competitive interactions in the nac to influence motivational drive. |
2013-10-31 |
2023-08-12 |
Not clear |
| Amy A Herrold, Amanda L Persons, T Celeste Napie. Cellular distribution of AMPA receptor subunits and mGlu5 following acute and repeated administration of morphine or methamphetamine. Journal of neurochemistry. vol 126. issue 4. 2013-10-23. PMID:23711322. |
step61 levels, and cellular distribution/expression of ampar subunits (glua1, glua2) and mglu5, were evaluated via a protein cross-linking assay in medial prefrontal cortex (mpfc), nucleus accumbens (nac), and ventral pallidum (vp) harvested 1 day after acute, or fourteen days after repeated morphine (8 mg/kg) or methamphetamine (1 mg/kg) (treatments producing behavioral sensitization). |
2013-10-23 |
2023-08-12 |
rat |
| V Valentini, G Piras, M A De Luca, V Perra, F Bordi, F Borsini, R Frau, G Di Chiar. Evidence for a role of a dopamine/5-HT6 receptor interaction in cocaine reinforcement. Neuropharmacology. vol 65. 2013-10-17. PMID:22982249. |
the putative 5-ht6 receptor agonist st1936 has been shown to increase extracellular dopamine (da) in the n.accumbens (nac) shell and in the medial prefrontal cortex (pfcx). |
2013-10-17 |
2023-08-12 |
rat |
| Jocelyn M Richard, Kent C Berridg. Prefrontal cortex modulates desire and dread generated by nucleus accumbens glutamate disruption. Biological psychiatry. vol 73. issue 4. 2013-07-12. PMID:22981656. |
here, we asked whether medial prefrontal cortex can modulate intense motivations generated by subcortical nac disruptions. |
2013-07-12 |
2023-08-12 |
rat |
| Changjiu Zhao, Ming L. Neuroanatomical substrates of the disruptive effect of olanzapine on rat maternal behavior as revealed by c-Fos immunoreactivity. Pharmacology, biochemistry, and behavior. vol 103. issue 2. 2013-06-11. PMID:22960130. |
acute olanzapine treatment dose-dependently disrupted various components of maternal behavior (e.g., pup retrieval, pup licking, nest building, crouching) and increased c-fos immunoreactivity in the medial prefrontal cortex (mpfc), nucleus accumbens shell and core (nas and nac), dorsolateral striatum (dlst), ventral lateral septum (lsv), central amygdala (cea) and ventral tegmental area (vta), important brain areas generally implicated in the incentive motivation and reward processing. |
2013-06-11 |
2023-08-12 |
human |
| Florence R M Theberge, Charles L Pickens, Evan Goldart, Sanya Fanous, Bruce T Hope, Qing-Rong Liu, Yavin Shaha. Association of time-dependent changes in mu opioid receptor mRNA, but not BDNF, TrkB, or MeCP2 mRNA and protein expression in the rat nucleus accumbens with incubation of heroin craving. Psychopharmacology. vol 224. issue 4. 2013-05-10. PMID:22790874. |
we investigated whether this incubation is associated with time-dependent changes in brain-derived neurotrophic factor (bdnf) and methyl-cpg binding protein 2 (mecp2) signaling and mu opioid receptor (mor) expression in nucleus accumbens (nac), dorsal striatum (ds), and medial prefrontal cortex (mpfc). |
2013-05-10 |
2023-08-12 |
rat |
| Xiao Han, Nanxin Li, Xiaofang Xue, Feng Shao, Weiwen Wan. Early social isolation disrupts latent inhibition and increases dopamine D2 receptor expression in the medial prefrontal cortex and nucleus accumbens of adult rats. Brain research. vol 1447. 2013-04-30. PMID:22341870. |
in the present study, we investigated the effects of peri-adolescent social isolation on latent inhibition (li) and dopamine d2 receptor expression in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) of young adult rats. |
2013-04-30 |
2023-08-12 |
rat |
| Dipesh Chaudhury, Jessica J Walsh, Allyson K Friedman, Barbara Juarez, Stacy M Ku, Ja Wook Koo, Deveroux Ferguson, Hsing-Chen Tsai, Lisa Pomeranz, Daniel J Christoffel, Alexander R Nectow, Mats Ekstrand, Ana Domingos, Michelle S Mazei-Robison, Ezekiell Mouzon, Mary Kay Lobo, Rachael L Neve, Jeffrey M Friedman, Scott J Russo, Karl Deisseroth, Eric J Nestler, Ming-Hu Ha. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature. vol 493. issue 7433. 2013-03-04. PMID:23235832. |
furthermore, we show differences in projection-pathway specificity in promoting stress susceptibility: phasic activation of vta neurons projecting to the nucleus accumbens (nac), but not to the medial prefrontal cortex (mpfc), induced susceptibility to social-defeat stress. |
2013-03-04 |
2023-08-12 |
mouse |
| Yosefu Arime, Yoshiyuki Kasahara, F Scott Hall, George R Uhl, Ichiro Sor. Cortico-subcortical neuromodulation involved in the amelioration of prepulse inhibition deficits in dopamine transporter knockout mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 11. 2013-02-26. PMID:22781838. |
to clarify these mechanisms, ppi was tested after microinjections of nisoxetine into the medial prefrontal cortex (mpfc) or nucleus accumbens (nac) in wildtype (wt) and dat ko mice. |
2013-02-26 |
2023-08-12 |
mouse |
| J Luigjes, W van den Brink, M Feenstra, P van den Munckhof, P R Schuurman, R Schippers, A Mazaheri, T J De Vries, D Deny. Deep brain stimulation in addiction: a review of potential brain targets. Molecular psychiatry. vol 17. issue 6. 2012-11-07. PMID:21931318. |
we found 7 animal studies targeting six different brain areas: nucleus accumbens (nac), subthalamic nucleus (stn), dorsal striatum, lateral habenula, medial prefrontal cortex (mpfc) and hypothalamus, and 11 human studies targeting two different target areas: nac and stn. |
2012-11-07 |
2023-08-12 |
human |
| A Muhammad, C Carroll, B Kol. Stress during development alters dendritic morphology in the nucleus accumbens and prefrontal cortex. Neuroscience. vol 216. 2012-10-17. PMID:22542675. |
rats exposed to stress during embryonic development (prenatal stress; ps) or soon after birth (maternal separation; ms) were studied for structural alteration at the neuronal level in the nucleus accumbens (nac), orbital frontal cortex (ofc), and medial prefrontal cortex (mpfc). |
2012-10-17 |
2023-08-12 |
rat |
| R Charles Lawrence, Nicha K H Otero, Sandra J Kell. Selective effects of perinatal ethanol exposure in medial prefrontal cortex and nucleus accumbens. Neurotoxicology and teratology. vol 34. issue 1. 2012-10-15. PMID:21871563. |
previous behavioral findings using rat models of fasd have suggested that there are changes in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) following ethanol exposure during development. |
2012-10-15 |
2023-08-12 |
rat |
| J Kleijn, J Wiskerke, T I F H Cremers, A N M Schoffelmeer, B H C Westerink, T Patti. Effects of amphetamine on dopamine release in the rat nucleus accumbens shell region depend on cannabinoid CB1 receptor activation. Neurochemistry international. vol 60. issue 8. 2012-10-12. PMID:22426202. |
the behavioral effects of the psychostimulant drug amphetamine depend on its ability to increase monoamine neurotransmission in brain regions such as the nucleus accumbens (nac) and medial prefrontal cortex (mpfc). |
2012-10-12 |
2023-08-12 |
rat |
| A Fink-Jensen, L Hansen, J B Hansen, E B Nielse. Regional differences in the effect of haloperidol and atypical neuroleptics on interstitial levels of DOPAC in the rat forebrain: an in vivo microdialysis study. Journal of psychopharmacology (Oxford, England). vol 10. issue 2. 2012-10-02. PMID:22302888. |
the effect of 'typical' and 'atypical' neuroleptics on interstitial levels of the dopamine metabolite 3,4- dihydroxyphenylacetic acid ([dopac]e) in the dorsolateral striatum (dlst), the nucleus accumbens (nac) and the medial prefrontal cortex (pfc) was investigated in awake rats by use of the microdialysis technique. |
2012-10-02 |
2023-08-12 |
rat |
| Yu-Chun Wang, Ue-Cheung Ho, Meng-Ching Ko, Chun-Chieh Liao, Li-Jen Le. Differential neuronal changes in medial prefrontal cortex, basolateral amygdala and nucleus accumbens after postweaning social isolation. Brain structure & function. vol 217. issue 2. 2012-09-04. PMID:22002740. |
the mesocorticolimbic system contains dopamine (da)-producing neurons in the ventral tegmental area (vta) and their projection targets, including the medial prefrontal cortex (mpfc), amygdala (amy) and nucleus accumbens (nac). |
2012-09-04 |
2023-08-12 |
rat |
| Osama A Abulseoud, Joseph D Miller, Jinhua Wu, Doo-Sup Choi, Daniel P Holschneide. Ceftriaxone upregulates the glutamate transporter in medial prefrontal cortex and blocks reinstatement of methamphetamine seeking in a condition place preference paradigm. Brain research. vol 1456. 2012-08-23. PMID:22521042. |
using real time pcr, eaat₂ mrna levels in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) were quantified in response to ceftriaxone. |
2012-08-23 |
2023-08-12 |
human |
| David J Hinton, Moonnoh R Lee, Taylor L Jacobson, Prasanna K Mishra, Mark A Frye, David A Mrazek, Slobodan I Macura, Doo-Sup Cho. Ethanol withdrawal-induced brain metabolites and the pharmacological effects of acamprosate in mice lacking ENT1. Neuropharmacology. vol 62. issue 8. 2012-08-10. PMID:22616110. |
to investigate the effect of acamprosate on brain metabolites in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac), we employed in vivo 16.4 t proton magnetic resonance spectroscopy. |
2012-08-10 |
2023-08-12 |
mouse |
| Amy A Herrold, Robin M Voigt, T Celeste Napie. Brain region-selective cellular redistribution of mGlu5 but not GABA(B) receptors following methamphetamine-induced associative learning. Synapse (New York, N.Y.). vol 65. issue 12. 2012-07-30. PMID:21780181. |
to fill this gap, this study used methamphetamine (meth)-induced cpp in rats to ascertain if receptor changes occur in limbic brain regions that regulate drug-seeking, the medial prefrontal cortex (mpfc), nucleus accumbens (nac), and ventral pallidum (vp). |
2012-07-30 |
2023-08-12 |
rat |