| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xixi Yang, Yichong Wen, Yuxiang Zhang, Feifei Gao, Jingsi Yang, Zhuojin Yang, Chunxia Ya. Dynamic Changes of Cytoskeleton-Related Proteins Within Reward-Related Brain Regions in Morphine-Associated Memory. Frontiers in neuroscience. vol 14. 2021-02-16. PMID:33584180. |
compared with the nac and dorsal hippocampus, dynamic changes in the medial prefrontal cortex (mpfc) and caudate putamen (cpu) were not very significant. |
2021-02-16 |
2023-08-13 |
mouse |
| Mei Huang, Wenqi He, Lakshmi Rajagopal, Andrea Kudwa, Dimitri E Grigoriadis, Herbert Y Meltze. Effects of NBI-98782, a selective vesicular monoamine transporter 2 (VMAT2) inhibitor, on neurotransmitter efflux and phencyclidine-induced locomotor activity: Relevance to tardive dyskinesia and antipsychotic action. Pharmacology, biochemistry, and behavior. vol 190. 2021-01-07. PMID:32084491. |
we utilized microdialysis in awake, freely moving mice to determine the effect of nbi-98782, the active metabolite of valbenazine, alone, or in combination with several antipsychotic drugs (apds), to influence neurotransmitter efflux in the medial prefrontal cortex (mpfc), dorsal striatum (dstr), hippocampus and nucleus accumbens (nac); we also compared it with tetrabenazine, the prototypical vmat2 inhibitor. |
2021-01-07 |
2023-08-13 |
mouse |
| Patricia Barra de la Tremblaye, Nicolas Narvaez Linares, Sarah Schock, Hélène Plamondo. Activation of CRHR1 receptors regulates social and depressive-like behaviors and expression of BDNF and TrkB in mesocorticolimbic regions following global cerebral ischemia. Experimental neurology. vol 284. issue Pt A. 2021-01-05. PMID:27498336. |
immunohistochemistry, western blot and rt-pcr were used to assess bdnf and trkb receptor levels in subregions of the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and ventral tegmental area (vta) 30days post-ischemia. |
2021-01-05 |
2023-08-13 |
rat |
| Katelyn L Low, Ryan J Tomm, Chunqi Ma, Daniel J Tobiansky, Stan B Floresco, Kiran K Som. Effects of aging on testosterone and androgen receptors in the mesocorticolimbic system of male rats. Hormones and behavior. vol 120. 2020-12-21. PMID:31954104. |
here, we examined young adult (5 months) and aged (22 months) male fischer 344 × brown norway rats, and measured systemic t levels in serum and local t levels in microdissected nodes of the mesocorticolimbic system (ventral tegmental area (vta), nucleus accumbens (nac), medial prefrontal cortex (mpfc), and orbitofrontal cortex (ofc)). |
2020-12-21 |
2023-08-13 |
rat |
| Jeff Boissoneault, Bethany Stennett, Michael E Robinso. Acute alcohol intake alters resting state functional connectivity of nucleus accumbens with pain-related corticolimbic structures. Drug and alcohol dependence. vol 207. 2020-11-23. PMID:31891860. |
the nucleus accumbens (nac) is a ventral striatal structure underlying reward, reinforcement, and motivation, with extensive anatomic and functional connections to a wide range of affective processing structures (medial prefrontal cortex (mpfc), amygdala, and insula). |
2020-11-23 |
2023-08-13 |
Not clear |
| Wenbo Zhao, Ying Hu, Chuangang Li, Ning Li, Shaowei Zhu, Xu Tan, Meng Li, Yue Zhang, Zheng Xu, Zhaoxi Ding, Lingming Hu, Zengxun Liu, Jinhao Su. Transplantation of fecal microbiota from patients with alcoholism induces anxiety/depression behaviors and decreases brain mGluR1/PKC ε levels in mouse. BioFactors (Oxford, England). vol 46. issue 1. 2020-11-19. PMID:31518024. |
then we evaluated their alcohol preference degree, anxiety, and depression-like behaviors and social interaction behaviors, together with molecular changes in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac). |
2020-11-19 |
2023-08-13 |
mouse |
| Qingxiao Hong, Jing Liu, Zi Lin, Dingding Zhuang, Wenjin Xu, Zemin Xu, Miaojun Lai, Huaqiang Zhu, Wenhua Zhou, Huifen Li. Histone 3 lysine 9 acetylation of BRG1 in the medial prefrontal cortex is associated with heroin self‑administration in rats. Molecular medicine reports. vol 21. issue 1. 2020-11-06. PMID:31939625. |
chromatin immunoprecipitation followed by reverse transcription‑quantitative pcr (rt‑qpcr) was used to detect the accumulation of h3k9ac on brg1 in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) following heroin self‑administration. |
2020-11-06 |
2023-08-13 |
rat |
| Gerdien A H Korte-Bouws, Floor van Heesch, Koen G C Westphal, Lisa M J Ankersmit, Edwin M van Oosten, Onur Güntürkün, S Mechiel Kort. Bacterial Lipopolysaccharide Increases Serotonin Metabolism in Both Medial Prefrontal Cortex and Nucleus Accumbens in Male Wild Type Rats, but Not in Serotonin Transporter Knockout Rats. Pharmaceuticals (Basel, Switzerland). vol 11. issue 3. 2020-10-01. PMID:29976854. |
administered lps increased extracellular monoamine metabolite levels in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc), which was completely, or at least partly, prevented by pretreatment with a triple reuptake inhibitor that also blocks the serotonin (5-ht) transporter (sert). |
2020-10-01 |
2023-08-13 |
rat |
| Liang Qu, Yuan Wang, Shun-Nan Ge, Nan Li, Jian Fu, Yue Zhang, Xin Wang, Jiang-Peng Jing, Yang Li, Qiang Wang, Guo-Dong Gao, Shi-Ming He, Xue-Lian Wan. Altered Activity of SK Channel Underpins Morphine Withdrawal Relevant Psychiatric Deficiency in Infralimbic to Accumbens Shell Pathway. Frontiers in psychiatry. vol 10. 2020-10-01. PMID:31031665. |
the nucleus accumbens (nac) plays a crucial role in regulating craving and relapse, while the medial prefrontal cortex (mpfc) represents a higher cortex projecting into the nac that is active in the management of executive function. |
2020-10-01 |
2023-08-13 |
Not clear |
| Pu-Chao Zhuang, Zhi-Nei Tan, Zi-Yan Jia, Biju Wang, James J Grady, Xin-Ming M. Treadmill Exercise Reverses Depression Model-Induced Alteration of Dendritic Spines in the Brain Areas of Mood Circuit. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31130853. |
the aim of this study was to determine whether treadmill exercise reverses cums-induced both depression-like behaviors and alterations in spine density and morphology of the principal neurons in the brain areas of the mood circuits including the hippocampus, medial prefrontal cortex (mpfc), nucleus accumbens (nac) and basolateral amygdala (bla). |
2020-10-01 |
2023-08-13 |
rat |
| Javier A Muñiz, José P Prieto, Betina González, Máximo H Sosa, Jean L Cadet, Cecilia Scorza, Francisco J Urbano, Verónica Bisagn. Cocaine and Caffeine Effects on the Conditioned Place Preference Test: Concomitant Changes on Early Genes within the Mouse Prefrontal Cortex and Nucleus Accumbens. Frontiers in behavioral neuroscience. vol 11. 2020-09-30. PMID:29093669. |
the goal of the present study was thus to determine caffeine and cocaine combined effects on the conditioned place preference (cpp) test and to determine potential differential mrna expression in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) of immediate-early genes (iegs) as well as dopamine and adenosine receptor subunits. |
2020-09-30 |
2023-08-13 |
mouse |
| Yan Xiao, Huoqing Luo, Wen Z Yang, Yeting Zeng, Yinbo Shen, Xinyan Ni, Zhaomei Shi, Jun Zhong, Ziqi Liang, Xiaoyu Fu, Hongqing Tu, Wenzhi Sun, Wei L Shen, Ji Hu, Jiajun Yan. A Brain Signaling Framework for Stress-Induced Depression and Ketamine Treatment Elucidated by Phosphoproteomics. Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32317933. |
we analyzed the phosphoprotein changes induced by chronic unpredictable mild stress (cums) and ketamine treatment in two known mood control centers, the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac). |
2020-09-28 |
2023-08-13 |
mouse |
| Erik J Garcia, David L Arndt, Mary E Cai. Dynamic interactions of ceftriaxone and environmental variables suppress amphetamine seeking. Brain research. vol 1712. 2020-09-11. PMID:30716289. |
we hypothesized that ec rearing would reduce reinstatement by altering glt1 or xct expression in the nac and medial prefrontal cortex (mpfc). |
2020-09-11 |
2023-08-13 |
rat |
| Carles Tapias-Espinosa, Cristóbal Río-Álamos, Ana Sánchez-González, Ignasi Oliveras, Daniel Sampedro-Viana, Maria Del Mar Castillo-Ruiz, Toni Cañete, Adolf Tobeña, Alberto Fernández-Terue. Schizophrenia-like reduced sensorimotor gating in intact inbred and outbred rats is associated with decreased medial prefrontal cortex activity and volume. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 11. 2020-07-06. PMID:30986819. |
relevant structures of the cspt circuit were evaluated, such as the medial prefrontal cortex (mpfc), cingulate cortex, hippocampus (hpc), amygdala, nucleus accumbens (nac), and dorsal striatum. |
2020-07-06 |
2023-08-13 |
rat |
| Laura Domingo-Rodriguez, Inigo Ruiz de Azua, Eduardo Dominguez, Eric Senabre, Irene Serra, Sami Kummer, Mohit Navandar, Sarah Baddenhausen, Clementine Hofmann, Raul Andero, Susanne Gerber, Marta Navarrete, Mara Dierssen, Beat Lutz, Elena Martín-García, Rafael Maldonad. A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction. Nature communications. vol 11. issue 1. 2020-05-18. PMID:32034128. |
here, using a food addiction mouse model, we report that the lack of cannabinoid type-1 receptor in dorsal telencephalic glutamatergic neurons prevents the development of food addiction-like behavior, which is associated with enhanced synaptic excitatory transmission in the medial prefrontal cortex (mpfc) and in the nucleus accumbens (nac). |
2020-05-18 |
2023-08-13 |
mouse |
| He Li, Hong-Quan Wan, Hai-Jun Zhao, Shu-Xin Luan, Chun-Guo Zhan. Identification of candidate genes and miRNAs associated with neuropathic pain induced by spared nerve injury. International journal of molecular medicine. vol 44. issue 4. 2020-02-04. PMID:31432094. |
murine rna‑seq samples from three brain regions [nucleus accumbens, (nac); medial prefrontal cortex, (mpfc) and periaqueductal gray, (pag)]were compared between the spared nerve injury (sni) model and a sham surgery. |
2020-02-04 |
2023-08-13 |
Not clear |
| Fernando Castillo Díaz, Micaela A Hernandez, Tomas Capellá, Jorge H Medin. Dopamine Neurotransmission in the Ventral Tegmental Area Promotes Active Forgetting of Cocaine-Associated Memory. Molecular neurobiology. vol 56. issue 9. 2020-01-09. PMID:30739236. |
in contrast, d1r in the nac shell, medial prefrontal cortex, or amygdala appear not to participate in the maintenance of cocaine-associated memory. |
2020-01-09 |
2023-08-13 |
Not clear |
| Rachel A Hill, Szerenke Kiss Von Soly, Udani Ratnayake, Maren Klug, Michele D Binder, Anthony J Hannan, Maarten van den Buus. Long-term effects of combined neonatal and adolescent stress on brain-derived neurotrophic factor and dopamine receptor expression in the rat forebrain. Biochimica et biophysica acta. vol 1842. issue 11. 2019-11-20. PMID:25159716. |
at adulthood the medial prefrontal cortex (mpfc), caudate putamen (cpu) and nucleus accumbens (nac) were analysed by qpcr and western blot. |
2019-11-20 |
2023-08-13 |
rat |
| Daniel J Tobiansky, Kathryn G Wallin-Miller, Stan B Floresco, Ruth I Wood, Kiran K Som. Androgen Regulation of the Mesocorticolimbic System and Executive Function. Frontiers in endocrinology. vol 9. 2019-11-20. PMID:29922228. |
first, we briefly review the neuroanatomy of the mesocorticolimbic system, which mediates executive function, with a focus on the ventral tegmental area (vta), nucleus accumbens (nac), medial prefrontal cortex (mpfc), and orbitofrontal cortex (ofc). |
2019-11-20 |
2023-08-13 |
Not clear |
| Zade R Holloway, Timothy G Freels, Josiah F Comstock, Hunter G Nolen, Helen J Sable, Deranda B Leste. Comparing phasic dopamine dynamics in the striatum, nucleus accumbens, amygdala, and medial prefrontal cortex. Synapse (New York, N.Y.). 2019-11-20. PMID:30317673. |
dopamine regulates behaviors associated with action selection in the striatum, reward in the nucleus accumbens (nac), emotional processing in the amygdala, and executive functioning in the medial prefrontal cortex (mpfc). |
2019-11-20 |
2023-08-13 |
mouse |