| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shunsuke Tanahashi, Satoshi Yamamura, Masanori Nakagawa, Eishi Motomura, Motohiro Okad. Dopamine D2 and serotonin 5-HT1A receptors mediate the actions of aripiprazole in mesocortical and mesoaccumbens transmission. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:21925189. |
to address this, we examined the effects of systemic and local administrations of aripiprazole on extracellular levels of dopamine and gaba in medial prefrontal cortex (mpfc), nucleus accumbens (nac), and anterior (avta) and posterior (pvta) ventral tegmental areas. |
2012-07-27 |
2023-08-12 |
Not clear |
| Jennifer R St Onge, Colin M Stopper, Daniel S Zahm, Stan B Floresc. Separate prefrontal-subcortical circuits mediate different components of risk-based decision making. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 8. 2012-04-16. PMID:22357871. |
we used disconnection and neuroanatomical techniques to reveal that separate, yet interconnected, neural pathways linking the medial prefrontal cortex (pfc), the basolateral amygdala (bla), and nucleus accumbens (nac) contribute to these different decision biases in rats. |
2012-04-16 |
2023-08-12 |
rat |
| Arif Muhammad, Bryan Kol. Mild prenatal stress-modulated behavior and neuronal spine density without affecting amphetamine sensitization. Developmental neuroscience. vol 33. issue 2. 2012-04-02. PMID:21576912. |
moreover, ps increased the spine density in the nucleus accumbens (nac) and decreased it in the medial prefrontal cortex (mpfc) without any alteration in the orbital frontal cortex (ofc). |
2012-04-02 |
2023-08-12 |
rat |
| A R Burke, M J Watt, G L Forste. Adolescent social defeat increases adult amphetamine conditioned place preference and alters D2 dopamine receptor expression. Neuroscience. vol 197. 2012-02-27. PMID:21933700. |
we measured d1 and d2 dopamine receptor protein content in the medial prefrontal cortex, nucleus accumbens (nac), and dorsal striatum following either adolescent social defeat or foot-shock stress and then adult amphetamine cpp. |
2012-02-27 |
2023-08-12 |
human |
| Xiao Han, Weiwen Wang, Feng Shao, Nanxin L. Isolation rearing alters social behaviors and monoamine neurotransmission in the medial prefrontal cortex and nucleus accumbens of adult rats. Brain research. vol 1385. 2012-02-14. PMID:21338587. |
isolation-reared rats also manifested increased dopamine and serotonin levels in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) as well as an increase in serotonin turnover in the nac. |
2012-02-14 |
2023-08-12 |
rat |
| Xiao Han, Weiwen Wang, Xiaofang Xue, Feng Shao, Nanxin L. Brief social isolation in early adolescence affects reversal learning and forebrain BDNF expression in adult rats. Brain research bulletin. vol 86. issue 3-4. 2012-01-23. PMID:21801814. |
we also found that brain-derived neurotrophic factor (bdnf) protein expression was increased in the medial prefrontal cortex (mpfc) but was decreased in the nucleus accumbens (nac), ca1 and dentate gyrus of the hippocampus in isolation-reared rats. |
2012-01-23 |
2023-08-12 |
rat |
| David N George, Trisha A Jenkins, Simon Killcros. Dissociation of prefrontal cortex and nucleus accumbens dopaminergic systems in conditional learning in rats. Behavioural brain research. vol 225. issue 1. 2012-01-18. PMID:21741412. |
following training, microdialysis probes were implanted unilaterally in either the medial prefrontal cortex (mpfc) or nucleus accumbens (nac) and samples were collected in freely moving animals during a behavioural test session. |
2012-01-18 |
2023-08-12 |
rat |
| D Quarta, C P Leslie, R Carletti, E Valerio, L Caberlott. Central administration of NPY or an NPY-Y5 selective agonist increase in vivo extracellular monoamine levels in mesocorticolimbic projecting areas. Neuropharmacology. vol 60. issue 2-3. 2011-11-22. PMID:20868698. |
thus, the first aim of the present study was to investigate the distribution of npy-y5 receptor binding sites in rat mesocorticolimbic projection areas such as the nucleus accumbens (nac), medial prefrontal cortex (mpfc), and lateral hypothalamus (lh). |
2011-11-22 |
2023-08-12 |
rat |
| John J Byrnes, Erin D Gleason, Matthew K Schoen, Mathew T Schoen, Dennis F Lovelock, Lindsay M Carini, Elizabeth M Byrnes, Robert S Bridge. Accelerated maternal responding following intra-VTA pertussis toxin treatment. Behavioural brain research. vol 223. issue 2. 2011-10-24. PMID:21571006. |
accordingly, the ventral tegmental area (vta) and its dopaminergic projections to the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) have been implicated in both the onset and maintenance of normal maternal behavior. |
2011-10-24 |
2023-08-12 |
rat |
| Arif Muhammad, Bryan Kol. Maternal separation altered behavior and neuronal spine density without influencing amphetamine sensitization. Behavioural brain research. vol 223. issue 1. 2011-10-18. PMID:21515311. |
the spine density was examined in the nucleus accumbens (nac), the medial prefrontal cortex (mpfc), and the orbital frontal cortex (ofc) from golgi-cox stained neurons. |
2011-10-18 |
2023-08-12 |
rat |
| Richard J Beninger, Tyson W Baker, Matthew M Florczynski, Tomek J Banasikowsk. Regional differences in the action of antipsychotic drugs: implications for cognitive effects in schizophrenic patients. Neurotoxicity research. vol 18. issue 3-4. 2011-09-15. PMID:20376711. |
evidence from immediate early gene immunohistochemical, electrophysiological, microdialysis, imaging, and behavioral studies suggests that typical apds preferentially affect the nucleus accumbens (nac) and the dorsal striatum while atypical apds preferentially affect the nac and medial prefrontal cortex (pfc). |
2011-09-15 |
2023-08-12 |
Not clear |
| Garret D Stuber, Dennis R Sparta, Alice M Stamatakis, Wieke A van Leeuwen, Juanita E Hardjoprajitno, Saemi Cho, Kay M Tye, Kimberly A Kempadoo, Feng Zhang, Karl Deisseroth, Antonello Bonc. Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. Nature. vol 475. issue 7356. 2011-08-30. PMID:21716290. |
moreover, although optical stimulation of glutamatergic fibres from the medial prefrontal cortex to the nac also elicited reliable excitatory synaptic responses, optical self-stimulation behaviour was not observed by activation of this pathway. |
2011-08-30 |
2023-08-12 |
mouse |
| Stephan Lammel, Daniela I Ion, Jochen Roeper, Robert C Malenk. Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli. Neuron. vol 70. issue 5. 2011-08-23. PMID:21658580. |
administration of cocaine selectively modified excitatory synapses on da cells projecting to nucleus accumbens (nac) medial shell while an aversive stimulus selectively modified synapses on da cells projecting to medial prefrontal cortex. |
2011-08-23 |
2023-08-12 |
mouse |
| José Antonio Fuentealba, Katia Gysling, María Estela André. Repeated treatment with the κ-opioid agonist U-69593 increases K+-stimulated dopamine release in the rat medial prefrontal cortex. Synapse (New York, N.Y.). vol 64. issue 12. 2011-08-15. PMID:20939060. |
acute activation of κ-opioid receptors (kor) decreases dopamine (da) extracellular levels in both the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac). |
2011-08-15 |
2023-08-12 |
rat |
| L Pozzi, M Baviera, G Sacchetti, E Calcagno, C Balducci, R W Invernizzi, M Carl. Attention deficit induced by blockade of N-methyl D-aspartate receptors in the prefrontal cortex is associated with enhanced glutamate release and cAMP response element binding protein phosphorylation: role of metabotropic glutamate receptors 2/3. Neuroscience. vol 176. 2011-06-01. PMID:21193020. |
in parallel studies using microdialysis technique and western blot analysis we found that (r)-cpp (100 μm) infused in the medial prefrontal cortex increased glutamate efflux whereas injected in the medial prefrontal cortex at a dose causing impairments in attentional performance (50 ng/side) increased p-s(133)creb in the frontal cortex (fc), decreased it in the caudate-putamen (cpu) and was without effect in the nucleus accumbens (nac). |
2011-06-01 |
2023-08-12 |
rat |
| A J D Nelson, K E Thur, C A Marsden, H J Cassada. Catecholaminergic depletion within the prelimbic medial prefrontal cortex enhances latent inhibition. Neuroscience. vol 170. issue 1. 2011-05-24. PMID:20619321. |
previous work has suggested that lesions to the medial prefrontal cortex (mpfc), another major source of input to the nac, do not disrupt li. |
2011-05-24 |
2023-08-12 |
Not clear |
| Mercè Masana, Analía Bortolozzi, Francesc Artiga. Selective enhancement of mesocortical dopaminergic transmission by noradrenergic drugs: therapeutic opportunities in schizophrenia. The international journal of neuropsychopharmacology. vol 14. issue 1. 2011-05-24. PMID:20701825. |
given that noradrenergic (ne) transmission contributes to cortical da output, we assessed the ability of ne-targeting drugs to modulate da release in medial prefrontal cortex (mpfc) and nucleus accumbens (nac), with the aim of selectively increasing mesocortical da. |
2011-05-24 |
2023-08-12 |
rat |
| Charlotte Wiker, Love Linnér, Marie-Louise Wadenberg, Torgny H Svensso. Adjunctive treatment with mianserin enhances effects of raclopride on cortical dopamine output and, in parallel, its antipsychotic-like effect. Neuropsychiatric disease and treatment. vol 1. issue 3. 2011-05-17. PMID:18568103. |
here, we have examined the effect of mianserin in combination with the selective dopamine (da) d(2/3) receptor antagonist raclopride on conditioned avoidance response (car), a preclinical test of antipsychotic efficacy with high predictive validity; catalepsy, a preclinical test of extrapyramidal side effect liability; and da output in the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), respectively. |
2011-05-17 |
2023-08-12 |
rat |
| V Valentini, R Frau, F Bordi, F Borsini, G Di Chiar. A microdialysis study of ST1936, a novel 5-HT6 receptor agonist. Neuropharmacology. vol 60. issue 4. 2011-05-12. PMID:21185318. |
here we report the effect of st1936 (5-10-20 mg/kg/ip) on dialysate da, na and 5-ht in the medial prefrontal cortex (pfcx) and in the shell and core of the nucleus accumbens (nac). |
2011-05-12 |
2023-08-12 |
Not clear |
| Charlotte Wiker, Love Linnér, Marie-Louise Wadenberg, Torgny H Svensso. Adjunctive treatment with mianserin enhances effects of raclopride on cortical dopamine output and, in parallel, its antipsychotic-like effect. Neuropsychiatric disease and treatment. vol 1. issue 4. 2011-04-06. PMID:18568117. |
here, we have examined the effect of mianserin in combination with the selective dopamine (da) d(2/3) receptor antagonist raclopride on conditioned avoidance response (car), a preclinical test of antipsychotic efficacy with high predictive validity; catalepsy, a preclinical test of extrapyramidal side effect liability; and da output in the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), respectively. |
2011-04-06 |
2023-08-12 |
rat |