| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hong-Hua Li, Xi-Fei Wang, Bing Wang, Fei-Yong Ji. Vitamin D3 improves iminodipropionitrile-induced tic-like behavior in rats through regulation of GDNF/c-Ret signaling activity. European child & adolescent psychiatry. 2024-02-24. PMID:38396228. |
all groups were tested for behavior, serum and striatal 25(oh)d and dopamine (da), mrna expressions of vitamin d receptor (vdr), glial cell line-derived neurotrophic factor (gdnf), protooncogene tyrosine-protein kinase receptor ret (c-ret), and da d1 (drd1) and d2 (drd2) receptor genes in the striatum. |
2024-02-24 |
2024-02-26 |
rat |
| Conor Giles Doran, Fionnuala Wilson, Susan R Goulding, Martina Mazzocchi, Louise M Collins, Aideen M Sullivan, Gerard W O'Keeff. Bioinformatics and Immunohistochemical Analyses Support Preserved Expression of Glial Cell Line-Derived Neurotrophic Factor Receptor RET in Parkinson's. Movement disorders : official journal of the Movement Disorder Society. vol 38. issue 6. 2023-07-21. PMID:37475614. |
bioinformatics and immunohistochemical analyses support preserved expression of glial cell line-derived neurotrophic factor receptor ret in parkinson's. |
2023-07-21 |
2023-08-14 |
Not clear |
| Daniel R Garton, Giorgio Turconi, Vilma Iivanainen, Jaan-Olle Andresso. Opposing Spatially Segregated Function of Endogenous GDNF-RET Signaling in Cocaine Addiction. Biomolecules. vol 13. issue 5. 2023-05-27. PMID:37238631. |
as a potent neurotrophic factor modulating the function of dopamine neurons, glial cell line-derived neurotrophic factor (gdnf) acting through its receptor ret on dopamine neurons may provide a novel therapeutic avenue towards psychostimulant addiction. |
2023-05-27 |
2023-08-14 |
Not clear |
| Ziyi Zhao, Xuantong Dai, Gengru Jiang, Fujun Li. ASH2L Controls Ureteric Bud Morphogenesis via Regulation of RET/GFRA1 Signaling Activity in a Mouse Model. Journal of the American Society of Nephrology : JASN. 2023-02-09. PMID:36758123. |
signaling involving glial cell line-derived neurotrophic factor and its receptor ret and coreceptor gfra1 appears to be particularly important in ureteric bud development. |
2023-02-09 |
2023-08-14 |
mouse |
| Praseeda Mol, Rex Devasahayam Arokia Balaya, Shobha Dagamajalu, Sreeranjini Babu, Pavithra Chandrasekaran, Reshma Raghavan, Sneha Suresh, Namitha Ravishankara, Anu Hemalatha Raju, Bipin Nair, Prashant Kumar Modi, Anita Mahadevan, Thottethodi Subrahmanya Keshava Prasad, Rajesh Raj. A network map of GDNF/RET signaling pathway in physiological and pathological conditions. Journal of cell communication and signaling. 2023-01-30. PMID:36715855. |
glial cell line-derived neurotrophic factor (gdnf) signals through a multi-component receptor system predominantly consisting of glycosyl-phosphatidylinositol-anchored gdnf family receptor alpha-1 (gfrα1) and the rearranged during transfection (ret) receptor tyrosine kinase. |
2023-01-30 |
2023-08-14 |
Not clear |
| Masahide Takahash. RET receptor signaling: Function in development, metabolic disease, and cancer. Proceedings of the Japan Academy. Series B, Physical and biological sciences. vol 98. issue 3. 2022-03-14. PMID:35283407. |
ret receptors are physiologically activated by glial cell line-derived neurotrophic factor (gdnf) family ligands that bind to the coreceptor gdnf family receptor α (gfrα). |
2022-03-14 |
2023-08-13 |
human |
| Kristijan Pazur, Ioannis Giannios, Mathias Lesche, Eva Rodriguez-Aznar, Anthony Gavala. Hoxb1 Regulates Distinct Signaling Pathways in Neuromesodermal and Hindbrain Progenitors to Promote Cell Survival and Specification. Stem cells (Dayton, Ohio). 2022-03-08. PMID:35257173. |
finally, hoxb1 synergizes with exogenous glial cell line-derived neurotrophic factor (gdnf) to strengthen ret expression and further promote the generation of fbm-like progenitors. |
2022-03-08 |
2023-08-13 |
mouse |
| James A Conway, Edgar R Krame. Is activation of GDNF/RET signaling the answer for successful treatment of Parkinson's disease? A discussion of data from the culture dish to the clinic. Neural regeneration research. vol 17. issue 7. 2021-12-17. PMID:34916419. |
the neurotrophic signaling of glial cell line-derived neurotrophic factor (gdnf) with its canonical receptor, the receptor tyrosine kinase ret, coupled together with the gdnf family receptor alpha 1 is important for dopaminergic neuron survival and physiology in cell culture experiments and animal models. |
2021-12-17 |
2023-08-13 |
Not clear |
| Susan R Goulding, Jayanth Anantha, Louise M Collins, Aideen M Sullivan, Gerard W O'Keeff. Growth differentiation factor 5: a neurotrophic factor with neuroprotective potential in Parkinson's disease. Neural regeneration research. vol 17. issue 1. 2021-10-22. PMID:34100424. |
this failure is thought to be at least partly due to the downregulation by α-synuclein of ret, the common co-receptor of glial cell line-derived neurorophic factor and neurturin. |
2021-10-22 |
2023-08-13 |
rat |
| Emma Connolly, David J Morgan, Miriam Franklin, Angela Simpson, Rajesh Shah, Oliver J Brand, Christopher P Jagger, Joshua Casulli, Karishma Mohamed, Aleksander M Grabiec, Tracy Hussel. Neurturin regulates the lung-resident macrophage inflammatory response to viral infection. Life science alliance. vol 3. issue 12. 2021-07-13. PMID:33020210. |
this circuit involves type 1 interferon-induced up-regulation of ret that when combined with the glial cell line-derived neurotrophic factor (gdnf) receptor α2 (gfrα2) allows binding to epithelial-derived nrtn. |
2021-07-13 |
2023-08-13 |
human |
| Arun Kumar Mahato, Yulia A Sidorov. Glial cell line-derived neurotrophic factors (GFLs) and small molecules targeting RET receptor for the treatment of pain and Parkinson's disease. Cell and tissue research. vol 382. issue 1. 2021-06-23. PMID:32556722. |
glial cell line-derived neurotrophic factors (gfls) and small molecules targeting ret receptor for the treatment of pain and parkinson's disease. |
2021-06-23 |
2023-08-13 |
Not clear |
| Arun Kumar Mahato, Yulia A Sidorov. Glial cell line-derived neurotrophic factors (GFLs) and small molecules targeting RET receptor for the treatment of pain and Parkinson's disease. Cell and tissue research. vol 382. issue 1. 2021-06-23. PMID:32556722. |
rearranged during transfection (ret), in complex with glial cell line-derived (gdnf) family receptor alpha (gfrα), is the canonical signaling receptor for gdnf family ligands (gfls) expressed in both central and peripheral parts of the nervous system and also in non-neuronal tissues. |
2021-06-23 |
2023-08-13 |
Not clear |
| Kumi Kawai, Masahide Takahash. Intracellular RET signaling pathways activated by GDNF. Cell and tissue research. vol 382. issue 1. 2021-06-23. PMID:32816064. |
physiologically, ret is activated by glial cell line-derived neurotrophic factor (gdnf) ligands that bind to coreceptor gdnf family receptor alphas (gfrαs), leading to ret dimerization. |
2021-06-23 |
2023-08-13 |
human |
| James A Conway, Selvi Ince, Stephanie Black, Edgar R Krame. GDNF/RET signaling in dopamine neurons in vivo. Cell and tissue research. vol 382. issue 1. 2021-06-23. PMID:32870383. |
the glial cell line-derived neurotrophic factor (gdnf) and its canonical receptor ret can signal both in tandem and separately to exert many vital functions in the midbrain dopamine system. |
2021-06-23 |
2023-08-13 |
Not clear |
| Juho-Matti Renko, Merja H Voutilainen, Tanel Visnapuu, Yulia A Sidorova, Mart Saarma, Raimo K Tuomine. GDNF Receptor Agonist Alleviates Motor Imbalance in Unilateral 6-Hydroxydopamine Model of Parkinson's Disease. Frontiers in neurology and neuroscience research. vol 1. 2021-03-26. PMID:33479704. |
ret is the signalling receptor for a known survival factor for dopamine neurons called glial cell line-derived neurotrophic factor (gdnf). |
2021-03-26 |
2023-08-13 |
rat |
| Hyo Jeong Lee, Pyeonghwa Jeong, Yeongyu Moon, Jungil Choi, Jeong Doo Heo, Yong-Chul Kim, Sun-Young Ha. Characterization of LDD-2633 as a Novel RET Kinase Inhibitor with Anti-Tumor Effects in Thyroid Cancer. Pharmaceuticals (Basel, Switzerland). vol 14. issue 1. 2021-02-18. PMID:33419162. |
rearranged during transfection (ret), a receptor tyrosine kinase, is activated by glial cell line-derived neurotrophic factor family ligands. |
2021-02-18 |
2023-08-13 |
Not clear |
| Liliane Tenenbaum, Marie Humbert-Claud. Glial Cell Line-Derived Neurotrophic Factor Gene Delivery in Parkinson's Disease: A Delicate Balance between Neuroprotection, Trophic Effects, and Unwanted Compensatory Mechanisms. Frontiers in neuroanatomy. vol 11. 2020-10-01. PMID:28442998. |
glial cell line-derived neurotrophic factor (gdnf) and neurturin (nrtn) bind to a receptor complex consisting of a member of the gdnf family receptor (gfr)-α and the ret tyrosine kinase. |
2020-10-01 |
2023-08-13 |
human |
| Wenxian Li, Di Wei, Jiaxing Lin, Jianye Liang, Xiaomei Xie, Kangping Song, Li'an Huan. Dl-3-n-Butylphthalide Reduces Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion Through GDNF/GFRα1/Ret Signaling Preventing Hippocampal Neuron Apoptosis. Frontiers in cellular neuroscience. vol 13. 2020-09-29. PMID:31456664. |
glial cell line-derived neurotrophic factor (gdnf)/gdnf family receptor alpha-1 (gfrα1)/receptor tyrosine kinase (ret) signaling is altered in the hippocampus of cch rats; however, nbp treatment improved cognitive function, protected against hippocampal neuron apoptosis |
2020-09-29 |
2023-08-13 |
rat |
| Takashi Kohno, Junya Tabata, Takashi Nakaok. REToma: a cancer subtype with a shared driver oncogene. Carcinogenesis. vol 41. issue 2. 2020-08-31. PMID:31711124. |
ret (rearranged during transfection), which encodes a receptor tyrosine kinase for members of the glial cell line-derived neurotrophic factor, plays a role as driver oncogene in a variety of human cancers. |
2020-08-31 |
2023-08-13 |
human |
| Sean Jmaeff, Yulia Sidorova, Hayley Lippiatt, Pablo F Barcelona, Hinyu Nedev, Lucia M Saragovi, Mark A Hancock, Mart Saarma, H Uri Saragov. Small-Molecule Ligands that Bind the RET Receptor Activate Neuroprotective Signals Independent of but Modulated by Coreceptor GFR Molecular pharmacology. vol 98. issue 1. 2020-07-30. PMID:32362584. |
small-molecule ligands that bind the ret receptor activate neuroprotective signals independent of but modulated by coreceptor gfr glial cell line-derived neurotrophic factor (gdnf) binds the gfr |
2020-07-30 |
2023-08-13 |
Not clear |