| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicolas G Bazan, Walter J Luki. Cyclooxygenase-2 and presenilin-1 gene expression induced by interleukin-1beta and amyloid beta 42 peptide is potentiated by hypoxia in primary human neural cells. The Journal of biological chemistry. vol 277. issue 33. 2002-09-20. PMID:12050157. |
this study provides data showing that the cox-2 and ps1 genes each transcribe rare, highly labile rna species that display early response gene behavior in human neural (hn) cells in primary culture, down-regulation during human neural development, and up-regulation in ad neocortex and hippocampal ca1. |
2002-09-20 |
2023-08-12 |
human |
| D W Cope, G Maccaferri, L F Márton, J D B Roberts, P M Cobden, P Somogy. Cholecystokinin-immunopositive basket and Schaffer collateral-associated interneurones target different domains of pyramidal cells in the CA1 area of the rat hippocampus. Neuroscience. vol 109. issue 1. 2002-04-11. PMID:11784700. |
therefore, at least two populations of pro-cholecystokinin-immunopositive interneurones, basket and schaffer collateral-associated cells, exist in the ca1 area of the hippocampus, and are probably homologous to cholecystokinin-immunopositive basket and double bouquet cells in the isocortex. |
2002-04-11 |
2023-08-12 |
rat |
| A C Hansson, A Cintra, N Belluardo, W Sommer, M Bhatnagar, M Bader, D Ganten, K Fux. Gluco- and mineralocorticoid receptor-mediated regulation of neurotrophic factor gene expression in the dorsal hippocampus and the neocortex of the rat. The European journal of neuroscience. vol 12. issue 8. 2000-10-19. PMID:10971634. |
we found that bfgf is regulated in ca2, ca3 and dentate gyrus by gr and mr together, and in ca1, ca4 and neocortex by gr alone. |
2000-10-19 |
2023-08-12 |
rat |
| A Takeuchi, M C Irizarry, K Duff, T C Saido, K Hsiao Ashe, M Hasegawa, D M Mann, B T Hyman, T Iwatsub. Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss. The American journal of pathology. vol 157. issue 1. 2000-08-08. PMID:10880403. |
to analyze the relationship between the deposition of amyloid beta peptides (abeta) and neuronal loss in transgenic models of alzheimer's disease (ad), we examined the frontal neocortex (fc) and ca1 portion of hippocampus (ca1) in psapp mice doubly expressing ad-associated mutant presenilin 1 (ps1) and swedish-type mutant beta amyloid precursor protein (appsw) by morphometry of abeta burden and neuronal counts. |
2000-08-08 |
2023-08-12 |
mouse |
| R A Armstrong, N J Cairns, P L Lanto. A quantitative study of the pathological lesions in the neocortex and hippocampus of twelve patients with corticobasal degeneration. Experimental neurology. vol 163. issue 2. 2000-07-17. PMID:10833308. |
in the hippocampus, the densities of bn were significantly lower than in the neocortex, and densities of tau+ neurons were greater in sectors ca1 and ca2, compared with ca3 and ca4. |
2000-07-17 |
2023-08-12 |
Not clear |
| R Herva, J Tyynelä, A Hirvasniemi, M Syrjäkallio-Ylitalo, M Halti. Northern epilepsy: a novel form of neuronal ceroid-lipofuscinosis. Brain pathology (Zurich, Switzerland). vol 10. issue 2. 2000-06-06. PMID:10764041. |
the granules were strongly stained by the luxol fast blue, periodic acid-schiff, and sudan black b methods in paraffin sections, and were immunoreactive for subunit c of the mitochondrial atp synthase and sphingolipid activator proteins a and d. the intraneuronal storage was highly selective: the third layer of the isocortex and the hippocampal ca2, ca3, and ca4 sectors were severely affected, while other layers of the isocortex, the ca1 sector, and the cerebellar cortex were only minimally involved. |
2000-06-06 |
2023-08-12 |
Not clear |
| A M Thomson, A Destexh. Dual intracellular recordings and computational models of slow inhibitory postsynaptic potentials in rat neocortical and hippocampal slices. Neuroscience. vol 92. issue 4. 1999-10-08. PMID:10426478. |
in most pairs tested in which the interneuron elicited a fast inhibitory postsynaptic potential in the pyramid, this gaba(a) receptor mediated inhibitory postsynaptic potential was entirely blocked by bicuculline or picrotoxin (3:3 in neocortex, 6:8 in ca1, all ca1 basket cells), even when high-frequency presynaptic spike trains were elicited. |
1999-10-08 |
2023-08-12 |
rat |
| K Horsburgh, D I Graham, J Stewart, J A Nicol. Influence of apolipoprotein E genotype on neuronal damage and apoE immunoreactivity in human hippocampus following global ischemia. Journal of neuropathology and experimental neurology. vol 58. issue 3. 1999-04-23. PMID:10197814. |
neuronal apoe immunoreactivity was significantly increased in all hippocampal sectors (ca1, ca2, ca3/ca4, dentate fascia) and in the neocortex of the global ischemia group compared with controls (p < 0.0001). |
1999-04-23 |
2023-08-12 |
human |
| J K Pinkstaff, J Detterich, G Lynch, C Gal. Integrin subunit gene expression is regionally differentiated in adult brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 5. 1999-04-20. PMID:10024342. |
general results and areas of notable labeling were as follows: alpha1-limited neuronal expression, neocortical layer v, hippocampal ca3; alpha3 and alpha5-diffuse neuronal and glial labeling, purkinje cells, hippocampal stratum pyramidale, locus coeruleus (alpha3); alpha4- discrete limbic regions, olfactory cortical layer ii, hippocampal ca2; alpha6-most prominently neuronal, neocortical subplate, endopiriform, subiculum; alpha7-discrete, all neocortical layers, hippocampal granule cells and ca3, cerebellar granule and purkinje cells, all efferent cranial nerve nuclei; alpha8-discrete neuronal, deep cortex, hippocampal ca1, basolateral amygdala, striatum; alphav-all cortical layers, striatum, purkinje cells; beta4-dentate gyrus granule cells; beta5-broadly distributed, neocortex, medial amygdala, cerebellar granule and purkinje cells, efferent cranial nerve nuclei; alpha2, beta2, and beta3-mrnas not detected. |
1999-04-20 |
2023-08-12 |
rat |
| J Shen, H S Kudrimoti, B L McNaughton, C A Barne. Reactivation of neuronal ensembles in hippocampal dentate gyrus during sleep after spatial experience. Journal of sleep research. vol 7 Suppl 1. 1998-10-22. PMID:9682188. |
patterns of neuronal activity recorded in ca1 of the hippocampus and in neocortex during waking-behavior, are reactivated during subsequent slow-wave sleep (sws). |
1998-10-22 |
2023-08-12 |
Not clear |
| H Ohishi, A Neki, N Mizun. Distribution of a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat and mouse: an immunohistochemical study with a monoclonal antibody. Neuroscience research. vol 30. issue 1. 1998-06-16. PMID:9572581. |
neuropil was intensely immunostained in the accessory olfactory bulb, bed nucleus of the accessory olfactory tract, neocortex, cingulate cortex, retrosplenial cortex, subicular and entorhinal cortices, stratum lacunosum-moleculare of ca1 and ca3, molecular layer of the dentate gyrus, periamygdaloid cortex, basolateral amygdaloid nucleus, bed nucleus of the anterior commissure, caudate-putamen, accumbens nucleus, thalamic reticular nucleus, anteroventral and paraventricular thalamic nuclei, granular layer of the cerebellar cortex, anterior and ventral tegmental nuclei, granular layer of the cochlear nucleus, and parvicellular part of the lateral reticular nucleus. |
1998-06-16 |
2023-08-12 |
mouse |
| C Largo, J M Ibarz, O Herrera. Effects of the gliotoxin fluorocitrate on spreading depression and glial membrane potential in rat brain in situ. Journal of neurophysiology. vol 78. issue 1. 1997-12-02. PMID:9242281. |
sd provoked in neocortex normally does not spread to the ca1, but during fc treatment it readily reached ca1 via entorhinal cortex. |
1997-12-02 |
2023-08-12 |
rat |
| M L Vizuete, J L Venero, E Traiffort, C Vargas, A Machado, J Can. Expression of 5-HT7 receptor mRNA in rat brain during postnatal development. Neuroscience letters. vol 227. issue 1. 1997-07-30. PMID:9178857. |
no quantitative developmental changes in the 5-ht7 gene expression was observed in neocortex, pyramidal layers of ca1 and ca2, dentate gyrus, most of thalamic nuclei, mammillary region, superior colliculus and central gray. |
1997-07-30 |
2023-08-12 |
rat |
| R K McNamara, R H Leno. Comparative distribution of myristoylated alanine-rich C kinase substrate (MARCKS) and F1/GAP-43 gene expression in the adult rat brain. The Journal of comparative neurology. vol 379. issue 1. 1997-05-22. PMID:9057112. |
marcks hybridization was most pronounced in the olfactory bulb, piriform cortex (layer ii), medial habenular nucleus, subregions of the amygdala, specific hypothalamic nuclei, hippocampal granule cells, neocortex, and cerebellar cortex, intermediate in the superior colliculus, hippocampal ca1, and certain brainstem nuclei including the locus coeruleus, and low-absent in regions of the caudate-putamen, geniculate, thalamic nuclei, lateral habenular nucleus, and hippocampal ca3 pyramidal and hilar neurons. |
1997-05-22 |
2023-08-12 |
rat |
| J L Yau, T Olsson, R G Morris, J Noble, J R Seck. Decreased NGFI-A gene expression in the hippocampus of cognitively impaired aged rats. Brain research. Molecular brain research. vol 42. issue 2. 1997-04-16. PMID:9013794. |
ngfi-a mrna expression decreased with age in ca1, ca2 and neocortex. |
1997-04-16 |
2023-08-12 |
rat |
| B S Rothberg, B E Hunter, D W Walker, J F Anderson, K J Anderso. Long-term effects of chronic ethanol on muscarinic receptor binding in rat brain. Alcoholism, clinical and experimental research. vol 20. issue 9. 1997-03-12. PMID:8986212. |
maximal binding of the radiolabeled machr antagonist quinuclidinyl benzilate ([3h]qnb) was not reduced in hippocampal area ca1, dentate gyrus, neocortex, striatum, or thalamus, suggesting that cet results in no significant machr loss in these regions. |
1997-03-12 |
2023-08-12 |
rat |
| M R Pelletier, J J Hablit. Tetraethylammonium-induced synaptic plasticity in rat neocortex. Cerebral cortex (New York, N.Y. : 1991). vol 6. issue 6. 1997-03-11. PMID:8922333. |
we investigated whether brief application of the potassium channel blocker tetraethylammonium (tea), which induces a novel form of synaptic plasticity in the ca1 region of the hippocampus referred to as ltpk, evokes similar responses in neocortex. |
1997-03-11 |
2023-08-12 |
rat |
| Z Kokaia, H Nawa, H Uchino, E Elmér, M Kokaia, J Carnahan, M L Smith, B K Siesjö, O Lindval. Regional brain-derived neurotrophic factor mRNA and protein levels following transient forebrain ischemia in the rat. Brain research. Molecular brain research. vol 38. issue 1. 1997-02-20. PMID:8737677. |
in ca1 and parietal cortex, bdnf protein decreased to 73-75% of control at 24 h. in contrast, bdnf mrna expression in dentate granule cells and ca3 pyramidal layer was transiently elevated to 287 and 293% of control, respectively, at 2 h, whereas no change was detected in ca1 or neocortex. |
1997-02-20 |
2023-08-12 |
rat |
| S A Neeper, F Gómez-Pinilla, J Choi, C W Cotma. Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain research. vol 726. issue 1-2. 1997-02-13. PMID:8836544. |
significant elevations in bdnf mrna were localized in ammon's horn areas 1 (ca1) and 4 (ca4) of the hippocampus, and layers ii-iii of the caudal neocortex and retrosplenial cortex. |
1997-02-13 |
2023-08-12 |
rat |
| J W Shar. PCP and ketamine inhibit non-NMDA glutamate receptor mediated hsp70 induction. Brain research. vol 728. issue 2. 1997-01-15. PMID:8864485. |
both diminished quisqualate and ampa hsp70 induction in the ca1, ca2, ca3 areas of the hippocampus, in the polymorph area of the dentate gyrus, and in the parietal neocortex. |
1997-01-15 |
2023-08-12 |
Not clear |