| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Young-Goo Han, Nathalie Spassky, Miriam Romaguera-Ros, Jose-Manuel Garcia-Verdugo, Andrea Aguilar, Sylvie Schneider-Maunoury, Arturo Alvarez-Buyll. Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells. Nature neuroscience. vol 11. issue 3. 2008-06-16. PMID:18297065. |
we found that radial astrocytes, the postnatal progenitors in the dentate gyrus, failed to develop after embryonic ablation of ciliary genes or smoothened (smo), an essential component for sonic hedgehog (shh) signaling. |
2008-06-16 |
2023-08-12 |
mouse |
| Shuhong Huang, Jing He, Xiaoli Zhang, Yuehong Bian, Ling Yang, Guorui Xie, Kefei Zhang, Wendell Tang, Arwen A Stelter, Qian Wang, Hongwei Zhang, Jingwu Xi. Activation of the hedgehog pathway in human hepatocellular carcinomas. Carcinogenesis. vol 27. issue 7. 2006-08-22. PMID:16501253. |
specific inhibition of hedgehog signaling in these three cell lines by smoothened (smo) antagonist, kaad-cyclopamine, or with shh neutralizing antibodies decreases expression of hedgehog target genes, inhibits cell growth and results in apoptosis. |
2006-08-22 |
2023-08-12 |
human |
| Sunayana B Banerjee, Rajeev Rajendran, Brian G Dias, Uma Ladiwala, Shubha Tole, Vidita A Vaidy. Recruitment of the Sonic hedgehog signalling cascade in electroconvulsive seizure-mediated regulation of adult rat hippocampal neurogenesis. The European journal of neuroscience. vol 22. issue 7. 2006-01-23. PMID:16197497. |
in addition, both acute and chronic ecs decreased smoothened (smo) mrna, the other component of the shh receptor complex, selectively within the dentate gyrus. |
2006-01-23 |
2023-08-12 |
rat |
| E Traiffort, D Charytoniuk, L Watroba, H Faure, N Sales, M Rua. Discrete localizations of hedgehog signalling components in the developing and adult rat nervous system. The European journal of neuroscience. vol 11. issue 9. 1999-11-24. PMID:10510184. |
we have performed a detailed localization of cells expressing transcripts of shh, ptc, smo and gli1 in brain and spinal cord of the adult rat as well as in the developing cerebellum. |
1999-11-24 |
2023-08-12 |
rat |
| E Traiffort, D A Charytoniuk, H Faure, M Rua. Regional distribution of Sonic Hedgehog, patched, and smoothened mRNA in the adult rat brain. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489757. |
within the cerebellum, shh, ptc, and smo transcripts were colocalized in the purkinje cell layer. |
1998-03-12 |
2023-08-12 |
mouse |