| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chiara Ceci, Martina Proietti Onori, Simone Macrì, Giovanni Laviol. Interaction between the endocannabinoid and serotonergic system in the exhibition of head twitch response in four mouse strains. Neurotoxicity research. vol 27. issue 3. 2015-11-25. PMID:25516122. |
recent evidence indicates that tetrahydrocannabinol (thc), the principal psychoactive component of cannabis, reduced in mice the head twitch responses, a tic pharmacologically induced by the selective serotonin 5-ht2 receptor agonist 2,5-dimethoxy-4-iodoamphetamine (doi). |
2015-11-25 |
2023-08-13 |
mouse |
| Karen Grewen, Andrew P Salzwedel, Wei Ga. Functional Connectivity Disruption in Neonates with Prenatal Marijuana Exposure. Frontiers in human neuroscience. vol 9. 2015-11-20. PMID:26582983. |
we measured resting state functional connectivity during unsedated sleep in infants at 2-6 weeks (+mj: 20 with pme in combination with nicotine, alcohol, opiates, and/or selective serotonin reuptake inhibitors; -mj: 23 exposed to the same other drugs without marijuana, ctr: 20 drug-free controls). |
2015-11-20 |
2023-08-13 |
Not clear |
| Omar M E Abdel-Salam, Neveen A Salem, Marwa El-Sayed El-Shamarka, Noha Al-Said Ahmed, Jihan Seid Hussein, Zakaria A El-Khya. Cannabis-induced impairment of learning and memory: effect of different nootropic drugs. EXCLI journal. vol 12. 2015-09-29. PMID:26417227. |
cannabis caused dose-dependent increases of brain serotonin, noradrenaline and dopamine. |
2015-09-29 |
2023-08-13 |
mouse |
| Christian P Müller, Judith R Homber. The role of serotonin in drug use and addiction. Behavioural brain research. vol 277. 2015-09-08. PMID:24769172. |
here we review the role of the serotonergic (5-ht) system in the establishment of drug use-associated behaviours on the one hand and the transition and maintenance of addiction on the other hand for the drugs: cocaine, amphetamine, methamphetamine, mdma (ecstasy), morphine/heroin, cannabis, alcohol, and nicotine. |
2015-09-08 |
2023-08-13 |
human |
| André Twardowschy, Maria Angélica Castiblanco-Urbina, Andres Uribe-Mariño, Audrey Francisco Biagioni, Carlos José Salgado-Rohner, José Alexandre de Souza Crippa, Norberto Cysne Coimbr. The role of 5-HT1A receptors in the anti-aversive effects of cannabidiol on panic attack-like behaviors evoked in the presence of the wild snake Epicrates cenchria crassus (Reptilia, Boidae). Journal of psychopharmacology (Oxford, England). vol 27. issue 12. 2015-01-27. PMID:23926240. |
the aim of the present study was to investigate the 5-hydroxytryptamine (5-ht) co-participation in the panicolytic-like effects of cannabidiol on the innate fear-related behaviors evoked by a prey versus predator interaction-based paradigm. |
2015-01-27 |
2023-08-12 |
mouse |
| Sara Jane Ward, Sean D McAllister, Rumi Kawamura, Ryuchi Murase, Harshini Neelakantan, Ellen A Walke. Cannabidiol inhibits paclitaxel-induced neuropathic pain through 5-HT(1A) receptors without diminishing nervous system function or chemotherapy efficacy. British journal of pharmacology. vol 171. issue 3. 2014-10-07. PMID:24117398. |
cannabidiol inhibits paclitaxel-induced neuropathic pain through 5-ht(1a) receptors without diminishing nervous system function or chemotherapy efficacy. |
2014-10-07 |
2023-08-12 |
mouse |
| Rudolf Uhe. Gene-environment interactions in severe mental illness. Frontiers in psychiatry. vol 5. 2014-06-24. PMID:24860514. |
replicated findings include an interaction between a polymorphism in the akt1 gene and cannabis use in the development of psychosis and an interaction between the length polymorphism of the serotonin transporter gene and childhood maltreatment in the development of persistent depressive disorder. |
2014-06-24 |
2023-08-13 |
Not clear |
| Roy Otten, Rutger C M E Engel. Testing bidirectional effects between cannabis use and depressive symptoms: moderation by the serotonin transporter gene. Addiction biology. vol 18. issue 5. 2014-03-10. PMID:21967091. |
testing bidirectional effects between cannabis use and depressive symptoms: moderation by the serotonin transporter gene. |
2014-03-10 |
2023-08-12 |
Not clear |
| Roy Otten, Rutger C M E Engel. Testing bidirectional effects between cannabis use and depressive symptoms: moderation by the serotonin transporter gene. Addiction biology. vol 18. issue 5. 2014-03-10. PMID:21967091. |
specifically, we concentrated on changes in cannabis use and depressive symptoms over time in a simultaneous manner and differences herein for individuals with and without the short allele of the 5-hydroxytryptamine (serotonin) transporter gene-linked polymorphic region (5-httlpr) genotype. |
2014-03-10 |
2023-08-12 |
Not clear |
| Jade M Franklin, Matt Mathew, Gonzalo A Carrasc. Cannabinoid-induced upregulation of serotonin 2A receptors in the hypothalamic paraventricular nucleus and anxiety-like behaviors in rats. Neuroscience letters. vol 548. 2014-02-07. PMID:23721787. |
recent behavioral reports suggest that repeated exposure to cannabis and synthetic cannabinoid agonists is linked with mental disorders associated with dysfunction of serotonin 2a (5-ht2a) receptor neurotransmission such as anxiety and depression. |
2014-02-07 |
2023-08-12 |
rat |
| M Ruth Pazos, Nagat Mohammed, Hector Lafuente, Martin Santos, Eva Martínez-Pinilla, Estefania Moreno, Elsa Valdizan, Julián Romero, Angel Pazos, Rafael Franco, Cecilia J Hillard, Francisco J Alvarez, Jose Martínez-Orgad. Mechanisms of cannabidiol neuroprotection in hypoxic-ischemic newborn pigs: role of 5HT(1A) and CB2 receptors. Neuropharmacology. vol 71. 2014-01-10. PMID:23587650. |
mechanisms of cannabidiol neuroprotection in hypoxic-ischemic newborn pigs: role of 5ht(1a) and cb2 receptors. |
2014-01-10 |
2023-08-12 |
Not clear |
| Francis Rodriguez Bambico, Patrick R Hattan, Jean-Philippe Garant, Gabriella Gobb. Effect of delta-9-tetrahydrocannabinol on behavioral despair and on pre- and postsynaptic serotonergic transmission. Progress in neuro-psychopharmacology & biological psychiatry. vol 38. issue 1. 2012-12-03. PMID:22386778. |
the effect of the main pharmacologically active principle in cannabis, (-)-trans-Δ(9)-tetrahydrocannabinol (delta-9-thc), on depressive behavior and on the serotonin (5-ht) system, which is implicated in the mechanism of action of antidepressants, has not been extensively clarified. |
2012-12-03 |
2023-08-12 |
rat |
| E M Rock, D Bolognini, C L Limebeer, M G Cascio, S Anavi-Goffer, P J Fletcher, R Mechoulam, R G Pertwee, L A Parke. Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus. British journal of pharmacology. vol 165. issue 8. 2012-07-27. PMID:21827451. |
cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-ht(1a) somatodendritic autoreceptors in the dorsal raphe nucleus. |
2012-07-27 |
2023-08-12 |
Not clear |
| E M Rock, D Bolognini, C L Limebeer, M G Cascio, S Anavi-Goffer, P J Fletcher, R Mechoulam, R G Pertwee, L A Parke. Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus. British journal of pharmacology. vol 165. issue 8. 2012-07-27. PMID:21827451. |
to evaluate the hypothesis that activation of somatodendritic 5-ht(1a) autoreceptors in the dorsal raphe nucleus (drn) produces the anti-emetic/anti-nausea effects of cannabidiol (cbd), a primary non-psychoactive cannabinoid found in cannabis. |
2012-07-27 |
2023-08-12 |
Not clear |
| W Xiong, B-N Koo, R Morton, L Zhan. Psychotropic and nonpsychotropic cannabis derivatives inhibit human 5-HT(3A) receptors through a receptor desensitization-dependent mechanism. Neuroscience. vol 184. 2011-09-13. PMID:21477640. |
psychotropic and nonpsychotropic cannabis derivatives inhibit human 5-ht(3a) receptors through a receptor desensitization-dependent mechanism. |
2011-09-13 |
2023-08-12 |
human |
| Erin M Rock, Jennifer M Goodwin, Cheryl L Limebeer, Aviva Breuer, Roger G Pertwee, Raphael Mechoulam, Linda A Parke. Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews. Psychopharmacology. vol 215. issue 3. 2011-09-01. PMID:21243485. |
the interaction between two non-psychotropic cannabinoids, cannabidiol (cbd) and cannabigerol (cbg), which have been reported to act as a 5-hydroxytryptamine 1a (5-ht(1a)) agonist and antagonist, respectively, was evaluated. |
2011-09-01 |
2023-08-12 |
rat |
| Y Avraham, Nc Grigoriadis, T Poutahidis, L Vorobiev, I Magen, Y Ilan, R Mechoulam, Em Berr. Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice. British journal of pharmacology. vol 162. issue 7. 2011-07-12. PMID:21182490. |
we investigated the effects of cannabidiol, a non-psychoactive constituent of cannabis sativa with anti-inflammatory properties that activates the 5-hydroxytryptamine receptor 5-ht(1a) , on brain and liver functions in a model of hepatic encephalopathy associated with fulminant hepatic failure induced in mice by thioacetamide. |
2011-07-12 |
2023-08-12 |
mouse |
| K H S Yang, D Isaev, M Morales, G Petroianu, S Galadari, M O. The effect of Δ9-tetrahydrocannabinol on 5-HT3 receptors depends on the current density. Neuroscience. vol 171. issue 1. 2011-02-02. PMID:20800662. |
the effects of Δ(9)-tetrahydrocannabinol (thc), the psychoactive component of cannabis, on the function of 5-ht type 3 (5-ht(3)) receptors were investigated using a two-electrode voltage clamp technique in xenopus oocytes, and a whole-cell patch clamp technique in rat nodose ganglion neurons. |
2011-02-02 |
2023-08-12 |
rat |
| M De Pradier, P Gorwood, B Beaufils, J Adès, C Dubertre. Influence of the serotonin transporter gene polymorphism, cannabis and childhood sexual abuse on phenotype of bipolar disorder: a preliminary study. European psychiatry : the journal of the Association of European Psychiatrists. vol 25. issue 6. 2011-01-21. PMID:20434316. |
influence of the serotonin transporter gene polymorphism, cannabis and childhood sexual abuse on phenotype of bipolar disorder: a preliminary study. |
2011-01-21 |
2023-08-12 |
Not clear |
| I Magen, Y Avraham, Z Ackerman, L Vorobiev, R Mechoulam, E M Berr. Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation. British journal of pharmacology. vol 159. issue 4. 2010-07-09. PMID:20128798. |
we aimed to demonstrate the involvement of 5-ht(1a) receptors in the therapeutic effect of cannabidiol, a non-psychoactive constituent of cannabis sativa, in a model of hepatic encephalopathy induced by bile-duct ligation (bdl) in mice. |
2010-07-09 |
2023-08-12 |
mouse |