| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| James H Fox, James E Hassell, Philip H Siebler, Mathew R Arnold, Andrew K Lamb, David G Smith, Heidi E W Day, Tessa M Smith, Emma M Simmerman, Alexander A Outzen, Kaley S Holmes, Christopher J Brazell, Christopher A Lowr. Preimmunization with a heat-killed preparation of Mycobacterium vaccae enhances fear extinction in the fear-potentiated startle paradigm. Brain, behavior, and immunity. vol 66. 2018-06-06. PMID:28888667. |
rats were euthanized on day 11 and brain tissue was sectioned for analysis of mrna expression for genes important in control of brain serotonergic signaling, including tph2, htr1a, slc6a4, and slc22a3, throughout the brainstem dorsal and median raphe nuclei. |
2018-06-06 |
2023-08-13 |
mouse |
| Ronald G Garcia, Richard L Lin, Jeungchan Lee, Jieun Kim, Riccardo Barbieri, Roberta Sclocco, Ajay D Wasan, Robert R Edwards, Bruce R Rosen, Nouchine Hadjikhani, Vitaly Napado. Modulation of brainstem activity and connectivity by respiratory-gated auricular vagal afferent nerve stimulation in migraine patients. Pain. vol 158. issue 8. 2018-05-01. PMID:28541256. |
regulation of activity and connectivity of brainstem and cortical regions involved in serotonergic and noradrenergic regulation and pain modulation may constitute an underlying mechanism supporting beneficial clinical outcomes for eravans applied for episodic migraine. |
2018-05-01 |
2023-08-13 |
Not clear |
| Marco A Vindas, Angelico Madaro, Thomas W K Fraser, Erik Höglund, Rolf E Olsen, Tore S Kristiansen, Øyvind Øverl. Uncontrollable chronic stress reduces growth disparities in farmed Atlantic salmon. Physiology & behavior. vol 179. 2018-05-01. PMID:28668622. |
furthermore, we found brain serotonergic signaling and corticotropic releasing factor binding protein expression were positively associated with brain stem serotonergic activity, which is consistent with fish showing a stress reactivity neurophysiological profile. |
2018-05-01 |
2023-08-13 |
Not clear |
| Oi Wan Wan, Eunju Shin, Bengt Mattsson, Dorian Caudal, Per Svenningsson, Anders Björklun. α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter. Scientific reports. vol 6. 2018-04-02. PMID:27211987. |
we studied the impact of α-synuclein overexpression in brainstem serotonin neurons using a novel vector construct where the expression of human wildtype α-synuclein is driven by the tryptophan hydroxylase promoter, allowing expression of α-synuclein at elevated levels, and with high selectivity, in serotonergic neurons. |
2018-04-02 |
2023-08-13 |
human |
| Yongzhi Xia, Dan Chen, Haijian Xia, Zhengbu Liao, Wenyuan Tang, Yi Ya. Serotonergic projections to lumbar levels and its plasticity following spinal cord injury. Neuroscience letters. vol 649. 2018-03-08. PMID:28396282. |
the descending serotonergic pathway, which originates in various populations of brainstem neurons, plays an important role in generating the rhythmic motor pattern associated with locomotor movement. |
2018-03-08 |
2023-08-13 |
mouse |
| Jabir Mohamed, Brian W Scot. Impaired Cardiorespiratory Function during Focal Limbic Seizures: A Role for Serotonergic Brainstem Nuclei. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 34. 2018-01-12. PMID:27559160. |
impaired cardiorespiratory function during focal limbic seizures: a role for serotonergic brainstem nuclei. |
2018-01-12 |
2023-08-13 |
Not clear |
| Satoshi Ansai, Hiroshi Hosokawa, Shingo Maegawa, Kiyoshi Naruse, Youhei Washio, Kenji Sato, Masato Kinoshit. Deficiency of Serotonin in Raphe Neurons and Altered Behavioral Responses in Tryptophan Hydroxylase 2-Knockout Medaka (Oryzias latipes). Zebrafish. vol 14. issue 6. 2018-01-05. PMID:28933662. |
teleost fish species have serotonergic neurons in the raphe nuclei of the brainstem; however, the role of 5-ht in the raphe neurons in teleost fish remains largely unknown. |
2018-01-05 |
2023-08-13 |
Not clear |
| Scott A Givan, Kevin J Cumming. Intermittent severe hypoxia induces plasticity within serotonergic and catecholaminergic neurons in the neonatal rat ventrolateral medulla. Journal of applied physiology (Bethesda, Md. : 1985). vol 120. issue 11. 2017-12-14. PMID:26968026. |
we hypothesized that 1) catecholaminergic neurons in the neonatal vlm are activated following ish, 2) this activation is compromised following an acute loss of brain stem 5-ht, and 3) ish induces cellular and/or transcriptomic plasticity within catecholaminergic and serotonergic neurons that are within or project to the vlm, respectively. |
2017-12-14 |
2023-08-13 |
rat |
| Yoshiyuki Numasawa, Takaaki Hattori, Sumio Ishiai, Zen Kobayashi, Tomoyuki Kamata, Minoru Kotera, Satoru Ishibashi, Nobuo Sanjo, Hidehiro Mizusawa, Takanori Yokot. Depressive disorder may be associated with raphe nuclei lesions in patients with brainstem infarction. Journal of affective disorders. vol 213. 2017-11-27. PMID:28278447. |
the ascending serotonergic system originates from the raphe nuclei in the brainstem. |
2017-11-27 |
2023-08-13 |
Not clear |
| P M MacFarlane, C A Mayer, D G Litvi. Microglia modulate brainstem serotonergic expression following neonatal sustained hypoxia exposure: implications for sudden infant death syndrome. The Journal of physiology. vol 594. issue 11. 2017-08-07. PMID:26659585. |
microglia modulate brainstem serotonergic expression following neonatal sustained hypoxia exposure: implications for sudden infant death syndrome. |
2017-08-07 |
2023-08-13 |
Not clear |
| Daniela Brunert, Yusuke Tsuno, Markus Rothermel, Michael T Shipley, Matt Wachowia. Cell-Type-Specific Modulation of Sensory Responses in Olfactory Bulb Circuits by Serotonergic Projections from the Raphe Nuclei. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 25. 2017-07-10. PMID:27335411. |
serotonergic neurons in the brainstem raphe nuclei densely innervate the olfactory bulb (ob), where they can modulate the initial representation and processing of olfactory information. |
2017-07-10 |
2023-08-13 |
mouse |
| Aline P Pansani, Diego B Colugnati, Carla A Scorza, Antonio-Carlos G de Almeida, Esper A Cavalheiro, Fulvio A Scorz. Furthering our understanding of SUDEP: the role of animal models. Expert review of neurotherapeutics. vol 16. issue 5. 2017-06-27. PMID:27029803. |
impairments on adenosinergic and serotonergic systems, brainstem spreading depolarization, seizure-activation of neural substrates related to cardiorespiratory control, altered autonomic control, and mutations on sodium and potassium channels are hypothesis suggested. |
2017-06-27 |
2023-08-13 |
Not clear |
| Ilya Ayzenberg, Ilias Nastos, Katrin Strassburger-Krogias, Mark Obermann, Ralf Gold, Christos Krogia. Hypoechogenicity of brainstem raphe nuclei is associated with increased attack frequency in episodic migraine. Cephalalgia : an international journal of headache. vol 36. issue 8. 2017-03-02. PMID:26566936. |
reduced echogenicity of the brainstem raphe nuclei (brn) was demonstrated in major depression, possibly indicating serotonergic dysfunction. |
2017-03-02 |
2023-08-13 |
Not clear |
| Melissa A Papesh, Laura M Hurle. Modulation of auditory brainstem responses by serotonin and specific serotonin receptors. Hearing research. vol 332. 2016-12-13. PMID:26688176. |
this is the first study to describe the effects of serotonin on abr responses across a wide range of stimulus frequencies and amplitudes, and it presents an important step in understanding how serotonergic modulation of auditory brainstem processing may contribute to modulation of auditory perception. |
2016-12-13 |
2023-08-13 |
mouse |
| Emily A Karanges, Linnet Ramos, Bruno Dampney, Anastasia S Suraev, Kong M Li, Iain S McGregor, Glenn E Hun. Contrasting regional Fos expression in adolescent and young adult rats following acute administration of the antidepressant paroxetine. Brain research bulletin. vol 121. 2016-12-13. PMID:26876759. |
these results indicate a different c-fos signature of acute paroxetine in adolescent rats, with greater activation in key mesolimbic and serotonergic regions, but a more subdued cortical, brainstem and hypothalamic response. |
2016-12-13 |
2023-08-13 |
rat |
| Jong-Hoon Kim, Young-Don Son, Jeong-Hee Kim, Eun-Jung Choi, Sang-Yoon Lee, Yo-Han Joo, Young-Bo Kim, Zang-Hee Ch. Self-transcendence trait and its relationship with in vivo serotonin transporter availability in brainstem raphe nuclei: An ultra-high resolution PET-MRI study. Brain research. vol 1629. 2016-09-22. PMID:26459992. |
we examined the relationship between self-transcendence and serotonin transporter (sert) availability in brainstem raphe nuclei, which are collections of five different serotonergic nuclei with rostro-caudal extension, using ultra-high resolution magnetic resonance imaging (mri) and positron emission tomography (pet) with (11)c-3-amino-4-(2-dimethylaminomethylphenylthio)benzonitrile ([(11)c]dasb) to elucidate potential roles of serotonergic neuronal activities in this personality trait. |
2016-09-22 |
2023-08-13 |
human |
| Melissa J Maguire, Cerian F Jackson, Anthony G Marson, Sarah J Nola. Treatments for the prevention of Sudden Unexpected Death in Epilepsy (SUDEP). The Cochrane database of systematic reviews. vol 7. 2016-09-21. PMID:27434597. |
preventative strategies for sudep include reducing the occurrence of gtcs by timely referral for presurgical evaluation in people with lesional epilepsy and advice on lifestyle measures; detecting cardiorespiratory distress through clinical observation and seizure, respiratory, and heart rate monitoring devices; preventing airway obstruction through nocturnal supervision and safety pillows; reducing central hypoventilation through physical stimulation and enhancing serotonergic mechanisms of respiratory regulation using selective serotonin reuptake inhibitors (ssris); reducing adenosine and endogenous opioid-induced brain and brainstem depression. |
2016-09-21 |
2023-08-13 |
Not clear |
| Qiong Zhan, Gordon F Buchanan, Joshua E Motelow, John Andrews, Petr Vitkovskiy, William C Chen, Florian Serout, Abhijeet Gummadavelli, Adam Kundishora, Moran Furman, Wei Li, Xiao Bo, George B Richerson, Hal Blumenfel. Impaired Serotonergic Brainstem Function during and after Seizures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 9. 2016-08-16. PMID:26937010. |
impaired serotonergic brainstem function during and after seizures. |
2016-08-16 |
2023-08-13 |
rat |
| Qiong Zhan, Gordon F Buchanan, Joshua E Motelow, John Andrews, Petr Vitkovskiy, William C Chen, Florian Serout, Abhijeet Gummadavelli, Adam Kundishora, Moran Furman, Wei Li, Xiao Bo, George B Richerson, Hal Blumenfel. Impaired Serotonergic Brainstem Function during and after Seizures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 9. 2016-08-16. PMID:26937010. |
lower brainstem serotonergic systems are postulated to play an important role in cardiorespiratory changes during and after seizures, whereas upper brainstem serotonergic and other systems regulate arousal. |
2016-08-16 |
2023-08-13 |
rat |
| Qiong Zhan, Gordon F Buchanan, Joshua E Motelow, John Andrews, Petr Vitkovskiy, William C Chen, Florian Serout, Abhijeet Gummadavelli, Adam Kundishora, Moran Furman, Wei Li, Xiao Bo, George B Richerson, Hal Blumenfel. Impaired Serotonergic Brainstem Function during and after Seizures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 9. 2016-08-16. PMID:26937010. |
however, direct demonstration of seizure-associated neuronal activity changes in brainstem serotonergic regions has been lacking. |
2016-08-16 |
2023-08-13 |
rat |