| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aiqin Zhu, Xing Zhong, Yi Zhu, Peng Li, Junxia Zhang, Yonglan Hou, Lele Son. Ratanasampil is more effective than Flunarizine in relieving migraine. The International journal of neuroscience. 2022-05-18. PMID:35583486. |
serum levels of 5-hydroxytryptamine(5-ht), brain-derived neurotrophic factor(bdnf), calcitonin gene related peptide(cgrp), nerve growth factor(ngf) and β-endorphin(β-ep) before and after therapy were measured. |
2022-05-18 |
2023-08-13 |
Not clear |
| Anna Kendall, Stina Ekman, Eva Skiöldebran. NERVE GROWTH FACTOR RECEPTORS IN EQUINE SYNOVIAL MEMBRANES VARY WITH OSTEOARTHRITIC DISEASE SEVERITY. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2022-05-17. PMID:35578994. |
nerve growth factor (ngf) is a neurotrophin that has been implicated in pain signaling, apoptosis, inflammation and proliferation. |
2022-05-17 |
2023-08-13 |
Not clear |
| Huan Yu, Tianwen Huang, William Weijia Lu, Liping Tong, Di Che. Osteoarthritis Pain. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35563035. |
we evaluate pathways associated with oa pain, such as nerve growth factor (ngf)/tropomyosin receptor kinase a (trka), calcitonin gene-related peptide (cgrp), c-c motif chemokine ligands 2 (ccl2)/chemokine receptor 2 (ccr2) and tumor necrosis factor alpha (tnf-α), interleukin-1beta (il-1β), the nod-like receptor (nlr) family, pyrin domain-containing protein 3 (nlrp3) inflammasome, and the wnt/β-catenin signaling pathway. |
2022-05-14 |
2023-08-13 |
Not clear |
| Yulin Wang, Ya Li, Zhongbing Huang, Bing Yang, Ning Mu, Zhaopu Yang, Min Deng, Xiaoming Liao, Guangfu Yin, Yu Nie, Tunan Chen, Hua M. Gene delivery of chitosan-graft-polyethyleneimine vectors loaded on scaffolds for nerve regeneration. Carbohydrate polymers. vol 290. 2022-05-13. PMID:35550777. |
arginine-glycine-aspartate (rgd)-functionalized chitosan-graft-polyethyleneimine (rcp) gene vectors were prepared through the maleic anhydride & the carbodiimide methods, and electrostatically bound with c-jun plasmids (pjun), finally loaded on poly-l-lactic acid/silk fibroin parallel fiber films to fabricate nerve scaffold (rcp/pjun-pspf@pga), which could locally deliver c-jun plasmids into scs via the mediation of rgd peptides, and upregulate the expression of nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf) in scs. |
2022-05-13 |
2023-08-13 |
Not clear |
| Helga Eyjolfsdottir, Thomas Koenig, Azadeh Karami, Per Almqvist, Göran Lind, Bengt Linderoth, Lars Wahlberg, Åke Seiger, Taher Darreh-Shori, Maria Eriksdotter, Vesna Jeli. Fast Alpha Activity in EEG of Patients With Alzheimer's Disease Is Paralleled by Changes in Cognition and Cholinergic Markers During Encapsulated Cell Biodelivery of Nerve Growth Factor. Frontiers in aging neuroscience. vol 14. 2022-05-13. PMID:35557841. |
basal forebrain cholinergic neurons are dependent on nerve growth factor (ngf) for growth and survival and these cells are among the first to degenerate in alzheimer's disease (ad). |
2022-05-13 |
2023-08-13 |
human |
| Wenxuan Zhang, Ziqiang Lin, Ailing Sun, Yongyong Shi, Qingxiong Hong, Gaofeng Zha. Curcumin ameliorates the experimental diabetic peripheral neuropathy through promotion of NGF expression in rats. Chemistry & biodiversity. 2022-05-10. PMID:35538560. |
increasing evidence suggested that inhibiting the apoptosis of schwann cells (scs) and promoting nerve growth factor (ngf) expression in sciatic nerves play key roles in preventing the onset of diabetic peripheral neuropathy (dpn). |
2022-05-10 |
2023-08-13 |
rat |
| Ahmet Bulent Yazici, Derya Guzel, Elif Merve Kurt, Betul Turkmen, Esra Yazic. Klotho, BDNF, NGF, GDNF Levels and Related Factors in Withdrawal Period in Chronic Cannabinoid Users. Indian journal of clinical biochemistry : IJCB. vol 37. issue 2. 2022-04-25. PMID:35463111. |
in this study, brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), glial derived neurotrophic factor (gdnf) and klotho serum levels of a patient group consisting of 27 chronic cannabis users according to the dsm-v and 27 healthy volunteers were compared, and their relationships with other the clinical features of other patients were evaluated. |
2022-04-25 |
2023-08-13 |
human |
| Przemyslaw Solek, Jennifer Mytych, Ewelina Sujkowska, Magdalena Grzegorczyk, Patrycja Jasiewicz, Magdalena Sowa-Kucma, Katarzyna Stachowicz, Marek Koziorowski, Anna Tabecka-Lonczynsk. Trade-offs between male fertility reduction and selected growth factors or the klotho response in a lipopolysaccharide-dependent mouse model. Toxicological research. vol 38. issue 2. 2022-04-13. PMID:35415080. |
hence, the study aimed to investigate the effect of the antidepressant drug - imipramine (tricyclic ad), and other substances with antidepressant potential (als), administered in combination or in combination with lps (an animal model of depression) on gene expression and protein synthesis of igf-2 (insulin-like growth factor 2), tgf-β1 (transforming growth factor β1), ngf (nerve growth factor), kgf (keratinocyte growth factor) and protein synthesis of vegf-a (vascular endothelial growth factor a), igf-ir (insulin-like growth factor receptor 1), egfr (epidermal growth factor receptor) and klotho in the testis of mice. |
2022-04-13 |
2023-08-13 |
mouse |
| Xingchen Dong, Huanhuan Li, Min Pei, Jie Tan, Ganjun Chen, Santai Li, Zuobin Xie, Qi Wang, Guifeng Wang, Yili Chen, Chunhe Wan. Analgesic effects of nerve growth factor-directed monoclonal antibody on diabetic neuralgia in an animal model. FEBS open bio. 2022-04-13. PMID:35417079. |
tanezumab, a monoclonal antibody which blocks nerve growth factor (ngf) signaling, has been shown to be effective in relieving the clinical symptoms of osteoarthritis pain, chronic low back pain, cancer pain induced by bone metastasis, and diabetic neuralgia. |
2022-04-13 |
2023-08-13 |
mouse |
| Simona Capsoni, Antonino Cattane. Getting Into the Brain: The Intranasal Approach to Enhance the Delivery of Nerve Growth Factor and Its Painless Derivative in Alzheimer's Disease and Down Syndrome. Frontiers in neuroscience. vol 16. 2022-04-01. PMID:35360160. |
we will also describe the main experimental facts related to the effective intranasal delivery of a mutant form of ngf [painless ngf, human nerve growth factor painless (hngfp)] in mouse models of alzheimer's disease and compare it to other ways to deliver ngf to the brain. |
2022-04-01 |
2023-08-13 |
mouse |
| Masayuki Miyagi, Kentaro Uchida, Sho Inoue, Shotaro Takano, Mitsufumi Nakawaki, Ayumu Kawakubo, Hiroyuki Sekiguchi, Toshiyuki Nakazawa, Takayuki Imura, Wataru Saito, Eiki Shirasawa, Akiyoshi Kuroda, Shinsuke Ikeda, Yuji Yokozeki, Yusuke Mimura, Tsutomu Akazawa, Masashi Takaso, Gen Inou. A High Body Mass Index and the Vacuum Phenomenon Upregulate Pain-Related Molecules in Human Degenerated Intervertebral Discs. International journal of molecular sciences. vol 23. issue 6. 2022-03-25. PMID:35328395. |
pain-related molecules including tumor necrosis factor alpha (tnf-alpha), interleukin (il)-6, calcitonin gene-related peptide (cgrp), microsomal prostaglandin e synthase-1 (mpges1), and nerve growth factor (ngf) were determined. |
2022-03-25 |
2023-08-13 |
human |
| Yuta Murai, Akihiro Sekiguchi, Taeko Hirakawa, Seigo Usuki, Yasuyuki Igarashi, Kenji Mond. Evaluation of chiral N,N-dimethyl-sphingosine for the interaction between nerve growth factor and tropomyosin receptor kinase A. Chirality. 2022-03-17. PMID:35297105. |
nerve growth factor (ngf) is one of the peripheral nervous system targeted pain factors that interact with tropomyosin receptor kinase a (trka). |
2022-03-17 |
2023-08-13 |
mouse |
| Hyeon-Jeong Yoon, Won-Hee Jang, Susun An, Yong Sok Ji, Kyung Chul Yoo. Tear Neuromediators in Subjects with and without Dry Eye According to Ocular Sensitivity. Chonnam medical journal. vol 58. issue 1. 2022-02-16. PMID:35169558. |
the concentrations of the tear neuromediators, including nerve growth factor (ngf), serotonin, calcitonin gene-related peptide (cgrp), substance p, neuropeptide y, and vasoactive intestinal peptide were measured using the enzyme-linked immune sorbent assay. |
2022-02-16 |
2023-08-13 |
human |
| Sugang Shen, Qiqi Wang, Xueni Wang, Jiachun Ding, Fan Chen, Ying Xiao, Tao Qin, Weikun Qian, Jiahui Li, Qingyong Ma, Jiguang M. Nodal Enhances Perineural Invasion in Pancreatic Cancer by Promoting Tumor-Nerve Convergence. Journal of healthcare engineering. vol 2022. 2022-02-07. PMID:35126957. |
the results illustrate that nodal upregulates ngf (nerve growth factor), bdnf (brain-derived neurotrophic factor), and gdnf (glial cell line-derived neurotrophic factor) expression in pancreatic cancer cells and promotes cancer cell migration/invasion. |
2022-02-07 |
2023-08-13 |
human |
| Muaz Belviranlı, Nilsel Okuda. Differential effects of voluntary and forced exercise trainings on spatial learning ability and hippocampal biomarkers in aged female rats. Neuroscience letters. 2022-02-05. PMID:35121056. |
after the behavioral test, hippocampus tissues were taken for the analysis of synaptophysin, acetylcholinesterase (ache), brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), malondialdehyde (mda), protein carbonyl (pc), glutathione (gsh) and superoxide dismutase (sod). |
2022-02-05 |
2023-08-13 |
rat |
| Ka Yi Cha. Structural study of regulated intramembrane proteolysis of p75NTR by γ-secretase. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35109074. |
when binding to nerve growth factor (ngf), p75ntr maintains cell survival and proliferation; on the contrary, p75ntr induces apoptosis when the ngf precursor (pro-ngf) binds onto p75ntr. |
2022-02-03 |
2023-08-13 |
Not clear |
| Huirong Guo, Yuming Ren, Bailing Huang, Junru Wang, Xuhuang Yang, Yali Wan. Psychological Status, Compliance, Serum Brain-Derived Neurotrophic Factor, and Nerve Growth Factor Levels of Patients with Depression after Augmented Mindfulness-Based Cognitive Therapy. Genetics research. vol 2022. 2022-01-24. PMID:35069013. |
the present study aimed to analyze the effects of augmented mbct along with standard treatment dominated by pharmacotherapy on psychological state, compliance, brain-derived neurotrophic factor (bdnf), and nerve growth factor (ngf) expression levels in patients with depression. |
2022-01-24 |
2023-08-13 |
Not clear |
| Sonia Do Carmo, Benjamin Kannel, A Claudio Cuell. The Nerve Growth Factor Metabolic Pathway Dysregulation as Cause of Alzheimer's Cholinergic Atrophy. Cells. vol 11. issue 1. 2022-01-11. PMID:35011577. |
the cholinergic phenotype of this neuronal system, involved in numerous cognitive mechanisms, is tightly dependent on the target-derived nerve growth factor (ngf). |
2022-01-11 |
2023-08-13 |
Not clear |
| Xiang Gao, Weinan Cheng, Xiaoyi Zhang, Zhengyu Zhou, Zhaozhao Ding, Xiaozhong Zhou, Qiang Lu, David L Kapla. Nerve Growth Factor-Laden Anisotropic Silk Nanofiber Hydrogels to Regulate Neuronal/Astroglial Differentiation for Scarless Spinal Cord Repair. ACS applied materials & interfaces. 2022-01-10. PMID:35006667. |
in this study, the nerve growth factor (ngf) was immobilized in silk protein nanofiber hydrogels with hierarchical anisotropic microstructures to fabricate bioactive systems that provide multiple physical and biological cues to address spinal cord injury (sci). |
2022-01-10 |
2023-08-13 |
Not clear |
| Yihan Wang, Yang Liu, Jieting Liu, Min Wang, Yingbin Wan. Coadministration of Curcumin and Hydromorphone Hydrochloride Alleviates Postoperative Pain in Rats. Biological & pharmaceutical bulletin. vol 45. issue 1. 2022-01-04. PMID:34980778. |
mechanistically, curcumin + hh suppressed protein expression of stromal cell-derived factor-1 (sdf-1), cxc chemokine receptor 4 (cxcr4), p-akt, and c-fos while enhancing protein expression of nerve growth factor (ngf) in the dorsal root ganglia (drg) of model rats. |
2022-01-04 |
2023-08-13 |
rat |