| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi-Wei Hu, Jian Liu, Zi-Han Qiu, Xiao-Ying Li, Juan Li, Li Chen, Tao Wang, Xin-Feng Wang, Zhong-Jie Feng, Wan-Ting Bai, Yuan Guo, Li Zhan. Effects of astrocytes in the dorsal hippocampus on anxiety-like and depressive-like behaviors in hemiparkinsonian rats. Behavioural brain research. 2025-03-27. PMID:40147794. |
the present results showed that unilateral lesions of the snc induced anxiety-like and depressive-like behaviors, decreased dopamine (da) levels in some related brain regions, but did not change the density of glial fibrillary acidic protein-positive as in the ca1, ca3 and dentate gyrus in rats. |
2025-03-27 |
2025-03-30 |
rat |
| Muhammad Hussain Ali, Zain Raza, Zohabia Rehman, Waseem Ashraf, Syed Muhammad Muneeb Anjum, Tanveer Ahmad, Faleh Alqahtani, Imran Imra. Probiotics and pregabalin combination prevented ictogenesis, neurobehavioral abnormalities and neurodegeneration in pentylenetetrazole kindling model of epilepsy. Brain research. 2025-03-26. PMID:40139417. |
furthermore, these commensal species and prg duo regulates inflammation and halted neuronal apoptosis in ca1 and ca3 subfields of the cornu-ammonis. |
2025-03-26 |
2025-03-30 |
mouse |
| Krisztina Kelemen, Máté Sárosi, Ágnes Csüdör, Károly Orbán-Kis, Hanga Kelemen, László Bába, Zsolt Gáll, Eszter Horváth, István Katona, Tibor Szilágy. Marked differences in the effects of levetiracetam and its analogue brivaracetam on microglial, astrocytic, and neuronal density in the rat model of kainic acid-induced temporal lobe epilepsy. Frontiers in pharmacology. vol 16. 2025-03-21. PMID:40115266. |
the brv-epi group displayed a significantly higher microglia density than sham and epi groups in the right ca1, ca3 and left ca1 regions, bilateral amygdalae, epn, pvt and left pc. |
2025-03-21 |
2025-03-23 |
rat |
| Forouzan Rafie, Sedigheh Amiresmaili, Mohammad Amin Rajizadeh, Mohammad Pourranjbar, Elham Jafari, Mohammad Khaksari, Sara Shirazpour, Omid Moradnejad, Amir Hossein Nekoue. Optimal Timing of Exercise for Enhanced Learning and Memory: Insights From CA1 and CA3 Regions in Traumatic Brain Injury Model in Male Rats. Brain and behavior. vol 15. issue 3. 2025-03-13. PMID:40079502. |
optimal timing of exercise for enhanced learning and memory: insights from ca1 and ca3 regions in traumatic brain injury model in male rats. |
2025-03-13 |
2025-03-16 |
rat |
| Dan Wei, Shiwen Tan, Shujuan Pang, Bingshu Liu, Qiong Zhang, Siqi Zhu, Guiyu Fu, Dianjun Sun, Wei We. Protective effects of anthocyanins on the nervous system injury caused by fluoride-induced endoplasmic reticulum stress in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2025-03-12. PMID:40073964. |
the results showed that fluoride exposure could decrease the learning and memory ability in rats, and led to histopathological and ultrastructural damage in the hippocampal ca1, ca3 and cortical regions. |
2025-03-12 |
2025-03-15 |
rat |
| Dan Wei, Shiwen Tan, Shujuan Pang, Bingshu Liu, Qiong Zhang, Siqi Zhu, Guiyu Fu, Dianjun Sun, Wei We. Protective effects of anthocyanins on the nervous system injury caused by fluoride-induced endoplasmic reticulum stress in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2025-03-12. PMID:40073964. |
fluoride exposure-induced os in vivo, which further activates ers, which was manifested by increased levels of ers-related proteins grp78, caspase 12, and caspase 3 in hippocampal ca1, ca3, and cortical regions, and eventually led to a significant increase in neuronal apoptosis rate. |
2025-03-12 |
2025-03-15 |
rat |
| Lisa Traunmüller, Erin E Duffy, Hanqing Liu, Stella Sanalidou, Elena G Assad, Senmiao Sun, Naeem S Pajarillo, Nancy Niu, Eric C Griffith, Michael E Greenber. Novel environment exposure drives temporally defined and region-specific chromatin accessibility and gene expression changes in the hippocampus. bioRxiv : the preprint server for biology. 2025-03-10. PMID:40060638. |
we employed single- nucleus multiomics (snrna- and atac-seq) and bulk rna-seq of the hippocampal dg, ca3, and ca1 regions to characterize the temporal evolution of cell-type-specific chromatin accessibility and gene expression changes that occur in 14 different cell types of the hippocampus upon exposure of mice to a novel environment. |
2025-03-10 |
2025-03-12 |
mouse |
| Lilit Darbinyan, Karen Simonyan, Lilia Hambardzumyan, Larisa Manukyan, Kristine Karapetyan, Margarita Danielya. Impact of L-thyroxine on hippocampal activity, morphology, and behavioral performance in thyroidectomized rats. Metabolic brain disease. vol 40. issue 3. 2025-03-10. PMID:40063269. |
results revealed significant changes in hippocampal electrophysiological responses in the l-thyroxine-treated group, including enhanced synaptic plasticity, increased excitatory activity, and more frequent, synchronized neuronal firing in the ca1 and ca3 regions. |
2025-03-10 |
2025-03-13 |
rat |
| Qu Yang, Qi Chen, Kai-Bing Zhang, Yu Liu, Jia-Cheng Zheng, Dong-Xia Hu, Jun Lu. Sinomenine alleviates neuroinflammation in chronic cerebral hypoperfusion by promoting M2 microglial polarization and inhibiting neuronal pyroptosis via exosomal miRNA-223-3p. Acta neuropathologica communications. vol 13. issue 1. 2025-03-06. PMID:40045356. |
histological analysis revealed that sino effectively reduced neuroinflammation and damage in the hippocampal ca1, ca3, and dg regions. |
2025-03-06 |
2025-03-08 |
rat |
| Ekaterina V Fedorova, Irina Yu Chernomorets, Dmitry A Fedorov, Vladimir I Arkhipo. Delayed treatment with TGF-β1 associated neuroprotection in trimethyltin-induced hippocampal neurodegeneration. Neuroscience letters. 2025-03-06. PMID:40049360. |
in the passive avoidance test, tgf-β1 ameliorated tmt-induced long-term memory impairment and promoted neuronal preservation in the ca1 region of the hippocampus, although no such effect was observed in the ca3 and ca4 regions. |
2025-03-06 |
2025-03-09 |
rat |
| Yandara A Martins, Camila A E F Cardinali, Andréa S Torrã. Age-related differences in long-term memory performance and astrocyte morphology in rat hippocampus. Neurobiology of aging. vol 150. 2025-03-05. PMID:40043468. |
ca1, ca2, ca3, and the dentate gyrus were collected for immunohistochemistry analysis and glial fibrillary acid protein (gfap) immunostaining. |
2025-03-05 |
2025-03-08 |
rat |
| Ryan K Shahidehpour, Peter T Nelson, Sukanya Srinivasan, Zhong Yu, Adam D Bachstette. Assessing Co-Localization of ITM2B With Alzheimer's Disease and Limbic-Predominant Age-Related TDP-43 Encephalopathy Neuropathologic Changes. Neuropathology : official journal of the Japanese Society of Neuropathology. 2025-03-05. PMID:40042444. |
we investigated the patterns and co-localizations of itm2b immunohistochemistry in subiculum, ca1, ca2, ca3 and dentate gyrus of the hippocampus from brains with alzheimer's disease neuropathologic changes (adnc), late-nc, and comorbid adnc+late-nc, as well as low-pathology controls (n = 4 per disease state). |
2025-03-05 |
2025-03-07 |
Not clear |
| Wei Zhou, Pengqi Li, Wen Meng, Stephanie Hong Zheng, Shixiong Zhang, Shasha Yi, Minghui Gao, Zhengrong Li. Selective sub-nucleus ultrasound stimulation induces synaptic potentiation in the mouse hippocampus. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. vol PP. 2025-03-03. PMID:40031237. |
synaptic plasticity was measured by the slope of field excitatory postsynaptic potentials (fepsps), which were elicited using bipolar electrical stimulation electrodes in the schaffer collaterals of ca3 region and recorded in postsynaptic ca1 neurons using extracellular electrodes. |
2025-03-03 |
2025-03-06 |
mouse |
| Filip P Dybowski, Daniel S Scott, Carol A Tamming. Pharmacological reduction of reverse-translated hippocampal hyperactivity in mouse: relevance for psychosis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2025-02-27. PMID:40016366. |
all animals received one of the four treatments: vehicle (n = 15-24), haloperidol (n = 8-15), xanomeline (n = 8-13) or levetiracetam (n = 6-15) and were subsequently tested for baseline c-fos protein expression within the hippocampal subfields (ca3 and ca1) as a measure of neuronal activity, or tested with the srm task as a measure of social memory. |
2025-02-27 |
2025-03-02 |
mouse |
| Yunlai Zhu, Yongjie Zhao, Junjie Zhang, Xi Sun, Ying Zhu, Xu Zhou, Xuming Shen, Zuyu Xu, Zuheng Wu, Yuehua Da. Memristor-based circuit design of interweaving mechanism of emotional memory in a hippocamp-brain emotion learning model. Neural networks : the official journal of the International Neural Network Society. vol 186. 2025-02-20. PMID:39978138. |
leveraging the hippocampal-brain emotion learning (bel) architecture, the memristive circuit comprises seven comprehensive modules: the thalamus, sensory cortex, orbitofrontal cortex, amygdala, dentate gyrus (dg), ca3, and ca1. |
2025-02-20 |
2025-02-23 |
human |
| David J Horovitz, Laura A Askins, Grace M Regnier, Joseph A McQuai. Age-related synaptic signatures of brain and cognitive reserve in the rat hippocampus and parahippocampal regions. Neurobiology of aging. vol 148. 2025-02-15. PMID:39954409. |
we observed significant age-related reductions in vesicular glutamate transporter vglut1, particularly in the stratum oriens (so), radiatum (sr), and lacunosum-moleculare (slm) of the dorsal ca3 and slm of the dorsal ca1. |
2025-02-15 |
2025-02-18 |
rat |
| David J Horovitz, Laura A Askins, Grace M Regnier, Joseph A McQuai. Age-related synaptic signatures of brain and cognitive reserve in the rat hippocampus and parahippocampal regions. Neurobiology of aging. vol 148. 2025-02-15. PMID:39954409. |
higher levels of the vesicular gaba transporter (vgat) were associated with better spatial learning in older rats, across several synaptic zones of the dorsal hippocampus, including the outer molecular layer of the dentate gyrus (dg), and the so, sr, slm, and pyramidal cell layers of both ca3 and ca1. |
2025-02-15 |
2025-02-18 |
rat |
| Panthea Nemat, Salimat Semenova, Rolinka J van der Loo, August B Smit, Sabine Spijker, Michel C van den Oever, Priyanka Rao-Rui. Structural synaptic signatures of contextual memory retrieval-reactivated hippocampal engram cells. Neurobiology of learning and memory. 2025-02-09. PMID:39923960. |
using a combination of egrasp (enhanced green fluorescent protein (gfp) reconstitution across synaptic partners) and viral-trap (targeted recombination in activated populations) to label ca3 synapses onto ca1 engram cells, we investigated differences in spine density, clusters, and morphology between the reactivated and non-reactivated population of the learning ensemble. |
2025-02-09 |
2025-02-13 |
Not clear |
| Sanggeon Park, Mijeong Park, Eun Joo Kim, Jeansok J Kim, Jeiwon Cho, Yeowool Hu. Distinct disruptions in CA1 and CA3 place cell function in Alzheimer's disease mice. iScience. vol 28. issue 2. 2025-02-06. PMID:39911347. |
these findings elucidate that distinct physiological perturbations in ca1 and ca3 place cells, coupled with disrupted hippocampal theta rhythmicity in ca1, potentially orchestrate the impairment of hippocampal-dependent spatial learning and memory in ad pathogenesis. |
2025-02-06 |
2025-02-08 |
mouse |
| Seyda Koc, Ekin Erdogmus, Ozlem Bozdemir, Deniz Ozkan-Vardar, Unzile Yaman, Pınar Erkekoglu, Naciye Dilara Zeybek, Belma Kocer-Gumuse. Prepubertal phthalate exposure can cause histopathological alterations, DNA methylation and histone acetylation changes in rat brain. Toxicology and industrial health. 2025-01-28. PMID:39873534. |
examining the hippocampus under the light microscope, pyramidal neuron loss was detected only in ca1 of the dehp-l group, while in dehp-h rats, pyramidal neuron losses were detected in the ca1, ca2, and ca3 regions. |
2025-01-28 |
2025-01-30 |
rat |