Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Mohammadmehdi Hadipour, Soheila Refahi, Zohreh Jangravi, Gholam Hossein Meftah. Tarooneh extract relieves anxiety-like behaviors and cognitive deficits by inhibiting synaptic loss in the hippocampus and frontal cortex in rats subjected to chronic restraint stress. 3 Biotech. vol 13. issue 5. 2023-05-08. PMID:37152003. |
golgi-cox staining indicates that loss of neural spine density in dg, ca1, ca3, and frontal cortex due to chronic restraint stress, was prevented with daily administration of tarooneh. |
2023-05-08 |
2023-08-14 |
rat |
Mohammadmehdi Hadipour, Soheila Refahi, Zohreh Jangravi, Gholam Hossein Meftah. Tarooneh extract relieves anxiety-like behaviors and cognitive deficits by inhibiting synaptic loss in the hippocampus and frontal cortex in rats subjected to chronic restraint stress. 3 Biotech. vol 13. issue 5. 2023-05-08. PMID:37152003. |
in conclusion, our results suggest that tarooneh prevented and improved anxiety-like behavior, cognitive deficit, and neuronal damages in the ca1, ca3, and dg regions of the hippocampus and frontal cortex neurons induced by chronic restraint stress. |
2023-05-08 |
2023-08-14 |
rat |
F A Concepcion, N A Ekstrom, M N Khan, O O Estes, N P Poolo. Progressive Dysregulation of Tau Phosphorylation in an Animal Model of Temporal Lobe Epilepsy. Neuroscience. 2023-05-04. PMID:37142182. |
in the whole hippocampal formation from four month post-se rats, total tau expression had reverted to normal, but there was a significant reduction in s202/t205 tau phosphorylation levels that was also seen in ca1 and ca3. |
2023-05-04 |
2023-08-14 |
human |
Jiaxin Zheng, Hong Zhu, Zhenyu Zhao, Miaoyu Du, Zhitian Wang, Liuyi Lan, Junjian Zhan. Vesicular acetylcholine transporter in the basal forebrain improves cognitive impairment in chronic cerebral hypoperfusion rats by modulating theta oscillations in the hippocampus. Neuroscience letters. 2023-04-29. PMID:37120008. |
moreover, vacht overexpression increased hippocampal cholinergic levels, improved theta oscillations, and improved the synchrony of theta oscillations between ca1 and ca3 in cch rats. |
2023-04-29 |
2023-08-14 |
rat |
Claudia Sîrbe, Medeea Badii, Tania O Crişan, Gabriel Bența, Alina Grama, Leo A B Joosten, Simona Rednic, Tudor Lucian Po. Detection of Novel Biomarkers in Pediatric Autoimmune Hepatitis by Proteomic Profiling. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108648. |
the proteins that showed variable expression include ca1, ca3, gas6, fcgr2a, 4e-bp1 and ccl19, which may serve as potential biomarkers for patients with aih. |
2023-04-28 |
2023-08-14 |
Not clear |
B M Romero-Torres, Y A Alvarado-Ramírez, S R Duran-Alonzo, A E Ruiz-Contreras, A Herrera-Solis, O Amancio-Belmont, O E Prospéro-García, M Méndez-Día. A potential role of hippocampus on impulsivity and alcohol consumption though CB1R. Pharmacology, biochemistry, and behavior. 2023-04-23. PMID:37088449. |
to further understand the potential role of the hippocampal cb1r in impulsive and drug seeking behaviors, we characterized impulsivity in adolescent and adult male rats, by means of a delay discounting task (ddt) by evaluating preference and seeking motivation for alcohol (10 % v/v) consumption, and analyzing cb1r expression in ca1, ca3 and the dentate gyrus (dg) of the hpp as well as in the medial prefrontal cortex (mpfc). |
2023-04-23 |
2023-08-14 |
rat |
N H Harbin, D J Lustberg, C Hurst, J Pare, K M Crotty, A L Waters, S M Yeligar, Y Smith, N T Seyfried, D Weinshenker, J R Heple. RGS14 limits seizure-induced mitochondrial oxidative stress and pathology in hippocampus. Neurobiology of disease. 2023-04-19. PMID:37075948. |
previous findings show that, unlike pcs of hippocampal areas ca1 and ca3, ca2 pcs are resistant to a number of neurological insults, including degeneration caused by temporal lobe epilepsy (tle). |
2023-04-19 |
2023-08-14 |
mouse |
Marília da Cunha Feio Leal, Fabio Leite do Amaral Junior, Bernardo Freire da Silva Arruda, Juliana Ayumi Azevedo Kurosawa, Amanda Almeida Vieira, Júlia Corrêa Campos Maia, Viviana Virgínia Bezerra Scalfoni, Antonio Morais da Silveira Junior, Matheus Oliveira Feijó, Fernanda Beatriz Araújo de Albuquerque, Maria Helena Moutinho Marta, Marina Paula Nobre Normando, Alana Gabriele Oliveira Cabeça da Silva, Fernanda Catharina Pires da Trindade, Fabíola de Carvalho Chaves de Siqueira Mendes, Marcia Consentino Kronka Sosthene. The Masticatory Activity Interference in Quantitative Estimation of CA1, CA3 and Dentate Gyrus Hippocampal Astrocytes of Aged Murine Models and under Environmental Stimulation. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047502. |
thus, considering this context, the present study evaluated the effects of deprivation and rehabilitation of masticatory activity, aging, and environmental enrichment on the stereological quantification of hippocampal astrocytes from layers ca1, ca3, and dg. |
2023-04-13 |
2023-08-14 |
mouse |
Bryan A Adriaanse, Sinead Brady, Minghui Wang, Daniel J Beard, Jonathan I Spencer, Jonathan Pansieri, Brad A Sutherland, Margaret M Esiri, Alastair M Buchan, Zameel Cader, Bin Zhang, Gabriele C DeLuc. Tuberous Sclerosis Complex-1 (TSC1) contributes to selective neuronal vulnerability in Alzheimer's Disease. Neuropathology and applied neurobiology. 2023-04-06. PMID:37020385. |
we interrogated the expression of tuberous sclerosis complex-1 (tsc1; hamartin) and mtor-related proteins in hippocampal ca1 and ca3 subfields. |
2023-04-06 |
2023-08-14 |
Not clear |
Michael Nugent, Mark St Pierre, Ashley Brown, Salma Nassar, Pritika Parmar, Yuma Kitase, Sarah Ann Duck, Charles Pinto, Lauren Jantzie, Camille Fung, Raul Chavez-Valde. Sexual dimorphism in the closure of the hippocampal postnatal critical period of synaptic plasticity after intrauterine growth restriction - link to oligodendrocyte and glial dysregulation. Developmental neuroscience. 2023-04-05. PMID:37019088. |
pnn volumes were smaller in ca1 and ca3 of iugr female mice along with pnn intensity in ca3 but they had larger volumes in the ca3 of iugr male mice. |
2023-04-05 |
2023-08-14 |
mouse |
Michael Nugent, Mark St Pierre, Ashley Brown, Salma Nassar, Pritika Parmar, Yuma Kitase, Sarah Ann Duck, Charles Pinto, Lauren Jantzie, Camille Fung, Raul Chavez-Valde. Sexual dimorphism in the closure of the hippocampal postnatal critical period of synaptic plasticity after intrauterine growth restriction - link to oligodendrocyte and glial dysregulation. Developmental neuroscience. 2023-04-05. PMID:37019088. |
reactive astrocytes denoted by gfap areas, volumes, lengths, and numbers of branching were increased in iugr female ca1 but in iugr male ca3 compared to sex-matched shams. |
2023-04-05 |
2023-08-14 |
mouse |
Michael Nugent, Mark St Pierre, Ashley Brown, Salma Nassar, Pritika Parmar, Yuma Kitase, Sarah Ann Duck, Charles Pinto, Lauren Jantzie, Camille Fung, Raul Chavez-Valde. Sexual dimorphism in the closure of the hippocampal postnatal critical period of synaptic plasticity after intrauterine growth restriction - link to oligodendrocyte and glial dysregulation. Developmental neuroscience. 2023-04-05. PMID:37019088. |
lastly, activated microglia was only detected in iugr female ca1 and ca3 sub-regions. |
2023-04-05 |
2023-08-14 |
mouse |
Nan Zhu, Yiyuan Zhang, Xi Xiao, Yimeng Wang, Jiajia Yang, Laura Lee Colgin, Chenguang Zhen. Hippocampal oscillatory dynamics in freely behaving rats during exploration of social and non-social stimuli. Cognitive neurodynamics. vol 17. issue 2. 2023-04-03. PMID:37007194. |
we recorded local field potentials from hippocampal subfields ca1, ca2, and ca3 of 4 rats performing a social exploration task. |
2023-04-03 |
2023-08-14 |
rat |
b' Sinan Saral, Atilla Top\\xc3\\xa7u, Mehmet Alkanat, Tolga Mercantepe, Zafer \\xc5\\x9eahin, Kerimali Aky\\xc4\\xb1ld\\xc4\\xb1z, Kader Semra Karata\\xc5\\x9f, Lamiye Y\\xc4\\xb1ld\\xc4\\xb1z, Levent T\\xc3\\xbcmkaya, Zihni A\\xc3\\xa7ar Yaz\\xc4\\xb1c\\xc4\\xb. Agomelatine attenuates cisplatin-induced cognitive impairment via modulation of BDNF/TrkB signaling in rat hippocampus. Journal of chemical neuroanatomy. 2023-03-31. PMID:37001681.' |
histological findings showed that agomelatine treatment reduced pyramidal neuron damage in hippocampal dg, ca1 and ca3. |
2023-03-31 |
2023-08-14 |
rat |
b' Sinan Saral, Atilla Top\\xc3\\xa7u, Mehmet Alkanat, Tolga Mercantepe, Zafer \\xc5\\x9eahin, Kerimali Aky\\xc4\\xb1ld\\xc4\\xb1z, Kader Semra Karata\\xc5\\x9f, Lamiye Y\\xc4\\xb1ld\\xc4\\xb1z, Levent T\\xc3\\xbcmkaya, Zihni A\\xc3\\xa7ar Yaz\\xc4\\xb1c\\xc4\\xb. Agomelatine attenuates cisplatin-induced cognitive impairment via modulation of BDNF/TrkB signaling in rat hippocampus. Journal of chemical neuroanatomy. 2023-03-31. PMID:37001681.' |
cisplatin increased nnos and trkb positivity in dg, ca1 and ca3 neurons compared to control. |
2023-03-31 |
2023-08-14 |
rat |
Laura J Mahady, Sylvia E Perez, Michael Malek-Ahmadi, Elliott J Mufso. Oligomeric, phosphorylated, and truncated tau and spliceosome pathology within the entorhinal-hippocampal connectome across stages of Alzheimer's disease. The Journal of comparative neurology. 2023-03-29. PMID:36989381. |
although a significant increase in toc1, tnt1, and at8 neuron density occurred in the ec in mci and ad, subicular, dg granule cell, and ca1 and ca3 densities were only significantly higher in ad. |
2023-03-29 |
2023-08-14 |
human |
Anamika, Anima Roy, Surendra K Trigu. Hippocampus mitochondrial MnSOD activation by a SIRT3 activator, honokiol, correlates with its deacetylation and upregulation of FoxO3a and PGC1α in a rat model of ammonia neurotoxicity. Journal of cellular biochemistry. 2023-03-16. PMID:36922709. |
this was consistent with the reduced level of immuno-stained foxo3a and pgc1α proteins in hippocampus dg, ca1 and ca3 regions of those mohe rats. |
2023-03-16 |
2023-08-14 |
rat |
Alfonso Díaz, Rubén Vázquez-Roque, Karen Carreto-Meneses, Diana Moroni-González, José Albino Moreno-Rodríguez, Samuel Treviñ. Polyoxidovanadates as a pharmacological option against brain aging. Journal of chemical neuroanatomy. 2023-03-15. PMID:36921908. |
pov treatments reduced nrf2 and gfap immunoreactivity in ca1 (70% - 87.5%), ca3 (60% - 80%), and dg (57% - 89%). |
2023-03-15 |
2023-08-14 |
rat |
Xiao-Qing Cen, Ping Li, Bo Wang, Xing Chen, Yan Zhao, Nan Yang, Yan Peng, Chang-Hong Li, Ya-Lei Ning, Yuan-Guo Zho. Knockdown of adenosine A2A receptors in hippocampal neurons prevents post-TBI fear memory retrieval. Experimental neurology. 2023-03-12. PMID:36907351. |
our finding showed (i) tbi enhanced mice freezing levels (fear memory) at seven days post-tbi; (ii) the a2ar agonist cgs21680 enhanced the post-tbi freezing levels; conversely, the a2ar antagonist zm241385 reduced mice freezing level; further (iii) genetic knockdown of neuronal a2ar in the hippocampal ca1, ca3, and dg regions reduced post-tbi freezing levels, while a2ar knockout in dg region yielded the most reduction in fear memory; finally, (iv) aav-camkii-cre virus-mediated dg deletion of a2ar on excitatory neurons led to a significant decreased freezing levels post-tbi. |
2023-03-12 |
2023-08-14 |
mouse |
Diego A González-Franco, Rogelio Pegueros-Maldonado, América M Cruz-Quiroz, Norma Serafín, Paola C Bello-Medina, Roberto A Prado-Alcalá, Gina L Quirart. Intense inhibitory avoidance training increases nuclear-phosphorylated glucocorticoid receptors in neurons of CA1 of hippocampus and ventral caudate putamen. Brain research. 2023-03-11. PMID:36906227. |
the gr is present in the hippocampus with a high concentration in ca1 and dentate gyrus (dg), and a smaller proportion in ca3, and sparsely present in the caudate putamen (cpu); both structures are involved in memory consolidation of ia. |
2023-03-11 |
2023-08-14 |
rat |