| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Didem Dönmez Aydin, Oğuz Taşkınalp, Enis Uluçam, Hakan Karadağ, Gülnur Kızılay Özfidan, Ruhan Topuz, Onur Erso. The Effect of Acute and Chronic Formaldehyde Exposure on Learning and Memory in Male and Female Rats. The International journal of neuroscience. 2023-12-28. PMID:38152865. |
after acute exposure, apoptosis was observed in the hippocampal ca1 and ca3 regions in males. |
2023-12-28 |
2023-12-30 |
rat |
| Changjian Wan, Xueqing Song, Zhuyu Zhang, Wenxiang Hu, Yanhua Chen, Wei Sun, Zhibin Liu, Songhua Wang, Wei Men. Voluntary exercise during puberty promotes spatial memory and hippocampal DG/CA3 synaptic transmission in mice. Cerebral cortex (New York, N.Y. : 1991). 2023-12-21. PMID:38124544. |
in addition, there was an increase in the expression of nr2a/nr2b subunits of n-methyl-d-aspartate receptors and α1gabaa subunit of gamma-aminobutyric acid type a receptors, as well as dendritic spine density, specifically within dentate gyrus and ca3 regions rather than ca1 region. |
2023-12-21 |
2023-12-23 |
mouse |
| Changjian Wan, Xueqing Song, Zhuyu Zhang, Wenxiang Hu, Yanhua Chen, Wei Sun, Zhibin Liu, Songhua Wang, Wei Men. Voluntary exercise during puberty promotes spatial memory and hippocampal DG/CA3 synaptic transmission in mice. Cerebral cortex (New York, N.Y. : 1991). 2023-12-21. PMID:38124544. |
the findings suggest that voluntary exercise during development can enhance spatial memory in mice by increasing synapse numbers and improving synaptic transmission in hippocampal dentate gyrus and ca3 regions, but not in ca1 region. |
2023-12-21 |
2023-12-23 |
mouse |
| Chao Song, Zixu Wang, Jing Cao, Yulan Dong, Yaoxing Che. Hesperetin protects hippocampal neurons from the neurotoxicity of Aflatoxin B1 in mice. Ecotoxicology and environmental safety. vol 269. 2023-12-06. PMID:38056121. |
our findings demonstrated that afb1 increased the levels of bax and cleaved-caspase3 proteins, while decreasing the levels of bcl2 protein in the ca1 and ca3 regions of the hippocampus. |
2023-12-06 |
2023-12-10 |
mouse |
| Etienne Aumont, Aurélie Bussy, Marc-André Bedard, Gleb Bezgin, Joseph Therriault, Melissa Savard, Jaime Fernandez Arias, Viviane Sziklas, Paolo Vitali, Nina Margherita Poltronetti, Vanessa Pallen, Emilie Thomas, Serge Gauthier, Eliane Kobayashi, Nesrine Rahmouni, Jenna Stevenson, Cecile Tissot, Mallar M Chakravarty, Pedro Rosa-Net. Hippocampal subfield associations with memory depend on stimulus modality and retrieval mode. Brain communications. vol 5. issue 6. 2023-11-30. PMID:38035364. |
we segmented the right and left hippocampi into (i) dentate gyrus and cornu ammonis 4 (dg/ca4); (ii) ca2 and ca3 (ca2/ca3); (iii) ca1; (iv) strata radiatum, lacunosum and moleculare; and (v) subiculum. |
2023-11-30 |
2023-12-10 |
human |
| Katy E Pannoni, Quentin S Fischer, Renesa Tarannum, Mikel L Cawley, Mayd M Alsalman, Nicole Acosta, Chisom Ezigbo, Daniela V Gil, Logan A Campbell, Shannon Farri. The mitochondrial calcium uniporter is necessary for synaptic plasticity and proper mitochondrial morphology and distribution in the distal dendrites of CA2 neurons. bioRxiv : the preprint server for biology. 2023-11-24. PMID:37986798. |
intriguingly, mcu is uniquely enriched in ca2 distal dendrites relative to neighboring ca1 or ca3 distal dendrites, suggesting mitochondria there are molecularly distinct. |
2023-11-24 |
2023-11-28 |
mouse |
| Kevin S Chen, Mohamed H Noureldein, Diana M Rigan, John M Hayes, Masha G Savelieff, Eva L Feldma. Regional interneuron transcriptional changes reveal pathologic markers of disease progression in a mouse model of Alzheimer's disease. bioRxiv : the preprint server for biology. 2023-11-14. PMID:37961679. |
to determine the underlying pathologic processes involved in interneuron dysfunction, we spatially profiled the brain transcriptome of the 5xfad ad mouse model versus controls, across four brain regions, dentate gyrus, hippocampal ca1 and ca3, and cortex, at early-stage (12 weeks-of-age) and late-stage (30 weeks-of-age) disease. |
2023-11-14 |
2023-11-20 |
mouse |
| Shilin Xu, Keke Hao, Ying Xiong, Rui Xu, Huan Huang, Huiling Wan. Capsaicin alleviates neuronal apoptosis and schizophrenia-like behavioral abnormalities induced by early life stress. Schizophrenia (Heidelberg, Germany). vol 9. issue 1. 2023-11-07. PMID:37935716. |
ms decreased the expression of trpv1 in the frontal association cortex (fra) and in the hippocampal ca1, ca3, and dentate gyrus (dg) regions compared with the control group resulting in the increase of pro-apoptotic proteins (bax, caspase3, cleaved-caspase3) and the decrease of anti-apoptotic proteins (bcl-2). |
2023-11-07 |
2023-11-20 |
human |
| Adriana M Zago, Fabiano B Carvalho, Francine L Rahmeier, Marta Santin, Giuliano R Guimarães, Jessié M Gutierres, Marilda da C Fernande. Exendin-4 Prevents Memory Loss and Neuronal Death in Rats with Sporadic Alzheimer-Like Disease. Molecular neurobiology. 2023-11-03. PMID:37919602. |
stz reduced mature neuron density (neun) and increased cell apoptosis (cc3) in the dg, ca1, and ca3. |
2023-11-03 |
2023-11-08 |
rat |
| Octavio Fabián Mercado-Gómez, Virginia Selene Arriaga-Ávila, Angélica Vega-García, Sandra Orozco-Suarez, Vadim Pérez-Koldenkova, Juan José Camarillo-Sánchez, Marcelino Álvarez-Herrera, Rosalinda Guevara-Guzmá. Daytime-Restricted Feeding Ameliorates Oxidative Stress by Increasing NRF2 Transcriptional Factor in the Rat Hippocampus in the Pilocarpine-Induced Acute Seizure Model. Brain sciences. vol 13. issue 10. 2023-10-30. PMID:37891811. |
the cellular distribution of the nrf2 and sod2 proteins in the pyramidal cell layer of both the ca1 and ca3 hippocampal subfields and astrocytes (gfap marker) were quantified using immunofluorescence and immunohistochemistry, respectively. |
2023-10-30 |
2023-11-08 |
rat |
| Roya Homayouni, Kelsey L Canada, Samaah Saifullah, Da' Jonae Foster, Charlotte Thill, Naftali Raz, Ana M Daugherty, Noa Ofe. Age-related differences in hippocampal subfield volumes across the human lifespan: A meta-analysis. Hippocampus. 2023-10-26. PMID:37881160. |
limited evidence suggests that dg and ca3 volumes differ across development while other regions remain relatively stable, and studies of adulthood implicate a downward trend in all subfield volumes with prominent age effects on ca1. |
2023-10-26 |
2023-11-08 |
human |
| Ye Huang, Min Han, Qifeng Shi, Xuewang Li, Jiajia Mo, Yan Liu, Zhaoxing Chu, Weizu L. Li, P HY-021068 alleviates cerebral ischemia-reperfusion injury by inhibiting NLRP1 inflammasome and restoring autophagy function in mice. Experimental neurology. 2023-10-26. PMID:37884189. |
hy-021065 and nlrp1 knockdown significantly ameliorated the pathological damage and increased psd-95 expression in the cortex and hippocampus ca1 and ca3 regions. |
2023-10-26 |
2023-11-08 |
mouse |
| Jean Philippe Djientcheu Tientcheu, Florence Tsofack Ngueguim, Racéline Kamkumo Gounoue, Michel Arnaud Mbock, Rodrigue Ngapout, Antoine Kavaye Kandeda, Théophile Dim. The extract of Sclerocarya birrea, Nauclea latifolia, and Piper longum mixture ameliorates diabetes-associated cognitive dysfunction. Metabolic brain disease. 2023-10-11. PMID:37821784. |
fructose/stz administration resulted in t2d, impaired short- and long-term memory, significantly increased oxidative/nitrative stress, pro-inflammatory cytokine levels, acetylcholinesterase activity (ache), hippocampal neuronal loss and degeneration in ca1 and ca3 subfields, and neuronal vacuolation in dg. |
2023-10-11 |
2023-10-15 |
rat |
| Εvgenia Dandi, Paschalis Theotokis, Maria Christina Petri, Vaia Sideropoulou, Evangelia Spandou, Despina A Tat. Environmental enrichment initiated in adolescence restores the reduced expression of synaptophysin and GFAP in the hippocampus of chronically stressed rats in a sex-specific manner. Developmental psychobiology. vol 65. issue 7. 2023-10-05. PMID:37796476. |
syn and gfap expressions were evaluated in ca1 and ca3 subfields and dentate gyrus (dg). |
2023-10-05 |
2023-10-07 |
rat |
| Εvgenia Dandi, Paschalis Theotokis, Maria Christina Petri, Vaia Sideropoulou, Evangelia Spandou, Despina A Tat. Environmental enrichment initiated in adolescence restores the reduced expression of synaptophysin and GFAP in the hippocampus of chronically stressed rats in a sex-specific manner. Developmental psychobiology. vol 65. issue 7. 2023-10-05. PMID:37796476. |
cus reduced the expression of syn in all hippocampal areas, whereas lower gfap expression was evident only in ca1 and ca3. |
2023-10-05 |
2023-10-07 |
rat |
| Εvgenia Dandi, Paschalis Theotokis, Maria Christina Petri, Vaia Sideropoulou, Evangelia Spandou, Despina A Tat. Environmental enrichment initiated in adolescence restores the reduced expression of synaptophysin and GFAP in the hippocampus of chronically stressed rats in a sex-specific manner. Developmental psychobiology. vol 65. issue 7. 2023-10-05. PMID:37796476. |
the reduced expression of syn in dg and ca3 was evident to male sh/cus rats, whereas the reduced gfap expression in ca1 and ca3 was limited to sh/cus females. |
2023-10-05 |
2023-10-07 |
rat |
| Ruiyi Chen, Yash S Vakilna, Samuel Brandon Lassers, William C Tang, Gregory J Brewe. Hippocampal network axons respond to patterned theta burst stimulation with lower activity of initially higher spike train similarity from EC to DG and later similarity of axons from CA1 to EC. Journal of neural engineering. 2023-09-04. PMID:37666242. |
the four chambers were plated separately with entorhinal cortex (ec), dentate gyrus (dg), ca1, and ca3 neurons. |
2023-09-04 |
2023-09-07 |
Not clear |
| Ruiyi Chen, Yash S Vakilna, Samuel Brandon Lassers, William C Tang, Gregory J Brewe. Hippocampal network axons respond to patterned theta burst stimulation with lower activity of initially higher spike train similarity from EC to DG and later similarity of axons from CA1 to EC. Journal of neural engineering. 2023-09-04. PMID:37666242. |
this time-dependent response suggested that ca3 encoded temporal information and axons transmitted the information to ca1. |
2023-09-04 |
2023-09-07 |
Not clear |
| Parvaneh Mohseni-Moghaddam, Hossein Khaleghzadeh-Ahangar, Rabi Atabak. Role of Necroptosis, a Regulated Cell Death, in Seizure and Epilepsy. Neurochemical research. 2023-08-30. PMID:37646959. |
these responses involve the activation of neurons and astrocytes, consequently leading to an increase in the expression levels of proteins and genes such as rip1, rip3, and mlkl in a time-dependent manner in regions such as the hippocampus (ca1, ca3, dentate gyrus, and hilus), piriform cortex, and amygdala. |
2023-08-30 |
2023-09-07 |
Not clear |
| Alexander C Whitebirch, Bina Santoro, Anastasia Barnett, Christos Panagiotis Lisgaras, Helen E Scharfman, Steven A Siegelbau. Reduced cholecystokinin-expressing interneuron input contributes to disinhibition of the hippocampal CA2 region in a mouse model of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-08-29. PMID:37643861. |
a significant proportion of temporal lobe epilepsy (tle) patients experience drug-resistant seizures associated with mesial temporal sclerosis, in which there is extensive cell loss in the hippocampal ca1 and ca3 subfields, with a relative sparing of dentate gyrus granule cells and ca2 pyramidal neurons (pns). |
2023-08-29 |
2023-09-07 |
mouse |