| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Vezzani, M Conti, A De Luigi, T Ravizza, D Moneta, F Marchesi, M G De Simon. Interleukin-1beta immunoreactivity and microglia are enhanced in the rat hippocampus by focal kainate application: functional evidence for enhancement of electrographic seizures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 12. 1999-06-28. PMID:10366638. |
next, we studied whether eeg seizures per se induced il-1beta and microglia changes in the hippocampus using bicuculline as a nonexcitotoxic convulsant agent. |
1999-06-28 |
2023-08-12 |
human |
| K Nakaso, M Kitayama, K Kimura, T Yanagawa, E Ohama, K Nakashima, T Ishii, K Yamad. Induction of heme oxygenase-1 in the rat brain by kainic acid-mediated excitotoxicity: the dissociation of mRNA and protein expression in hippocampus. Biochemical and biophysical research communications. vol 259. issue 1. 1999-06-25. PMID:10334921. |
immunohistochemical analysis showed that the positive cells in the cerebral cortex and hippocampus were mainly astrocytes and microglia, whereas neurons in the basal ganglia showed intense immunoreactivity. |
1999-06-25 |
2023-08-12 |
rat |
| Y Matsuoka, Y Kitamura, H Takahashi, I Tooyama, H Kimura, P J Gebicke-Haerter, Y Nomura, T Taniguch. Interferon-gamma plus lipopolysaccharide induction of delayed neuronal apoptosis in rat hippocampus. Neurochemistry international. vol 34. issue 2. 1999-06-10. PMID:10213066. |
although microglia appeared morphologically ramified in the normal and vehicle-injected hippocampus, microinjection of ifn-gamma/lps immediately induced the ameboid type. |
1999-06-10 |
2023-08-12 |
rat |
| M P Flavin, L T H. Propentofylline protects neurons in culture from death triggered by macrophage or microglial secretory products. Journal of neuroscience research. vol 56. issue 1. 1999-06-07. PMID:10213475. |
we recently demonstrated that conditioned medium (cm) from peritoneal macrophages or activated microglia triggers a predominantly apoptotic death in hippocampal neurons in culture. |
1999-06-07 |
2023-08-12 |
Not clear |
| B Conti, L C Park, N Y Calingasan, Y Kim, H Kim, Y Bae, G E Gibson, T H Jo. Cultures of astrocytes and microglia express interleukin 18. Brain research. Molecular brain research. vol 67. issue 1. 1999-05-21. PMID:10101231. |
the presence of il-18 and its response to stimulation in the brain was tested with primary cultures of microglia, astrocytes and hippocampal neurons. |
1999-05-21 |
2023-08-12 |
Not clear |
| S A Bennett, J Chen, B A Pappas, D C Roberts, M Tenniswoo. Platelet activating factor receptor expression is associated with neuronal apoptosis in an in vivo model of excitotoxicity. Cell death and differentiation. vol 5. issue 10. 1999-05-06. PMID:10203694. |
while pafr mrna is normally exhibited by neurons and microglia in rat hippocampus, expression becomes restricted to apoptotic neurons and to glia involved in phagocytosing apoptotic debris following treatment with excitotoxin. |
1999-05-06 |
2023-08-12 |
rat |
| Y Kondo, M Asanuma, E Iwata, F Kondo, I Miyazaki, N Ogaw. Early treatment with cyclosporin A ameliorates the reduction of muscarinic acetylcholine receptors in gerbil hippocampus after transient forebrain ischemia. Neurochemical research. vol 24. issue 1. 1999-05-03. PMID:9973231. |
however, csa did not alter reactive changes of astrocytes and microglia in the ca1 area of the hippocampus, which had been suppressed by daily administration. |
1999-05-03 |
2023-08-12 |
Not clear |
| L Ren, B Lubrich, K Biber, P J Gebicke-Haerte. Differential expression of inflammatory mediators in rat microglia cultured from different brain regions. Brain research. Molecular brain research. vol 65. issue 2. 1999-04-07. PMID:10064890. |
in this study, microglia were isolated from 2-4 week-old mixed cns cultures that had been prepared from neonatal rat diencephalon, tegmentum, hippocampus, cerebellum and cerebral cortex, and were investigated 24 h later. |
1999-04-07 |
2023-08-12 |
rat |
| L Ren, B Lubrich, K Biber, P J Gebicke-Haerte. Differential expression of inflammatory mediators in rat microglia cultured from different brain regions. Brain research. Molecular brain research. vol 65. issue 2. 1999-04-07. PMID:10064890. |
the results clearly show, that three of these mrnas (tnf-alpha, cd4, fcgamma receptor ii) are differentially expressed in microglia with hippocampal microglia displaying the highest levels of these mrnas. |
1999-04-07 |
2023-08-12 |
rat |
| J M Long, A N Kalehua, N J Muth, M E Calhoun, M Jucker, J M Hengemihle, D K Ingram, P R Mouto. Stereological analysis of astrocyte and microglia in aging mouse hippocampus. Neurobiology of aging. vol 19. issue 5. 1999-03-11. PMID:9880052. |
stereological analysis of astrocyte and microglia in aging mouse hippocampus. |
1999-03-11 |
2023-08-12 |
mouse |
| J M Long, A N Kalehua, N J Muth, M E Calhoun, M Jucker, J M Hengemihle, D K Ingram, P R Mouto. Stereological analysis of astrocyte and microglia in aging mouse hippocampus. Neurobiology of aging. vol 19. issue 5. 1999-03-11. PMID:9880052. |
to test the hypothesis that the number of microglia and astrocytes increase in the hippocampus during normal aging, unbiased stereological techniques were used to estimate total cell number in hippocampal subregions (ca1, dentate gyrus and hilus) of male c57bl/6j mice of different ages: 4-5 months, 13-14 months and 27-28 months. |
1999-03-11 |
2023-08-12 |
mouse |
| J M Long, A N Kalehua, N J Muth, M E Calhoun, M Jucker, J M Hengemihle, D K Ingram, P R Mouto. Stereological analysis of astrocyte and microglia in aging mouse hippocampus. Neurobiology of aging. vol 19. issue 5. 1999-03-11. PMID:9880052. |
no statistically significant age differences were found in the numbers of microglia or astrocytes in the hippocampal regions sampled. |
1999-03-11 |
2023-08-12 |
mouse |
| J M Long, A N Kalehua, N J Muth, M E Calhoun, M Jucker, J M Hengemihle, D K Ingram, P R Mouto. Stereological analysis of astrocyte and microglia in aging mouse hippocampus. Neurobiology of aging. vol 19. issue 5. 1999-03-11. PMID:9880052. |
these findings suggest that age-related increases in the total numbers of hippocampal microglia and astrocytes is not causal for observed age-related increases in cytokine response. |
1999-03-11 |
2023-08-12 |
mouse |
| J M Long, A N Kalehua, N J Muth, J M Hengemihle, M Jucker, M E Calhoun, D K Ingram, P R Mouto. Stereological estimation of total microglia number in mouse hippocampus. Journal of neuroscience methods. vol 84. issue 1-2. 1999-01-26. PMID:9821640. |
stereological estimation of total microglia number in mouse hippocampus. |
1999-01-26 |
2023-08-12 |
mouse |
| J M Long, A N Kalehua, N J Muth, J M Hengemihle, M Jucker, M E Calhoun, D K Ingram, P R Mouto. Stereological estimation of total microglia number in mouse hippocampus. Journal of neuroscience methods. vol 84. issue 1-2. 1999-01-26. PMID:9821640. |
in the present study, immunocytochemistry was combined with unbiased stereology to estimate the mean total number of microglia in dentate gyrus and ca1 regions of the mouse hippocampus. |
1999-01-26 |
2023-08-12 |
mouse |
| J M Long, A N Kalehua, N J Muth, J M Hengemihle, M Jucker, M E Calhoun, D K Ingram, P R Mouto. Stereological estimation of total microglia number in mouse hippocampus. Journal of neuroscience methods. vol 84. issue 1-2. 1999-01-26. PMID:9821640. |
the time required to determine total microglia number in both hippocampal sub-regions was approximately 6 h per mouse from stained sections. |
1999-01-26 |
2023-08-12 |
mouse |
| I Dalmau, B Finsen, J Zimmer, B González, B Castellan. Development of microglia in the postnatal rat hippocampus. Hippocampus. vol 8. issue 5. 1999-01-22. PMID:9825958. |
development of microglia in the postnatal rat hippocampus. |
1999-01-22 |
2023-08-12 |
rat |
| I Dalmau, B Finsen, J Zimmer, B González, B Castellan. Development of microglia in the postnatal rat hippocampus. Hippocampus. vol 8. issue 5. 1999-01-22. PMID:9825958. |
during the prenatal development of the hippocampus, microglial cell precursors progressively occur in all subfields in accordance with known ontogenetic gradients of the region (dalmau et al., j. comp. |
1999-01-22 |
2023-08-12 |
rat |
| I Dalmau, B Finsen, J Zimmer, B González, B Castellan. Development of microglia in the postnatal rat hippocampus. Hippocampus. vol 8. issue 5. 1999-01-22. PMID:9825958. |
the present study follows the regional distribution of these microglial cell precursors and their morphological differentiation in the rat hippocampus from birth to postnatal (p) day 18. |
1999-01-22 |
2023-08-12 |
rat |
| I Dalmau, B Finsen, J Zimmer, B González, B Castellan. Development of microglia in the postnatal rat hippocampus. Hippocampus. vol 8. issue 5. 1999-01-22. PMID:9825958. |
the appearance of microglia in the hippocampal subregions and differentiation of cell precursors into adult microglia occur earlier at temporal levels than at septal levels. |
1999-01-22 |
2023-08-12 |
rat |