| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Caron Dean, Cecilia J Hillard, Jeanne L Seagard, Francis A Hopp, Quinn H Hoga. Upregulation of fatty acid amide hydrolase in the dorsal periaqueductal gray is associated with neuropathic pain and reduced heart rate in rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 312. issue 4. 2017-06-27. PMID:28148494. |
pain itself acts as a stressor, initiating autonomic and sensory effects through the dorsal periaqueductal gray (dpag) to induce both sympathoexcitation and analgesia, which prior studies have shown to be affected by endocannabinoid signaling. |
2017-06-27 |
2023-08-13 |
rat |
| Caron Dean, Cecilia J Hillard, Jeanne L Seagard, Francis A Hopp, Quinn H Hoga. Components of the cannabinoid system in the dorsal periaqueductal gray are related to resting heart rate. American journal of physiology. Regulatory, integrative and comparative physiology. vol 311. issue 2. 2017-06-26. PMID:27280429. |
the present study was undertaken to examine whether variations in endocannabinoid signaling in the dorsal periaqueductal gray (dpag) are associated with baseline autonomic nerve activity, heart rate, and blood pressure. |
2017-06-26 |
2023-08-13 |
rat |
| D L Uliana, S C Hott, S F Lisboa, L B M Resste. Dorsolateral periaqueductal gray matter CB1 and TRPV1 receptors exert opposite modulation on expression of contextual fear conditioning. Neuropharmacology. vol 103. 2016-12-13. PMID:26724373. |
cannabinoid type 1 (cb1) and transient potential vanilloid type 1 (trpv1) receptors in the dorsolateral periaqueductal gray (dlpag) matter are involved in the modulation of conditioned response. |
2016-12-13 |
2023-08-13 |
rat |
| P H Gobira, A F Almeida-Santos, F S Guimaraes, F A Moreira, D C Aguia. Role of the endocannabinoid 2-arachidonoylglycerol in aversive responses mediated by the dorsolateral periaqueductal grey. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 1. 2016-10-27. PMID:26628106. |
role of the endocannabinoid 2-arachidonoylglycerol in aversive responses mediated by the dorsolateral periaqueductal grey. |
2016-10-27 |
2023-08-13 |
Not clear |
| P H Gobira, A F Almeida-Santos, F S Guimaraes, F A Moreira, D C Aguia. Role of the endocannabinoid 2-arachidonoylglycerol in aversive responses mediated by the dorsolateral periaqueductal grey. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 1. 2016-10-27. PMID:26628106. |
this endocannabinoid and its hydrolyzing enzyme, monoacylglycerol lipase (magl), are present in encephalic regions related to psychiatric disorders, including the midbrain dorsolateral periaqueductal grey (dlpag). |
2016-10-27 |
2023-08-13 |
Not clear |
| Luigia Cristino, Livio Luongo, Roberta Imperatore, Serena Boccella, Thorsten Becker, Giovanna Morello, Fabiana Piscitelli, Giuseppe Busetto, Sabatino Maione, Vincenzo Di Marz. Orexin-A and Endocannabinoid Activation of the Descending Antinociceptive Pathway Underlies Altered Pain Perception in Leptin Signaling Deficiency. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 2. 2016-09-20. PMID:26081302. |
we show that leptin deficiency in ob/ob mice, or leptin insensitivity in the arcuate nucleus of the hypothalamus in mice with high-fat diet (hfd)-induced obesity, are accompanied by elevated orexin-a (ox-a) levels and orexin receptor-1 (ox1-r)-dependent elevation of the levels of the endocannabinoid, 2-arachidonoylglycerol (2-ag), in the ventrolateral periaqueductal gray (vlpag). |
2016-09-20 |
2023-08-13 |
mouse |
| Louise Corcoran, Michelle Roche, David P Fin. The Role of the Brain's Endocannabinoid System in Pain and Its Modulation by Stress. International review of neurobiology. vol 125. 2016-09-14. PMID:26638768. |
we provide a comprehensive evaluation of the role of the endocannabinoid system supraspinally, and particularly in the rostral ventromedial medulla, periaqueductal gray, amygdala, and prefrontal cortex, in pain, stress-induced analgesia, and stress-induced hyperalgesia. |
2016-09-14 |
2023-08-13 |
Not clear |
| Priscila A Batista, Manoela V Fogaça, Francisco S Guimarãe. The endocannabinoid, endovanilloid and nitrergic systems could interact in the rat dorsolateral periaqueductal gray matter to control anxiety-like behaviors. Behavioural brain research. vol 293. 2016-06-02. PMID:26187694. |
the endocannabinoid, endovanilloid and nitrergic systems could interact in the rat dorsolateral periaqueductal gray matter to control anxiety-like behaviors. |
2016-06-02 |
2023-08-13 |
rat |
| Priscila A Batista, Manoela V Fogaça, Francisco S Guimarãe. The endocannabinoid, endovanilloid and nitrergic systems could interact in the rat dorsolateral periaqueductal gray matter to control anxiety-like behaviors. Behavioural brain research. vol 293. 2016-06-02. PMID:26187694. |
low doses of the endocannabinoid anandamide (aea) injected into the dorsolateral periaqueductal gray matter (dlpag) induce anxiolytic-like effects via cb1 receptors activation. |
2016-06-02 |
2023-08-13 |
rat |
| Luara A Batista, Juliana R Bastos, Fabricio A Moreir. Role of endocannabinoid signalling in the dorsolateral periaqueductal grey in the modulation of distinct panic-like responses. Journal of psychopharmacology (Oxford, England). vol 29. issue 3. 2015-12-01. PMID:25601395. |
since the cannabinoid cb1 receptor modulates various types of aversive responses, this study tested the hypothesis that enhancement of endocannabinoid signalling in the dorsolateral periaqueductal grey inhibits panic-like reactions in rats. |
2015-12-01 |
2023-08-13 |
rat |
| Thércia G Viana, Sara C Hott, Leonardo B Resstel, Daniele C Aguiar, Fabrício A Moreir. Anti-aversive role of the endocannabinoid system in the periaqueductal gray stimulation model of panic attacks in rats. Psychopharmacology. vol 232. issue 9. 2015-11-20. PMID:25388290. |
anti-aversive role of the endocannabinoid system in the periaqueductal gray stimulation model of panic attacks in rats. |
2015-11-20 |
2023-08-13 |
rat |
| Thércia G Viana, Sara C Hott, Leonardo B Resstel, Daniele C Aguiar, Fabrício A Moreir. Anti-aversive role of the endocannabinoid system in the periaqueductal gray stimulation model of panic attacks in rats. Psychopharmacology. vol 232. issue 9. 2015-11-20. PMID:25388290. |
direct activation of the cannabinoid cb1 receptor in the dorsolateral periaqueductal gray (dlpag) inhibits anxiety- and panic-related behaviours in experimental animals. |
2015-11-20 |
2023-08-13 |
rat |
| A R Wilson-Poe, B K Lau, C W Vaugha. Repeated morphine treatment alters cannabinoid modulation of GABAergic synaptic transmission within the rat periaqueductal grey. British journal of pharmacology. vol 172. issue 2. 2015-09-10. PMID:24916363. |
repeated morphine treatment alters cannabinoid modulation of gabaergic synaptic transmission within the rat periaqueductal grey. |
2015-09-10 |
2023-08-13 |
rat |
| A R Wilson-Poe, B K Lau, C W Vaugha. Repeated morphine treatment alters cannabinoid modulation of GABAergic synaptic transmission within the rat periaqueductal grey. British journal of pharmacology. vol 172. issue 2. 2015-09-10. PMID:24916363. |
cannabinoids and opioids produce antinociception by modulating gabaergic synaptic transmission in a descending analgesic pathway from the midbrain periaqueductal grey (pag). |
2015-09-10 |
2023-08-13 |
rat |
| Benjamin K Lau, Geoffrey M Drew, Vanessa A Mitchell, Christopher W Vaugha. Endocannabinoid modulation by FAAH and monoacylglycerol lipase within the analgesic circuitry of the periaqueductal grey. British journal of pharmacology. vol 171. issue 23. 2015-08-14. PMID:25041240. |
endocannabinoid modulation by faah and monoacylglycerol lipase within the analgesic circuitry of the periaqueductal grey. |
2015-08-14 |
2023-08-13 |
Not clear |
| Benjamin K Lau, Geoffrey M Drew, Vanessa A Mitchell, Christopher W Vaugha. Endocannabinoid modulation by FAAH and monoacylglycerol lipase within the analgesic circuitry of the periaqueductal grey. British journal of pharmacology. vol 171. issue 23. 2015-08-14. PMID:25041240. |
endogenous cannabinoids (endocannabinoids) in the periaqueductal grey (pag) play a vital role in mediating stress-induced analgesia. |
2015-08-14 |
2023-08-13 |
Not clear |
| S F Lisboa, L H A Camargo, A C Magesto, L B M Resstel, F S Guimarãe. Cannabinoid modulation of predator fear: involvement of the dorsolateral periaqueductal gray. The international journal of neuropsychopharmacology. vol 17. issue 8. 2015-04-14. PMID:24438603. |
cannabinoid modulation of predator fear: involvement of the dorsolateral periaqueductal gray. |
2015-04-14 |
2023-08-12 |
rat |
| Lih-Chu Chiou, Sherry Shu-Jung Hu, Yu-Cheng H. Targeting the cannabinoid system for pain relief? Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists. vol 51. issue 4. 2015-04-13. PMID:24529672. |
in addition to the antinociceptive properties of exogenous cannabinoids and endocannabinoids, involving their biosynthesis and degradation processes, we also review recent studies that revealed a novel analgesic mechanism, involving 2-ag in the periaqueductal gray (pag), a midbrain region for initiating descending pain inhibition. |
2015-04-13 |
2023-08-12 |
Not clear |
| James J Burston, Stephen G Woodham. Endocannabinoid system and pain: an introduction. The Proceedings of the Nutrition Society. vol 73. issue 1. 2014-09-24. PMID:24148358. |
cannabinoid receptors and ligands are found at almost every level of the pain pathway from peripheral sites, such as peripheral nerves and immune cells, to central integration sites such as the spinal cord, and higher brain regions such as the periaqueductal grey and the rostral ventrolateral medulla associated with descending control of pain. |
2014-09-24 |
2023-08-12 |
Not clear |
| S F Lisboa, A C Magesto, J C Aguiar, L B M Resstel, F S Guimarãe. Complex interaction between anandamide and the nitrergic system in the dorsolateral periaqueductal gray to modulate anxiety-like behavior in rats. Neuropharmacology. vol 75. 2014-08-19. PMID:23899460. |
stimulation of cannabinoid cb1 receptors or inhibition of nitric oxide synthase (nos) in the dorsolateral periaqueductal gray (dlpag) decreases anxiety-like behavior. |
2014-08-19 |
2023-08-12 |
rat |