| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Silvia Alfonso-Loeches, Juan R Ureña-Peralta, Maria José Morillo-Bargues, Jorge Oliver-De La Cruz, Consuelo Guerr. Role of mitochondria ROS generation in ethanol-induced NLRP3 inflammasome activation and cell death in astroglial cells. Frontiers in cellular neuroscience. vol 8. 2014-08-19. PMID:25136295. |
here we show that chronic ethanol treatment increases the co-localization of caspase-1 with gfap(+) cells, and up-regulates il-1β and il-18 in the frontal medial cortex in wt, but not in tlr4 knockout mice. |
2014-08-19 |
2023-08-13 |
mouse |
| Justin T Gass, Heather Trantham-Davidson, Amanda S Kassab, William B Glen, M Foster Olive, L Judson Chandle. Enhancement of extinction learning attenuates ethanol-seeking behavior and alters plasticity in the prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 22. 2014-08-05. PMID:24872560. |
these results confirm changes in the prl and ifl cortex in glutamatergic neurotransmission during extinction learning and demonstrate that manipulation of mglur5 facilitates extinction of ethanol cues in association with neuronal plasticity. |
2014-08-05 |
2023-08-13 |
rat |
| Dan Goldowitz, Alexandre A Lussier, Julia K Boyle, Kaelan Wong, Scott L Lattimer, Candis Dubose, Lu Lu, Michael S Kobor, Kristin M Hamr. Molecular pathways underpinning ethanol-induced neurodegeneration. Frontiers in genetics. vol 5. 2014-07-31. PMID:25076964. |
tissue was collected 7 h after the initial ethanol treatment and analyzed by activated caspase-3 immunostaining to visualize dying cells in the cerebral cortex and hippocampus. |
2014-07-31 |
2023-08-13 |
mouse |
| Dan Goldowitz, Alexandre A Lussier, Julia K Boyle, Kaelan Wong, Scott L Lattimer, Candis Dubose, Lu Lu, Michael S Kobor, Kristin M Hamr. Molecular pathways underpinning ethanol-induced neurodegeneration. Frontiers in genetics. vol 5. 2014-07-31. PMID:25076964. |
furthermore, analysis of chromatin modifications in the cerebral cortex revealed a global increase in γh2ax levels following ethanol exposure, but did not show any change in h3k14 acetylation levels. |
2014-07-31 |
2023-08-13 |
mouse |
| Najeeb Ullah, Muhammad Imran Naseer, Ikram Ullah, Tae Hyun Kim, Hae Young Lee, Myeong Ok Ki. Neuroprotective profile of pyruvate against ethanol-induced neurodegeneration in developing mice brain. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 34. issue 12. 2014-07-23. PMID:23494720. |
exposure of developing mice to ethanol (2.5 g/kg) induces apoptotic neurodegeneration and widespread neuronal cell death in the cortex and thalamus. |
2014-07-23 |
2023-08-12 |
mouse |
| Najeeb Ullah, Muhammad Imran Naseer, Ikram Ullah, Tae Hyun Kim, Hae Young Lee, Myeong Ok Ki. Neuroprotective profile of pyruvate against ethanol-induced neurodegeneration in developing mice brain. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 34. issue 12. 2014-07-23. PMID:23494720. |
immunohistochemical analysis and tunnel at 24 h showed that apoptotic cell death induced by ethanol in the cortex and thalamus is reduced by pyruvate. |
2014-07-23 |
2023-08-12 |
mouse |
| Najeeb Ullah, Muhammad Imran Naseer, Ikram Ullah, Tae Hyun Kim, Hae Young Lee, Myeong Ok Ki. Neuroprotective profile of pyruvate against ethanol-induced neurodegeneration in developing mice brain. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 34. issue 12. 2014-07-23. PMID:23494720. |
the results showed that ethanol increased the expression of caspase-3 and thus induced apoptotic neurodegeneration in the developing mice cortex and thalamus, while co-treatment of pyruvate inhibits the induction of caspase-3 and reduced the cell death in these brain regions. |
2014-07-23 |
2023-08-12 |
mouse |
| Qianqian Yu, Nengneng Cheng, Xiaojun N. Identifying 2 prenylflavanones as potential hepatotoxic compounds in the ethanol extract of Sophora flavescens. Journal of food science. vol 78. issue 11. 2014-07-08. PMID:24245902. |
zhixue capsule is composed of ethanol extracts of cortex dictamni (ecd) and sophora flavescens (esf). |
2014-07-08 |
2023-08-12 |
human |
| S N Kozhechkin, Yu S Mednikova, L G Koli. Effects of naltrexone on firing activity of rat cortex neurons and its interactions with ethanol. Bulletin of experimental biology and medicine. vol 155. issue 5. 2014-07-08. PMID:24288728. |
effects of naltrexone on firing activity of rat cortex neurons and its interactions with ethanol. |
2014-07-08 |
2023-08-12 |
rat |
| Michiko Oka, Masaaki Hirouchi, Masaru Tamura, Seishi Sugahara, Tatsuya Oyam. Acamprosate {monocalcium bis(3-acetamidopropane-1-sulfonate)} reduces ethanol-drinking behavior in rats and glutamate-induced toxicity in ethanol-exposed primary rat cortical neuronal cultures. European journal of pharmacology. vol 718. issue 1-3. 2014-06-10. PMID:24012782. |
after exposure of primary neuronal cultures of rat cerebral cortex to ethanol for four days, neurotoxicity, as measured by the extracellular leakage of lactate dehydrogenase (ldh), was induced by incubation with glutamate for 1h followed by incubation in the absence of ethanol for 24h. |
2014-06-10 |
2023-08-12 |
rat |
| Vivek Tiwari, Pandichelvam Veeraiah, Vaidyanathan Subramaniam, Anant Bahadur Pate. Differential effects of ethanol on regional glutamatergic and GABAergic neurotransmitter pathways in mouse brain. Journal of neurochemistry. vol 128. issue 5. 2014-04-29. PMID:24164397. |
(1)h mrs measurement suggests that depletion of ethanol from cerebral cortex follows zero order kinetics with rate 0.18 ± 0.04 μmol/g/min. |
2014-04-29 |
2023-08-12 |
mouse |
| S R Marcus, M V Chandrakala, H A Nadige. Interaction between vitamin E and glutathione in rat brain: Effect of chronic ethanol administration. Asia Pacific journal of clinical nutrition. vol 7. issue 3/4. 2014-01-08. PMID:24393672. |
a study of the levels of gsh and activities of glutathione peroxidase (gp), glutathione reductase (gr) and glutathione transferase (gst) in the cerebral cortex (cc), cerebellum (cb) and brain stem (bs) of vitamin e-supplemented and -deficient rats subjected to ethanol administration for 30 days was carried out. |
2014-01-08 |
2023-08-12 |
rat |
| E K Orenberg, J Renson, J D Barcha. The effects of alcohol on cyclic AMP in mouse brain. Neurochemical research. vol 1. issue 6. 2013-11-26. PMID:24271749. |
whole-brain camp content was decreased with ethanol injection at all doses (0.4-3.2 g/kg), and reflected the decreased levels in the cortex. |
2013-11-26 |
2023-08-12 |
mouse |
| E K Orenberg, J Renson, J D Barcha. The effects of alcohol on cyclic AMP in mouse brain. Neurochemical research. vol 1. issue 6. 2013-11-26. PMID:24271749. |
in all brain areas, significant changes in camp content occur within 10 min after ethanol injection; elevated levels persist for 30-60 min in the subcortex and cerebellum, but remain significantly depressed in the cortex at 3 h. these dynamic changes in brain camp levels after ethanol administration may reflect variations in neurotransmitter activity. |
2013-11-26 |
2023-08-12 |
mouse |
| Jie Wang, Hongying Du, Lihong Jiang, Xiaoxian Ma, Robin A de Graaf, Kevin L Behar, Graeme F Maso. Oxidation of ethanol in the rat brain and effects associated with chronic ethanol exposure. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 35. 2013-11-22. PMID:23940368. |
ethanol oxidation was seen to occur both in the cortex and the subcortex. |
2013-11-22 |
2023-08-12 |
rat |
| Jie Wang, Hongying Du, Lihong Jiang, Xiaoxian Ma, Robin A de Graaf, Kevin L Behar, Graeme F Maso. Oxidation of ethanol in the rat brain and effects associated with chronic ethanol exposure. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 35. 2013-11-22. PMID:23940368. |
(13)c labeling from subcortical oxidation of ethanol was similar to that seen in cortex but was not affected by chronic ethanol exposure. |
2013-11-22 |
2023-08-12 |
rat |
| Silvia Alfonso-Loeches, María Pascual, Consuelo Guerr. Gender differences in alcohol-induced neurotoxicity and brain damage. Toxicology. vol 311. issue 1-2. 2013-10-25. PMID:23500890. |
using the brains of tlr4(+/+) and tlr4(-/-) (tlr4-ko) mice, we report that chronic ethanol treatment induces inflammatory mediators (inos and cox-2), cytokines (il-1β, tnf-α), gliosis processes, caspase-3 activation and neuronal loss in the cerebral cortex of both female and male mice. |
2013-10-25 |
2023-08-12 |
mouse |
| Maria Carolina Fabio, Samanta M March, Juan Carlos Molina, Michael E Nizhnikov, Norman E Spear, Ricardo Marcos Pautass. Prenatal ethanol exposure increases ethanol intake and reduces c-Fos expression in infralimbic cortex of adolescent rats. Pharmacology, biochemistry, and behavior. vol 103. issue 4. 2013-10-24. PMID:23266368. |
prenatal ethanol exposure increases ethanol intake and reduces c-fos expression in infralimbic cortex of adolescent rats. |
2013-10-24 |
2023-08-12 |
rat |
| Maria Carolina Fabio, Samanta M March, Juan Carlos Molina, Michael E Nizhnikov, Norman E Spear, Ricardo Marcos Pautass. Prenatal ethanol exposure increases ethanol intake and reduces c-Fos expression in infralimbic cortex of adolescent rats. Pharmacology, biochemistry, and behavior. vol 103. issue 4. 2013-10-24. PMID:23266368. |
adolescents prenatally exposed to ethanol as fetuses exhibited reduced neural activity in infralimbic cortex (but not in prelimbic cortex or nucleus accumbens core or shell), an area that has been implicated in the extinction of drug-mediated associative memories. |
2013-10-24 |
2023-08-12 |
rat |
| S Alex Marshall, Justin A McClain, Matthew L Kelso, Deann M Hopkins, James R Pauly, Kimberly Nixo. Microglial activation is not equivalent to neuroinflammation in alcohol-induced neurodegeneration: The importance of microglia phenotype. Neurobiology of disease. vol 54. 2013-10-21. PMID:23313316. |
following a four-day binge ethanol paradigm, rat hippocampal and entorhinal cortex tissue was examined using three distinct approaches to determine microglia phenotype and bbb disruption: immunohistochemistry, autoradiography, and elisa. |
2013-10-21 |
2023-08-12 |
rat |