| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chelsea A Vadnie, David J Hinton, Sun Choi, YuBin Choi, Christina L Ruby, Alfredo Oliveros, Miguel L Prieto, Jun Hyun Park, Doo-Sup Cho. Activation of neurotensin receptor type 1 attenuates locomotor activity. Neuropharmacology. vol 85. 2015-03-30. PMID:24929110. |
since the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) have been implicated in the behavioral effects of nt, we examined whether microinjection of pd149163 into these regions reduces locomotion. |
2015-03-30 |
2023-08-13 |
mouse |
| Fang-Chi Yang, K C Lian. Interactions of the dorsal hippocampus, medial prefrontal cortex and nucleus accumbens in formation of fear memory: difference in inhibitory avoidance learning and contextual fear conditioning. Neurobiology of learning and memory. vol 112. 2015-02-09. PMID:23891992. |
this study examined how the nuclus accumbens (nac), dorsal hippocampus (dh) and medial prefrontal cortex (mpfc) may interact in memory processing for these two kinds of responses. |
2015-02-09 |
2023-08-12 |
rat |
| Yao-Ying Ma, Brian R Lee, Xiusong Wang, Changyong Guo, Lei Liu, Ranji Cui, Yan Lan, Judith J Balcita-Pedicino, Marina E Wolf, Susan R Sesack, Yavin Shaham, Oliver M Schlüter, Yanhua H Huang, Yan Don. Bidirectional modulation of incubation of cocaine craving by silent synapse-based remodeling of prefrontal cortex to accumbens projections. Neuron. vol 83. issue 6. 2015-01-21. PMID:25199705. |
glutamatergic projections from the medial prefrontal cortex (mpfc) to nucleus accumbens (nac) contribute to cocaine relapse. |
2015-01-21 |
2023-08-13 |
rat |
| Mei-Yi Lee, Chun-Cheng Chiang, Hong-Yi Chiu, Ming-Huan Chan, Hwei-Hsien Che. N-acetylcysteine modulates hallucinogenic 5-HT(2A) receptor agonist-mediated responses: behavioral, molecular, and electrophysiological studies. Neuropharmacology. vol 81. 2014-12-15. PMID:24534112. |
nac significantly attenuated doi-induced head twitch response and expression of c-fos and egr-2 in the infralimbic and motor cortex and suppressed the increase in the frequency of excitatory field potentials elicited by doi in the medial prefrontal cortex. |
2014-12-15 |
2023-08-12 |
mouse |
| Danielle C Malkusz, Sonia Y Bernal, Theodore Banakos, Gina Malkusz, Andrew Mohamed, Tracy Vongwattanakit, Richard J Bodna. Evaluation of saccharin intake and expression of fructose-conditioned flavor preferences following opioid receptor antagonism in the medial prefrontal cortex, amygdala or lateral hypothalamus in rats. Neuroscience letters. vol 564. 2014-11-26. PMID:24560952. |
in contrast, fructose-conditioned flavor preferences (cfp) were reduced or eliminated by systemic or intracerebral administration of dopamine (da) d1 or d2 antagonists in the nac, medial prefrontal cortex (mpfc), amygdala (amy) or lateral hypothalamus (lh). |
2014-11-26 |
2023-08-12 |
rat |
| Natalie E Zlebnik, Valerie L Hedges, Marilyn E Carroll, Robert L Meise. Chronic wheel running affects cocaine-induced c-Fos expression in brain reward areas in rats. Behavioural brain research. vol 261. 2014-10-06. PMID:24342748. |
the c-fos transcription factor is a measure of cellular activity and was used to quantify cocaine-induced activation of reward-processing areas of the brain: nucleus accumbens (nac), caudate putamen (cpu), medial prefrontal cortex (mpfc), and orbitofrontal cortex (ofc). |
2014-10-06 |
2023-08-12 |
human |
| Lucia Caffino, Chiara Cassina, Giuseppe Giannotti, Alessandro Orrù, Federico Moro, Angelo Di Clemente, Giorgio Racagni, Fabio Fumagalli, Luigi Cerv. Short-term abstinence from cocaine self-administration, but not passive cocaine infusion, elevates αCaMKII autophosphorylation in the rat nucleus accumbens and medial prefrontal cortex. The international journal of neuropsychopharmacology. vol 17. issue 2. 2014-08-26. PMID:23953174. |
increased αcamkii autophosphorylation in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc), but not dorsolateral striatum (dls), was found 24 h, but not immediately, after the last cocaine self-administration session. |
2014-08-26 |
2023-08-12 |
rat |
| Neal R Swerdlow, Susan B Powell, Michelle R Breier, Samantha R Hines, Gregory A Ligh. Coupling of gene expression in medial prefrontal cortex and nucleus accumbens after neonatal ventral hippocampal lesions accompanies deficits in sensorimotor gating and auditory processing in rats. Neuropharmacology. vol 75. 2014-08-19. PMID:23810830. |
in intact rats, the regulation of ppi by the ventral hippocampus (vh) is mediated via interactions with medial prefrontal cortex (mpfc) and nucleus accumbens (nac). |
2014-08-19 |
2023-08-12 |
rat |
| Morris D Faiman, Swetha Kaul, Shaheen A Latif, Todd D Williams, Craig E Lunt. S-(N, N-diethylcarbamoyl)glutathione (carbamathione), a disulfiram metabolite and its effect on nucleus accumbens and prefrontal cortex dopamine, GABA, and glutamate: a microdialysis study. Neuropharmacology. vol 75. 2014-08-19. PMID:23891816. |
in the present studies, we employed microdialysis techniques to investigate the effect of carb administration on dopamine (da), gaba, and glutamate (glu) in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc), two brain regions implicated in substance abuse dependence. |
2014-08-19 |
2023-08-12 |
rat |
| Neal R Swerdlow, Gregory A Light, Ryan S Trim, Michelle R Breier, Samantha R Hines, Susan B Powel. Forebrain gene expression predicts deficits in sensorimotor gating after isolation rearing in male rats. Behavioural brain research. vol 257. 2014-06-25. PMID:24076151. |
ppi is normally regulated by the medial prefrontal cortex (mpfc) and nucleus accumbens (nac). |
2014-06-25 |
2023-08-12 |
rat |
| Alan L Pehrson, Thomas Cremers, Cecile Bétry, Marieke G C van der Hart, Laerke Jørgensen, Mathias Madsen, Nasser Haddjeri, Bjarke Ebert, Connie Sanche. Lu AA21004, a novel multimodal antidepressant, produces regionally selective increases of multiple neurotransmitters--a rat microdialysis and electrophysiology study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 2. 2014-04-21. PMID:22612991. |
extracellular 5-ht, ne and da levels were evaluated in the ventral hippocampus (vhc), medial prefrontal cortex (mpfc) and nucleus accumbens (nac) after acute and subchronic treatment with lu aa21004 or escitalopram. |
2014-04-21 |
2023-08-12 |
rat |
| Maria A De Luc. Habituation of the responsiveness of mesolimbic and mesocortical dopamine transmission to taste stimuli. Frontiers in integrative neuroscience. vol 8. 2014-04-09. PMID:24624065. |
the presentation of novel, remarkable, and unpredictable tastes increases dopamine (da) transmission in different da terminal areas such as the nucleus accumbens (nac) shell and core and the medial prefrontal cortex (mpfc), as estimated by in vivo microdialysis studies in rats. |
2014-04-09 |
2023-08-12 |
rat |
| R Mychasiuk, A Muhammad, C Carroll, B Kol. Does prenatal nicotine exposure alter the brain's response to nicotine in adolescence? A neuroanatomical analysis. The European journal of neuroscience. vol 38. issue 4. 2014-02-19. PMID:23679187. |
this study examined changes in dendritic morphology and spine density in multiple brain regions [zilles' areas: (i) the cg3 region of the anterior cingulate cortex or the medial prefrontal cortex, layer iii (cg3); (ii) the dorsal agranular insular cortex, layer iii (aid); (iii) the par i region of the parietal cortex, layer iii (par1) and (iv) the nucleus accumbens (nac)]of long-evans rats following exposure to nicotine prenatally, in late adolescence, or both prenatally and in adolescence. |
2014-02-19 |
2023-08-12 |
rat |
| R A Chambers, J N McClintick, A M Sentir, S A Berg, M Runyan, K H Choi, H J Edenber. Cortical-striatal gene expression in neonatal hippocampal lesion (NVHL)-amplified cocaine sensitization. Genes, brain, and behavior. vol 12. issue 5. 2014-01-27. PMID:23682998. |
rat genome-wide microarrays containing >24 000 probesets were used to examine separate and co-occurring effects of nvhls and cocaine sensitization (15 mg/kg/day × 5 days) on gene expression within medial prefrontal cortex (mpfc), nucleus accumbens (nac), and caudate-putamen (capu). |
2014-01-27 |
2023-08-12 |
rat |
| Ricardo M Baltazar, Lique M Coolen, Ian C Web. Diurnal rhythms in neural activation in the mesolimbic reward system: critical role of the medial prefrontal cortex. The European journal of neuroscience. vol 38. issue 2. 2014-01-23. PMID:23617901. |
rhythmic expression of cfos was observed in the nucleus accumbens (nac) core and shell, in the medial prefrontal cortex (mpfc), and in th-ir and non-th-ir cells in the ventral tegmental area (vta), with peak expression during the late night and nadirs during the late day. |
2014-01-23 |
2023-08-12 |
rat |
| Mary Kay Lobo, Samir Zaman, Diane M Damez-Werno, Ja Wook Koo, Rosemary C Bagot, Jennifer A DiNieri, Alexandria Nugent, Eric Finkel, Dipesh Chaudhury, Ramesh Chandra, Efrain Riberio, Jacqui Rabkin, Ezekiell Mouzon, Roger Cachope, Joseph F Cheer, Ming-Hu Han, David M Dietz, David W Self, Yasmin L Hurd, Vincent Vialou, Eric J Nestle. ΔFosB induction in striatal medium spiny neuron subtypes in response to chronic pharmacological, emotional, and optogenetic stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 47. 2014-01-21. PMID:24259563. |
to explore the circuit-mediated induction of Δfosb in striatum, we use optogenetics to enhance activity in limbic brain regions that send synaptic inputs to nac; these regions include the ventral tegmental area and several glutamatergic afferent regions: medial prefrontal cortex, amygdala, and ventral hippocampus. |
2014-01-21 |
2023-08-12 |
mouse |
| Man Li, Xiaofang Xue, Shuang Shao, Feng Shao, Weiwen Wan. Cognitive, emotional and neurochemical effects of repeated maternal separation in adolescent rats. Brain research. vol 1518. 2014-01-07. PMID:23623774. |
previous studies have reported that ms affected prepulse inhibition (ppi), anxiety-related behaviors, dopaminergic and serotonergic activity in adult rats, and in the present study, we investigated the effects of repeated (4h/day) maternal separation during postnatal days 1-21 on ppi and anxiety-related behaviors in an elevated plus maze, as well as dopamine d2 receptor (drd2) and 5-ht1a receptor expression in the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and hippocampus in adolescent rats. |
2014-01-07 |
2023-08-12 |
rat |
| Lucas Albrechet-Souza, Milene Cristina Carvalho, Marcus Lira Brandã. D(1)-like receptors in the nucleus accumbens shell regulate the expression of contextual fear conditioning and activity of the anterior cingulate cortex in rats. The international journal of neuropsychopharmacology. vol 16. issue 5. 2014-01-03. PMID:22964037. |
in fact, projection areas of the ventral tegmental area, such as the amygdala and hippocampus, are well established to be involved in the acquisition and expression of fear conditioning, while less is known about the role of the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) in these processes. |
2014-01-03 |
2023-08-12 |
rat |
| Fabio Fumagalli, Federico Moro, Lucia Caffino, Alessandro Orrù, Chiara Cassina, Giuseppe Giannotti, Angelo Di Clemente, Giorgio Racagni, Marco A Riva, Luigi Cerv. Region-specific effects on BDNF expression after contingent or non-contingent cocaine i.v. self-administration in rats. The international journal of neuropsychopharmacology. vol 16. issue 4. 2013-12-27. PMID:23164369. |
brain-derived neurotrophic factor (bdnf) dynamic changes were investigated in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) during use and the early phases of cocaine abstinence after 14 sessions (2 h self-administration/d; 0.25 mg/0.1 ml.6 s infusion) by employing a 'yoked control-operant paradigm'. |
2013-12-27 |
2023-08-12 |
rat |
| Andrew C Meyer, Nichole M Neugebauer, Guangrong Zheng, Peter A Crooks, Linda P Dwoskin, Michael T Bard. Effects of VMAT2 inhibitors lobeline and GZ-793A on methamphetamine-induced changes in dopamine release, metabolism and synthesis in vivo. Journal of neurochemistry. vol 127. issue 2. 2013-12-02. PMID:23875705. |
the effect of gz-793a (15 mg/kg) on da synthesis in tissue also was investigated in nac, striatum, medial prefrontal cortex and orbitofrontal cortex. |
2013-12-02 |
2023-08-12 |
rat |