| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoxiang Xu, Jun Liu, Zixuan Xiao, Shuang Li, Ya Zhang, Peng Song, Kun Lin, Lei Zhang, Haoquan Zheng, Yuye Zhou, Xiong Che. Zeolitic imidazolate framework-90 loaded with methylprednisolone sodium succinate effectively reduces hypertrophic scar Nanoscale. 2024-03-15. PMID:38488127. |
mpss@zif-90 enhanced the apoptosis of human hypertrophic scar fibroblasts and downregulated the overexpression of tgf-β1, vegf, α-sma, and collagen i/iii both |
2024-03-15 |
2024-03-17 |
human |
| Zuzana Amlerova, Martina Chmelova, Miroslava Anderova, Lydia Vargov. Reactive gliosis in traumatic brain injury: a comprehensive review. Frontiers in cellular neuroscience. vol 18. 2024-03-14. PMID:38481632. |
the critical components contributing to cns response, damage control, and regeneration after tbi are glial cells-in reaction to tissue damage, their activation, hypertrophy, and proliferation occur, followed by the formation of a glial scar. |
2024-03-14 |
2024-03-16 |
Not clear |
| Honghao Yu, Heting Feng, Hong Zeng, Yiping Wu, Qi Zhang, Jing Yu, Kai Hou, Min W. Exosomes: The emerging mechanisms and potential clinical applications in dermatology. International journal of biological sciences. vol 20. issue 5. 2024-03-14. PMID:38481799. |
in this review, we mainly summarize the latest studies about the mechanisms and applications of exosomes in dermatology, including psoriasis, atopic dermatitis, vitiligo, systemic lupus erythematosus, systemic sclerosis, diabetic wound healing, hypertrophic scar and keloid, and skin aging. |
2024-03-14 |
2024-03-16 |
human |
| Li Lin-Hui, Zha Yuan-Yuan, Liu Ming-Yu, Hong Xu-Dong, Ding Yin-Jia, Zhou Yue, Fei Yang-Hong-Hong, Chen Ai-Fen, Zhang Xu-Dong, Chen Zheng-Li, Jin Jia. Recombinant Human Collagen Type III Improves Hypertrophic Scarring by Regulating the Ratio of Type I/III Collagen. Journal of burn care & research : official publication of the American Burn Association. 2024-03-13. PMID:38477626. |
hypertrophic scar development is a complication associated with wound healing, impacting local appearance and function. |
2024-03-13 |
2024-03-15 |
human |
| Keqing Qiu, Yan Tian, Chunyan Guo, Ougen Liu, Yan Shi, Dewu Liu, Tao Lu. Global proteomic analysis reveals lysine succinylation is involved in the pathogenesis of hypertrophic scar. Journal of proteomics. 2024-03-09. PMID:38460743. |
global proteomic analysis reveals lysine succinylation is involved in the pathogenesis of hypertrophic scar. |
2024-03-09 |
2024-03-12 |
human |
| Keqing Qiu, Yan Tian, Chunyan Guo, Ougen Liu, Yan Shi, Dewu Liu, Tao Lu. Global proteomic analysis reveals lysine succinylation is involved in the pathogenesis of hypertrophic scar. Journal of proteomics. 2024-03-09. PMID:38460743. |
this study examined the role of ksucc in the pathogenesis of hypertrophic scar (hs). |
2024-03-09 |
2024-03-12 |
human |
| Parisa Moori, Laura Cappuyns, Kayvan Shokrollah. Carbon dioxide laser for precise and bloodless contouring of soft tissue ahead of skin grafting-A case example of technique and benefits. JPRAS open. vol 40. 2024-03-06. PMID:38444628. |
post-burn scars are often hypertrophic in nature and thus exhibit a much thicker and firmer scar, often leading to contractures. |
2024-03-06 |
2024-03-08 |
Not clear |
| Zhuo-Ran Yang, Huinan Suo, Jing-Wen Fan, Niannian Lv, Kehan Du, Teng Ma, Huimin Qin, Yan Li, Liu Yang, Nuoya Zhou, Hao Jiang, Juan Tao, Jintao Zh. Endogenous stimuli-responsive separating microneedles to inhibit hypertrophic scar through remodeling the pathological microenvironment. Nature communications. vol 15. issue 1. 2024-03-06. PMID:38448448. |
endogenous stimuli-responsive separating microneedles to inhibit hypertrophic scar through remodeling the pathological microenvironment. |
2024-03-06 |
2024-03-09 |
mouse |
| Zhuo-Ran Yang, Huinan Suo, Jing-Wen Fan, Niannian Lv, Kehan Du, Teng Ma, Huimin Qin, Yan Li, Liu Yang, Nuoya Zhou, Hao Jiang, Juan Tao, Jintao Zh. Endogenous stimuli-responsive separating microneedles to inhibit hypertrophic scar through remodeling the pathological microenvironment. Nature communications. vol 15. issue 1. 2024-03-06. PMID:38448448. |
hypertrophic scar (hs) considerably affects the appearance and causes tissue dysfunction in patients. |
2024-03-06 |
2024-03-09 |
mouse |
| Yaxin Tan, Mengde Zhang, Yi Kong, Fanliang Zhang, Yuzhen Wang, Yuyan Huang, Wei Song, Zhao Li, Linhao Hou, Liting Liang, Xu Guo, Qinghua Liu, Yu Feng, Chao Zhang, Xiaobing Fu, Sha Huan. Fibroblasts and endothelial cells interplay drives hypertrophic scar formation: Insights from in vitro and in vivo models. Bioengineering & translational medicine. vol 9. issue 2. 2024-03-04. PMID:38435816. |
fibroblasts and endothelial cells interplay drives hypertrophic scar formation: insights from in vitro and in vivo models. |
2024-03-04 |
2024-03-06 |
Not clear |
| Yaxin Tan, Mengde Zhang, Yi Kong, Fanliang Zhang, Yuzhen Wang, Yuyan Huang, Wei Song, Zhao Li, Linhao Hou, Liting Liang, Xu Guo, Qinghua Liu, Yu Feng, Chao Zhang, Xiaobing Fu, Sha Huan. Fibroblasts and endothelial cells interplay drives hypertrophic scar formation: Insights from in vitro and in vivo models. Bioengineering & translational medicine. vol 9. issue 2. 2024-03-04. PMID:38435816. |
hypertrophic scar formation is influenced by the intricate interplay between fibroblasts and endothelial cells. |
2024-03-04 |
2024-03-06 |
Not clear |
| Anna Szabó, Ignace De Decker, Sam Semey, Karel E Y Claes, Phillip Blondeel, Stan Monstrey, Jo Van Dorpe, Sandra Van Vlierbergh. Photo-crosslinkable polyester microneedles as sustained drug release systems toward hypertrophic scar treatment. Drug delivery. vol 31. issue 1. 2024-03-01. PMID:38424728. |
photo-crosslinkable polyester microneedles as sustained drug release systems toward hypertrophic scar treatment. |
2024-03-01 |
2024-03-03 |
Not clear |
| Yong Du, Jing Liu, Qing Hao, Shun Wang, Aijun Zhang, Yongzhong Li, Ninghan Fen. Effects of miR-214 on adenosine A2A receptor and carboxymethyl chitosan nanoparticles on the function of keloid fibroblasts and their mechanisms. Scientific reports. vol 14. issue 1. 2024-02-28. PMID:38418830. |
changes in the expression levels of mir-214 and a2ar in kfbs, normal skin fibroblasts (nfbs), hypertrophic scar tissue, and normal skin tissue were analyzed. |
2024-02-28 |
2024-03-02 |
Not clear |
| Yong Du, Jing Liu, Qing Hao, Shun Wang, Aijun Zhang, Yongzhong Li, Ninghan Fen. Effects of miR-214 on adenosine A2A receptor and carboxymethyl chitosan nanoparticles on the function of keloid fibroblasts and their mechanisms. Scientific reports. vol 14. issue 1. 2024-02-28. PMID:38418830. |
the mrna levels of mir-214 in kfbs and hypertrophic scar tissue were lower than those in nfbs and normal tissue (p < 0.001), while the mrna and protein levels of a2ar were significantly elevated (p < 0.05). |
2024-02-28 |
2024-03-02 |
Not clear |
| Hojin Park, Yijun Moon, Da Som Kim, Seung Ha Par. Medial Epicanthal Fold Correction Using a Y-W Epicanthoplasty in Asian Eyelids. The Journal of craniofacial surgery. 2024-02-27. PMID:38411191. |
one patient had a hypertrophic scar that was successfully managed with triamcinolone acetonide injections. |
2024-02-27 |
2024-03-02 |
Not clear |
| Junya Kusumoto, Masaya Akashi, Hiroto Terashi, Shunsuke Sakakibar. Differential Photosensitivity of Fibroblasts Obtained from Normal Skin and Hypertrophic Scar Tissues. International journal of molecular sciences. vol 25. issue 4. 2024-02-24. PMID:38396801. |
differential photosensitivity of fibroblasts obtained from normal skin and hypertrophic scar tissues. |
2024-02-24 |
2024-02-26 |
human |
| Junya Kusumoto, Masaya Akashi, Hiroto Terashi, Shunsuke Sakakibar. Differential Photosensitivity of Fibroblasts Obtained from Normal Skin and Hypertrophic Scar Tissues. International journal of molecular sciences. vol 25. issue 4. 2024-02-24. PMID:38396801. |
the expression of opsins, which are photoreceptor proteins, in normal dermal fibroblasts (ndfs) and hypertrophic scar fibroblasts (hsfs) was examined. |
2024-02-24 |
2024-02-26 |
human |
| Zizheng Yang, Zhiguo Yang, Zongbao Zu. Early intervention of carbon dioxide fractional laser in hypertrophic scar through TGFβ-1/ Smad3 signaling pathway. Lasers in medical science. vol 39. issue 1. 2024-02-22. PMID:38388742. |
early intervention of carbon dioxide fractional laser in hypertrophic scar through tgfβ-1/ smad3 signaling pathway. |
2024-02-22 |
2024-02-25 |
rabbit |
| Zizheng Yang, Zhiguo Yang, Zongbao Zu. Early intervention of carbon dioxide fractional laser in hypertrophic scar through TGFβ-1/ Smad3 signaling pathway. Lasers in medical science. vol 39. issue 1. 2024-02-22. PMID:38388742. |
severe scarring affects interpersonal and social relationships, and decreases the quality of life of the patients.the aim of this study was to evaluate the effect of carbon dioxide fractional laser as an early intervention against hypertrophic scars using a rabbit ear scar model, and explore the role of the tgfβ-1/ smad3 signaling pathway in scar hyperplasia. |
2024-02-22 |
2024-02-25 |
rabbit |
| Josef Haik, Yehuda Ullmann, Eyal Gur, Erik Biros, Rachel Kornhaber, Michelle Cleary, Dani Kruchevsky, Sivan Zissman, Yossi Namir, Moti Harat. Spincare® System Demonstrates Safety and Efficacy in Treating Partial Thickness Burns. Journal of burn care & research : official publication of the American Burn Association. 2024-02-21. PMID:38381556. |
only one moderate adverse event was observed concerning the treatment, and it is important to acknowledge the potential progression of this hypertrophic scar into a keloid. |
2024-02-21 |
2024-02-24 |
Not clear |