Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Cyril Chéret, Annie Gervais, Aurélia Lelli, Catherine Colin, Lahouari Amar, Philippe Ravassard, Jacques Mallet, Ana Cumano, Karl-Heinz Krause, Michel Malla. Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 46. 2009-01-26. PMID:19005069. |
comparisons of microglia purified from wt, nox2-ko, or nox1-ko mice indicate that both nox1 and nox2 are required to optimize microglial production of nitric oxide. |
2009-01-26 |
2023-08-12 |
mouse |
Jaegyu Hwang, Long Tai Zheng, Jiyeon Ock, Maan Gee Lee, Sang-Hyun Kim, Ho-Won Lee, Won-Ha Lee, Hae-Chul Park, Kyoungho Su. Inhibition of glial inflammatory activation and neurotoxicity by tricyclic antidepressants. Neuropharmacology. vol 55. issue 5. 2009-01-15. PMID:18639562. |
the results showed that clomipramine and imipramine significantly decreased the production of nitric oxide or tumor necrosis factor-alpha (tnf-alpha) in microglia and astrocyte cultures. |
2009-01-15 |
2023-08-12 |
Not clear |
Ryan J Horvath, Nancy Nutile-McMenemy, Matthew S Alkaitis, Joyce A Dele. Differential migration, LPS-induced cytokine, chemokine, and NO expression in immortalized BV-2 and HAPI cell lines and primary microglial cultures. Journal of neurochemistry. vol 107. issue 2. 2008-12-24. PMID:18717813. |
bv-2 and hapi cells responded similarly to primary microglia in experiments assessing migration, ionized calcium binding adaptor molecule 1 expression, and nitric oxide release. |
2008-12-24 |
2023-08-12 |
rat |
Long Tai Zheng, Jaegyu Hwang, Jiyeon Ock, Maan Gee Lee, Won-Ha Lee, Kyoungho Su. The antipsychotic spiperone attenuates inflammatory response in cultured microglia via the reduction of proinflammatory cytokine expression and nitric oxide production. Journal of neurochemistry. vol 107. issue 5. 2008-12-24. PMID:18786164. |
the antipsychotic spiperone attenuates inflammatory response in cultured microglia via the reduction of proinflammatory cytokine expression and nitric oxide production. |
2008-12-24 |
2023-08-12 |
Not clear |
Long Tai Zheng, Jaegyu Hwang, Jiyeon Ock, Maan Gee Lee, Won-Ha Lee, Kyoungho Su. The antipsychotic spiperone attenuates inflammatory response in cultured microglia via the reduction of proinflammatory cytokine expression and nitric oxide production. Journal of neurochemistry. vol 107. issue 5. 2008-12-24. PMID:18786164. |
the results showed that spiperone significantly decreased the production of nitric oxide in lipopolysaccharide-stimulated bv-2 microglia cells, primary microglia and primary astrocyte cultures. |
2008-12-24 |
2023-08-12 |
Not clear |
Long Tai Zheng, Jaegyu Hwang, Jiyeon Ock, Maan Gee Lee, Won-Ha Lee, Kyoungho Su. The antipsychotic spiperone attenuates inflammatory response in cultured microglia via the reduction of proinflammatory cytokine expression and nitric oxide production. Journal of neurochemistry. vol 107. issue 5. 2008-12-24. PMID:18786164. |
spiperone also significantly inhibited nitric oxide production in adenosine 5'-triphosphate (atp)-stimulated primary microglia cultures. |
2008-12-24 |
2023-08-12 |
Not clear |
Anja Hoffmann, Fred Hofmann, Ingo Just, Seija Lehnardt, Uwe-Karsten Hanisch, Wolfgang Brück, Helmut Kettenmann, Gudrun Ahnert-Hilger, Markus Höltj. Inhibition of Rho-dependent pathways by Clostridium botulinum C3 protein induces a proinflammatory profile in microglia. Glia. vol 56. issue 11. 2008-12-18. PMID:18442097. |
nanomolar concentrations of c3bot transformed microglia towards an activated phenotype and triggered the release of nitric oxide and several proinflammatory cyto- and chemokines. |
2008-12-18 |
2023-08-12 |
mouse |
Jaegyu Hwang, Long Tai Zheng, Jiyeon Ock, Maan Gee Lee, Kyoungho Su. Anti-inflammatory effects of m-chlorophenylpiperazine in brain glia cells. International immunopharmacology. vol 8. issue 12. 2008-12-03. PMID:18771755. |
our results showed that m-cpp significantly decreased the production of nitric oxide, tumor necrosis factor-alpha (tnf-alpha), and interleukin-1beta (il-1beta) in microglia and astrocyte cultures. |
2008-12-03 |
2023-08-12 |
Not clear |
Han-Qing Chen, Xi-Jin Wang, Zheng-Yu Jin, Xue-Ming Xu, Jian-Wei Zhao, Zheng-Jun Xi. Protective effect of isoflavones from Trifolium pratense on dopaminergic neurons. Neuroscience research. vol 62. issue 2. 2008-12-02. PMID:18675857. |
moreover, they also significantly inhibited lps-induced activation of microglia and production of tumor necrosis factor-alpha, nitric oxide and superoxide in mesencephalic neuron-glia cultures and microglia-enriched cultures. |
2008-12-02 |
2023-08-12 |
rat |
Guo Hua Jin, Sang Keun Ha, Hye Min Park, Bomi Kang, Sun Yeou Kim, Hee-Do Kim, Jae-Ha Ryu, Raok Jeo. Synthesis of azaisoflavones and their inhibitory activities of NO production in activated microglia. Bioorganic & medicinal chemistry letters. vol 18. issue 14. 2008-11-17. PMID:18556197. |
a series of azaisoflavones were synthesized and their biological activities were evaluated for nitric oxide (no) production and inducible no synthase (inos) expression in bv-2 microglia cell lines. |
2008-11-17 |
2023-08-12 |
Not clear |
X L Meng, G L Chen, J Y Yang, S Wang, C F Wu, J M Wan. Inhibitory effect of a novel resveratrol derivative on nitric oxide production in lipopolysaccharide-activated microglia. Die Pharmazie. vol 63. issue 9. 2008-10-23. PMID:18819521. |
inhibitory effect of a novel resveratrol derivative on nitric oxide production in lipopolysaccharide-activated microglia. |
2008-10-23 |
2023-08-12 |
rat |
Jiraporn Tocharus, Sukumal Chongthammakun, Piyarat Govitrapon. Melatonin inhibits amphetamine-induced nitric oxide synthase mRNA overexpression in microglial cell lines. Neuroscience letters. vol 439. issue 2. 2008-10-14. PMID:18524487. |
furthermore, nitric oxide (no), produced in the central nervous system (cns) mediated by the activation of microglia, appears to play a critical role in stress-induced brain damage. |
2008-10-14 |
2023-08-12 |
rat |
Mohammad R Khazaei, Mehran Habibi-Rezaei, Fereshteh Karimzadeh, Ali Akbar Moosavi-Movahedi, Abdo Alfattah Sarrafnejhad, Farzaneh Sabouni, Mostafa Bakht. Microglial cell death induced by glycated bovine serum albumin: nitric oxide involvement. Journal of biochemistry. vol 144. issue 2. 2008-10-10. PMID:18463114. |
microglial cell death induced by glycated bovine serum albumin: nitric oxide involvement. |
2008-10-10 |
2023-08-12 |
cattle |
Avik Roy, Arundhati Jana, Kavitha Yatish, Matthew B Freidt, Yiu K Fung, Jeffrey A Martinson, Kalipada Paha. Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases. Free radical biology & medicine. vol 45. issue 5. 2008-10-03. PMID:18590811. |
reactive oxygen species up-regulate cd11b in microglia via nitric oxide: implications for neurodegenerative diseases. |
2008-10-03 |
2023-08-12 |
mouse |
Hyo Won Jung, Hye Young Son, Chau Van Minh, Young Ho Kim, Yong-Ki Par. Methanol extract of Ficus leaf inhibits the production of nitric oxide and proinflammatory cytokines in LPS-stimulated microglia via the MAPK pathway. Phytotherapy research : PTR. vol 22. issue 8. 2008-10-02. PMID:18546149. |
methanol extract of ficus leaf inhibits the production of nitric oxide and proinflammatory cytokines in lps-stimulated microglia via the mapk pathway. |
2008-10-02 |
2023-08-12 |
mouse |
Hyo Won Jung, Hye Young Son, Chau Van Minh, Young Ho Kim, Yong-Ki Par. Methanol extract of Ficus leaf inhibits the production of nitric oxide and proinflammatory cytokines in LPS-stimulated microglia via the MAPK pathway. Phytotherapy research : PTR. vol 22. issue 8. 2008-10-02. PMID:18546149. |
excessive production of inflammatory mediators, nitric oxide (no) and proinflammatory cytokines from activated microglia has been implicated in neurodegeneration in human brain diseases. |
2008-10-02 |
2023-08-12 |
mouse |
Ki Yong Lee, Seung Hyun Kim, Sang Hyun Sung, Young Choong Ki. Inhibitory constituents of lipopolysaccharide-induced nitric oxide production in BV2 microglia isolated from Amomum tsao-ko. Planta medica. vol 74. issue 8. 2008-09-17. PMID:18523923. |
inhibitory constituents of lipopolysaccharide-induced nitric oxide production in bv2 microglia isolated from amomum tsao-ko. |
2008-09-17 |
2023-08-12 |
Not clear |
Ki Yong Lee, Seung Hyun Kim, Sang Hyun Sung, Young Choong Ki. Inhibitory constituents of lipopolysaccharide-induced nitric oxide production in BV2 microglia isolated from Amomum tsao-ko. Planta medica. vol 74. issue 8. 2008-09-17. PMID:18523923. |
a methanolic extract of the fruits of amomum tsao-ko (zingiberaceae) significantly attenuated nitric oxide production in lipopolysaccharide-simulated bv2 microglia. |
2008-09-17 |
2023-08-12 |
Not clear |
Takahiro Kato, Yoshito Mizoguchi, Akira Monji, Hideki Horikawa, Satoshi O Suzuki, Yoshihiro Seki, Toru Iwaki, Sadayuki Hashioka, Shigenobu Kanb. Inhibitory effects of aripiprazole on interferon-gamma-induced microglial activation via intracellular Ca2+ regulation in vitro. Journal of neurochemistry. vol 106. issue 2. 2008-09-16. PMID:18429930. |
not quinpirole, dopamine d(2) full agonist, but aripiprazole significantly inhibited the generation of nitric oxide (no) and tumor necrosis factor (tnf)-alpha from ifn-gamma-activated microglia and suppressed the ifn-gamma-induced elevation of intracellular ca(2+) concentrations ([ca(2+)](i)) in murine microglial cells. |
2008-09-16 |
2023-08-12 |
Not clear |
Xue-Lian Meng, Jing-Yu Yang, Guo-Liang Chen, Li-Hui Wang, Li-Jia Zhang, Shu Wang, Jie Li, Chun-Fu W. Effects of resveratrol and its derivatives on lipopolysaccharide-induced microglial activation and their structure-activity relationships. Chemico-biological interactions. vol 174. issue 1. 2008-09-15. PMID:18513711. |
the inhibitory effects of 21 resveratrol derivatives on lipopolysaccharide (lps)-induced nitric oxide (no) production in microglia and their structure-activity relationships were studied. |
2008-09-15 |
2023-08-12 |
Not clear |