| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gang Du, Ping Zhuang, Yuqing Zhang, Jianyu Li, Yongjie L. Neuronal firing rate and oscillatory patterns in the basal ganglia nuclei differ from those of the ventrolateral thalamus in patients with Parkinson disease. Neuroscience letters. vol 683. 2019-03-11. PMID:29913198. |
the high proportion of βfb oscillatory neurons in the stn and gpi suggests that dopaminergic deficits result in abnormal β oscillatory synchronization in the basal ganglia in the parkinsonian state. |
2019-03-11 |
2023-08-13 |
Not clear |
| Dongping Huang, Zishan Wang, Jiabin Tong, Mo Wang, Jinghui Wang, Jing Xu, Xiaochen Bai, Heng Li, Yulu Huang, Yufei Wu, Yuanyuan Ma, Mei Yu, Fang Huan. Long-term Changes in the Nigrostriatal Pathway in the MPTP Mouse Model of Parkinson's Disease. Neuroscience. vol 369. 2019-02-21. PMID:29196026. |
behavior impairment is closely related to the damage of the dopaminergic system in the basal ganglia. |
2019-02-21 |
2023-08-13 |
mouse |
| Lijun Zhang, Ming Wang, Nicholas W Sterling, Eun-Young Lee, Paul J Eslinger, Daymond Wagner, Guangwei Du, Mechelle M Lewis, Young Truong, F DuBois Bowman, Xuemei Huan. Cortical Thinning and Cognitive Impairment in Parkinson's Disease without Dementia. IEEE/ACM transactions on computational biology and bioinformatics. vol 15. issue 2. 2019-02-21. PMID:29610105. |
parkinson's disease (pd) is a progressive neurodegenerative disorder characterized clinically by motor dysfunction (bradykinesia, rigidity, tremor, and postural instability), and pathologically by the loss of dopaminergic neurons in the substantia nigra of the basal ganglia. |
2019-02-21 |
2023-08-13 |
human |
| Emily L Gill, Jeremy P Koelmel, Richard A Yost, Michael S Okun, Vinata Vedam-Mai, Timothy J Garret. Mass Spectrometric Methodologies for Investigating the Metabolic Signatures of Parkinson's Disease: Current Progress and Future Perspectives. Analytical chemistry. vol 90. issue 5. 2019-02-11. PMID:29384654. |
parkinson's disease (pd) is a neurodegenerative disorder resulting from the loss of dopaminergic neurons of the substantia nigra as well as degeneration of motor and nonmotor basal ganglia circuitries. |
2019-02-11 |
2023-08-13 |
Not clear |
| Caitlin A Sisk, Emily L Twedell, Wilma Koutstaal, Scott E Cooper, Yuhong V Jian. Implicitly-learned spatial attention is unimpaired in patients with Parkinson's disease. Neuropsychologia. vol 119. 2019-02-11. PMID:30063912. |
this result suggests that not all habit-like behaviors depend on the basal ganglia and the dopaminergic system. |
2019-02-11 |
2023-08-13 |
human |
| Robert Lindroos, Matthijs C Dorst, Kai Du, Marko Filipović, Daniel Keller, Maya Ketzef, Alexander K Kozlov, Arvind Kumar, Mikael Lindahl, Anu G Nair, Juan Pérez-Fernández, Sten Grillner, Gilad Silberberg, Jeanette Hellgren Kotalesk. Basal Ganglia Neuromodulation Over Multiple Temporal and Structural Scales-Simulations of Direct Pathway MSNs Investigate the Fast Onset of Dopaminergic Effects and Predict the Role of Kv4.2. Frontiers in neural circuits. vol 12. 2019-02-01. PMID:29467627. |
basal ganglia neuromodulation over multiple temporal and structural scales-simulations of direct pathway msns investigate the fast onset of dopaminergic effects and predict the role of kv4.2. |
2019-02-01 |
2023-08-13 |
Not clear |
| Robert Lindroos, Matthijs C Dorst, Kai Du, Marko Filipović, Daniel Keller, Maya Ketzef, Alexander K Kozlov, Arvind Kumar, Mikael Lindahl, Anu G Nair, Juan Pérez-Fernández, Sten Grillner, Gilad Silberberg, Jeanette Hellgren Kotalesk. Basal Ganglia Neuromodulation Over Multiple Temporal and Structural Scales-Simulations of Direct Pathway MSNs Investigate the Fast Onset of Dopaminergic Effects and Predict the Role of Kv4.2. Frontiers in neural circuits. vol 12. 2019-02-01. PMID:29467627. |
dopaminergic afferents from the midbrain and local cholinergic interneurons play crucial roles for basal ganglia function, and striatal signaling via the striosomes in turn regulates the midbrain dopaminergic system directly and via the lateral habenula. |
2019-02-01 |
2023-08-13 |
Not clear |
| Jae Woo Chung, Roxana G Burciu, Edward Ofori, Stephen A Coombes, Evangelos A Christou, Michael S Okun, Christopher W Hess, David E Vaillancour. Beta-band oscillations in the supplementary motor cortex are modulated by levodopa and associated with functional activity in the basal ganglia. NeuroImage. Clinical. vol 19. 2019-01-30. PMID:29984164. |
collectively, these findings provide the first direct evaluation of how movement-related cortical oscillations relate to movement velocity during the ballistic phase of movement in pd and demonstrate that functional brain activity in the basal ganglia pathways relate to the effects of dopaminergic medication on cortical neuronal oscillations during movement. |
2019-01-30 |
2023-08-13 |
Not clear |
| Tarık Acar, Gülsüm Alkan, Hüseyin Çaksen, Birsen Ertekin, Mehmet Ergin, Sedat Koçak, Başar Cande. Phenytoin induced dystonia. The Turkish journal of pediatrics. vol 60. issue 1. 2019-01-16. PMID:30102491. |
the abnormalities of dopaminergic activity in the basal ganglia have been emphasized to be effective in dystonia. |
2019-01-16 |
2023-08-13 |
Not clear |
| Rachel Rac-Lubashevsky, Heleen A Slagter, Yoav Kessle. Tracking Real-Time Changes in Working Memory Updating and Gating with the Event-Based Eye-Blink Rate. Scientific reports. vol 7. issue 1. 2018-12-14. PMID:28566762. |
these results may support the prefrontal cortex basal ganglia wm model (pbwm) by linking updating and gating to striatal dopaminergic activity. |
2018-12-14 |
2023-08-13 |
Not clear |
| Antonio Pedro Vargas, Francisco Eduardo Costa Cardos. Impulse control and related disorders in Parkinson's disease. Arquivos de neuro-psiquiatria. vol 76. issue 6. 2018-10-11. PMID:29972423. |
the pathophysiology of these disorders seems to be related to abnormal dopaminergic stimulation of the basal regions of the basal ganglia, especially via nigro-mesolimbic pathways. |
2018-10-11 |
2023-08-13 |
Not clear |
| Luigi Trojano, Costanza Papagn. Cognitive and behavioral disorders in Parkinson's disease: an update. II: behavioral disorders. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 39. issue 1. 2018-08-15. PMID:29038946. |
symptoms can be present since early stages of the disease, sometimes even before the appearance of classical motor symptoms, likely in relation to dopamine depletion in basal ganglia and/or to dysfunctions of other neurotrasmitter systems, and others can develop later, in some cases in relation to dopaminergic treatment. |
2018-08-15 |
2023-08-13 |
Not clear |
| Giuseppe Delvecchio, Alessandro Pigoni, Cinzia Perlini, Marco Barillari, Amelia Versace, Mirella Ruggeri, A Carlo Altamura, Marcella Bellani, Paolo Brambill. A diffusion weighted imaging study of basal ganglia in schizophrenia. International journal of psychiatry in clinical practice. vol 22. issue 1. 2018-08-13. PMID:28643537. |
basal ganglia are of particular interest, given not only the high concentration of dopaminergic neurons and receptors, but also for their crucial role in cognitive functions, commonly impaired in schizophrenia. |
2018-08-13 |
2023-08-13 |
Not clear |
| Teresa Mann, Jens Kurth, Alexander Hawlitschka, Jan Stenzel, Tobias Lindner, Stefan Polei, Alexander Hohn, Bernd J Krause, Andreas Wre. [ Molecules (Basel, Switzerland). vol 23. issue 3. 2018-08-13. PMID:29509680. |
the caudate-putamen (cpu), as the main input nucleus of the basal ganglia loop, is fundamentally involved in motor function and directly interacts with the dopaminergic system. |
2018-08-13 |
2023-08-13 |
rat |
| Natàlia Vilor-Tejedor, Alejandro Cáceres, Jesús Pujol, Jordi Sunyer, Juan R Gonzále. Imaging genetics in attention-deficit/hyperactivity disorder and related neurodevelopmental domains: state of the art. Brain imaging and behavior. vol 11. issue 6. 2018-07-09. PMID:27981420. |
we found that ig studies on adhd generally focus on dopaminergic genes and the structure of basal ganglia using structural magnetic resonance imaging (mri). |
2018-07-09 |
2023-08-13 |
Not clear |
| Franziska Wedekind, Angela Oskamp, Markus Lang, Alexander Hawlitschka, Karl Zilles, Andreas Wree, Andreas Baue. Intrastriatal administration of botulinum neurotoxin A normalizes striatal D Journal of neuroscience research. vol 96. issue 1. 2018-06-22. PMID:28695985. |
since the dopaminergic system of the basal ganglia fundamentally contributes to motor function, we investigated the impact of bont-a on striatal dopamine receptor expression using in vitro and in vivo imaging techniques (positron emission tomography and quantitative autoradiography, respectively). |
2018-06-22 |
2023-08-13 |
rat |
| Zoe Woodward, Timothy C R Prickett, Eric A Espiner, Timothy J Anderso. Central and systemic C-type Natriuretic Peptide are both reduced in Parkinson's Disease. Parkinsonism & related disorders. vol 43. 2018-06-12. PMID:28673612. |
c-type natriuretic peptide is a neuropeptide widely expressed in the central nervous system including dopaminergic neurons projecting to basal ganglia. |
2018-06-12 |
2023-08-13 |
human |
| Regina Rumpel, Mesbah Alam, Lisa M Schwarz, Andreas Ratzka, Xingxing Jin, Joachim K Krauss, Claudia Grothe, Kerstin Schwab. Neuronal firing activity in the basal ganglia after striatal transplantation of dopamine neurons in hemiparkinsonian rats. Neuroscience. vol 360. 2018-06-05. PMID:28790019. |
the loss of nigral dopaminergic neurons and the resulting dopamine (da) depletion in the striatum (str) lead to altered neuronal activity and enhanced beta activity in various regions of the basal ganglia (bg) motor loop in patients with parkinson's disease and in rodents in the 6-hydroxydopamine (6-ohda)-lesioned rat model. |
2018-06-05 |
2023-08-13 |
human |
| Agata Budzillo, Alison Duffy, Kimberly E Miller, Adrienne L Fairhall, David J Perke. Dopaminergic modulation of basal ganglia output through coupled excitation-inhibition. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 22. 2018-05-15. PMID:28507134. |
dopaminergic modulation of basal ganglia output through coupled excitation-inhibition. |
2018-05-15 |
2023-08-13 |
Not clear |
| Hitomi Aono, Mohammed Emamussalehin Choudhury, Hiromi Higaki, Kazuya Miyanishi, Yuka Kigami, Kohdai Fujita, Jun-Ichi Akiyama, Hisaaki Takahashi, Hajime Yano, Madoka Kubo, Noriko Nishikawa, Masahiro Nomoto, Junya Tanak. Microglia may compensate for dopaminergic neuron loss in experimental Parkinsonism through selective elimination of glutamatergic synapses from the subthalamic nucleus. Glia. vol 65. issue 11. 2018-05-14. PMID:28836295. |
thus, microglia may be involved in a negative feedback loop in the indirect pathway of the basal ganglia to compensate for the loss of dopaminergic neurons in pd brains. |
2018-05-14 |
2023-08-13 |
rat |