| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chizuru Iwasawa, Naoko Kuzumaki, Yukari Suda, Reiko Kagawa, Yuko Oka, Nobutaka Hattori, Hideyuki Okano, Minoru Narit. Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations. Molecular brain. vol 12. issue 1. 2019-06-10. PMID:30658665. |
somatostatin (sst) is considered to be a modulator of gabaergic inhibitory transmission, and its levels are reduced in cerebrospinal fluid of pd patients. |
2019-06-10 |
2023-08-13 |
Not clear |
| Chizuru Iwasawa, Naoko Kuzumaki, Yukari Suda, Reiko Kagawa, Yuko Oka, Nobutaka Hattori, Hideyuki Okano, Minoru Narit. Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations. Molecular brain. vol 12. issue 1. 2019-06-10. PMID:30658665. |
in the present study, we evaluated the changes in the expression of sst in gabaergic neurons derived from induced pluripotent stem cells (ipscs) of pd patients. |
2019-06-10 |
2023-08-13 |
Not clear |
| Chizuru Iwasawa, Naoko Kuzumaki, Yukari Suda, Reiko Kagawa, Yuko Oka, Nobutaka Hattori, Hideyuki Okano, Minoru Narit. Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations. Molecular brain. vol 12. issue 1. 2019-06-10. PMID:30658665. |
under this condition, the mrna level of sst in gabaergic interneurons derived from ipscs of park2-specific pd patients significantly decreased as neural maturation progressed. |
2019-06-10 |
2023-08-13 |
Not clear |
| Chizuru Iwasawa, Naoko Kuzumaki, Yukari Suda, Reiko Kagawa, Yuko Oka, Nobutaka Hattori, Hideyuki Okano, Minoru Narit. Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations. Molecular brain. vol 12. issue 1. 2019-06-10. PMID:30658665. |
these findings suggest that the reduction in the expression level of sst in gabaergic interneurons of pd may, at least partly, lead to complex pd-induced symptoms. |
2019-06-10 |
2023-08-13 |
Not clear |
| X Du, K Serena, Wu Jeong Hwang, A M Grech, Y W C Wu, A Schroeder, R A Hil. Prefrontal cortical parvalbumin and somatostatin expression and cell density increase during adolescence and are modified by BDNF and sex. Molecular and cellular neurosciences. vol 88. 2019-01-31. PMID:29408239. |
here, we performed a week-by-week analysis of the protein expression and cell density of three major gabaergic interneurons, parvalbumin (pv), somatostatin (sst) and calretinin (cal) in the medial prefrontal cortex from prepubescence (week 3) to adulthood (week 12). |
2019-01-31 |
2023-08-13 |
mouse |
| Wei-Qing Hou, Pei-Pei Liu, Xue-Ying Wang, Lan Ma, Fei-Fei Wan. [Somatostatin interneurons of prelimbic cortex in regulating morphine-induced behavior changes]. Sheng li xue bao : [Acta physiologica Sinica]. vol 70. issue 5. 2019-01-08. PMID:30377684. |
in the prl, parvalbumin (pv) and somatostatin (sst) interneurons are two major gabaergic interneurons, which have been reported to regulate the activity of glutamatergic input, and form inhibitory synaptic transmission to regulate the output of downstream signals. |
2019-01-08 |
2023-08-13 |
mouse |
| Keita Fukumoto, Kota Tamada, Tsuyoshi Toya, Tasuku Nishino, Yuchio Yanagawa, Toru Takum. Identification of genes regulating GABAergic interneuron maturation. Neuroscience research. vol 134. 2018-11-01. PMID:29203264. |
correlational analysis revealed that dgkg is dominantly expressed in somatostatin (sst)-expressing gabaergic interneurons. |
2018-11-01 |
2023-08-13 |
Not clear |
| Daniel C Javitt, Migyung Lee, Joshua T Kantrowitz, Antigona Martine. Mismatch negativity as a biomarker of theta band oscillatory dysfunction in schizophrenia. Schizophrenia research. vol 191. 2018-10-30. PMID:28666633. |
mmn reflects activity primarily in theta (4-7hz) frequency band, which is thought to depend primarily upon interplay between cortical pyramidal neurons and somatostatin (sst)-type local circuit gabaergic interneurons. |
2018-10-30 |
2023-08-13 |
Not clear |
| Sarah Xinwei Luo, Ju Huang, Qin Li, Hasan Mohammad, Chun-Yao Lee, Kumar Krishna, Alison Maun-Yeng Kok, Yu Lin Tan, Joy Yi Lim, Hongyu Li, Ling Yun Yeow, Jingjing Sun, Miao He, Joanes Grandjean, Sreedharan Sajikumar, Weiping Han, Yu F. Regulation of feeding by somatostatin neurons in the tuberal nucleus. Science (New York, N.Y.). vol 361. issue 6397. 2018-08-03. PMID:29976824. |
gabaergic tuberal sst ( |
2018-08-03 |
2023-08-13 |
mouse |
| Corey Fee, Mounira Banasr, Etienne Sibill. Somatostatin-Positive Gamma-Aminobutyric Acid Interneuron Deficits in Depression: Cortical Microcircuit and Therapeutic Perspectives. Biological psychiatry. vol 82. issue 8. 2018-05-21. PMID:28697889. |
in mdd, recent evidence from human postmortem and animal studies suggests a selective vulnerability of gabaergic interneurons that coexpress the neuropeptide somatostatin (sst). |
2018-05-21 |
2023-08-13 |
human |
| William Muñoz, Robin Tremblay, Daniel Levenstein, Bernardo Rud. Layer-specific modulation of neocortical dendritic inhibition during active wakefulness. Science (New York, N.Y.). vol 355. issue 6328. 2017-10-31. PMID:28254942. |
using an optical-tagging electrophysiological approach to record and label somatostatin-expressing (sst) interneurons (gabaergic neurons specialized for dendritic inhibition), we discovered a layer-specific modulation of their activity in behaving mice. |
2017-10-31 |
2023-08-13 |
mouse |
| Guillaume Osterstock, Violeta Mitutsova, Alexander Barre, Manon Granier, Pierre Fontanaud, Marine Chazalon, Danielle Carmignac, Iain C A F Robinson, Malcolm J Low, Nikolaus Plesnila, David J Hodson, Patrice Mollard, Pierre-François Mér. Somatostatin triggers rhythmic electrical firing in hypothalamic GHRH neurons. Scientific reports. vol 6. 2017-04-04. PMID:27072430. |
the oscillation patterns induced by sst were sexually dimorphic, and could be explained by differential actions of sst on both gabaergic and glutamatergic currents. |
2017-04-04 |
2023-08-13 |
mouse |
| Aurélie Pala, Carl C H Peterse. In vivo measurement of cell-type-specific synaptic connectivity and synaptic transmission in layer 2/3 mouse barrel cortex. Neuron. vol 85. issue 1. 2015-05-01. PMID:25543458. |
we found that parvalbumin-expressing (pv) gabaergic neurons received unitary glutamatergic synaptic input with higher probability than somatostatin-expressing (sst) gabaergic neurons. |
2015-05-01 |
2023-08-13 |
mouse |
| Yunshuo Tang, Michael P Stryker, Arturo Alvarez-Buylla, Juan Sebastian Espinos. Cortical plasticity induced by transplantation of embryonic somatostatin or parvalbumin interneurons. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 51. 2015-04-17. PMID:25489113. |
we recently have shown that transplantation of gabaergic precursors from the embryonic medial ganglionic eminence (mge), the source of neocortical parvalbumin- (pv(+)) and somatostatin-expressing (sst(+)) interneurons, can induce a new period of ocular dominance plasticity (odp) after the endogenous period has closed. |
2015-04-17 |
2023-08-13 |
Not clear |
| Y Liu, X Liang, W-W Ren, B-M L. Expression of β1- and β2-adrenoceptors in different subtypes of interneurons in the medial prefrontal cortex of mice. Neuroscience. vol 257. 2014-08-26. PMID:24215978. |
here, we report that both β1- and β2-ars are expressed in a majority of gabaergic interneurons in the medial prefrontal cortex of mice, including parvalbumin (pv)-, calretinin (cr)-, calbindin d-28k (cb)-, somatostatin (sst)- and reelin-immunoreactive (ir) interneurons. |
2014-08-26 |
2023-08-12 |
mouse |
| Masayuki Takahashi, Mamoru Takeda, Shigeji Matsumot. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain research bulletin. vol 100. 2014-08-22. PMID:24321530. |
the aim of the present study was to investigate whether iontophoretic application of sst facilitates the excitability of nociceptive upper cervical spinal dorsal horn (c1) neurons through gabaergic disinhibiton, using extracellular electrophysiological recording with multibarrel electrodes and immunohistochemical techniques. |
2014-08-22 |
2023-08-12 |
rat |
| Masayuki Takahashi, Mamoru Takeda, Shigeji Matsumot. Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons. Brain research bulletin. vol 100. 2014-08-22. PMID:24321530. |
these results suggest that a local release of sst facilitates the excitability of trigeminal nocicepitve c1 neuronal activity via inhibition of gabaergic neurons. |
2014-08-22 |
2023-08-12 |
rat |
| Violeta G López-Huerta, Eduardo Blanco-Hernández, José Bargas, Elvira Galarrag. Presynaptic modulation by somatostatin in the rat neostriatum is altered in a model of parkinsonism. Journal of neurophysiology. vol 108. issue 4. 2013-06-11. PMID:22623487. |
somatostatin (sst) is a peptide synthesized and released by a class of neostriatal local gabaergic interneurons, which, to some extent, are in charge of the feedforward inhibitory circuit. |
2013-06-11 |
2023-08-12 |
rat |
| Hanieh Toossi, Esther Del Cid-Pellitero, Thomas Stroh, Barbara E Jone. Somatostatin varicosities contain the vesicular GABA transporter and contact orexin neurons in the hypothalamus. The European journal of neuroscience. vol 36. issue 10. 2013-04-29. PMID:22925106. |
in triple-immunostained sections viewed by epifluorescence and confocal microscopy, sst varicosities were seen in contact with orexin somata, and of these varicosities, a significant proportion (23%) contained vgat along with synaptophysin, the presynaptic marker for small synaptic vesicles, and a similar proportion (25%) abutted puncta that were immunostained for gephyrin, the postsynaptic marker for gabaergic synapses. |
2013-04-29 |
2023-08-12 |
rat |
| Xavier H Jaglin, Jens Hjerling-Leffler, Gord Fishell, Renata Batista-Brit. The origin of neocortical nitric oxide synthase-expressing inhibitory neurons. Frontiers in neural circuits. vol 6. 2012-10-02. PMID:22787442. |
finally, we show that conditional removal of the transcription factor sox6 in mge-derived gabaergic cortical neurons results in an absence of sst and cr expression, as well as reduced expression of nnos in neocortical nnos neurons. |
2012-10-02 |
2023-08-12 |
Not clear |