| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adrianne R Wilson, Lauren Maher, Michael M Morga. Repeated cannabinoid injections into the rat periaqueductal gray enhance subsequent morphine antinociception. Neuropharmacology. vol 55. issue 7. 2009-01-26. PMID:18723035. |
cannabinoids and opiates inhibit pain, in part, by activating the periaqueductal gray (pag). |
2009-01-26 |
2023-08-12 |
rat |
| L B M Resstel, S F Lisboa, D C Aguiar, F M A Corrêa, F S Guimarãe. Activation of CB1 cannabinoid receptors in the dorsolateral periaqueductal gray reduces the expression of contextual fear conditioning in rats. Psychopharmacology. vol 198. issue 3. 2008-11-17. PMID:18446325. |
activation of cb1 cannabinoid receptors in the dorsolateral periaqueductal gray reduces the expression of contextual fear conditioning in rats. |
2008-11-17 |
2023-08-12 |
rat |
| Sabrina F Lisboa, Leonardo B M Resstel, Daniele C Aguiar, Francisco S Guimarãe. Activation of cannabinoid CB1 receptors in the dorsolateral periaqueductal gray induces anxiolytic effects in rats submitted to the Vogel conflict test. European journal of pharmacology. vol 593. issue 1-3. 2008-11-12. PMID:18691568. |
activation of cannabinoid cb1 receptors in the dorsolateral periaqueductal gray induces anxiolytic effects in rats submitted to the vogel conflict test. |
2008-11-12 |
2023-08-12 |
rat |
| Sabrina F Lisboa, Leonardo B M Resstel, Daniele C Aguiar, Francisco S Guimarãe. Activation of cannabinoid CB1 receptors in the dorsolateral periaqueductal gray induces anxiolytic effects in rats submitted to the Vogel conflict test. European journal of pharmacology. vol 593. issue 1-3. 2008-11-12. PMID:18691568. |
activation of cannabinoid cb(1) receptors in the dorsolateral periaqueductal gray induces anxiolytic-like effects in the elevated plus maze. |
2008-11-12 |
2023-08-12 |
rat |
| Sabrina F Lisboa, Leonardo B M Resstel, Daniele C Aguiar, Francisco S Guimarãe. Activation of cannabinoid CB1 receptors in the dorsolateral periaqueductal gray induces anxiolytic effects in rats submitted to the Vogel conflict test. European journal of pharmacology. vol 593. issue 1-3. 2008-11-12. PMID:18691568. |
the results give further support to the proposal that facilitation of cb(1) receptor-mediated endocannabinoid neurotransmission in the dorsolateral periaqueductal gray modulates defensive responses. |
2008-11-12 |
2023-08-12 |
rat |
| Geoffrey M Drew, Vanessa A Mitchell, Christopher W Vaugha. Glutamate spillover modulates GABAergic synaptic transmission in the rat midbrain periaqueductal grey via metabotropic glutamate receptors and endocannabinoid signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 4. 2008-02-14. PMID:18216189. |
glutamate spillover modulates gabaergic synaptic transmission in the rat midbrain periaqueductal grey via metabotropic glutamate receptors and endocannabinoid signaling. |
2008-02-14 |
2023-08-12 |
rat |
| Paul A Smith, Dana E Selley, Laura J Sim-Selley, Sandra P Welc. Low dose combination of morphine and delta9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors. European journal of pharmacology. vol 571. issue 2-3. 2007-10-25. PMID:17603035. |
morphine and delta9-tetrahydrocannabinol (thc) produce antinociception via mu opioid and cannabinoid cb1 receptors, respectively, located in central nervous system (cns) regions including periaqueductal gray and spinal cord. |
2007-10-25 |
2023-08-12 |
rat |
| Paul A Smith, Dana E Selley, Laura J Sim-Selley, Sandra P Welc. Low dose combination of morphine and delta9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors. European journal of pharmacology. vol 571. issue 2-3. 2007-10-25. PMID:17603035. |
administration of thc attenuated cannabinoid cb1 receptor-stimulated g-protein activity in both periaqueductal gray and spinal cord, and administration of morphine decreased mu opioid receptor-stimulated [35s]gtpgammas binding in spinal cord or periaqueductal gray, depending on route of administration. |
2007-10-25 |
2023-08-12 |
rat |
| Fabrício Araújo Moreira, Daniele Cristina Aguiar, Francisco Silveira Guimarãe. Anxiolytic-like effect of cannabinoids injected into the rat dorsolateral periaqueductal gray. Neuropharmacology. vol 52. issue 3. 2007-05-01. PMID:17156799. |
anxiolytic-like effect of cannabinoids injected into the rat dorsolateral periaqueductal gray. |
2007-05-01 |
2023-08-12 |
rat |
| L Cristino, L de Petrocellis, G Pryce, D Baker, V Guglielmotti, V Di Marz. Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain. Neuroscience. vol 139. issue 4. 2006-07-26. PMID:16603318. |
cannabinoid type 1/transient receptor potential vanilloid type 1 expression was observed in the hippocampus, basal ganglia, thalamus, hypothalamus, cerebral peduncle, pontine nuclei, periaqueductal gray matter, cerebellar cortex and dentate cerebellar nucleus. |
2006-07-26 |
2023-08-12 |
mouse |
| L Cristino, L de Petrocellis, G Pryce, D Baker, V Guglielmotti, V Di Marz. Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain. Neuroscience. vol 139. issue 4. 2006-07-26. PMID:16603318. |
cannabinoid type 1 and transient receptor potential vanilloid type 1 immunoreactivity was also detected in: a) the globus pallidus and substantia nigra, in which some intensely transient receptor potential vanilloid type 1 immunopositive cell bodies were found in dense and fine cannabinoid type 1/transient receptor potential vanilloid type 1 positive and cannabinoid type 1 positive nerve fiber meshworks, respectively; b) the cytoplasm of thalamic and hypothalamic neurons; and c) some neurons of the ventral periaqueductal gray. |
2006-07-26 |
2023-08-12 |
mouse |
| Richard L Suplita, Tannia Gutierrez, Darren Fegley, Daniele Piomelli, Andrea G Hohman. Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia. Neuropharmacology. vol 50. issue 3. 2006-05-24. PMID:16316669. |
non-opioid sia, induced by a 3-min continuous foot shock, is characterized by the mobilization of two endocannabinoid lipids--2-arachidonoylglycerol (2-ag) and anandamide--in the midbrain periaqueductal gray (pag). |
2006-05-24 |
2023-08-12 |
rat |
| Sabatino Maione, Tiziana Bisogno, Vito de Novellis, Enza Palazzo, Luigia Cristino, Marta Valenti, Stefania Petrosino, Vittorio Guglielmotti, Francesco Rossi, Vincenzo Di Marz. Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors. The Journal of pharmacology and experimental therapeutics. vol 316. issue 3. 2006-04-13. PMID:16284279. |
elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors. |
2006-04-13 |
2023-08-12 |
rat |
| Richard L Suplita, Jesse N Farthing, Tannia Gutierrez, Andrea G Hohman. Inhibition of fatty-acid amide hydrolase enhances cannabinoid stress-induced analgesia: sites of action in the dorsolateral periaqueductal gray and rostral ventromedial medulla. Neuropharmacology. vol 49. issue 8. 2006-01-17. PMID:16129456. |
inhibition of fatty-acid amide hydrolase enhances cannabinoid stress-induced analgesia: sites of action in the dorsolateral periaqueductal gray and rostral ventromedial medulla. |
2006-01-17 |
2023-08-12 |
Not clear |
| Richard L Suplita, Jesse N Farthing, Tannia Gutierrez, Andrea G Hohman. Inhibition of fatty-acid amide hydrolase enhances cannabinoid stress-induced analgesia: sites of action in the dorsolateral periaqueductal gray and rostral ventromedial medulla. Neuropharmacology. vol 49. issue 8. 2006-01-17. PMID:16129456. |
the present studies were conducted to examine the role of cannabinoid cb(1) receptors in the brainstem rostral ventromedial medulla (rvm) and midbrain dorsolateral periaqueductal gray (pag) in cannabinoid stress-induced analgesia (sia). |
2006-01-17 |
2023-08-12 |
Not clear |
| V de Novellis, L Mariani, E Palazzo, D Vita, I Marabese, M Scafuro, F Rossi, S Maion. Periaqueductal grey CB1 cannabinoid and metabotropic glutamate subtype 5 receptors modulate changes in rostral ventromedial medulla neuronal activities induced by subcutaneous formalin in the rat. Neuroscience. vol 134. issue 1. 2005-12-02. PMID:15953687. |
periaqueductal grey cb1 cannabinoid and metabotropic glutamate subtype 5 receptors modulate changes in rostral ventromedial medulla neuronal activities induced by subcutaneous formalin in the rat. |
2005-12-02 |
2023-08-12 |
rat |
| V de Novellis, L Mariani, E Palazzo, D Vita, I Marabese, M Scafuro, F Rossi, S Maion. Periaqueductal grey CB1 cannabinoid and metabotropic glutamate subtype 5 receptors modulate changes in rostral ventromedial medulla neuronal activities induced by subcutaneous formalin in the rat. Neuroscience. vol 134. issue 1. 2005-12-02. PMID:15953687. |
this study was undertaken to analyze the involvement of periaqueductal gray (pag) cannabinoid or group i metabotropic glutamate receptors in the formalin-induced changes on the rostral ventromedial medulla (rvm) on- and off-cells activities. |
2005-12-02 |
2023-08-12 |
rat |
| Andrea G Hohmann, Richard L Suplita, Nathan M Bolton, Mark H Neely, Darren Fegley, Regina Mangieri, Jocelyn F Krey, J Michael Walker, Philip V Holmes, Jonathon D Crystal, Andrea Duranti, Andrea Tontini, Marco Mor, Giorgio Tarzia, Daniele Piomell. An endocannabinoid mechanism for stress-induced analgesia. Nature. vol 435. issue 7045. 2005-07-14. PMID:15973410. |
blockade of cannabinoid cb(1) receptors in the periaqueductal grey matter of the midbrain prevents non-opioid stress-induced analgesia. |
2005-07-14 |
2023-08-12 |
Not clear |
| D P Finn, M D Jhaveri, S R G Beckett, C H Roe, D A Kendall, C A Marsden, V Chapma. Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats. Neuropharmacology. vol 45. issue 5. 2003-12-19. PMID:12941373. |
we investigated the hypothesis that the midbrain periaqueductal grey (pag) is a common substrate mediating the anti-nociceptive and potential aversive effects of cannabinoids. |
2003-12-19 |
2023-08-12 |
rat |
| C W Vaughan, M Connor, E E Bagley, M J Christi. Actions of cannabinoids on membrane properties and synaptic transmission in rat periaqueductal gray neurons in vitro. Molecular pharmacology. vol 57. issue 2. 2000-03-02. PMID:10648638. |
actions of cannabinoids on membrane properties and synaptic transmission in rat periaqueductal gray neurons in vitro. |
2000-03-02 |
2023-08-12 |
rat |