| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Naohiro Yamaguchi, Nobuyuki Takahashi, Le Xu, Oliver Smithies, Gerhard Meissne. Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca release channel. The Journal of clinical investigation. vol 117. issue 5. 2007-06-13. PMID:17431507. |
taken together, the data indicate that impaired cam inhibition of ryr2, associated with defective sarcoplasmic reticulum ca(2+) release and altered gene expression, leads to cardiac hypertrophy and early death. |
2007-06-13 |
2023-08-12 |
mouse |
| Xiao-dong Wu, De-zai Dai, Qiu-pin Zhang, Feng Ga. Propranolol and verapamil inhibit mRNA expression of RyR2 and SERCA in L-thyroxin-induced rat ventricular hypertrophy. Acta pharmacologica Sinica. vol 25. issue 3. 2004-08-06. PMID:15000889. |
propranolol and verapamil inhibit mrna expression of ryr2 and serca in l-thyroxin-induced rat ventricular hypertrophy. |
2004-08-06 |
2023-08-12 |
rat |
| Xiao-dong Wu, De-zai Dai, Qiu-pin Zhang, Feng Ga. Propranolol and verapamil inhibit mRNA expression of RyR2 and SERCA in L-thyroxin-induced rat ventricular hypertrophy. Acta pharmacologica Sinica. vol 25. issue 3. 2004-08-06. PMID:15000889. |
to study the alteration in the mrna level of cardiac ryanodine receptor 2 (ryr2) and sarco-endoplasmic reticulum ca2+-atpase (serca) in l-thyroxin-induced hypertrophy. |
2004-08-06 |
2023-08-12 |
rat |
| Steven Reiken, Marta Gaburjakova, Silvia Guatimosim, Ana M Gomez, Jeanine D'Armiento, Daniel Burkhoff, Jie Wang, Guy Vassort, W Jonathan Lederer, Andrew R Mark. Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol. The Journal of biological chemistry. vol 278. issue 1. 2003-02-10. PMID:12401811. |
because heart failure is a progressive disease that often evolves from hypertrophy, we analyzed the ryr2 macromolecular complex in several animal models of cardiomyopathy that lead to heart failure, including hypertrophy, and at different stages of disease progression. |
2003-02-10 |
2023-08-12 |
human |
| L Zhao, A Sebkhi, D J Nunez, L Long, C S Haley, J Szpirer, C Szpirer, A J Williams, M R Wilkin. Right ventricular hypertrophy secondary to pulmonary hypertension is linked to rat chromosome 17: evaluation of cardiac ryanodine Ryr2 receptor as a candidate. Circulation. vol 103. issue 3. 2001-04-26. PMID:11157698. |
right ventricular hypertrophy secondary to pulmonary hypertension is linked to rat chromosome 17: evaluation of cardiac ryanodine ryr2 receptor as a candidate. |
2001-04-26 |
2023-08-12 |
rat |