| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenxi Yu, Sophie F Hill, Limei Zhu, Yiannos Demetriou, Faith Reger, Joanna Mattis, Miriam H Meisle. Dentate gyrus granule cells are a locus of pathology in Scn8a developmental encephalopathy. Neurobiology of disease. 2024-07-05. PMID:38969233. |
targeted reduction of scn8a expression in the dentate gyrus by viral delivery of an shrna resulted in doubling of median survival time from 4 months to 8 months, whereas delivery of shrna to the ca1 and ca3 regions did not result in lengthened survival. |
2024-07-05 |
2024-07-08 |
mouse |
| Shih-Pi Ku, Erika Atucha, Nico Alavi, Halla Mulla-Osman, Rukhshona Kayumova, Motoharu Yoshida, Jozsef Csicsvari, Magdalena M Sauvag. Phase locking of hippocampal CA3 neurons to distal CA1 theta oscillations selectively predicts memory performance. Cell reports. vol 43. issue 6. 2024-07-01. PMID:38814781. |
phase locking of hippocampal ca3 neurons to distal ca1 theta oscillations selectively predicts memory performance. |
2024-07-01 |
2024-07-03 |
rat |
| Nurinee Dolrahman, Wachiryah Thong-As. Beta-sitosterol mitigates cognitive deficit and hippocampal neurodegeneration in mice with trimethyltin-induced toxicity. Experimental animals. 2024-06-30. PMID:38945945. |
the results indicated the massy effect of tmt on induced motor ability and spatial memory deficits in accordance with increased neuronal degeneration in ca1, ca3, and dg and internal capsule white matter damage. |
2024-06-30 |
2024-07-03 |
mouse |
| Nurinee Dolrahman, Wachiryah Thong-As. Beta-sitosterol mitigates cognitive deficit and hippocampal neurodegeneration in mice with trimethyltin-induced toxicity. Experimental animals. 2024-06-30. PMID:38945945. |
both doses of bss treatment exhibited improvement in motor ability and spatial memory deficits in accordance with the activation of reactive astrocytes in ca1, ca3, and dg. |
2024-06-30 |
2024-07-03 |
mouse |
| Ana Paula Rodrigues Martini, Livia Machado Schlemmer, Joelma Alves Lucio Padilha, Rafael Bandeira Fabres, Natividade de Sá Couto Pereira, Lenir Orlandi Pereira, Carla Dalmaz, Carlos Alexandre Nett. Acrobatic training prevents learning impairments and astrocyte remodeling in the hippocampus of rats undergoing chronic cerebral hypoperfusion: sex-specific benefits. Frontiers in rehabilitation sciences. vol 5. 2024-06-28. PMID:38939055. |
we investigated the effects of acrobatic training on astrocyte remodeling in the ca1 and ca3 subfields of the hippocampus and spatial memory impairment in male and female rats at different stages of the two-vessel occlusion (2vo) model. |
2024-06-28 |
2024-06-30 |
rat |
| Matéo N'Diaye, Eva-Gunnel Ducourneau, Ioannis Bakoyiannis, Mylène Potier, Pauline Lafenetre, Guillaume Ferreir. Obesogenic diet induces sex-specific alterations of contextual fear memory and associated hippocampal activity in mice. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 6. 2024-06-27. PMID:38934712. |
compared with females, contextual fear conditioning induced higher neuronal activation in the dorsal and ventral hpc (ca1 and ca3 subfields) as well as in the medial prefrontal cortex in males. |
2024-06-27 |
2024-06-29 |
mouse |
| Jéssica Rabelo Bezerra, Tyciane de Souza Nascimento, Juliete Tavares, Mayara Sandrielly Soares de Aguiar, Maiara Virgínia Viana Maia, Geanne Matos de Andrad. Neuroprotective Effect of Chlorogenic Acid in an Animal Model of Sporadic Alzheimer's Disease Induced by Streptozotocin. Molecular neurobiology. 2024-06-19. PMID:38898198. |
additionally, it prevented bdnf depletion in the prefrontal cortex and hippocampus (ca1, ca3, and dg regions), and mitigated astrogliosis and microgliosis in the prefrontal cortex and hippocampus (ca1, ca3, and dg regions). |
2024-06-19 |
2024-06-22 |
mouse |
| Ding Quan Ng, Casey Hudson, Tracy Nguyen, Sukesh Kumar Gupta, Yong Qin Koh, Munjal M Acharya, Alexandre Cha. Dynamin-1 is a potential mediator in Cancer-Related Cognitive Impairment. bioRxiv : the preprint server for biology. 2024-06-19. PMID:38895481. |
in murine breast cancer-bearing mice receiving chemotherapy, we consistently found a significant decline in dnm1 immunoreactivity in the hippocampal ca1 and ca3 subregions. |
2024-06-19 |
2024-06-21 |
mouse |
| Yu Zheng, Qiwen Liu, Yuhang Zhao, Yenan Qi, Lei Don. Design of a 1 × 4 micro-magnetic stimulation device and its targeted, coordinated regulation on LTP of Schaffer-CA1 in the hippocampus of rats. Methods (San Diego, Calif.). 2024-06-16. PMID:38880432. |
then, a 1 × 4 array μms device is used to perform magnetic stimulation at 70 khz/2 mt/1 min, targeting the ca1, ca3, and dg regions individually with single-point magnetic stimulation; and multi-region magnetic stimulation is applied to the double-point targeting regions of ca1-ca3, ca1-dg, and ca3-dg, as well as the triple-point targeting region of ca1-ca3-dg, so as to investigate the regulation of ltp by single-region magnetic stimulation and multi-region magnetic stimulation. |
2024-06-16 |
2024-06-19 |
rat |
| Yu Zheng, Qiwen Liu, Yuhang Zhao, Yenan Qi, Lei Don. Design of a 1 × 4 micro-magnetic stimulation device and its targeted, coordinated regulation on LTP of Schaffer-CA1 in the hippocampus of rats. Methods (San Diego, Calif.). 2024-06-16. PMID:38880432. |
the experimental results indicate that, in the case of single-region magnetic stimulation, the magnitude of the increase in ltp in the ca1 region is the greatest, followed by the ca3 region, while the effect of magnetic stimulation on the dg region is less pronounced. |
2024-06-16 |
2024-06-19 |
rat |
| Motosada Iwase, Kamran Diba, Eva Pastalkova, Kenji Mizusek. Dynamics of spike transmission and suppression between principal cells and interneurons in the hippocampus and entorhinal cortex. Hippocampus. 2024-06-14. PMID:38874439. |
the spike transmission probability of pc-int excitatory pairs that showed short-term depression versus short-term facilitation was higher in ca1 and lower in ca3. |
2024-06-14 |
2024-06-16 |
rat |
| Motosada Iwase, Kamran Diba, Eva Pastalkova, Kenji Mizusek. Dynamics of spike transmission and suppression between principal cells and interneurons in the hippocampus and entorhinal cortex. Hippocampus. 2024-06-14. PMID:38874439. |
likewise, the intersomatic distance affected the proportion of pc-int excitatory pairs that showed short-term depression and facilitation in the opposite manner in ca1 compared with ca3. |
2024-06-14 |
2024-06-16 |
rat |
| Motosada Iwase, Kamran Diba, Eva Pastalkova, Kenji Mizusek. Dynamics of spike transmission and suppression between principal cells and interneurons in the hippocampus and entorhinal cortex. Hippocampus. 2024-06-14. PMID:38874439. |
the time constant of depression was longer, while that of facilitation was shorter in mec than in ca1 and ca3. |
2024-06-14 |
2024-06-16 |
rat |
| Ana Dias-Carvalho, Mariana Ferreira, Ana Reis-Mendes, Rita Ferreira, Maria de Lourdes Bastos, Eduarda Fernandes, Susana Isabel Sá, João Paulo Capela, Félix Carvalho, Vera Marisa Cost. Doxorubicin-induced neurotoxicity differently affects the hippocampal formation subregions in adult mice. Heliyon. vol 10. issue 11. 2024-06-13. PMID:38868005. |
finally, phosphorylation of tau decreased with the highest dox dose in dg and ca3, while tnf-α levels increased in ca1 of dox18. |
2024-06-13 |
2024-06-15 |
mouse |
| Sharif Jabra, Michael Rietsche, Julia Muellerleile, Aet O'Leary, David A Slattery, Thomas Deller, Meike Fellen. Sex- and cycle-dependent changes in spine density and size in hippocampal CA2 neurons. Scientific reports. vol 14. issue 1. 2024-05-28. PMID:38806649. |
while sex- and cycle-dependent differences in dendritic spine density and morphology have been found in the rodent ca1 region, but not in the ca3 or the dentate gyrus, comparable structural data on ca2, i.e. |
2024-05-28 |
2024-06-02 |
mouse |
| Fares J P Sayegh, Lionel Mouledous, Catherine Macri, Juliana Pi Macedo, Camille Lejards, Claire Rampon, Laure Verret, Lionel Daha. Ventral tegmental area dopamine projections to the hippocampus trigger long-term potentiation and contextual learning. Nature communications. vol 15. issue 1. 2024-05-21. PMID:38773091. |
here, we used optogenetic manipulation of midbrain dopamine neurons in male dat::cre mice, and discovered that stimulating the schaffer collaterals - the glutamatergic axons connecting ca3 and ca1 regions - of the dorsal hippocampus concomitantly with midbrain dopamine terminals within a 200 millisecond time-window triggers ltp at glutamatergic synapses. |
2024-05-21 |
2024-05-27 |
mouse |
| Linda Bean, Prodip K Bose, Asha Rani, Ashok Kuma. Serine racemase expression profile in the prefrontal cortex and hippocampal subregions during aging in male and female rats. Aging. vol 16. 2024-05-18. PMID:38761177. |
however, age-associated changes in sr expression levels in the medial and lateral prefrontal cortex (mpfc, lpfc), and in the dorsal hippocampal subfields, ca1, ca3, and dentate gyrus (dg), have not been thoroughly elucidated. |
2024-05-18 |
2024-05-27 |
rat |
| Cansu Bilister Egilmez, Burcu Azak Pazarlar, Mumin Alper Erdogan, Yiğit Uyanikgil, Oytun Erba. Choline chloride shows gender-dependent positive effects on social deficits, learning/memory impairments, neuronal loss and neuroinflammation in the lipopolysaccharide-induced rat model of autism. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2024-05-09. PMID:38721665. |
histologically, significant changes in terms of gliosis were detected in hippocampal ca1 and ca3 regions and cerebellum in choline chloride-treated groups. |
2024-05-09 |
2024-05-27 |
rat |
| Dan Huang, Yunhui Fan, Jingjun Zhang, Qianfeng Wang, Ming Ding, Ruiqing Hou, Kewei Yu, Xiao Xiao, Yi Wu, Junfa W. Dorsal dentate gyrus mediated enriched environment-induced anxiolytic and antidepressant effects in cortical infarcted mice. Experimental neurology. 2024-04-30. PMID:38685308. |
compared to the mice housing in a standard environment, those subjected to acute ee stimulation had significantly increased alff and reho values in the bilateral somatosensory cortex (s1, s2), dorsal dentate gyrus (ddg), dorsal ca1 of hippocampus (dca1), lateral habenular nucleus (lhb), periaqueductal gray (pag), ipsilateral primary motor cortex (m1), retrosplenial cortex (rsc), parietal association cortex (pta), dorsal ca3 of hippocampus (dca3), claustrum (cl), ventral pallidum (vp), amygdala (amy), and contralateral auditory cortex (au). |
2024-04-30 |
2024-05-03 |
mouse |
| Zhu Wang, Bowen Li, Jingrui Yang, Ying Gao, Liu Gao, Qiang Jia, Li Yu, Yunzhi Lin. ML365 ameliorates postoperative cognitive impairment in aged mice by inhibiting NLRP3 inflammasome activation in the hippocampus. Brain research. 2024-04-25. PMID:38663469. |
ml365 pretreatment also reduced nlrp3, caspase-1, asc and il-1β expression levels in the hippocampus, improved pocd-induced pathological changes in the hippocampal ca1 and ca3 areas of aged mice, and decreased levels of plasma mda and oxidative stress. |
2024-04-25 |
2024-04-28 |
mouse |