| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miranda C Staples, Airee Kim, Chitra D Mandya. Dendritic remodeling of hippocampal neurons is associated with altered NMDA receptor expression in alcohol dependent rats. Molecular and cellular neurosciences. vol 65. 2016-01-11. PMID:25769285. |
previous work from our lab utilizing a clinically relevant rodent model of alcohol consumption demonstrated that alcohol dependence (induced by chronic intermittent ethanol vapor exposure or cie) decreases proliferation and survival of neural stem cells in the hippocampal subgranular zone and hippocampal neurogenesis in the dentate gyrus, implicating this region of the cortex as particularly sensitive to the toxic effects of prolonged ethanol exposure. |
2016-01-11 |
2023-08-13 |
rat |
| Paul D Drew, Jennifer W Johnson, James C Douglas, Kevin D Phelan, Cynthia J M Kan. Pioglitazone blocks ethanol induction of microglial activation and immune responses in the hippocampus, cerebellum, and cerebral cortex in a mouse model of fetal alcohol spectrum disorders. Alcoholism, clinical and experimental research. vol 39. issue 3. 2015-11-27. PMID:25703036. |
pioglitazone blocks ethanol induction of microglial activation and immune responses in the hippocampus, cerebellum, and cerebral cortex in a mouse model of fetal alcohol spectrum disorders. |
2015-11-27 |
2023-08-13 |
mouse |
| Kyungjin Lee, Bumjung Kim, Heseung Hur, Khanita Suman Chinannai, Inhye Ham, Ho-Young Cho. Antihypertensive Effect of the GaMiSamHwangSaSimTang in Spontaneous Hypertensive Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-11-05. PMID:26539233. |
the present study was designed to evaluate the antihypertensive effect of gamisamhwangsasimtang (hvc1), a 30% ethanol extract of a mixture comprising pruni cortex, scutellariae radix, coptidis rhizoma, and rhei rhizoma, on spontaneous hypertensive rats (shrs). |
2015-11-05 |
2023-08-13 |
rat |
| Francisco Bruno Teixeira, Luana Nazaré da Silva Santana, Fernando Romualdo Bezerra, Sabrina De Carvalho, Enéas Andrade Fontes-Júnior, Rui Daniel Prediger, Maria Elena Crespo-López, Cristiane Socorro Ferraz Maia, Rafael Rodrigues Lim. Chronic ethanol exposure during adolescence in rats induces motor impairments and cerebral cortex damage associated with oxidative stress. PloS one. vol 9. issue 6. 2015-10-07. PMID:24967633. |
chronic ethanol exposure during adolescence in rats induces motor impairments and cerebral cortex damage associated with oxidative stress. |
2015-10-07 |
2023-08-13 |
rat |
| Francisco Bruno Teixeira, Luana Nazaré da Silva Santana, Fernando Romualdo Bezerra, Sabrina De Carvalho, Enéas Andrade Fontes-Júnior, Rui Daniel Prediger, Maria Elena Crespo-López, Cristiane Socorro Ferraz Maia, Rafael Rodrigues Lim. Chronic ethanol exposure during adolescence in rats induces motor impairments and cerebral cortex damage associated with oxidative stress. PloS one. vol 9. issue 6. 2015-10-07. PMID:24967633. |
in the current study, we evaluated motor performance and tissue alterations in the cerebral cortex of rats subjected to intermittent intoxication with ethanol from adolescence to adulthood. |
2015-10-07 |
2023-08-13 |
rat |
| Francisco Bruno Teixeira, Luana Nazaré da Silva Santana, Fernando Romualdo Bezerra, Sabrina De Carvalho, Enéas Andrade Fontes-Júnior, Rui Daniel Prediger, Maria Elena Crespo-López, Cristiane Socorro Ferraz Maia, Rafael Rodrigues Lim. Chronic ethanol exposure during adolescence in rats induces motor impairments and cerebral cortex damage associated with oxidative stress. PloS one. vol 9. issue 6. 2015-10-07. PMID:24967633. |
these findings indicate that continuous ethanol intoxication from adolescence to adulthood is able to provide neurobehavioral and neurodegenerative damage to cerebral cortex. |
2015-10-07 |
2023-08-13 |
rat |
| Ryota Shirai, Takuya Kunii, Akio Yoneyama, Takahito Ooizumi, Hiroko Maruyama, Thet Thet Lwin, Kazuyuki Hyodo, Tohoru Taked. Enhanced renal image contrast by ethanol fixation in phase-contrast X-ray computed tomography. Journal of synchrotron radiation. vol 21. issue Pt 4. 2015-09-30. PMID:24971977. |
the ethanol fixation technique enhances image contrast by approximately 2.7-3.2 times in the cortex and the outer stripe of the outer medulla; the effect of shrinkage and the physical effect of ethanol cause an increment of approximately 78% and 22%, respectively. |
2015-09-30 |
2023-08-13 |
Not clear |
| A Savarese, M E Zou, V Kharazia, R Maiya, A W Lase. Increased behavioral responses to ethanol in Lmo3 knockout mice. Genes, brain, and behavior. vol 13. issue 8. 2015-07-23. PMID:25176312. |
to explore where lmo3 may be acting in the brain to produce an ethanol phenotype, we also examined reporter gene (β-galactosidase) expression in heterozygous lmo3(z) mice and found strong expression in subcortical areas, particularly in those areas implicated in drug abuse, including the nucleus accumbens (acb), cortex, hippocampus and amygdala. |
2015-07-23 |
2023-08-13 |
mouse |
| Brandon M Fritz, Stephen L Boeh. Site-specific microinjection of Gaboxadol into the infralimbic cortex modulates ethanol intake in male C57BL/6J mice. Behavioural brain research. vol 273. 2015-05-11. PMID:25043731. |
site-specific microinjection of gaboxadol into the infralimbic cortex modulates ethanol intake in male c57bl/6j mice. |
2015-05-11 |
2023-08-13 |
mouse |
| Andrey Finegersh, Gregg E Homanic. Acute ethanol alters multiple histone modifications at model gene promoters in the cerebral cortex. Alcoholism, clinical and experimental research. vol 38. issue 7. 2015-04-14. PMID:24942484. |
acute ethanol alters multiple histone modifications at model gene promoters in the cerebral cortex. |
2015-04-14 |
2023-08-13 |
Not clear |
| Andrey Finegersh, Gregg E Homanic. Acute ethanol alters multiple histone modifications at model gene promoters in the cerebral cortex. Alcoholism, clinical and experimental research. vol 38. issue 7. 2015-04-14. PMID:24942484. |
ethanol (etoh) exposure alters gene expression in the cerebral cortex (ccx); however, mechanisms of etoh-induced gene regulation are not well understood. |
2015-04-14 |
2023-08-13 |
Not clear |
| Nuzhath Tajuddin, Kwan-Hoon Moon, S Alex Marshall, Kimberly Nixon, Edward J Neafsey, Hee-Yong Kim, Michael A Collin. Neuroinflammation and neurodegeneration in adult rat brain from binge ethanol exposure: abrogation by docosahexaenoic acid. PloS one. vol 9. issue 7. 2015-03-09. PMID:25029343. |
in adult male rats, repetitive ethanol intoxication (3 gavages/d for 4 d, ∼ 9 g/kg/d, achieving blood ethanol levels ∼ 375 mg/dl; "majchrowicz" model) significantly increased aqp4, ca+2-dependent pla2 giva (cpla2), phospho-cpla2 giva (p-cpla2), secretory pla2 giia (spla2) and parp-1 in regions incurring extensive neurodegeneration in this model--hippocampus, entorhinal cortex, and olfactory bulb--but not in two regions typically lacking neurodamage, frontal cortex and cerebellum. |
2015-03-09 |
2023-08-13 |
rat |
| Jason B Cook, Stephanie M Nelli, Mackenzie R Neighbors, Danielle H Morrow, Todd K O'Buckley, Antoniette M Maldonado-Devincci, A Leslie Morro. Ethanol alters local cellular levels of (3α,5α)-3-hydroxypregnan-20-one (3α,5α-THP) independent of the adrenals in subcortical brain regions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 8. 2015-02-12. PMID:24566803. |
in rats, ethanol activates the hypothalamic-pituitary-adrenal axis and elevates 3α,5α-thp in plasma, cerebral cortex, and hippocampus. |
2015-02-12 |
2023-08-12 |
rat |
| A G Karadayian, J Bustamante, A Czerniczyniec, R A Cutrera, S Lores-Arnai. Effect of melatonin on motor performance and brain cortex mitochondrial function during ethanol hangover. Neuroscience. vol 269. 2015-02-12. PMID:24713372. |
effect of melatonin on motor performance and brain cortex mitochondrial function during ethanol hangover. |
2015-02-12 |
2023-08-13 |
mouse |
| Caroline Lücke, Tonio Heidegger, Mirjam Röhner, Stefan W Toennes, Lucia Krivanekova, Florian Müller-Dahlhaus, Ulf Zieman. Deleterious effects of a low amount of ethanol on LTP-like plasticity in human cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 6. 2014-12-15. PMID:24385131. |
deleterious effects of a low amount of ethanol on ltp-like plasticity in human cortex. |
2014-12-15 |
2023-08-12 |
human |
| Gedeão Batista Oliveira, Enéas de Andrade Fontes, Sabrina de Carvalho, Josiane Batista da Silva, Luanna Melo Pereira Fernandes, Maria Cristina Souza Pereira Oliveira, Rui Daniel Prediger, Walace Gomes-Leal, Rafael Rodrigues Lima, Cristiane Socorro Ferraz Mai. Minocycline mitigates motor impairments and cortical neuronal loss induced by focal ischemia in rats chronically exposed to ethanol during adolescence. Brain research. vol 1561. 2014-12-08. PMID:24637259. |
minocycline reversed the observed motor impairments, microglial activation and pyramidal neuron loss in the motor cortex of ischemic rats even in those exposed to ethanol. |
2014-12-08 |
2023-08-12 |
rat |
| Jing Zhang, Li-Ting Yan, En-Lin Yuan, Hai-Xin Ding, Huo-Chun Ye, Zheng-Ke Zhang, Chao Yan, Ying-Qian Liu, Gang Fen. Antifungal activity of compounds extracted from Cortex Pseudolaricis against Colletotrichum gloeosporioides. Journal of agricultural and food chemistry. vol 62. issue 21. 2014-11-03. PMID:24820992. |
in order to find the natural antifungal agents against mango anthracnose, eight compounds, namely pseudolaric acid a (1), ethyl pseudolaric acid b (2), pseudolaric acid b (3), pseudolaric acid b-o-β-d-glucoside (4), piperonylic acid (5), propionic acid (6), 3-hydroxy-4-methoxybenzoic acid (7), and 4-(3-formyl-5-methoxyphenyl) butanoic acid (8) were isolated from the ethanol extracts of cortex pseudolaricis by bioassay-guided fractionation and evaluated for in vitro antifungal activity against colletotrichum gloeosporioides penz. |
2014-11-03 |
2023-08-13 |
Not clear |
| Ricardo Fontão de Pauli, Cássia Canha Coelhoso, Carolina Tesone-Coelho, Alessandra Linardi, Luiz Eugênio Mello, Dartiu Xavier Silveira, Jair Guilherme Santo. Differential patterns of expression of neuropeptide Y throughout abstinence in outbred Swiss mice classified as susceptible or resistant to ethanol-induced locomotor sensitization. Alcohol (Fayetteville, N.Y.). vol 48. issue 1. 2014-10-22. PMID:24406115. |
lastly, a decreased level of npy was found in the prelimbic cortex of the etoh_low mice at 5 days of abstinence, and this was reversed by ethanol challenge. |
2014-10-22 |
2023-08-12 |
mouse |
| A Pla, M Pascual, J Renau-Piqueras, C Guerr. TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain. Cell death & disease. vol 5. 2014-10-21. PMID:24556681. |
using the cerebral cortex of wt and tlr4-knockout mice with and without chronic ethanol treatment, we demonstrate that ethanol induces poly-ubiquitinated proteins accumulation and promotes immunoproteasome activation by inducing the expression of β2i, β5i and pa28α, although it decreases the 20s constitutive proteasome subunits (α2, β5). |
2014-10-21 |
2023-08-12 |
mouse |
| A Pla, M Pascual, J Renau-Piqueras, C Guerr. TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain. Cell death & disease. vol 5. 2014-10-21. PMID:24556681. |
in summary, the present results provide the first evidence demonstrating that chronic ethanol treatment causes proteolysis dysfunctions in the mouse cerebral cortex and that these events are tlr4 dependent. |
2014-10-21 |
2023-08-12 |
mouse |