All Relations between nac and medial prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
M Bendre, E Comasco, I Nylander, K W Nilsso. Effect of voluntary alcohol consumption on Maoa expression in the mesocorticolimbic brain of adult male rats previously exposed to prolonged maternal separation. Translational psychiatry. vol 5. 2016-07-19. PMID:26645625. transcript levels of maoa were assessed in the ventral tegmental area, nucleus accumbens (nac), medial prefrontal cortex, cingulate cortex, amygdala and dorsal striatum (ds). 2016-07-19 2023-08-13 human
b' C\\xc3\\xa9sar Quiroz, Marco Orr\\xc3\\xba, William Rea, Andr\\xc3\\xa9s Ciudad-Roberts, Gabriel Yepes, Jonathan P Britt, Sergi Ferr\\xc3\\xa. Local Control of Extracellular Dopamine Levels in the Medial Nucleus Accumbens by a Glutamatergic Projection from the Infralimbic Cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 3. 2016-05-27. PMID:26791215.' it is generally assumed that infralimbic cortex (ilc) and prelimbic cortex, two adjacent areas of the medial prefrontal cortex (mpfc) in rodents, provide selective excitatory glutamatergic inputs to the nucleus accumbens (nac) shell and core, respectively. 2016-05-27 2023-08-13 Not clear
A Harker, S Raza, K Williamson, B Kolb, R Gib. Preconception paternal stress in rats alters dendritic morphology and connectivity in the brain of developing male and female offspring. Neuroscience. vol 303. 2016-05-06. PMID:26149350. the purpose of this study was to examine the effect of preconception paternal stress on developing male and female offspring brain morphology in five brain areas; medial prefrontal cortex (mpfc), orbitofrontal cortex (ofc), parietal cortex (par1), hippocampus (ca1) and nucleus accumbens (nac). 2016-05-06 2023-08-13 rat
Justin R Yates, Mahesh Darna, Cassandra D Gipson, Linda P Dwoskin, Michael T Bard. Dissociable roles of dopamine and serotonin transporter function in a rat model of negative urgency. Behavioural brain research. vol 291. 2016-03-28. PMID:26005123. upon completion of behavioral training, vmax and km were obtained from kinetic analysis of [(3)h]da and [(3)h]5-ht uptake using synaptosomes prepared from nucleus accumbens (nac), dorsal striatum (str), medial prefrontal cortex (mpfc), and orbitofrontal cortex (ofc) isolated from individual rats. 2016-03-28 2023-08-13 rat
Yu-Wei Chen, Kimberly A Fiscella, Samuel Z Bacharach, Gianluigi Tanda, Yavin Shaham, Donna J Cal. Effect of yohimbine on reinstatement of operant responding in rats is dependent on cue contingency but not food reward history. Addiction biology. vol 20. issue 4. 2016-02-29. PMID:25065697. we also used in vivo microdialysis to determine yohimbine's effect on dopamine levels in nucleus accumbens (nac) and medial prefrontal cortex (mpfc). 2016-02-29 2023-08-13 rat
Malte Feja, Michael Koc. Frontostriatal systems comprising connections between ventral medial prefrontal cortex and nucleus accumbens subregions differentially regulate motor impulse control in rats. Psychopharmacology. vol 232. issue 7. 2016-02-29. PMID:25308377. the ventral medial prefrontal cortex (vmpfc) and the nucleus accumbens (nac) are key substrates of impulse control in rats. 2016-02-29 2023-08-13 rat
Rosemary C Bagot, Eric M Parise, Catherine J Peña, Hong-Xing Zhang, Ian Maze, Dipesh Chaudhury, Brianna Persaud, Roger Cachope, Carlos A Bolaños-Guzmán, Joseph F Cheer, Joseph Cheer, Karl Deisseroth, Ming-Hu Han, Eric J Nestle. Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression. Nature communications. vol 6. 2016-02-29. PMID:25952660. the nac receives glutamatergic inputs from the medial prefrontal cortex (mpfc), ventral hippocampus (vhip) and basolateral amygdala (amy). 2016-02-29 2023-08-13 mouse
Mohammad-Reza Zarrindast, Fatemeh Khakpa. The Modulatory Role of Dopamine in Anxiety-like Behavior. Archives of Iranian medicine. vol 18. issue 9. 2016-02-01. PMID:26317601. the activity of dopaminergic system is modulated by several neurotransmitters, including glutamatergic neurons from the medial prefrontal cortex (mpfc), gabaergic fibers from the nucleus accumbens (nac) as well as the ventral pallidum and cholinergic fibers from the pedunculopontine nucleus and the laterodorsal tegmental nucleus. 2016-02-01 2023-08-13 Not clear
Xiusong Wang, Lei Liu, Wendy Adams, Shouxin Li, Qian Zhang, Bingjin Li, Min Wang, Ranji Cu. Cocaine exposure alters dopaminergic modulation of prefronto-accumbens transmission. Physiology & behavior. vol 145. 2016-01-04. PMID:25839095. here, combining cocaine self-administration and in vivo extracellular recordings in anesthetized rats, we show that dopamine efflux in the nac evoked by electrically stimulating the ventral tegmental area (vta) exerted timing-dependent regulation of the excitatory accumbens response to stimulation of the medial prefrontal cortex (mpfc), and also that this modulation was blunted following prolonged abstinence from cocaine self-administration. 2016-01-04 2023-08-13 rat
Zheng-Ming Ding, Cynthia M Ingraham, Zachary A Rodd, William J McBrid. The reinforcing effects of ethanol within the posterior ventral tegmental area depend on dopamine neurotransmission to forebrain cortico-limbic systems. Addiction biology. vol 20. issue 3. 2016-01-01. PMID:24674134. intra-pvta microinjection of ethanol increases dopamine release in the nucleus accumbens (nac), medial prefrontal cortex (mpfc) and ventral pallidum (vp). 2016-01-01 2023-08-12 Not clear
P A Pereira, M Vilela, S Sousa, J Neves, M M Paula-Barbosa, M D Madeir. Lesions of the laterodorsal tegmental nucleus alter the cholinergic innervation and neuropeptide Y expression in the medial prefrontal cortex and nucleus accumbens. Neuroscience. vol 284. 2015-12-30. PMID:25451286. the effects of this manipulation were determined in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) by estimating the numerical density of varicosities immunoreactive for vesicular acetylcholine transporter and the total number of nac neurons immunoreactive for choline acetyltransferase (chat) and neuropeptide y (npy) as well as the total number of mpfc neurons immunoreactive for npy and vasoactive intestinal polypeptide (vip). 2015-12-30 2023-08-13 rat
Angélica P Escobar, Francisca A Cornejo, Montserrat Olivares-Costa, Marcela González, José A Fuentealba, Katia Gysling, Rodrigo A España, María E André. Reduced dopamine and glutamate neurotransmission in the nucleus accumbens of quinpirole-sensitized rats hints at inhibitory D2 autoreceptor function. Journal of neurochemistry. vol 134. issue 6. 2015-12-14. PMID:26112331. moreover, the increase in nac glutamate release induced by direct stimulation of medial prefrontal cortex was significantly lower in qnp-sensitized rats. 2015-12-14 2023-08-13 rat
Angélica P Escobar, Francisca A Cornejo, Montserrat Olivares-Costa, Marcela González, José A Fuentealba, Katia Gysling, Rodrigo A España, María E André. Reduced dopamine and glutamate neurotransmission in the nucleus accumbens of quinpirole-sensitized rats hints at inhibitory D2 autoreceptor function. Journal of neurochemistry. vol 134. issue 6. 2015-12-14. PMID:26112331. together, these results indicate that repeated activation of d2 receptors disconnects nac from medial prefrontal cortex and ventral tegmental area. 2015-12-14 2023-08-13 rat
Robert D Winefield, Anthonius A M Heemskerk, Swetha Kaul, Todd D Williams, Michael J Caspers, Thomas E Prisinzano, Elinore F McCance-Katz, Craig E Lunte, Morris D Faima. N-acetyl-S-(N,N-diethylcarbamoyl) cysteine in rat nucleus accumbens, medial prefrontal cortex, and in rat and human plasma after disulfiram administration. Journal of pharmaceutical and biomedical analysis. vol 107. 2015-12-01. PMID:25720821. employing microdialysis sampling, detc-nac levels in the nucleus accumbens (nac), medial prefrontal cortex (mpfc), and plasma of rats treated with dsf reached 1.1, 2.5 and 80 nm at 6h. 2015-12-01 2023-08-13 human
J A D Dela Cruz, T Coke, T Karagiorgis, C Sampson, D Icaza-Cukali, K Kest, R Ranaldi, R J Bodna. c-Fos induction in mesotelencephalic dopamine pathway projection targets and dorsal striatum following oral intake of sugars and fats in rats. Brain research bulletin. vol 111. 2015-10-22. PMID:25460109. dopamine (da) signaling in the medial prefrontal cortex (mpfc), the amygdala (amy) and the nucleus accumbens (nac), has been implicated in acquisition and expression of fat- and sugar-cfp. 2015-10-22 2023-08-13 rat
Qiong Wang, Feng Shao, Weiwen Wan. Maternal separation produces alterations of forebrain brain-derived neurotrophic factor expression in differently aged rats. Frontiers in molecular neuroscience. vol 8. 2015-09-21. PMID:26388728. in this study, we investigated the effects of repeated ms (4 h per day from postnatal day (pnd) 1-21) on the brain-derived neurotrophic factor (bdnf) expression in the medial prefrontal cortex (mpfc), the nucleus accumbens (nac) and the hippocampus of male and female juvenile (pnd 21), adolescent (pnd 35) and young adult (pnd 56) wistar rats. 2015-09-21 2023-08-13 rat
Katherine N Wright, Fiona Hollis, Florian Duclot, Amanda M Dossat, Caroline E Strong, T Chase Francis, Roger Mercer, Jian Feng, David M Dietz, Mary Kay Lobo, Eric J Nestler, Mohamed Kabba. Methyl supplementation attenuates cocaine-seeking behaviors and cocaine-induced c-Fos activation in a DNA methylation-dependent manner. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 23. 2015-08-19. PMID:26063926. furthermore, upregulation of dna methyltransferase 3a and 3b and global dna hypomethylation were observed in the nucleus accumbens core (nac), but not in the medial prefrontal cortex (mpfc), of cocaine-pretreated rats. 2015-08-19 2023-08-13 human
Betina González, Mariana Raineri, Jean Lud Cadet, Edgar García-Rill, Francisco J Urbano, Veronica Bisagn. Modafinil improves methamphetamine-induced object recognition deficits and restores prefrontal cortex ERK signaling in mice. Neuropharmacology. vol 87. 2015-08-04. PMID:24530829. we also measured extracellular signal-regulated kinase (erk) phosphorylation in medial prefrontal cortex (mpfc), hippocampus, and nucleus accumbens (nac) of meth- and vehicle-treated mice that received modafinil 1 h before exposure to novel objects in the training session, compared to mice placed in the arena without objects. 2015-08-04 2023-08-12 mouse
Mesbah Alam, Svilen Angelov, Meike Stemmler, Christof von Wrangel, Joachim K Krauss, Kerstin Schwab. Neuronal activity of the prefrontal cortex is reduced in rats selectively bred for deficient sensorimotor gating. Progress in neuro-psychopharmacology & biological psychiatry. vol 56. 2015-07-31. PMID:25220677. little is known about neuronal activity in the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), which are involved in the modulation of ppi. 2015-07-31 2023-08-13 rat
Elena Martín-García, Julien Courtin, Prisca Renault, Jean-François Fiancette, Hélène Wurtz, Amélie Simonnet, Florian Levet, Cyril Herry, Véronique Deroche-Gamone. Frequency of cocaine self-administration influences drug seeking in the rat: optogenetic evidence for a role of the prelimbic cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 10. 2015-04-15. PMID:24633559. the medial prefrontal cortex (mpfc), basolateral amygdala (bla), and nucleus accumbens (nac) have been shown to have a role in cocaine seeking. 2015-04-15 2023-08-12 human