| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sonia Do Carmo, Benjamin Kannel, A Claudio Cuell. Nerve Growth Factor Compromise in Down Syndrome. Frontiers in aging neuroscience. vol 13. 2021-08-27. PMID:34434101. |
the basal forebrain cholinergic system relies on trophic support by nerve growth factor (ngf) to maintain its phenotype and function. |
2021-08-27 |
2023-08-13 |
Not clear |
| Michael J Castle, Fernando C Baltanás, Imre Kovacs, Alan H Nagahara, David Barba, Mark H Tuszynsk. Postmortem Analysis in a Clinical Trial of AAV2-NGF Gene Therapy for Alzheimer's Disease Identifies a Need for Improved Vector Delivery. Human gene therapy. vol 31. issue 7-8. 2021-08-18. PMID:32126838. |
nerve growth factor (ngf) gene therapy rescues and stimulates cholinergic neurons, which degenerate in alzheimer's disease (ad). |
2021-08-18 |
2023-08-13 |
Not clear |
| Katharina Sessler, Vivian Blechschmidt, Ulrich Hoheisel, Siegfried Mense, Lucas Schirmer, Rolf-Detlef Treed. Spinal cord fractalkine (CX3CL1) signaling is critical for neuronal sensitization in experimental nonspecific, myofascial low back pain. Journal of neurophysiology. vol 125. issue 5. 2021-08-17. PMID:33596743. |
we studied the involvement of fractalkine signaling in latent and manifest spinal sensitization induced by two injections of nerve growth factor (ngf) into the lumbar multifidus muscle as a model for myofascial low back pain. |
2021-08-17 |
2023-08-13 |
Not clear |
| Akram Alizadeh, Lida Moradi, Majid Katebi, Jafar Ai, Mahmoud Azami, Borhan Moradveisi, Seyed Nasser Osta. Delivery of injectable thermo-sensitive hydrogel releasing nerve growth factor for spinal cord regeneration in rat animal model. Journal of tissue viability. vol 29. issue 4. 2021-08-16. PMID:32839065. |
the main goal of this study was to explore the beneficial effect of nerve growth factor (ngf)-overexpressing of human adipose-derived mesenchymal stem cells (hadscs) encapsulated in injectable chitosan/β-glycerophosphate/hydroxyethylcellulose (cs/β-gp/hec) hydrogel for spinal cord regeneration. |
2021-08-16 |
2023-08-13 |
human |
| Femke Mathot, Nadia Rbia, Roman Thaler, Allan B Dietz, Andre J van Wijnen, Allen T Bishop, Alexander Y Shi. Gene expression profiles of human adipose-derived mesenchymal stem cells dynamically seeded on clinically available processed nerve allografts and collagen nerve guides. Neural regeneration research. vol 16. issue 8. 2021-08-13. PMID:33433492. |
neurotrophic [nerve growth factor (ngf), glial cell line-derived neurotrophic factor (gdnf), pleiotrophin (ptn), growth associated protein 43 (gap43) and brain-derived neurotrophic factor (bdnf)], myelination [peripheral myelin protein 22 (pmp22) and myelin protein zero (mpz)], angiogenic [platelet endothelial cell adhesion molecule 1 (pecam1/cd31) and vascular endothelial cell growth factor alpha (vegfa)], extracellular matrix (ecm) [collagen type alpha i (col1a1), collagen type alpha iii (col3a1), fibulin 1 (fbln1) and laminin subunit beta 2 (lamb2)] and cell surface marker cluster of differentiation 96 (cd96) gene expression was quantified. |
2021-08-13 |
2023-08-13 |
human |
| Agustin Benitez, Raul Riquelme, Miguel Del Campo, Camila Araya, Hernan E Lar. Nerve Growth Factor: A Dual Activator of Noradrenergic and Cholinergic Systems of the Rat Ovary. Frontiers in endocrinology. vol 12. 2021-08-10. PMID:33716987. |
the nerve growth factor (ngf) was the first neurotrophic factor found to regulate ovarian noradrenergic neurons and the cholinergic neurons in the central nervous system. |
2021-08-10 |
2023-08-13 |
rat |
| Daniela Silva Santos, Liciane Fernandes Medeiros, Dirson João Stein, Isabel Cristina De Macedo, Diego Evandro Da Silva Rios, Carla De Oliveira, Roberta Ströher Toledo, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. Bimodal transcranial direct current stimulation reduces alcohol consumption and induces long-term neurochemical changes in rats with neuropathic pain. Neuroscience letters. vol 759. 2021-08-06. PMID:34111512. |
brain structures were collected to evaluate the number of neuropeptide y (npy)-positive neurons, neurites, and argyrophilic grains by immunohistochemistry, and brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), interleukin (il)-6, and il-10 by elisa. |
2021-08-06 |
2023-08-13 |
rat |
| Gehan Ahmed Mostafa, Nagwa Abdel Meguid, Abeer Al Sayed Shehab, Amal Elsaeid, Mahmoud Mahe. Plasma levels of nerve growth factor in Egyptian autistic children: Relation to hyperserotonemia and autoimmunity. Journal of neuroimmunology. vol 358. 2021-08-02. PMID:34214954. |
nerve growth factor (ngf) stimulates the proliferation of b lymphocytes with production of antibodies and also increases mast cell serotonin release. |
2021-08-02 |
2023-08-13 |
Not clear |
| Rodrigo A Carrasco, Carlos E Leonardi, Sergio Pezo, Gregg P Adam. Hypothalamic involvement and the role of progesterone in the NGF-induced LH surge pathway. Reproduction (Cambridge, England). vol 162. issue 2. 2021-07-30. PMID:34128825. |
to elucidate the mechanism by which nerve growth factor (ngf) influences the lh secretory pathway in camelids, a series of experiments were done to determine the involvement of the hypothalamus (experiment 1), the role of gnrh neurons (experiment 2), and the effect of progesterone (experiment 3) on the ngf-induced lh surge and ovulation in llamas. |
2021-07-30 |
2023-08-13 |
Not clear |
| Maria Eriksdotter, Sumonto Mitr. Gene and cell therapy for the nucleus basalis of Meynert with NGF in Alzheimer's disease. Handbook of clinical neurology. vol 179. 2021-07-28. PMID:34225964. |
in recent years, other approaches to influence the degenerating cholinergic system in ad focusing on nerve growth factor (ngf) have been undertaken. |
2021-07-28 |
2023-08-13 |
Not clear |
| Deirdre A Killebrew, Kimberly S Williams, Youmei Xie, Frank Longo, Rick B Meeke. Suppression of HIV-associated Macrophage Activation by a p75 Neurotrophin Receptor Ligand. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2021-07-23. PMID:34296391. |
previous studies indicated that nerve growth factor (ngf) and prongf differentially regulate the phenotype of macrophages and microglia via actions at tropomyosin receptor kinase a (trka) and p75 neurotrophin receptors (p75 |
2021-07-23 |
2023-08-13 |
Not clear |
| Sze Yuen Lew, Siew Huah Lim, Lee Wei Lim, Kah Hui Won. Neuroprotective effects of Hericium erinaceus (Bull.: Fr.) Pers. against high-dose corticosterone-induced oxidative stress in PC-12 cells. BMC complementary medicine and therapies. vol 20. issue 1. 2021-07-21. PMID:33176761. |
it has numerous pharmacological effects including immunomodulatory, anti-tumour, anti-microbial, anti-aging and stimulation of nerve growth factor (ngf) synthesis, but little is known about its potential role in negating the detrimental effects of oxidative stress in depression. |
2021-07-21 |
2023-08-13 |
rat |
| Cameron R Moattari, Richard D Granstei. Neuropeptides and neurohormones in immune, inflammatory and cellular responses to ultraviolet radiation. Acta physiologica (Oxford, England). vol 232. issue 1. 2021-07-07. PMID:33724698. |
in this review, we will focus on both animal and human studies that elucidate the roles of calcitonin gene-related peptide (cgrp), substance p (sp), nerve growth factor (ngf), nitric oxide and proopiomelanocortin (pomc) derivatives in mediating immune and inflammatory effects of exposure to uvr as well as other cell biologic effects of uvr exposure. |
2021-07-07 |
2023-08-13 |
human |
| Meiya Gao, Xinyu Yan, Yanzhu Lu, Linghuan Ren, Shizhen Zhang, Xiaoqi Zhang, Qianyun Kuang, Lu Liu, Jing Zhou, Yan Wang, Wenli Lai, Hu Lon. Retrograde nerve growth factor signaling modulates tooth mechanical hyperalgesia induced by orthodontic tooth movement via acid-sensing ion channel 3. International journal of oral science. vol 13. issue 1. 2021-07-02. PMID:34088898. |
nerve growth factor (ngf) is upregulated in periodontium and may modulate tooth mechanical hyperalgesia. |
2021-07-02 |
2023-08-13 |
rat |
| L-N Pei, X-H Liu, H Zhang, J Zhu, Z Gao, M-Z B. Clinical efficacy of mouse nerve growth factor plus nimodipine in neonatal intracranial hemorrhage and its effect on plasma PAF, CNP, MMP-2, and neurological function. European review for medical and pharmacological sciences. vol 25. issue 1. 2021-06-30. PMID:33506910. |
to investigate the clinical efficacy of combination of mouse nerve growth factor (ngf) and nimodipine in the treatment of neonatal intracranial hemorrhage (nich) and its effect on plasma platelet-activating factor (paf), c-type natriuretic peptide (cnp), matrix metalloproteinase-2 (mmp-2), and neurological function. |
2021-06-30 |
2023-08-13 |
mouse |
| Wei Zheng Eu, Yu-Ju Chen, Wei-Ting Chen, Kuan-Yu Wu, Cheng-Yu Tsai, Sin-Jhong Cheng, Roderick N Carter, Guo-Jen Huan. The effect of nerve growth factor on supporting spatial memory depends upon hippocampal cholinergic innervation. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33723225. |
nerve growth factor (ngf) gene therapy has been used in clinical trials of alzheimer's disease. |
2021-06-28 |
2023-08-13 |
mouse |
| Juanjuan Lyu, Man Wang, Xinjiang Kang, Huadong Xu, Zhongming Cao, Tao Yu, Keli Huang, Jin Wu, Xinchuan Wei, Qian Le. Macrophage-mediated regulation of catecholamines in sympathetic neural remodeling after myocardial infarction. Basic research in cardiology. vol 115. issue 5. 2021-06-25. PMID:32767120. |
both in vivo and ex vivo electrophysiology examinations showed that the vulnerability to vas induced by mi was alleviated by macrophage depletion with clodronate and β1-adrenergic blockade with metoprolol, which was in line with circulating and peri-infarct norepinephrine levels, sympathetic reinnervation, and the expression of nerve growth factor (ngf) 7 days after surgery. |
2021-06-25 |
2023-08-13 |
mouse |
| Alejandra Machado, Daniel Ferreira, Michel J Grothe, Helga Eyjolfsdottir, Per M Almqvist, Lena Cavallin, Göran Lind, Bengt Linderoth, Åke Seiger, Stefan Teipel, Lars U Wahlberg, Lars-Olof Wahlund, Eric Westman, Maria Eriksdotte. The cholinergic system in subtypes of Alzheimer's disease: an in vivo longitudinal MRI study. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:32375872. |
we investigated volume of the basal forebrain, hippocampus, and precuneus in atrophy subtypes of ad and explored the relevance of subtype stratification in a small clinical trial on encapsulated cell biodelivery (ecb) of nerve growth factor (ngf) to the basal forebrain. |
2021-06-24 |
2023-08-13 |
Not clear |
| David A Seminowicz, Katarzyna Bilska, Nahian S Chowdhury, Patrick Skippen, Samantha K Millard, Alan K I Chiang, Shuo Chen, Andrew J Furman, Siobhan M Schabru. A novel cortical biomarker signature for predicting pain sensitivity: protocol for the PREDICT longitudinal analytical validation study. Pain reports. vol 5. issue 4. 2021-06-22. PMID:32766469. |
the predict study aims to undertake analytical validation of a novel peak alpha frequency (paf) and corticomotor excitability (cme) biomarker signature using a human model of the transition to sustained myofascial temporomandibular pain (masseter intramuscular injection of nerve growth factor [ngf]). |
2021-06-22 |
2023-08-13 |
human |
| Ewa Fudalej, Magdalena Justyniarska, Kaja Kasarełło, Jacek Dziedziak, Jacek P Szaflik, Agnieszka Cudnoch-Jędrzejewsk. Neuroprotective Factors of the Retina and Their Role in Promoting Survival of Retinal Ganglion Cells: A Review. Ophthalmic research. vol 64. issue 3. 2021-06-22. PMID:33454713. |
in this review, we summarize the role of some neuroprotective factors in rgc injury: ciliary neurotrophic factor (cntf), nerve growth factor (ngf), brain-derived neurotrophic factor, vascular endothelial growth factor, pigment epithelium-derived factor, glial cell line-derived neurotrophic factor, and norrin. |
2021-06-22 |
2023-08-13 |
Not clear |