| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew J Haney, Yuling Zhao, James Fay, Hwang Duhyeong, Mengzhe Wang, Hui Wang, Zibo Li, Yueh Z Lee, Mohan K Karuppan, Nazira El-Hage, Alexander V Kabanov, Elena V Batrakov. Genetically modified macrophages accomplish targeted gene delivery to the inflamed brain in transgenic Parkin Q311X(A) mice: importance of administration routes. Scientific reports. vol 10. issue 1. 2020-12-21. PMID:32678262. |
gdnf-transfected macrophages administered through intrathecal route provided significant increases of gdnf levels in different brain sub-regions, including midbrain, cerebellum, frontal cortex, and pons. |
2020-12-21 |
2023-08-13 |
mouse |
| James Auta, Eleonora Gatta, John M Davis, Huaibo Zhang, Subhash C Pandey, Alessandro Guidott. Essential role for neuronal nitric oxide synthase in acute ethanol-induced motor impairment. Nitric oxide : biology and chemistry. vol 100-101. 2020-12-15. PMID:32278831. |
here, we investigated the dose-dependent effects of acute ethanol treatment on motor impairment using the rotarod behavioral paradigm and the alterations of nnos mrna expression in cerebellum, frontal cortex (fc), hippocampus and striatum. |
2020-12-15 |
2023-08-13 |
Not clear |
| Wen Hu, Feng Wu, Yanchong Zhang, Cheng-Xin Gong, Khalid Iqbal, Fei Li. Expression of Tau Pathology-Related Proteins in Different Brain Regions: A Molecular Basis of Tau Pathogenesis. Frontiers in aging neuroscience. vol 9. 2020-10-01. PMID:29021756. |
we found that tau was hyperphosphorylated at multiple sites in the frontal cortex (fc), but not in the cerebellum, from ad brain. |
2020-10-01 |
2023-08-13 |
human |
| Silvia Seghezzi, Eleonora Zirone, Eraldo Paulesu, Laura Zapparol. The Brain in (Willed) Action: A Meta-Analytical Comparison of Imaging Studies on Motor Intentionality and Sense of Agency. Frontiers in psychology. vol 10. 2020-10-01. PMID:31031676. |
beside a shared brain network involving the meso-frontal and prefrontal regions, the middle insula and subcortical structures, we found that motor intention and the sense of agency are functionally underpinned by separable sets of brain regions: an "intentionality network," involving the rostral area of the mesial frontal cortex (middle cingulum and pre-supplementary motor area), the anterior insula and the parietal lobules, and a "self-agency network," which involves the posterior areas of the mesial frontal cortex (the sma proper), the posterior insula, the occipital lobe and the cerebellum. |
2020-10-01 |
2023-08-13 |
Not clear |
| Xianrui Li, Meng Zhang, Kun Li, Feng Zou, Yufeng Wang, Xin Wu, Hongxing Zhan. The Altered Somatic Brain Network in State Anxiety. Frontiers in psychiatry. vol 10. 2020-10-01. PMID:31312147. |
furthermore, we found that state anxiety was positively correlated with the connections between the postcentral gyrus and the left cerebellum gyrus, whereas state anxiety was negatively correlated with the connectivity between the postcentral gyrus and brain regions including the left inferior frontal cortex and left medial superior frontal cortex. |
2020-10-01 |
2023-08-13 |
Not clear |
| Olena Lykhmus, Larysa P Voytenko, Katrin S Lips, Ivonne Bergen, Gabriela Krasteva-Christ, Douglas E Vetter, Wolfgang Kummer, Maryna Sko. Nicotinic Acetylcholine Receptor α9 and α10 Subunits Are Expressed in the Brain of Mice. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28955208. |
the α9 and α10 rna transcripts were found in medulla oblongata (mo), cerebellum, midbrain (mb), thalamus and putamen (tp), somatosensory cortex (sc), frontal cortex (fc) and hippocampus. |
2020-09-30 |
2023-08-13 |
mouse |
| I Smaga, D Gawlinski, J Brodowicz, M Fili. Brain region-dependent changes in the expression of endocannabinoid-metabolizing enzymes in rats following antidepressant drugs. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 70. issue 5. 2020-06-15. PMID:31889042. |
after imi treatment a reduction was noted in the expression of faah protein in the dorsal striatum, magl in the frontal cortex and daglα in the cerebellum. |
2020-06-15 |
2023-08-13 |
rat |
| L Holper, D Ben-Shachar, J J Man. Multivariate meta-analyses of mitochondrial complex I and IV in major depressive disorder, bipolar disorder, schizophrenia, Alzheimer disease, and Parkinson disease. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 5. 2019-12-18. PMID:29855563. |
separate meta-analyses of mood disorder studies, mdd and bd, revealed moderate effect sizes for similar abnormality patterns in the expression of complex i with sz in frontal cortex, cerebellum and striatum, whereas evidence for complex iv alterations was low. |
2019-12-18 |
2023-08-13 |
Not clear |
| V Zaman, Z Li, L Middaugh, S Ramamoorthy, B Rohrer, M E Nelson, A C Tomac, B J Hoffer, G A Gerhardt, A Ch Granhol. The Noradrenergic System of Aged GDNF Heterozygous Mice. Cell transplantation. vol 12. issue 3. 2019-11-20. PMID:28853928. |
tyrosine hydroxylase (th) immunostaining demonstrated morphological alterations of lc-ne cell bodies and abnormal th-positive fibers in the hippocampus, cerebellum, and frontal cortex of gdnf+/- mice. |
2019-11-20 |
2023-08-13 |
mouse |
| Mohamed A Sherif, Jose A Cortes-Briones, Mohini Ranganathan, Patrick D Skosni. Cannabinoid-glutamate interactions and neural oscillations: implications for psychosis. The European journal of neuroscience. vol 48. issue 8. 2019-11-14. PMID:29247465. |
indeed, in several brain regions implicated in the putative neural circuitry of sz (e.g., hippocampus, frontal cortex, cerebellum), cannabinoid receptor type 1 (cb1rs) and glutamate n-methyl-d-aspartate receptors (nmdars) have direct and indirect interactions. |
2019-11-14 |
2023-08-13 |
Not clear |
| Prasunpriya Nayak, Shiv Bhushan Sharma, N V S Chowdar. Alpha-Tocopherol Supplementation Restricts Aluminium- and Ethanol-Induced Oxidative Damage in Rat Brain but Fails to Protect Against Neurobehavioral Damage. Journal of dietary supplements. vol 16. issue 3. 2019-08-12. PMID:29621413. |
os parameters are tested in frontal cortex (fc), hippocampus (hc), and cerebellum (cl) of α-tocopherol-supplemented (5 iu/day) male wistar rats exposed to aluminium (10 mg al/kg/day; "al"), ethanol (0.6 g ethanol/kg/day; "et"), and both ("al-et") and vehicle-treated control ("c") for 4 weeks. |
2019-08-12 |
2023-08-13 |
rat |
| Pranav Vemula, Yu Jing, Hu Zhang, Jerry B Hunt, Leslie A Sandusky-Beltran, Daniel C Lee, Ping Li. Altered brain arginine metabolism in a mouse model of tauopathy. Amino acids. vol 51. issue 3. 2019-07-24. PMID:30604097. |
using high-performance liquid chromatographic and mass spectrometric assays, the present study systematically determined the tissue concentrations of l-arginine and its nine downstream metabolites in the frontal cortex, hippocampus, parahippocampal region, striatum, thalamus, and cerebellum in male ps19 mice-bearing human tau p301s mutation at 4, 8, and 12-14 months of age. |
2019-07-24 |
2023-08-13 |
mouse |
| Margaret Quinn, Maureen McHugo, Kristan Armstrong, Neil Woodward, Jennifer Blackford, Stephan Hecker. Impact of substance use disorder on gray matter volume in schizophrenia. Psychiatry research. Neuroimaging. vol 280. 2019-07-09. PMID:30121336. |
relative to controls, patients with schizophrenia had reduced gray matter volume in the bilateral precentral gyrus, right medial frontal cortex, right visual cortex, right occipital pole, right thalamus, bilateral amygdala, and bilateral cerebellum regardless of substance use history. |
2019-07-09 |
2023-08-13 |
human |
| Shahram Saberi, Jennifer E Stauffer, Jie Jiang, Sandra Diaz Garcia, Amy E Taylor, Derek Schulte, Takuya Ohkubo, Cheyenne L Schloffman, Marcus Maldonado, Michael Baughn, Maria J Rodriguez, Don Pizzo, Don Cleveland, John Ravit. Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis. Acta neuropathologica. vol 135. issue 3. 2019-07-01. PMID:29196813. |
the c9orf72 protein itself was diffusely expressed in cytoplasm of large neurons and glia, and nearly 50% reduced, in both clinically related frontal cortex and unrelated occipital cortex, but not in cerebellum. |
2019-07-01 |
2023-08-13 |
Not clear |
| Camryn Harvie, Steven J Weissbart, Priyanka Kadam-Halani, Hengyi Rao, Lily A Ary. Brain activation during the voiding phase of micturition in healthy adults: A meta-analysis of neuroimaging studies. Clinical anatomy (New York, N.Y.). vol 32. issue 1. 2019-04-16. PMID:30069958. |
regions of the brain involved in executive control (frontal cortex), interoception (acc, insula), motor control (cerebellum, thalamus), and brainstem (pons) are involved in micturition. |
2019-04-16 |
2023-08-13 |
human |
| Marianna Manes, Mariana de Souza Aranha Garcia-Gomes, Thaísa Meira Sandini, Julia Zaccarelli-Magalhães, Jorge Camilo Florio, Sandra Regina Alexandre-Ribeiro, Danilo Wadt, Maria Martha Bernardi, Silvia Maria Gomes Massironi, Claudia Madalena Cabrera Mor. Behavioral and neurochemical characterization of the mlh mutant mice lacking otoconia. Behavioural brain research. vol 359. 2019-04-03. PMID:29913187. |
as well, the neurotransmitter levels in the cerebellum, striatum, frontal cortex, and hippocampus were measured. |
2019-04-03 |
2023-08-13 |
mouse |
| Marianna Manes, Mariana de Souza Aranha Garcia-Gomes, Thaísa Meira Sandini, Julia Zaccarelli-Magalhães, Jorge Camilo Florio, Sandra Regina Alexandre-Ribeiro, Danilo Wadt, Maria Martha Bernardi, Silvia Maria Gomes Massironi, Claudia Madalena Cabrera Mor. Behavioral and neurochemical characterization of the mlh mutant mice lacking otoconia. Behavioural brain research. vol 359. 2019-04-03. PMID:29913187. |
relative to balb/c mice, the mutant mlh mice showed 1) reduced locomotor and rearing behavior, increased auricular and touch reflexes, decreased motor coordination and increased micturition; 2) decreased responses in the t-maze and aversive wooden beam tests; 3) increased time of immobility in the tail suspension test; 4) no effects in the elevated plus maze or object recognition test; 5) an inability to swim; and 6) reduced turnover of dopaminergic system in the cerebellum, striatum, and frontal cortex. |
2019-04-03 |
2023-08-13 |
mouse |
| Susmita Sil, Palsamy Periyasamy, Ming-Lei Guo, Shannon Callen, Shilpa Buc. Morphine-Mediated Brain Region-Specific Astrocytosis Involves the ER Stress-Autophagy Axis. Molecular neurobiology. vol 55. issue 8. 2019-02-26. PMID:29344928. |
in vivo validation demonstrated preferential activation of er stress/autophagy axis in the areas of the brain not associated with pain such as the basal ganglia, frontal cortex, occipital cortex, and the cerebellum of morphine-dependent rhesus macaques, and this correlated with increased astrocyte activation and neuroinflammation. |
2019-02-26 |
2023-08-13 |
human |
| Helge Leander B Jensen, Meryl S Lillenes, Alberto Rabano, Clara-Cecilie Günther, Tahira Riaz, Shewit T Kalayou, Ingun D Ulstein, Thomas Bøhmer, Tone Tønju. Expression of nucleotide excision repair in Alzheimer's disease is higher in brain tissue than in blood. Neuroscience letters. vol 672. 2019-02-18. PMID:29474873. |
further, lig3 mrna levels in the frontal cortex was higher in ad versus hc, while mrna levels of mpg and lig3 in entorhinal cortex and rpa1 in the cerebellum were lower in ad versus hc. |
2019-02-18 |
2023-08-13 |
Not clear |
| Katarina Krbot, Peter Hermann, Magdalena Krbot Skorić, Inga Zerr, Diego Sepulveda-Falla, Stefan Goebel, Jakob Matschke, Susanne Krasemann, Markus Glatze. Distinct microglia profile in Creutzfeldt-Jakob disease and Alzheimer's disease is independent of disease kinetics. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 38. issue 6. 2019-01-18. PMID:30318820. |
we immunostained the frontal cortex, basal ganglia and cerebellum in 16 patients with rpad and scjd using antibodies against markers of microglia and recruited monocytes (ionized calcium-binding adaptor molecule 1, human leukocyte antigen dpqr, cluster of differentiation 68), an antibody unique to brain-resident microglia (transmembrane protein 119 (tmem119)), in addition to antibodies against a marker of astrocytes (glial fibrillary acidic protein), amyloid-β (aβ) and pathological prion protein. |
2019-01-18 |
2023-08-13 |
human |