| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sangyep Shin, Andrea Santi, Shiyong Huan. Conditional Pten knockout in parvalbumin- or somatostatin-positive neurons sufficiently leads to autism-related behavioral phenotypes. Molecular brain. vol 14. issue 1. 2021-09-01. PMID:33504340. |
we examined asd-related behaviors in mice with conditional pten knockout in parvalbumin (pv)-expressing or somatostatin (sst)-expressing neurons, two common subtypes of gabaergic neurons. |
2021-09-01 |
2023-08-13 |
mouse |
| Natascha Ihbe, Florie Le Prieult, Qi Wang, Ute Distler, Malte Sielaff, Stefan Tenzer, Serge C Thal, Thomas Mittman. Adaptive Mechanisms of Somatostatin-Positive Interneurons after Traumatic Brain Injury through a Switch of α Subunits in L-Type Voltage-Gated Calcium Channels. Cerebral cortex (New York, N.Y. : 1991). 2021-08-19. PMID:34411234. |
this study investigated the role of gabaergic, somatostatin-positive (sst) interneurons in the contralateral hemisphere 72 h after unilateral tbi. |
2021-08-19 |
2023-08-13 |
mouse |
| Sha-Sha Yang, Nancy R Mack, Yousheng Shu, Wen-Jun Ga. Prefrontal GABAergic Interneurons Gate Long-Range Afferents to Regulate Prefrontal Cortex-Associated Complex Behaviors. Frontiers in neural circuits. vol 15. 2021-08-09. PMID:34322002. |
specifically, we first summarize the anatomical connections of different long-range inputs formed on prefrontal gabaergic ins, focusing on pv versus sst cells. |
2021-08-09 |
2023-08-13 |
Not clear |
| Seungjoon Kim, Dongseok Park, Jinhu Kim, Dongwook Kim, Hyeonho Kim, Takuma Mori, Hyeji Jung, Dongsu Lee, Sookyung Hong, Jongcheol Jeon, Katsuhiko Tabuchi, Eunji Cheong, Jaehoon Kim, Ji Won Um, Jaewon K. Npas4 regulates IQSEC3 expression in hippocampal somatostatin interneurons to mediate anxiety-like behavior. Cell reports. vol 36. issue 3. 2021-07-21. PMID:34289353. |
neuronal activation by an enriched environment induces npas4-mediated upregulation of iqsec3 protein specifically in ca1 stratum oriens layer somatostatin (sst)-expressing gabaergic interneurons. |
2021-07-21 |
2023-08-13 |
Not clear |
| Robert Lund. Comparison of GABA, Somatostatin, and Corticotrophin-Releasing Hormone Expression in Axon Terminals That Target the Parabrachial Nucleus. Chemical senses. vol 45. issue 4. 2021-05-25. PMID:32107535. |
together, the present results suggest that cea neurons marked by sst expression represent a major extrinsic source of gabaergic input to the pbn and this could underlie the predominate inhibitory effect of cea stimulation on taste-evoked responses in the pbn. |
2021-05-25 |
2023-08-13 |
mouse |
| Sarah J Jefferson, Mengyang Feng, URee Chon, Yao Guo, Yongsoo Kim, Bernhard Lusche. Disinhibition of somatostatin interneurons confers resilience to stress in male but not female mice. Neurobiology of stress. vol 13. 2021-05-14. PMID:33344694. |
disinhibition of somatostatin (sst)-positive gabaergic interneurons in mice by deletion of γ2 gaba |
2021-05-14 |
2023-08-13 |
mouse |
| Britt Mossink, Jon-Ruben van Rhijn, Shan Wang, Katrin Linda, Maria R Vitale, Johanna E M Zöller, Eline J H van Hugte, Jitske Bak, Anouk H A Verboven, Martijn Selten, Moritz Negwer, Brooke L Latour, Ilse van der Werf, Jason M Keller, Teun M Klein Gunnewiek, Chantal Schoenmaker, Astrid Oudakker, Alessia Anania, Sophie Jansen, Klaus-Peter Lesch, Monica Frega, Hans van Bokhoven, Dirk Schubert, Nael Nadif Kasr. Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks. Molecular psychiatry. 2021-05-11. PMID:33972691. |
cdh13 localizes at inhibitory presynapses, specifically of parvalbumin (pv) and somatostatin (sst) expressing gabaergic neurons. |
2021-05-11 |
2023-08-13 |
human |
| Britt Mossink, Jon-Ruben van Rhijn, Shan Wang, Katrin Linda, Maria R Vitale, Johanna E M Zöller, Eline J H van Hugte, Jitske Bak, Anouk H A Verboven, Martijn Selten, Moritz Negwer, Brooke L Latour, Ilse van der Werf, Jason M Keller, Teun M Klein Gunnewiek, Chantal Schoenmaker, Astrid Oudakker, Alessia Anania, Sophie Jansen, Klaus-Peter Lesch, Monica Frega, Hans van Bokhoven, Dirk Schubert, Nael Nadif Kasr. Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks. Molecular psychiatry. 2021-05-11. PMID:33972691. |
starting from human-induced pluripotent stem cells, we established a robust method to generate a homogenous population of sst and mef2c (pv-precursor marker protein) expressing gabaergic neurons (igaba) in vitro, and co-cultured these with glutamatergic neurons at defined e/i ratios on micro-electrode arrays. |
2021-05-11 |
2023-08-13 |
human |
| Giovanni Provenzano, Angela Gilardoni, Marika Maggia, Mattia Pernigo, Paola Sgadò, Simona Casarosa, Yuri Bozz. Altered Expression of GABAergic Markers in the Forebrain of Young and Adult Genes. vol 11. issue 4. 2021-03-26. PMID:32244845. |
we previously showed a reduced expression of gabaergic interneuron markers parvalbumin (pv) and somatostatin (sst) in the forebrain of adult mice lacking the |
2021-03-26 |
2023-08-13 |
mouse |
| Christine L Remmers, Charlotte C M Castillon, John N Armstrong, Anis Contracto. Recruitment of parvalbumin and somatostatin interneuron inputs to adult born dentate granule neurons. Scientific reports. vol 10. issue 1. 2021-03-10. PMID:33067500. |
this demonstrates that gabaergic innervation to abdgcs develops during a prolonged post-mitotic period and running scales both sst and pv synaptic afferents. |
2021-03-10 |
2023-08-13 |
mouse |
| Seungjoon Kim, Hyeonho Kim, Dongseok Park, Jinhu Kim, Joohyeon Hong, Jae Seong Kim, Hyeji Jung, Dongwook Kim, Eunji Cheong, Jaewon Ko, Ji Won U. Loss of IQSEC3 Disrupts GABAergic Synapse Maintenance and Decreases Somatostatin Expression in the Hippocampus. Cell reports. vol 30. issue 6. 2021-03-08. PMID:32049026. |
strikingly, selective introduction of sst into sst interneurons in dg-specific iqsec3-kd mice reverses gabaergic synaptic deficits. |
2021-03-08 |
2023-08-13 |
mouse |
| Elina Nagaeva, Ivan Zubarev, Carolina Bengtsson Gonzales, Mikko Forss, Kasra Nikouei, Elena de Miguel, Lauri Elsilä, Anni-Maija Linden, Jens Hjerling-Leffler, George J Augustine, Esa R Korp. Heterogeneous somatostatin-expressing neuron population in mouse ventral tegmental area. eLife. vol 9. 2021-02-18. PMID:32749220. |
importantly, similar to cortical sst-containing interneurons, most vta sst neurons express gabaergic inhibitory markers, but some of them also express glutamatergic excitatory markers and a subpopulation even express dopaminergic markers. |
2021-02-18 |
2023-08-13 |
mouse |
| Jianmin Su, Danielle Basso, Shivani Iyer, Kaiwen Su, Jessica Wei, Michael A Fo. Paracrine Role for Somatostatin Interneurons in the Assembly of Perisomatic Inhibitory Synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 39. 2021-01-15. PMID:32847968. |
two abundant populations of cortical gabaergic interneurons include the low-threshold, somatostatin (sst)-expressing cells and the fast-spiking, parvalbumin (pv)-expressing cells. |
2021-01-15 |
2023-08-13 |
Not clear |
| Ulrich Pfisterer, Viktor Petukhov, Samuel Demharter, Johanna Meichsner, Jonatan J Thompson, Mykhailo Y Batiuk, Andrea Asenjo-Martinez, Navneet A Vasistha, Ashish Thakur, Jens Mikkelsen, Istvan Adorjan, Lars H Pinborg, Tune H Pers, Jakob von Engelhardt, Peter V Kharchenko, Konstantin Khodosevic. Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis. Nature communications. vol 11. issue 1. 2020-10-27. PMID:33028830. |
we found that the largest transcriptomic changes occur in distinct neuronal subtypes from several families of principal neurons (l5-6_fezf2 and l2-3_cux2) and gabaergic interneurons (sst and pvalb), whereas other subtypes in the same families were less affected. |
2020-10-27 |
2023-08-13 |
human |
| Na Clara Pan, Ai Fang, Chen Shen, Le Sun, Qian Wu, Xiaoqun Wan. Early Excitatory Activity-Dependent Maturation of Somatostatin Interneurons in Cortical Layer 2/3 of Mice. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 10. 2020-10-13. PMID:30535288. |
among the diverse gabaergic neurons present in the brain, early-born somatostatin (sst)-expressing inhibitory interneurons, which are innervated by other interneurons and local pyramidal cells (pcs), act in a neural computational role in circuitry regulation. |
2020-10-13 |
2023-08-13 |
mouse |
| Siouar Bensaid, Julien Modolo, Isabelle Merlet, Fabrice Wendling, Pascal Benque. COALIA: A Computational Model of Human EEG for Consciousness Research. Frontiers in systems neuroscience. vol 13. 2020-09-28. PMID:31798421. |
using the model, it is possible to reproduce the local disynaptic disinhibition of basket cells (fast gabaergic inhibition) and glutamatergic pyramidal neurons through long-range activation of vasoactive intestinal-peptide (vip) interneurons that induced inhibition of somatostatin positive (sst) interneurons. |
2020-09-28 |
2023-08-13 |
human |
| Daniel Saiz-Sanchez, Isabel Ubeda-Bañon, Alicia Flores-Cuadrado, Melania Gonzalez-Rodriguez, Sandra Villar-Conde, Veronica Astillero-Lopez, Alino Martinez-Marco. Somatostatin, Olfaction, and Neurodegeneration. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32140092. |
sst is a neuropeptide present in a subpopulation of gabaergic interneurons throughout the brain and its main function is to inhibit principal neurons and/or other interneurons. |
2020-09-28 |
2023-08-13 |
Not clear |
| Nigel C Dao, Malini Suresh Nair, Sarah N Magee, J Brody Moyer, Veronica Sendao, Dakota F Brockway, Nicole A Crowle. Forced Abstinence From Alcohol Induces Sex-Specific Depression-Like Behavioral and Neural Adaptations in Somatostatin Neurons in Cortical and Amygdalar Regions. Frontiers in behavioral neuroscience. vol 14. 2020-09-28. PMID:32536856. |
somatostatin (sst) neurons, a subtype of gabaergic neurons found throughout the brain, are a novel neural target with potential treatment implications in affective disorders, yet their role in alcohol use disorders (aud) remains to be explored. |
2020-09-28 |
2023-08-13 |
mouse |
| You-Hyang Song, Yang-Sun Hwang, Kwansoo Kim, Hyoung-Ro Lee, Jae-Hyun Kim, Catherine Maclachlan, Anaelle Dubois, Min Whan Jung, Carl C H Petersen, Graham Knott, Suk-Ho Lee, Seung-Hee Le. Somatostatin enhances visual processing and perception by suppressing excitatory inputs to parvalbumin-positive interneurons in V1. Science advances. vol 6. issue 17. 2020-06-06. PMID:32494634. |
somatostatin (sst) is a neuropeptide expressed in a major subtype of gabaergic interneurons in the cortex. |
2020-06-06 |
2023-08-13 |
mouse |
| Ryan J Duchatel, Lauren R Harms, Crystal L Meehan, Patricia T Michie, Mark J Bigland, Doug W Smith, Phillip Jobling, Deborah M Hodgson, Paul A Toone. Reduced cortical somatostatin gene expression in a rat model of maternal immune activation. Psychiatry research. vol 282. 2020-05-05. PMID:31648143. |
this suggests that our model of maternal immune activation induced by prenatal exposure of rats to polyinosinic:polycytidylic acid during late gestation is able to recapitulate changes in sst but not other gabaergic neuropathologies observed in schizophrenia. |
2020-05-05 |
2023-08-13 |
rat |