| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicholas M DiCola, Alexa L Lacy, Omar J Bishr, Kathryn M Kimsey, Jenna L Whitney, Sarah D Lovett, Sara N Burke, Andrew P Maure. Advanced age has dissociable effects on hippocampal CA1 ripples and CA3 high frequency events in male rats. Neurobiology of aging. vol 117. 2022-06-07. PMID:35665647. |
sharp wave/ripples/high frequency events (hfes) are transient bursts of depolarization in hippocampal subregions ca3 and ca1 that occur during rest and pauses in behavior. |
2022-06-07 |
2023-08-14 |
rat |
| Ryuki Tsuchida, Taisei Yamaguchi, Daisuke Funabashi, Yusuke Koumi, Ichiro Kita, Takeshi Nishijim. Exercise type influences the effect of an acute bout of exercise on hippocampal neuronal activation in mice. Neuroscience letters. 2022-06-06. PMID:35660647. |
immunohistochemical examination of c-fos, a marker of neuronal activation, revealed that treadmill exercise at 15 m/min (t15) significantly increased c-fos expression in all subfields of the hippocampus (dentate gyrus dg, ca1, ca3), but rotarod exercise at 30 rpm (r30) did not, as compared with the respective control groups. |
2022-06-06 |
2023-08-14 |
mouse |
| Lace M Riggs, Scott M Thompson, Todd D Goul. (2R,6R)-hydroxynorketamine rapidly potentiates optically-evoked Schaffer collateral synaptic activity. Neuropharmacology. 2022-06-06. PMID:35661657. |
this potentiation is mediated in part by an increase in glutamate release probability, as (2r,6r)-hnk suppressed paired-pulse facilitation at ca3 projections, an effect that correlated with the magnitude of the (2r,6r)-hnk-induced potentiation of ca1 activity. |
2022-06-06 |
2023-08-14 |
rat |
| Ashif Iqubal, Mohammad Kashif Iqubal, Sumit Sharma, Mohd Wasim, Mohamed A Alfaleh, Shadab Md, Sanjula Baboota, Javed Ali, Syed Ehtaishamul Haqu. Pathogenic mechanisms and therapeutic promise of phytochemicals and nanocarriers based drug delivery against radiotherapy-induced neurotoxic manifestations. Drug delivery. vol 29. issue 1. 2022-05-11. PMID:35543534. |
based on the preclinical and clinical investigations, the profound role of increased oxidative stress, nuclear translocation of nf-kb, production of proinflammatory cytokines such as tnf-α, il-6, il-β, increased level of mmps, increased apoptosis, reduced angiogenesis, neurogenesis, and histological aberrations in ca1, ca2, ca3 and dg region of the hippocampus have been reported. |
2022-05-11 |
2023-08-13 |
Not clear |
| Lennart Seizer, Sadegh Rahimi, Sandra Santos-Sierra, Meinrad Drexe. Expression of toll like receptor 8 (TLR8) in specific groups of mouse hippocampal interneurons. PloS one. vol 17. issue 5. 2022-05-04. PMID:35507634. |
somatostatin-positive interneurons co-expressing tlr8 were mainly present in hippocampal sector ca3 but rare in the dentate gyrus and ca1. |
2022-05-04 |
2023-08-13 |
mouse |
| Irina V Romanova, Elena V Mikhailova, Anastasiya L Mikhrina, Alexander O Shpako. Type 1 melanocortin receptors in pro-opiomelanocortin-, vasopressin-, and oxytocin-immunopositive neurons in different areas of mouse brain. Anatomical record (Hoboken, N.J. : 2007). 2022-04-27. PMID:35475324. |
using double immunolabeling, the mc1rs were visualized on the surface and in the bodies and outgrowths of pro-opiomelanocortin (pomc)-immunopositive neurons in the hypothalamic arcuate nucleus, nts, hippocampal ca3 and ca1 regions, and cerebral cortex. |
2022-04-27 |
2023-08-13 |
mouse |
| Era Seth, Mani Chopr. Neuroprotective efficacy of berberine following developmental exposure to chlorpyrifos in F1 generation of Wistar rats: Apoptosis-autophagy interplay. The Science of the total environment. 2022-04-19. PMID:35439518. |
our results demonstrated that cpf intoxication instigated cognitive and neurobehavioral impairment, oxidant-antioxidant imbalance, and histomorphological alterations in ca1, ca3, and dg regions of the offsprings. |
2022-04-19 |
2023-08-13 |
rat |
| Zuko Mpisana, Ishmael Festus Jaja, Charles Byaruhanga, Munyaradzi Christopher Maruf. Body condition scores, fluke intensity, liver pathology, and carcass quality of different dairy cattle genotypes infected with Fasciola species at high throughput abattoirs in South Africa. Parasitology research. 2022-04-02. PMID:35366098. |
a longitudinal study was conducted from september 2019 to october 2020 to determine body condition score, liver fluke intensity, liver pathology in 3065 dairy cattle slaughtered in ca1, ca2, and ca3, of the eastern cape province south africa. |
2022-04-02 |
2023-08-13 |
cattle |
| Shu-Yi Huang, Zhong-Si-Wei Dong, Zhao-Hui Chen, Zhi-Wei Zeng, Wen-Qiao Zhao, Yan-Qing Guan, Chu-Hua L. Nano-MgO composites containing plasmid DNA to silence SNCA gene displays neuroprotective effects in Parkinson's rats induced by 6-hydroxydopamine. European journal of pharmacology. 2022-03-23. PMID:35318033. |
the overall length of dendritic and the total number of intersections were reduced by 6-oh da, accompanied by the decrease of the dendritic spine density in hippocampal ca1, ca3 and dg regions. |
2022-03-23 |
2023-08-13 |
rat |
| Sonja Fixemer, Corrado Ameli, Gaël Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Jean-Jacques Gérardy, Naguib Mechawar, Alexander Skupin, Michel Mittelbronn, David S Bouvie. Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer's disease and dementia with Lewy bodies. Acta neuropathologica communications. vol 10. issue 1. 2022-03-17. PMID:35296366. |
to this purpose, we employed an automated pipeline for analysis of 3d confocal microscopy images to assess ca1, ca3 and dg/ca4 subfields microglia responses in post-mortem hippocampal samples from late-onset ad (n = 10), dlb (n = 8) and age-matched control (ctl) (n = 11) individuals. |
2022-03-17 |
2023-08-13 |
Not clear |
| Sonja Fixemer, Corrado Ameli, Gaël Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Jean-Jacques Gérardy, Naguib Mechawar, Alexander Skupin, Michel Mittelbronn, David S Bouvie. Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer's disease and dementia with Lewy bodies. Acta neuropathologica communications. vol 10. issue 1. 2022-03-17. PMID:35296366. |
we identified two distinct microglia clusters enriched in disease conditions and particularly increased in ca1 and dg/ca4 of ad and ca3 of dlb. |
2022-03-17 |
2023-08-13 |
Not clear |
| Mojtaba Ehsanifar, Zeinab Yavari, Mehravar Rafat. Exposure to urban air pollution particulate matter: neurobehavioral alteration and hippocampal inflammation. Environmental science and pollution research international. 2022-03-03. PMID:35237914. |
the density of neurons in hippocampus ca1, ca3, and dentate gyrus (dg) regions decreased in deps mice. |
2022-03-03 |
2023-08-13 |
mouse |
| Zhu-Qing He, Peng-Fei Huan, Li Wang, Jian-Cheng H. Paeoniflorin ameliorates cognitive impairment in Parkinson's disease via JNK/p53 signaling. Metabolic brain disease. 2022-03-01. PMID:35230626. |
additionally, pf improved 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced neuronal injury by inhibiting apoptosis in hippocampal neurons of the ca1 and ca3, and upregulating psd-95 as well as syn protein levels. |
2022-03-01 |
2023-08-13 |
mouse |
| Hannah Twarkowksi, Victor Steininger, Min Jae Kim, Amar Saha. A dentate gyrus- CA3 inhibitory circuit promotes evolution of hippocampal-cortical ensembles during memory consolidation. eLife. vol 11. 2022-02-22. PMID:35191834. |
memories encoded in the dentate gyrus (dg) - ca3 circuit of the hippocampus are routed from ca1 to anterior cingulate cortex (acc) for consolidation. |
2022-02-22 |
2023-08-13 |
Not clear |
| Hannah Twarkowksi, Victor Steininger, Min Jae Kim, Amar Saha. A dentate gyrus- CA3 inhibitory circuit promotes evolution of hippocampal-cortical ensembles during memory consolidation. eLife. vol 11. 2022-02-22. PMID:35191834. |
although ca1 parvalbumin inhibitory neurons (pv ins) orchestrate hippocampal-cortical communication, we know less about ca3 pv ins or dg - ca3 principal neuron - in circuit mechanisms that contribute to evolution of hippocampal-cortical ensembles during memory consolidation. |
2022-02-22 |
2023-08-13 |
Not clear |
| Safa Ghaheri, Ali Niapour, Nona Sakhaie, Farshid Sadegzadeh, Hakimeh Saadat. Postnatal depletion of serotonin affects the morphology of neurons and the function of the hippocampus in male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-02-19. PMID:35181916. |
we found that critical developmental periods of serotonin depletion caused degeneration and swelling of neurons as well as significant neuronal loss in the hippocampal ca1, ca3, and dentate gyrus (dg) areas. |
2022-02-19 |
2023-08-13 |
rat |
| Ying Hao Yu, Yeou San Lim, Chen Yin Ou, Kai Chieh Chang, Arthur C Tsai, Fang Chih Chang, Andrew Chih Wei Huan. The Medial Prefrontal Cortex, Nucleus Accumbens, Basolateral Amygdala, and Hippocampus Regulate the Amelioration of Environmental Enrichment and Cue in Fear Behavior in the Animal Model of PTSD. Behavioural neurology. vol 2022. 2022-02-18. PMID:35178125. |
the present study addressed this issue and examined whether the medial prefrontal cortex (mpfc, including the cingulate cortex 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), the nucleus accumbens (nac), the basolateral amygdala (bla), and the hippocampus (e.g., ca1, ca3, and dentate gyrus (dg)) regulated the amelioration of the ee, cue, or the combination of ee and cue. |
2022-02-18 |
2023-08-13 |
Not clear |
| Ying Hao Yu, Yeou San Lim, Chen Yin Ou, Kai Chieh Chang, Arthur C Tsai, Fang Chih Chang, Andrew Chih Wei Huan. The Medial Prefrontal Cortex, Nucleus Accumbens, Basolateral Amygdala, and Hippocampus Regulate the Amelioration of Environmental Enrichment and Cue in Fear Behavior in the Animal Model of PTSD. Behavioural neurology. vol 2022. 2022-02-18. PMID:35178125. |
the mpfc (i.e., the cg1, prl, and il) and the hippocampus (i.e., the ca1, ca3, and dg) downregulated the c-fos expression in the suppression of the cue in fear behavior. |
2022-02-18 |
2023-08-13 |
Not clear |
| Marta Scarioni, Priya Gami-Patel, Carel F W Peeters, Florianne de Koning, Harro Seelaar, Merel O Mol, John C van Swieten, Annemieke J M Rozemuller, Jeroen J M Hoozemans, Yolande A L Pijnenburg, Anke A Dijkstr. Psychiatric symptoms of frontotemporal dementia and subcortical (co-)pathology burden: new insights. Brain : a journal of neurology. 2022-02-09. PMID:35136978. |
in subcortical regions, the presence of psychiatric symptoms showed positive correlations with increased hippocampal pathology burden: hallucinations with tdp-43 in the granular layer (r = 0.33), mania with tdp-43 in ca1 (r = 0.35), depression with tdp-43 in ca3 and with parahippocampal tau (r = 0.30 and r = 0.23), and delusions with ca3 tau (r = 0.26) and subicular amyloid-beta (r = 0.25). |
2022-02-09 |
2023-08-13 |
Not clear |
| Yuk-Hoi Yiu, Jill K Leutgeb, Christian Leibol. Directional Tuning of Phase Precession Properties in the Hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-02-03. PMID:35110389. |
here, using a previously published dataset that contains the spike activity of rat hippocampal place cells in the ca1, ca2 and ca3 subregions during free foraging of male long-evans rats in a 2d environment, we found that rate and spike timing codes are related. |
2022-02-03 |
2023-08-13 |
rat |