| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michaël Loureiro, Ridouane Achargui, Jérôme Flakowski, Ruud Van Zessen, Thomas Stefanelli, Vincent Pascoli, Christian Lüsche. Social transmission of food safety depends on synaptic plasticity in the prefrontal cortex. Science (New York, N.Y.). vol 364. issue 6444. 2019-11-20. PMID:31171697. |
we detected enhanced activity after social transmission between two mice in neurons of the medial prefrontal cortex (mpfc) that target the nac and receive projections from the pic. |
2019-11-20 |
2023-08-13 |
mouse |
| Zengjian Wang, Jiliang Fang, Jun Liu, Peijing Rong, Kristen Jorgenson, Joel Park, Courtney Lang, Yang Hong, Bing Zhu, Jian Kon. Frequency-dependent functional connectivity of the nucleus accumbens during continuous transcutaneous vagus nerve stimulation in major depressive disorder. Journal of psychiatric research. vol 102. 2019-08-29. PMID:29674268. |
the results revealed: 1) significant positive fcs between the nac and surrounding areas including the putamen, caudate, and distinct areas of the medial prefrontal cortex (mpfc) and the anterior cingulate cortex (acc) during continuous real and sham tvns; 2) compared with sham tvns, real tvns increased the fc between the left nac and bilateral mpfc/racc in the slow-5 band (0.008-0.027) and between the right nac and left insula, occipital gyrus, and right lingual/fusiform gyrum in the typical low band (0.008-0.09); and 3) the fc of the nac-mpfc/racc during real tvns showed a negative association with hamilton depression rating scale (hamd) score changes in the real tvns group after one month of treatment, but not in the sham group. |
2019-08-29 |
2023-08-13 |
Not clear |
| Katsuyuki Kaneda, Satoshi Deyama, Eiichi Hinoi, Junko Yanagida, Tong Zhang, Hitoki Sasas. [Analyses of cocaine rewarding memories by AAV vector-induced introduction of DREADD system]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 153. issue 5. 2019-08-13. PMID:31092754. |
the development and persistence of drug addiction are associated with the activation and adaptation of the brain reward circuitry, which consists of dopaminergic projection from the ventral tegmental area to the nucleus accumbens (nac) and the medial prefrontal cortex (mpfc). |
2019-08-13 |
2023-08-13 |
mouse |
| Sanjeev K Bhardwaj, Fatéma Dodat, Daniel Lévesque, Lalit K Srivastav. Altered regulation of Nur77 nuclear receptor gene expression in the mesocorticolimbic regions of rat brain by amphetamine sensitization. Brain research. vol 1694. 2019-07-11. PMID:29750935. |
here we evaluated changes in nur77 mrna levels in the medial prefrontal cortex (mpfc), dorsal striatum (str) and nucleus accumbens (nac) of rats receiving a repeated, sensitizing regimen of amphetamine (amph). |
2019-07-11 |
2023-08-13 |
rat |
| Alaa M Hammad, Fawaz Alasmari, Youssef Sari, F Scott Hall, Amit K Tiwar. Alcohol and Cocaine Exposure Modulates ABCB1 and ABCG2 Transporters in Male Alcohol-Preferring Rats. Molecular neurobiology. vol 56. issue 3. 2019-07-01. PMID:29978425. |
in this study, we determined the effects of voluntary ethanol consumption following repeated exposure to cocaine or vehicle on the relative mrna and protein expression of abcg2/abcg2 and abcb1/abcb1 in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) of male alcohol-preferring (p) rats. |
2019-07-01 |
2023-08-13 |
rat |
| Daniel Knowland, Byung Kook Li. Circuit-based frameworks of depressive behaviors: The role of reward circuitry and beyond. Pharmacology, biochemistry, and behavior. vol 174. 2019-06-24. PMID:29309799. |
in particular, areas such as the ventral tegmental area (vta), nucleus accumbens (nac), and ventral pallidum (vp) are thought to generally promote reward, with the medial prefrontal cortex (mpfc) providing top-down control of reward seeking. |
2019-06-24 |
2023-08-13 |
Not clear |
| b' Przemys\\xc5\\x82aw Kowia\\xc5\\x84ski, Gra\\xc5\\xbcyna Lietzau, Aleksandra Steliga, Ewelina Czuba, Beata Ludkiewicz, Monika Wa\\xc5\\x9bkow, Jan H Spodnik, Janusz Mory\\xc5\\x9. Nicotine-induced CREB and DeltaFosB activity is modified by caffeine in the brain reward system of the rat. Journal of chemical neuroanatomy. vol 88. 2019-05-14. PMID:29100904.' |
we aimed at determining the effect of caffeine and nicotine, applied separately or simultaneously, on activation of six structures of the brain reward system: nucleus accumbens (nac), ventral tegmental area (vta), amygdala (amg), hippocampus (hip), medial prefrontal cortex (mpfr) and dorsal striatum (cdp) in the adult male wistar rats. |
2019-05-14 |
2023-08-13 |
rat |
| Paul Klauser, Lijing Xin, Margot Fournier, Alessandra Griffa, Martine Cleusix, Raoul Jenni, Michel Cuenod, Rolf Gruetter, Patric Hagmann, Philippe Conus, Philipp S Baumann, Kim Q D. N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial. Translational psychiatry. vol 8. issue 1. 2019-04-01. PMID:30315150. |
nac also led to a 23% increase in gsh levels in the medial prefrontal cortex (gsh |
2019-04-01 |
2023-08-13 |
Not clear |
| Di Liu, Qian-Qian Tang, Cui Yin, Yu Song, Yan Liu, Jun-Xia Yang, He Liu, Yue-Man Zhang, Si-Yin Wu, Ying Song, Barbara Juarez, Hai-Lei Ding, Ming-Hu Han, Hongxing Zhang, Jun-Li Ca. Brain-derived neurotrophic factor-mediated projection-specific regulation of depressive-like and nociceptive behaviors in the mesolimbic reward circuitry. Pain. vol 159. issue 1. 2019-03-21. PMID:29076919. |
we demonstrated that cms decreased the firing activity in vta projecting to medial prefrontal cortex (vta → mpfc), but not in vta to nucleus accumbens (vta → nac), da neurons. |
2019-03-21 |
2023-08-13 |
mouse |
| Aman Asif-Malik, Daniel Dautan, Andrew M J Young, Todor V Gerdjiko. Altered cortico-striatal crosstalk underlies object recognition memory deficits in the sub-chronic phencyclidine model of schizophrenia. Brain structure & function. vol 222. issue 7. 2019-02-21. PMID:28293729. |
given that network activity across regions encompassing medial prefrontal cortex (mpfc) and nucleus accumbens (nac) plays a significant role in motivational and cognitive tasks, we measured activity across cortico-striatal pathways in pcp-treated rats to characterize neural enabling and encoding of task performance in a novel object recognition task. |
2019-02-21 |
2023-08-13 |
rat |
| Ying Zeng, Di Hu, Wei Yang, Emi Hayashinaka, Yasuhiro Wada, Yasuyoshi Watanabe, Qunli Zeng, Yilong Cu. A voxel-based analysis of neurobiological mechanisms in placebo analgesia in rats. NeuroImage. vol 178. 2019-02-19. PMID:29883731. |
we show here that gabapentin-based pavlovian conditioning successfully induced placebo analgesia in neuropathic pain model rats and hierarchical brain regions are involved in placebo analgesia in rats, including the prelimbic cortex (prl) of the medial prefrontal cortex (mpfc), nucleus accumbens (nac), ventrolateral periaqueductal gray matter (vlpag), etc. |
2019-02-19 |
2023-08-13 |
rat |
| Daniel F Hill, Kate L Parent, Christopher W Atcherley, Stephen L Cowen, Michael L Heie. Differential release of dopamine in the nucleus accumbens evoked by low-versus high-frequency medial prefrontal cortex stimulation. Brain stimulation. vol 11. issue 2. 2019-01-28. PMID:29239776. |
the medial prefrontal cortex (mpfc) coordinates goal-directed behaviors, which may be mediated through mpfc regulation of dopamine release in the nucleus accumbens (nac). |
2019-01-28 |
2023-08-13 |
Not clear |
| Katherine N Wright, Amanda M Dossat, Caroline E Strong, Lindsay L Sailer, Samantha M Pavlock, Mohamed Kabba. Optogenetic inhibition of medial prefrontal cortex projections to the nucleus accumbens core and methyl supplementation via L-Methionine attenuates cocaine-primed reinstatement. Integrative zoology. vol 13. issue 6. 2019-01-18. PMID:30318755. |
indeed, the medial prefrontal cortex (mpfc) projections to the nucleus accumbens (nac) are critically important for reinstated cocaine-seeking in a rodent model of cocaine relapse. |
2019-01-18 |
2023-08-13 |
rat |
| H Schoch, M Y Huerta, C M Ruiz, M R Farrell, K M Jung, J J Huang, R R Campbell, D Piomelli, S V Mahle. Adolescent cannabinoid exposure effects on natural reward seeking and learning in rats. Psychopharmacology. vol 235. issue 1. 2018-12-11. PMID:29022083. |
as a result, adolescent cannabinoid receptor stimulation (acrs) with phytocannabinoids or synthetic agonists like "spice" cause robust and persistent changes in both behavior and circuit architecture in rodents, including in reward-related regions like medial prefrontal cortex and nucleus accumbens (nac). |
2018-12-11 |
2023-08-13 |
rat |
| Raúl López-Arnau, Mario Buenrostro-Jáuregui, Jorge Camarasa, David Pubill, Elena Escubed. Effect of the combination of mephedrone plus ethanol on serotonin and dopamine release in the nucleus accumbens and medial prefrontal cortex of awake rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 391. issue 3. 2018-11-26. PMID:29349706. |
in the present study, we investigated the combined effects of meph plus ethanol (etoh) on neurotransmitter release in the nucleus accumbens (nac) and the medial prefrontal cortex (mpfc). |
2018-11-26 |
2023-08-13 |
rat |
| K M Braunscheidel, J T Gass, P J Mulholland, S B Floresco, J J Woodwar. Persistent cognitive and morphological alterations induced by repeated exposure of adolescent rats to the abused inhalant toluene. Neurobiology of learning and memory. vol 144. 2018-05-08. PMID:28720405. |
to determine whether cta alters the structural plasticity of brain areas involved in set-shifting and appetitive behaviors, we quantified basal dendritic spine morphology in dii-labeled pyramidal neurons in layer 5 of the medial prefrontal cortex (mpfc) and medium spiny neurons in the nucleus accumbens (nac). |
2018-05-08 |
2023-08-13 |
human |
| Sabyasachi Dash, Muthukumar Balasubramaniam, Tanu Rana, Arthur Godino, Emily G Peck, Jeffery Shawn Goodwin, Fernando Villalta, Erin S Calipari, Eric J Nestler, Chandravanu Dash, Jui Pandhar. Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b. eNeuro. vol 4. issue 4. 2018-05-03. PMID:28828398. |
acute and chronic cocaine exposure resulted in the downregulation of mir-125b concurrent with upregulation of parp-1 in dopaminergic neuronal cells and nucleus accumbens (nac) of mice but not in the medial prefrontal cortex (pfc) or ventral tegmental area (vta). |
2018-05-03 |
2023-08-13 |
mouse |
| Alaa M Hammad, Yusuf S Althobaiti, Sujan C Das, Youssef Sar. Effects of repeated cocaine exposure and withdrawal on voluntary ethanol drinking, and the expression of glial glutamate transporters in mesocorticolimbic system of P rats. Molecular and cellular neurosciences. vol 82. 2018-04-24. PMID:28442364. |
co-exposure of cocaine and ethanol decreased the relative mrna expression and the expression of glt-1 in the nac but not in the medial prefrontal cortex (mpfc). |
2018-04-24 |
2023-08-13 |
rat |
| Devesh Mishra, Jose Ignacio Pena-Bravo, Kah-Chung Leong, Antonieta Lavin, Carmela M Reiche. Methamphetamine self-administration modulates glutamate neurophysiology. Brain structure & function. vol 222. issue 5. 2018-04-17. PMID:27709300. |
we assessed pre- and postsynaptic changes in glutamate transmission in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) following daily 6-h meth self-administration. |
2018-04-17 |
2023-08-13 |
Not clear |
| J J Walsh, M H Ha. The heterogeneity of ventral tegmental area neurons: Projection functions in a mood-related context. Neuroscience. vol 282. 2018-01-26. PMID:24931766. |
these neurons project to different brain regions, including the nucleus accumbens (nac), the medial prefrontal cortex (mpfc), and the amygdala. |
2018-01-26 |
2023-08-13 |
Not clear |