| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michelle Neal. Efficacy and safety of cannabis for treating children with refractory epilepsy. Nursing children and young people. vol 29. issue 7. 2018-01-09. PMID:29115760. |
cannabis may reduce seizures in some children and young people with refractory epilepsy, however, its success may be affected by aetiology of the epilepsy or concomitant anti-epileptic drug use, and a therapeutic dose has not been found. |
2018-01-09 |
2023-08-13 |
human |
| Michelle Neal. Efficacy and safety of cannabis for treating children with refractory epilepsy. Nursing children and young people. vol 29. issue 7. 2018-01-09. PMID:29115760. |
nurses who are aware of patients and families wishing to trial cannabis for refractory epilepsy should have full and frank discussions. |
2018-01-09 |
2023-08-13 |
human |
| Jacqueline S Gofshteyn, Angus Wilfong, Orrin Devinsky, Judith Bluvstein, Joshi Charuta, Michael A Ciliberto, Linda Laux, Eric D Mars. Cannabidiol as a Potential Treatment for Febrile Infection-Related Epilepsy Syndrome (FIRES) in the Acute and Chronic Phases. Journal of child neurology. vol 32. issue 1. 2018-01-05. PMID:27655472. |
cannabidiol as a potential treatment for febrile infection-related epilepsy syndrome (fires) in the acute and chronic phases. |
2018-01-05 |
2023-08-13 |
human |
| Cristiane R de Carvalho, Alexandre A Hoeller, Pedro L C Franco, Athos P S Martini, Flávia M S Soares, Katia Lin, Rui D Prediger, Benjamin J Whalley, Roger Wal. The cannabinoid CB2 receptor-specific agonist AM1241 increases pentylenetetrazole-induced seizure severity in Wistar rats. Epilepsy research. vol 127. 2018-01-02. PMID:27608434. |
the potential efficacy of cannabinoid receptor ligands for the treatment of epilepsy remains controversial; cannabis components that act via cannabinoid type 1 (cb1) receptors produce anticonvulsant effects in animal models despite treatment with the cb receptor agonist reliably inducing convulsions in various species. |
2018-01-02 |
2023-08-13 |
rat |
| Rima Nabbout, Carol S Camfield, Danielle M Andrade, Alexis Arzimanoglou, Catherine Chiron, Joyce A Cramer, Jacqueline A French, Eric Kossoff, Marco Mula, Peter R Camfiel. Treatment issues for children with epilepsy transitioning to adult care. Epilepsy & behavior : E&B. vol 69. 2017-12-20. PMID:28188045. |
some aeds used during childhood, such as stiripentol, vigabatrin, and cannabidiol, are unfamiliar to adult epilepsy specialists. |
2017-12-20 |
2023-08-13 |
Not clear |
| Moran Hausman-Kedem, Uri Krame. Efficacy of Medical Cannabis for Treatment of Refractory Epilepsy in Children and Adolescents with Emphasis on the Israeli Experience. The Israel Medical Association journal : IMAJ. vol 19. issue 2. 2017-11-30. PMID:28457054. |
efficacy of medical cannabis for treatment of refractory epilepsy in children and adolescents with emphasis on the israeli experience. |
2017-11-30 |
2023-08-13 |
Not clear |
| Ethan B Russ. Cannabidiol Claims and Misconceptions. Trends in pharmacological sciences. vol 38. issue 3. 2017-10-10. PMID:28089139. |
once a widely ignored phytocannabinoid, cannabidiol now attracts great therapeutic interest, especially in epilepsy and cancer. |
2017-10-10 |
2023-08-13 |
Not clear |
| Evan C Rosenberg, Jay Louik, Erin Conway, Orrin Devinsky, Daniel Friedma. Quality of Life in Childhood Epilepsy in pediatric patients enrolled in a prospective, open-label clinical study with cannabidiol. Epilepsia. vol 58. issue 8. 2017-08-17. PMID:28617940. |
quality of life in childhood epilepsy in pediatric patients enrolled in a prospective, open-label clinical study with cannabidiol. |
2017-08-17 |
2023-08-13 |
Not clear |
| Evan C Rosenberg, Jay Louik, Erin Conway, Orrin Devinsky, Daniel Friedma. Quality of Life in Childhood Epilepsy in pediatric patients enrolled in a prospective, open-label clinical study with cannabidiol. Epilepsia. vol 58. issue 8. 2017-08-17. PMID:28617940. |
recent clinical trials indicate that cannabidiol (cbd) may reduce seizure frequency in pediatric patients with certain forms of treatment-resistant epilepsy. |
2017-08-17 |
2023-08-13 |
Not clear |
| Lauren Treat, Kevin E Chapman, Kathryn L Colborn, Kelly G Knup. Duration of use of oral cannabis extract in a cohort of pediatric epilepsy patients. Epilepsia. vol 58. issue 1. 2017-06-21. PMID:27859038. |
duration of use of oral cannabis extract in a cohort of pediatric epilepsy patients. |
2017-06-21 |
2023-08-13 |
Not clear |
| Lauren Treat, Kevin E Chapman, Kathryn L Colborn, Kelly G Knup. Duration of use of oral cannabis extract in a cohort of pediatric epilepsy patients. Epilepsia. vol 58. issue 1. 2017-06-21. PMID:27859038. |
oral cannabis extracts (oces) are being used in the treatment of epilepsy with increasing rates in the united states following product legalization; however, no studies demonstrate clear efficacy. |
2017-06-21 |
2023-08-13 |
Not clear |
| Reesha R Patel, Cindy Barbosa, Tatiana Brustovetsky, Nickolay Brustovetsky, Theodore R Cummin. Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol. Brain : a journal of neurology. vol 139. issue Pt 8. 2017-06-05. PMID:27267376. |
exogenous as well as endogenous cannabinoids have been shown to target voltage-gated sodium channels and cannabidiol has recently received attention for its potential efficacy in the treatment of childhood epilepsies. |
2017-06-05 |
2023-08-13 |
human |
| Reesha R Patel, Cindy Barbosa, Tatiana Brustovetsky, Nickolay Brustovetsky, Theodore R Cummin. Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol. Brain : a journal of neurology. vol 139. issue Pt 8. 2017-06-05. PMID:27267376. |
these findings suggest that cannabidiol could be exerting its anticonvulsant effects, at least in part, through its actions on voltage-gated sodium channels, and resurgent current may be a promising therapeutic target for the treatment of epilepsy syndromes. |
2017-06-05 |
2023-08-13 |
human |
| Evan J Hess, Kirsten A Moody, Alexandra L Geffrey, Sarah F Pollack, Lauren A Skirvin, Patricia L Bruno, Jan L Paolini, Elizabeth A Thiel. Cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complex. Epilepsia. vol 57. issue 10. 2017-06-05. PMID:27696387. |
cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complex. |
2017-06-05 |
2023-08-13 |
Not clear |
| D S Redd. The Utility of Cannabidiol in the Treatment of Refractory Epilepsy. Clinical pharmacology and therapeutics. vol 101. issue 2. 2017-05-29. PMID:27506704. |
the utility of cannabidiol in the treatment of refractory epilepsy. |
2017-05-29 |
2023-08-13 |
Not clear |
| Víctor Manuel Rivera-Olmos, Marisela C Parra-Berna. [Cannabis: Effects in the Central Nervous System. Therapeutic, societal and legal consequences]. Revista medica del Instituto Mexicano del Seguro Social. vol 54. issue 5. 2017-05-03. PMID:27428345. |
systematic reviews show evidence of therapeutic effectiveness of therapeutic marijuana only for certain symptoms of multiple sclerosis (spasticity, spasms and pain), despite attempts for its widespread use, including refractory childhood epilepsy. |
2017-05-03 |
2023-08-13 |
Not clear |
| Antonio Leo, Emilio Russo, Maurizio Eli. Cannabidiol and epilepsy: Rationale and therapeutic potential. Pharmacological research. vol 107. 2017-03-27. PMID:26976797. |
cannabidiol and epilepsy: rationale and therapeutic potential. |
2017-03-27 |
2023-08-13 |
Not clear |
| Mahshid Hosseinzadeh, Sara Nikseresht, Fariba Khodagholi, Nima Naderi, Nader Maghsoud. Cannabidiol Post-Treatment Alleviates Rat Epileptic-Related Behaviors and Activates Hippocampal Cell Autophagy Pathway Along with Antioxidant Defense in Chronic Phase of Pilocarpine-Induced Seizure. Journal of molecular neuroscience : MN. vol 58. issue 4. 2016-12-26. PMID:26738731. |
in this study, we investigated alteration of seizure scores, autophagy pathway proteins, and antioxidant status in hippocampal cells during the chronic phase of pilocarpine-induced epilepsy after treatment with cannabidiol. |
2016-12-26 |
2023-08-13 |
rat |
| Mahshid Hosseinzadeh, Sara Nikseresht, Fariba Khodagholi, Nima Naderi, Nader Maghsoud. Cannabidiol Post-Treatment Alleviates Rat Epileptic-Related Behaviors and Activates Hippocampal Cell Autophagy Pathway Along with Antioxidant Defense in Chronic Phase of Pilocarpine-Induced Seizure. Journal of molecular neuroscience : MN. vol 58. issue 4. 2016-12-26. PMID:26738731. |
cannabidiol (100 ng, intracerebroventricular injection) delayed the chronic phase of epilepsy. |
2016-12-26 |
2023-08-13 |
rat |
| Richard S McLachla. Marijuana: a time-honored but untested treatment for epilepsy. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 42. issue 2. 2016-12-15. PMID:25715711. |
marijuana: a time-honored but untested treatment for epilepsy. |
2016-12-15 |
2023-08-13 |
Not clear |