| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michaela R Breach, Courtney N Dye, Anabel Galan, Kathryn M Len. Prenatal allergic inflammation in rats programs the developmental trajectory of dendritic spine patterning in brain regions associated with cognitive and social behavior. Brain, behavior, and immunity. 2022-03-04. PMID:35245680. |
mean dendritic spine density was calculated for neurons in brain regions associated with cognition and social behavior, including the medial prefrontal cortex (mpfc), basal ganglia, septum, nucleus accumbens (nac), and amygdala. |
2022-03-04 |
2023-08-13 |
rat |
| Rodolpho Pereira de Oliveira, José Simões de Andrade, Marianna Spina, João Vítor Chamon, Paulo Henrique Dias Silva, Ana Keyla Werder, Daniela Ortolani, Lucas de Santana Cardoso Thomaz, Simone Romariz, Daniel Araki Ribeiro, Beatriz Monteiro Longo, Regina Célia Spadari, Milena de Barros Viana, Liana Melo-Thomas, Isabel Cristina Céspedes, Regina Cláudia Barbosa da Silv. Clozapine prevented social interaction deficits and reduced c-Fos immunoreactivity expression in several brain areas of rats exposed to acute restraint stress. PloS one. vol 17. issue 3. 2022-03-03. PMID:35239670. |
in the present study, we evaluate the effect of acute restraint stress (15 min) of male wistar rats on social interaction measurements and c-fos immunoreactivity (c-fos-ir) expression, a marker of neuronal activity, in areas involved with the modulation of acute physical restraint in rats, i.e., the paraventricular nucleus of the hypothalamus (pvn), median raphe nucleus (mnr), medial prefrontal cortex (mpfc), cingulate prefrontal cortex (cpfc), nucleus accumbens (nac), hippocampus (ca3), lateral septum (ls) and medial amygdala (mea). |
2022-03-03 |
2023-08-13 |
rat |
| Matthew J Muelbl, Breanna L Glaeser, Alok S Shah, Rachel A Chiariello, Natalie N Nawarawong, Brian D Stemper, Matthew D Budde, Christopher M Olse. Repeated blast mild traumatic brain injury and oxycodone self-administration produce interactive effects on neuroimaging outcomes. Addiction biology. vol 27. issue 2. 2022-03-01. PMID:35229952. |
we found interactive effects of rbtbi and oxycodone on fractional anisotropy (fa) in the nucleus accumbens (nac) and that fa in the medial prefrontal cortex (mpfc) was correlated with drug seeking. |
2022-03-01 |
2023-08-13 |
rat |
| Ying Hao Yu, Yeou San Lim, Chen Yin Ou, Kai Chieh Chang, Arthur C Tsai, Fang Chih Chang, Andrew Chih Wei Huan. The Medial Prefrontal Cortex, Nucleus Accumbens, Basolateral Amygdala, and Hippocampus Regulate the Amelioration of Environmental Enrichment and Cue in Fear Behavior in the Animal Model of PTSD. Behavioural neurology. vol 2022. 2022-02-18. PMID:35178125. |
the present study addressed this issue and examined whether the medial prefrontal cortex (mpfc, including the cingulate cortex 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), the nucleus accumbens (nac), the basolateral amygdala (bla), and the hippocampus (e.g., ca1, ca3, and dentate gyrus (dg)) regulated the amelioration of the ee, cue, or the combination of ee and cue. |
2022-02-18 |
2023-08-13 |
Not clear |
| Kevin Clare, Chelsea Pan, Gloria Kim, Kicheon Park, Juan Zhao, Nora D Volkow, Zhicheng Lin, Congwu D. Cocaine Reduces the Neuronal Population While Upregulating Dopamine D2-Receptor-Expressing Neurons in Brain Reward Regions: Sex-Effects. Frontiers in pharmacology. vol 12. 2021-12-12. PMID:33912043. |
here, we investigated changes in the total neuronal density and relative concentration of d2r-expressing neurons in the medial prefrontal cortex (mpfc), dorsal striatum (dstr), nucleus accumbens (nac), and ventral tegmental area (vta) in both male and female mice passively exposed to cocaine for two weeks. |
2021-12-12 |
2023-08-13 |
mouse |
| Thilo Rusche, Jörn Kaufmann, Jürgen Voge. Nucleus accumbens projections: Validity and reliability of fiber reconstructions based on high-resolution diffusion-weighted MRI. Human brain mapping. vol 42. issue 18. 2021-12-03. PMID:34528323. |
for probabilistic fiber tracking the nac as a seed region and the medial prefrontal cortex (mpfc), anterior cingulate cortex (acc), amygdala (amy), hippocampus (hpc), dorsomedial thalamus (dmt) and ventral tegmental area (vta) as target regions were segmented for each subject and both hemispheres. |
2021-12-03 |
2023-08-13 |
human |
| Alexander K Zinsmaier, Yan Dong, Yanhua H Huan. Cocaine-induced projection-specific and cell type-specific adaptations in the nucleus accumbens. Molecular psychiatry. 2021-11-26. PMID:33963288. |
the nucleus accumbens (nac) integrates and prioritizes different emotional and motivational inputs to the reward system by processing convergent glutamatergic projections from the medial prefrontal cortex, basolateral amygdala, ventral hippocampus, and other limbic and paralimbic brain regions. |
2021-11-26 |
2023-08-13 |
Not clear |
| Kensuke Hirose, Yuka Nakaya, Kohei Kitano, Yasuhiko Saito, Ryosuke Kaneko, Yuchio Yanagawa, Kiyofumi Yamamoto, Tetsuo Shirakawa, Masayuki Kobayash. Differential regulation of medium spiny and cholinergic neurons in the nucleus accumbens core by the insular and medial prefrontal cortices in the rat. Pflugers Archiv : European journal of physiology. vol 473. issue 12. 2021-11-25. PMID:34724104. |
the nucleus accumbens (nac) receives cortical projections principally from the insular cortex (ic) and medial prefrontal cortex (mpfc). |
2021-11-25 |
2023-08-13 |
rat |
| Bai-Chuang Shyu, Zhi-Yue Gao, José Jiun-Shian Wu, Alan Bo Han He, Cai-N Cheng, Andrew Chih Wei Huan. Methamphetamine and Modulation Functionality of the Prelimbic Cortex for Developing a Possible Treatment of Alzheimer's Disease in an Animal Model. Frontiers in aging neuroscience. vol 13. 2021-11-10. PMID:34744692. |
this study examined whether a low dose of mamph can induce conditioned taste aversion (cta) learning, or can increase plasma corticosterone levels, neural activity, and neural plasticity in the medial prefrontal cortex (mpfc) (responsible for cognitive function), the nucleus accumbens (nac) and the amygdala (related to rewarding and aversive emotion), and the hippocampus (responsible for spatial learning). |
2021-11-10 |
2023-08-13 |
rat |
| Jessica Hayes, Bettina Laursen, Elin Eneberg, Jan Kehler, Lars Kyhn Rasmussen, Morten Langgard, Jesper F Bastlund, Todor V Gerdjiko. Phosphodiesterase type 1 inhibition alters medial prefrontal cortical activity during goal-driven behaviour and partially reverses neurophysiological deficits in the rat phencyclidine model of schizophrenia. Neuropharmacology. vol 186. 2021-11-05. PMID:33444639. |
to address this, we recorded single unit activity in medial prefrontal cortex (mpfc) and nucleus accumbens (nac) in lister hooded rats treated with the pde1b inhibitor lu af64386 and tested in the 5-choice serial reaction time task (5-csrtt). |
2021-11-05 |
2023-08-13 |
rat |
| Hashem Saberian, Afsaneh Asgari Taei, Anahita Torkaman-Boutorabi, Esmail Riahi, Samaneh Aminyavari, Ayeh Naghizadeh, Maryam Farahmandfa. Effect of histone acetylation on maintenance and reinstatement of morphine-induced conditioned place preference and ΔFosB expression in the nucleus accumbens and prefrontal cortex of male rats. Behavioural brain research. vol 414. 2021-11-04. PMID:34302880. |
h4 acetylation and Δfosb expression in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) were assessed on the last day of extinction and the following cpp reinstatement. |
2021-11-04 |
2023-08-13 |
rat |
| Zeinab Khastkhodaei, Muthuraman Muthuraman, Jenq-Wei Yang, Sergiu Groppa, Heiko J Luhman. Functional and directed connectivity of the cortico-limbic network in mice in vivo. Brain structure & function. vol 226. issue 3. 2021-11-02. PMID:33442810. |
central structures of this cortico-limbic network are ventral hippocampus (vhc), medial prefrontal cortex (pfc), basolateral amygdala (bla) and nucleus accumbens (nac). |
2021-11-02 |
2023-08-13 |
mouse |
| b' F Quessy, T Bittar, L J Blanchette, M L\\xc3\\xa9vesque, B Labont\\xc3\\xa. Stress-induced alterations of mesocortical and mesolimbic dopaminergic pathways. Scientific reports. vol 11. issue 1. 2021-10-29. PMID:34040100.' |
density of the mesolimbic and mesocortical projections was assessed via immuno-histochemistry combined with sholl analysis along with the staining of activity-dependent markers perk and c-fos in the ventral tegmental area (vta), nucleus accumbens (nac) and medial prefrontal cortex (mpfc). |
2021-10-29 |
2023-08-13 |
mouse |
| Barbara Ziółkowsk. The Role of Mesostriatal Dopamine System and Corticostriatal Glutamatergic Transmission in Chronic Pain. Brain sciences. vol 11. issue 10. 2021-10-26. PMID:34679376. |
the second part of this article focuses on the glutamatergic inputs from the medial prefrontal cortex to the nac, their activity changes in chronic pain, and their role in pain modulation. |
2021-10-26 |
2023-08-13 |
Not clear |
| Barbara Ziółkowsk. The Role of Mesostriatal Dopamine System and Corticostriatal Glutamatergic Transmission in Chronic Pain. Brain sciences. vol 11. issue 10. 2021-10-26. PMID:34679376. |
studies using novel techniques indicate that pain is regulated oppositely by two independent dopaminergic circuits linking separate parts of the ventral tegmental area and of the nac, which also interact with distinct regions of the medial prefrontal cortex. |
2021-10-26 |
2023-08-13 |
Not clear |
| Limeng Huang, Yiwen Chen, Sen Jin, Li Lin, Shumin Duan, Ke Si, Wei Gong, J Julius Zh. Organizational principles of amygdalar input-output neuronal circuits. Molecular psychiatry. 2021-10-06. PMID:34400771. |
using a simplified cell-type- and projection-specific retrograde transsynaptic tracing technique, we scrutinized brain-wide afferent inputs of four major output neuronal groups in the amygdalar basolateral complex (bla) that project to the bed nucleus of the stria terminals (bnst), ventral hippocampus (vhpc), medial prefrontal cortex (mpfc) and nucleus accumbens (nac), respectively. |
2021-10-06 |
2023-08-13 |
Not clear |
| Claudia Rangel-Barajas, Israel Coronel, Yanping Zhang, Maribel Hernández, Stephen L Boehm I. Low-level developmental lead exposure does not predispose to adult alcohol self-administration, but does increase the risk of relapsing to alcohol seeking in mice: Contrasting role of GLT1 and xCT brain expression. Neuropharmacology. vol 181. 2021-09-23. PMID:33010299. |
because pb exposure is associated with increased glutamatergic tone, we also studied the effects on the expression of synaptic and non-synaptic glutamate transporters in brain regions associated with drug addiction such as the nucleus accumbens (nac), dorsomedial striatum (dms), dorsolateral striatum (dls), and medial prefrontal cortex (mpfc). |
2021-09-23 |
2023-08-13 |
mouse |
| Jie Li, Chen Lu, Zilong Gao, Yifan Feng, Huoqing Luo, Tangsheng Lu, Xia Sun, Ji Hu, Yanli Lu. SNRIs achieve faster antidepressant effects than SSRIs by elevating the concentrations of dopamine in the forebrain. Neuropharmacology. vol 177. 2021-08-12. PMID:32710978. |
in our study, a genetically encoded dopamine sensor and in vivo fiber photometry recordings were used to measure the dopamine concentrations in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) after acute intraperitoneal injection of ssris or snris. |
2021-08-12 |
2023-08-13 |
Not clear |
| Jennaya Christensen, Glenn R Yamakawa, Sabrina Salberg, Melinda Wang, Bryan Kolb, Richelle Mychasiu. Caffeine consumption during development alters spine density and recovery from repetitive mild traumatic brain injury in young adult rats. Synapse (New York, N.Y.). vol 74. issue 4. 2021-08-10. PMID:31705690. |
both caffeine and rmtbi increased spine density in the cg3 (medial prefrontal cortex [mpfc]), aid (orbitofrontal cortex [ofc]), and nucleus accumbens (nac), which is proposed to reflect an impairment in the normal pruning processes. |
2021-08-10 |
2023-08-13 |
rat |
| b' Thibault P Bittar, Mari Carmen Pelaez, Jose Cesar Hernandez Silva, Francis Quessy, Andr\\xc3\\xa9e-Anne Lavigne, Daphn\\xc3\\xa9e Morency, L\\xc3\\xa9a-Jeanne Blanchette, Eric Arsenault, Yoan Cherasse, Jos\\xc3\\xa9e Seigneur, Igor Timofeev, Chantelle F Sephton, Christophe D Proulx, Benoit Labont\\xc3\\xa. Chronic Stress Induces Sex-Specific Functional and Morphological Alterations in Corticoaccumbal and Corticotegmental Pathways. Biological psychiatry. vol 90. issue 3. 2021-08-10. PMID:33867113.' |
the medial prefrontal cortex (mpfc) is part of a complex circuit controlling stress responses by sending projections to different limbic structures including the nucleus accumbens (nac) and ventral tegmental area (vta). |
2021-08-10 |
2023-08-13 |
Not clear |