| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zilu Qu, Yao Chen, Kun Du, JiaXi Qiao, Liuqing Chen, Jinbo Chen, Li We. ALA-PDT promotes the death and contractile capacity of hypertrophic scar fibroblasts through inhibiting the TGF-β1/Smad2/3/4 signaling pathway. Photodiagnosis and photodynamic therapy. vol 45. 2023-12-21. PMID:38128289. |
5-aminolevulinic acid-based photodynamic therapy (ala-pdt) is a promising therapy for hypertrophic scar, details of the mechanisms remain to be elucidated. |
2023-12-21 |
2023-12-24 |
Not clear |
| Zilu Qu, Yao Chen, Kun Du, JiaXi Qiao, Liuqing Chen, Jinbo Chen, Li We. ALA-PDT promotes the death and contractile capacity of hypertrophic scar fibroblasts through inhibiting the TGF-β1/Smad2/3/4 signaling pathway. Photodiagnosis and photodynamic therapy. vol 45. 2023-12-21. PMID:38128289. |
in this study, we aimed to investigate the molecular mechanisms involved in ala-pdt against hypertrophic scar fibroblasts. |
2023-12-21 |
2023-12-24 |
Not clear |
| Cláudia B A Medeiros, Iasmim Lopes de Lima, Thiago Barbosa Cahú, Bruna R Muniz, Maria Helena M L Ribeiro, Érico Higino de Carvalho, Marcos Nogueira Eberlin, Marcelo J B Miranda, Ranilson de Souza Bezerra, Roberto Afonso da Silva, José Luiz de Lima Filh. Performance of collagen-based matrices from Nile tilapia skin: A pilot proteomic study in a murine model of wound healing. Journal of mass spectrometry : JMS. vol 59. issue 1. 2023-12-19. PMID:38108530. |
full-thickness cutaneous trauma, due to the lack of dermis, leads to difficulty in epithelialization by keratinocytes, developing a fibrotic scar, with less elasticity than the original skin, which may have disorders in predisposed individuals, resulting in hypertrophic scar and keloids. |
2023-12-19 |
2023-12-21 |
Not clear |
| Takashi Ito, Toshiyuki Yamamot. Hypertrophic scar mimicking peristomal pyoderma gangrenosum. Anais brasileiros de dermatologia. 2023-12-15. PMID:38102049. |
hypertrophic scar mimicking peristomal pyoderma gangrenosum. |
2023-12-15 |
2023-12-18 |
Not clear |
| Peng Wang, Zhangwen Peng, Liu Yu, Yiling Liu, Hanwen Wang, Ziheng Zhou, Hengdeng Liu, Sheng Hong, Yichu Nie, Yang Deng, Yang Liu, Julin Xi. Verteporfin-Loaded Bioadhesive Nanoparticles for the Prevention of Hypertrophic Scar. Small methods. 2023-12-12. PMID:38084464. |
verteporfin-loaded bioadhesive nanoparticles for the prevention of hypertrophic scar. |
2023-12-12 |
2023-12-17 |
human |
| Peng Wang, Zhangwen Peng, Liu Yu, Yiling Liu, Hanwen Wang, Ziheng Zhou, Hengdeng Liu, Sheng Hong, Yichu Nie, Yang Deng, Yang Liu, Julin Xi. Verteporfin-Loaded Bioadhesive Nanoparticles for the Prevention of Hypertrophic Scar. Small methods. 2023-12-12. PMID:38084464. |
vp/bnps displayed significant inhibition on the proliferation, migration, collagen deposition, and vessel formation of human hypertrophic scar fibroblasts (hsfbs) and dermal vascular endothelial cells (hdvecs). |
2023-12-12 |
2023-12-17 |
human |
| Yunsheng Chen, Kun Chen, Shan Zhong, Jiaqiang Wang, Zhixi Yu, Xiyang Sun, Yue Wang, Yan Liu, Zheng Zhan. Transdermal Transfersome Nanogels Control Hypertrophic Scar Formation via Synergy of Macrophage Phenotype-Switching and Anti-Fibrosis Effect. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023-12-08. PMID:38064170. |
transdermal transfersome nanogels control hypertrophic scar formation via synergy of macrophage phenotype-switching and anti-fibrosis effect. |
2023-12-08 |
2023-12-17 |
Not clear |
| Yunsheng Chen, Kun Chen, Shan Zhong, Jiaqiang Wang, Zhixi Yu, Xiyang Sun, Yue Wang, Yan Liu, Zheng Zhan. Transdermal Transfersome Nanogels Control Hypertrophic Scar Formation via Synergy of Macrophage Phenotype-Switching and Anti-Fibrosis Effect. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023-12-08. PMID:38064170. |
hypertrophic scar (hs), which results from prolonged inflammation and excessive fibrosis in re-epithelialized wounds, is one of the most common clinical challenges. |
2023-12-08 |
2023-12-17 |
Not clear |
| Xixi Li, Zhipeng Huang, Hua Chao, Xunxun Li. The mechanism of Semen Persicae-Flos Carthami in treating hypertrophic scar: A study based on network pharmacological analysis and in vitro experiments. Chemical biology & drug design. 2023-12-06. PMID:38056934. |
the mechanism of semen persicae-flos carthami in treating hypertrophic scar: a study based on network pharmacological analysis and in vitro experiments. |
2023-12-06 |
2023-12-10 |
Not clear |
| Xixi Li, Zhipeng Huang, Hua Chao, Xunxun Li. The mechanism of Semen Persicae-Flos Carthami in treating hypertrophic scar: A study based on network pharmacological analysis and in vitro experiments. Chemical biology & drug design. 2023-12-06. PMID:38056934. |
traditional medicine believes that hypertrophic scar (hs) falls into the category of "blood stasis". |
2023-12-06 |
2023-12-10 |
Not clear |
| Xixi Li, Zhipeng Huang, Hua Chao, Xunxun Li. The mechanism of Semen Persicae-Flos Carthami in treating hypertrophic scar: A study based on network pharmacological analysis and in vitro experiments. Chemical biology & drug design. 2023-12-06. PMID:38056934. |
besides, a modified explant culture method was applied to separate primary hypertrophic scar fibroblasts (hsfs); mtt assay to detect cell viability of hsfs after treatment by sp-fc for 24 h; annexin v-fitc/pi double staining combined with flow cytometry to test apoptosis; western blot to check the protein expression level of p53; and real-time fluorescence quantitative pcr to determine mrna level of p53. |
2023-12-06 |
2023-12-10 |
Not clear |
| Huimin Zhang, Chengyu Zang, Wen Zhao, Linfeng Zhang, Rui Liu, Zhang Feng, Jie Wu, Rongtao Cu. Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway. International journal of nanomedicine. vol 18. 2023-12-04. PMID:38046235. |
exosome derived from mesenchymal stem cells alleviates hypertrophic scar by inhibiting the fibroblasts via tnfsf-13/hspg2 signaling pathway. |
2023-12-04 |
2023-12-10 |
Not clear |
| Huimin Zhang, Chengyu Zang, Wen Zhao, Linfeng Zhang, Rui Liu, Zhang Feng, Jie Wu, Rongtao Cu. Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway. International journal of nanomedicine. vol 18. 2023-12-04. PMID:38046235. |
the aim of this study is to investigate how tnfsf13 and hspg2 affect the formation of hypertrophic scar (hs) and the mechanism by which exosomes regulate hs. |
2023-12-04 |
2023-12-10 |
Not clear |
| Yefei Zhang, Jiahui Chen, Jia Tian, Yehui Zhou, Yan Li. Role and function of plakophilin 3 in cancer progression and skin disease. Cancer science. 2023-12-04. PMID:38048779. |
as pkp3 is mostly expressed in the skin, loss of pkp3 promotes the development of several skin diseases, such as paraneoplastic pemphigus, pemphigus vulgaris, and hypertrophic scar. |
2023-12-04 |
2023-12-10 |
human |
| Lam Van Nguyen, Huy Quang Ly, Hau Thi Vo, Thao Thanh Pham, Nam Ky Nguyen, Thi Van Vo, Trung Quoc Phan, Phuong Thi Ngoc Tran, Hung Huynh Vinh Ly, Ha Thi Thao Ma. Clinical Features and the Outcome Evaluations of Keloid and Hypertrophic Scar Treatment with Triamcinolone Injection in Mekong Delta, Vietnam - A Cross-Sectional Study. Clinical, cosmetic and investigational dermatology. vol 16. 2023-12-01. PMID:38021426. |
clinical features and the outcome evaluations of keloid and hypertrophic scar treatment with triamcinolone injection in mekong delta, vietnam - a cross-sectional study. |
2023-12-01 |
2023-12-07 |
Not clear |
| Lam Van Nguyen, Huy Quang Ly, Hau Thi Vo, Thao Thanh Pham, Nam Ky Nguyen, Thi Van Vo, Trung Quoc Phan, Phuong Thi Ngoc Tran, Hung Huynh Vinh Ly, Ha Thi Thao Ma. Clinical Features and the Outcome Evaluations of Keloid and Hypertrophic Scar Treatment with Triamcinolone Injection in Mekong Delta, Vietnam - A Cross-Sectional Study. Clinical, cosmetic and investigational dermatology. vol 16. 2023-12-01. PMID:38021426. |
clinical features and the outcome evaluations of keloid and hypertrophic scar treatment with triamcinolone injection in mekong delta, vietnam - a cross-sectional study. |
2023-11-29 |
2023-12-07 |
Not clear |
| Yujie Hua, Kai Wang, Yingying Huo, Yaping Zhuang, Yuhui Wang, Wenzhuo Fang, Yuyan Sun, Guangdong Zhou, Qiang Fu, Wenguo Cui, Kaile Zhan. Four-dimensional hydrogel dressing adaptable to the urethral microenvironment for scarless urethral reconstruction. Nature communications. vol 14. issue 1. 2023-11-25. PMID:37993447. |
as a result, physiological urethral recovery is successfully mimicked by means of an early-vascularized microenvironment to promote wound healing by activating the vascular endothelial growth factor (vegf) signaling pathway, as well as a later-antifibrogenic microenvironment to prevent hypertrophic scar formation by timing transforming growth factor-β (tgfβ) signaling pathway inhibition. |
2023-11-25 |
2023-11-28 |
rabbit |
| Alejandro Joglar, Juquan Song, George Golovko, Jayson Jay, Steven Wolf, Amina El Ayad. Comparing the Effectiveness of Glucocorticoids in Preventing Hypertrophic Scar Diagnosis in Burn Patients. Medicina (Kaunas, Lithuania). vol 59. issue 11. 2023-11-25. PMID:38004018. |
comparing the effectiveness of glucocorticoids in preventing hypertrophic scar diagnosis in burn patients. |
2023-11-25 |
2023-11-28 |
Not clear |
| Qiannan Li, Chunming Lyu, Daqin Chen, Wanling Cai, Fang Kou, Qiang Li, Hai Wei, Huimin Zhan. Gallic Acid Treats Hypertrophic Scar in Rabbit Ears via the TGF-β/Smad and TRPC3 Signaling Pathways. Pharmaceuticals (Basel, Switzerland). vol 16. issue 11. 2023-11-25. PMID:38004381. |
gallic acid treats hypertrophic scar in rabbit ears via the tgf-β/smad and trpc3 signaling pathways. |
2023-11-25 |
2023-11-28 |
rabbit |
| Fang Ma, Honglin Liu, Tongtong Xia, Zhenghao Zhang, Shengchao Ma, Yinju Hao, Jiangyong Shen, Yideng Jiang, Nan L. HSFAS mediates fibroblast proliferation, migration, trans-differentiation and apoptosis in hypertrophic scars via interacting with ADAMTS8. Acta biochimica et biophysica Sinica. 2023-11-25. PMID:38006215. |
hypertrophic scar (hs) is one of the most common sequelae of patients, especially after burns and trauma. |
2023-11-25 |
2023-11-28 |
human |