| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior vol issue 2023 36870422 |
the present study demonstrated for the first time that acute as well as subchronic (4\xe2\x80\xafdays) administration of the experimental ghs-r1a antagonist jmv2959 in usual intraperitoneal doses including 3\xe2\x80\xafmg/kg, had no influence on memory functions tested in the morris water maze in rats as well as no significant effects on the molecular markers linked with memory processing in selected brain areas in rats, specifically on the \xce\xb2-actin, c-fos, two forms of the calcium/calmodulin-dependent protein kinase ii (camkii, p-camkii) and the camp-response element binding protein (creb, p-creb), within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum, and hippocampus (hipp). |
2023-03-04 |
2023-03-06 |
rat |
| Jameel N Hamdan, Jorge A Sierra-Fonseca, Rodolfo J Flores, Sigifredo Saucedo, Manuel Miranda-Arango, Laura E O'Dell, Kristin L Gosselin. Early-life adversity increases anxiety-like behavior and modifies synaptic protein expression in a region-specific manner. Frontiers in behavioral neuroscience vol 16 issue 2022 36338879 |
the hippocampus (hipp), medial prefrontal cortex (mpfc), nucleus accumbens (nac), and caudate putamen (cpu) were isolated from one subgroup of animals and subjected to western blot and protein quantitation for tyrosine hydroxylase (th), \xce\xb1-synuclein (alpha), nmda receptor (nmdar), dopamine receptor-1 (d1) and -2 (d2), dopamine transporter (dat), and postsynaptic density 95 (psd95). |
2022-11-07 |
2023-01-30 |
rat |
| Tong Zhang, Naoya Nishitani, Kazuhei Niitani, Ryoma Nishida, Yusaku Futami, Satoshi Deyama, Katsuyuki Kaned. A spatiotemporal increase of neuronal activity accompanies the motivational effect of wheel running in mice. Behavioural brain research vol issue 2022 35777550 |
immunohistochemical analyses revealed that the number of c-fos (a neuronal activity marker)-positive cells increased in the medial prefrontal cortex (mpfc), core and shell of the nucleus accumbens (nac), dorsal striatum (str), and lateral septum (ls) at day 1, day 9, and days 20-24, in a time-dependent manner. |
2022-07-01 |
2023-01-27 |
mouse |
| Cai-N Cheng, Shaw-Jye Wu, Andrew Chih Wei Huan. Environmental Enrichment Components Required to Reduce Methamphetamine-Induced Behavioral Sensitization in Mice: Examination of Behaviors and Neural Substrates. Journal of clinical medicine vol 11 issue 11 2022 35683439 |
the c-fos expression analysis showed that the medial prefrontal cortex (i.e., cingulate cortex 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), nucleus accumbens (nac), basolateral amygdala (bla), ventral tegmental area (vta), caudate-putamen (cpu), and hippocampus (i.e., ca1, ca3, and dentate gyrus (dg)) contributed to mamph-induced behavioral sensitization. |
2022-06-10 |
2023-01-27 |
mouse |
| Tomoyuki Ijiro, Atsushi Yaguchi, Ayaka Yokoyama, Sumiyoshi Kiguch. Rovatirelin ameliorates motor dysfunction in the cytosine arabinoside-induced rat model of spinocerebellar degeneration via acetylcholine and dopamine neurotransmission. Clinical and experimental pharmacology & physiology vol issue 2022 35637550 |
moreover, rovatirelin significantly increased acetylcholine (ach) levels in the medial prefrontal cortex (mpfc) and dopamine (da) levels in the nucleus accumbens (nac) at \xe2\x89\xa53 mg/kg and significantly increased da levels in the dorsal striatum at \xe2\x89\xa510 mg/kg in normal rats. |
2022-05-31 |
2023-01-27 |
rat |
| Kevin Clare, Chelsea Pan, Gloria Kim, Kicheon Park, Juan Zhao, Nora D Volkow, Zhicheng Lin, Congwu D. Cocaine Reduces the Neuronal Population While Upregulating Dopamine D2-Receptor-Expressing Neurons in Brain Reward Regions: Sex-Effects. Frontiers in pharmacology vol 12 issue 2021 33912043 |
here, we investigated changes in the total neuronal density and relative concentration of d2r-expressing neurons in the medial prefrontal cortex (mpfc), dorsal striatum (dstr), nucleus accumbens (nac), and ventral tegmental area (vta) in both male and female mice passively exposed to cocaine for two weeks. |
2021-12-12 |
2023-01-26 |
mouse |
| Maria Vrettou, Liying Yan, Kent W Nilsson, \\xc3\\x85sa Wall\\xc3\\xa9n-Mackenzie, Ingrid Nylander, Erika Comasc. DNA methylation of Vesicular Glutamate Transporters in the mesocorticolimbic brain following early-life stress and adult ethanol exposure-an explorative study. Scientific reports vol 11 issue 1 2021 34321562 |
the present study aimed to investigate whether dna methylation of the vesicular glutamate transporters (vglut)1-3 is related to previously observed vglut1-3 transcriptional differences in the ventral tegmental area (vta), nucleus accumbens (acb), dorsal striatum (dstr) and medial prefrontal cortex (mpfc) of adult rats exposed to els, modelled by maternal separation, and voluntary ethanol consumption. |
2021-11-08 |
2023-01-26 |
rat |
| Anna Solarz, Iwona Majcher-Ma\\xc5\\x9blanka, Agnieszka Chocy. Effects of early-life stress and sex on blood-brain barrier permeability and integrity in juvenile and adult rats. Developmental neurobiology vol 81 issue 7 2021 34320279 |
we used the maternal separation (ms) procedure in rats to model els and evaluated bbb permeability and gene expression of selected tight junction (tj) proteins, glucose transporter type 1 (slc2a1) and aquaporin 4 (aqp4) in the medial prefrontal cortex (mpfc), dorsal striatum (dstr) and hippocampus of juvenile and adult rats. |
2021-10-15 |
2023-01-26 |
rat |
| Adrienne N Santiago, Emily A Makowicz, Muzi Du, Chiye Aok. Food Restriction Engages Prefrontal Corticostriatal Cells and Local Microcircuitry to Drive the Decision to Run versus Conserve Energy. Cerebral cortex (New York, N.Y. : 1991) vol 31 issue 6 2021 33497440 |
here, we demonstrate that chemogenetic activation of either the general medial prefrontal cortex (mpfc) pyramidal cell population, or the subpopulation projecting to dorsal striatum (ds) drives running specifically during hours preceding limited food availability, and not during ad libitum food availability. |
2021-10-11 |
2023-01-26 |
human |
| Christina Strauch, Thu-Huong Hoang, Frank Angenstein, Denise Manahan-Vaugha. Olfactory Information Storage Engages Subcortical and Cortical Brain Regions That Support Valence Determination. Cerebral cortex (New York, N.Y. : 1991) vol issue 2021 34379749 |
we detected bold signal increases in the anterior olfactory nucleus (aon), pc and entorhinal cortex, nucleus accumbens, dorsal striatum, ventral diagonal band of broca, prelimbic-infralimbic cortex (prl-il), dorsal medial prefrontal cortex, and basolateral amygdala. |
2021-08-11 |
2023-01-26 |
Not clear |
| Miguel Skirzewski, Marie E Cronin, Ricardo Murphy, Wambura Fobbs, Alexxai V Kravitz, Andres Buonann. ErbB4 Null Mice Display Altered Mesocorticolimbic and Nigrostriatal Dopamine Levels as well as Deficits in Cognitive and Motivational Behaviors. eNeuro vol 7 issue 3 2021 32354758 |
here, we report that extracellular steady-state levels of da are reduced in the medial prefrontal cortex (mpfc; -65%), hippocampus (-53%) and nucleus accumbens (nac; -35%), but are elevated in the dorsal striatum (+25%) of erbb4 knock-out mice (erbb4 kos) relative to wild-type controls. |
2021-06-18 |
2023-01-26 |
mouse |
| Jakub Kraus, Robert Roman, Lenka Jurkovi\\xc4\\x8dov\\xc3\\xa1, Radek Mare\\xc4\\x8dek, Michal Mikl, Milan Br\\xc3\\xa1zdil, Andreas Fric. Social support modulates subjective and neural responses to sad mental imagery. Behavioural brain research vol 380 issue 2021 31843658 |
we found that mental imagery of a recently deceased loved one was associated with increased reactivity in the dorsal striatum, medial prefrontal cortex, anterior and posterior cingulate cortex, thalamus and cerebellum. |
2021-05-03 |
2023-01-26 |
Not clear |
| Camilla d'Angelo, Dawn M Eagle, Cristina-M Coman, Trevor W Robbin. Role of the medial prefrontal cortex and nucleus accumbens in an operant model of checking behaviour and uncertainty. Brain and neuroscience advances vol 1 issue 2021 29900415 |
the present study used the observing response task to investigate checking behaviour following excitotoxic lesions of the medial prefrontal cortex, nucleus accumbens core and dorsal striatum, brain regions considered to be of relevance to obsessive-compulsive disorder. |
2021-03-04 |
2023-01-26 |
rat |
| A S\\xc3\\xa1nchez-Gonz\\xc3\\xa1lez, I Oliveras, C R\\xc3\\xado-\\xc3\\x81lamos, M A Piludu, C Gerbol\\xc3\\xa9s, C Tapias-Espinosa, A Tobe\\xc3\\xb1a, S Aznar, A Fern\\xc3\\xa1ndez-Terue. Dissociation between schizophrenia-relevant behavioral profiles and volumetric brain measures after long-lasting social isolation in Roman rats. Neuroscience research vol 155 issue 2021 31306676 |
the aim here was to further investigate the neuroanatomical effects of the isolation rearing, estimated through volume differences in medial prefrontal cortex (mpfc), dorsal striatum (dst) and hippocampus (hpc). |
2021-02-23 |
2023-01-26 |
rat |
| Xixi Yang, Yichong Wen, Yuxiang Zhang, Feifei Gao, Jingsi Yang, Zhuojin Yang, Chunxia Ya. Dynamic Changes of Cytoskeleton-Related Proteins Within Reward-Related Brain Regions in Morphine-Associated Memory. Frontiers in neuroscience vol 14 issue 2021 33584180 |
compared with the nac and dorsal hippocampus, dynamic changes in the medial prefrontal cortex (mpfc) and caudate putamen (cpu) were not very significant. |
2021-02-16 |
2023-01-26 |
mouse |
| Giulia Costa, Marcello Serra, Jacopo Marongiu, Micaela Morelli, Nicola Simol. Influence of dopamine transmission in the medial prefrontal cortex and dorsal striatum on the emission of 50-kHz ultrasonic vocalizations in rats treated with amphetamine: Effects on drug-stimulated and conditioned calls. Progress in neuro-psychopharmacology & biological psychiatry vol 97 issue 2021 31669508 |
influence of dopamine transmission in the medial prefrontal cortex and dorsal striatum on the emission of 50-khz ultrasonic vocalizations in rats treated with amphetamine: effects on drug-stimulated and conditioned calls. |
2021-01-18 |
2023-01-26 |
rat |
| Giulia Costa, Marcello Serra, Jacopo Marongiu, Micaela Morelli, Nicola Simol. Influence of dopamine transmission in the medial prefrontal cortex and dorsal striatum on the emission of 50-kHz ultrasonic vocalizations in rats treated with amphetamine: Effects on drug-stimulated and conditioned calls. Progress in neuro-psychopharmacology & biological psychiatry vol 97 issue 2021 31669508 |
to clarify this issue, we evaluated 50-khz usv emissions in rats subjected to dopaminergic denervation of either the medial prefrontal cortex (mpfc) or the dorsal striatum (ds) and treated with amphetamine. |
2021-01-18 |
2023-01-26 |
rat |
| Mei Huang, Wenqi He, Lakshmi Rajagopal, Andrea Kudwa, Dimitri E Grigoriadis, Herbert Y Meltze. Effects of NBI-98782, a selective vesicular monoamine transporter 2 (VMAT2) inhibitor, on neurotransmitter efflux and phencyclidine-induced locomotor activity: Relevance to tardive dyskinesia and antipsychotic action. Pharmacology, biochemistry, and behavior vol 190 issue 2021 32084491 |
we utilized microdialysis in awake, freely moving mice to determine the effect of nbi-98782, the active metabolite of valbenazine, alone, or in combination with several antipsychotic drugs (apds), to influence neurotransmitter efflux in the medial prefrontal cortex (mpfc), dorsal striatum (dstr), hippocampus and nucleus accumbens (nac); we also compared it with tetrabenazine, the prototypical vmat2 inhibitor. |
2021-01-07 |
2023-01-26 |
mouse |
| Elisabetta F Buonaguro, Sara Morley-Fletcher, Camilla Avagliano, Licia Vellucci, Felice Iasevoli, Hammou Bouwalerh, Gilles Van Camp, Ferdinando Nicoletti, Stefania Maccari, Andrea de Bartolomei. Glutamatergic postsynaptic density in early life stress programming: Topographic gene expression of mGlu5 receptors and Homer proteins. Progress in neuro-psychopharmacology & biological psychiatry vol 96 issue 2021 31404590 |
to this end, we investigated unconditioned behavioral response using the light/dark box test, as well as the expression of psd genes (homer1a, homer1b, and grm5), in the medial prefrontal cortex, cortex, caudate-putamen, amygdala, and dorsal hippocampus. |
2021-01-04 |
2023-01-26 |
rat |
| Yuanshu Chen, Qin Li, Qianqian Zhang, Juan Kou, Yingying Zhang, Han Cui, Jennifer Wernicke, Christian Montag, Benjamin Becker, Keith M Kendrick, Shuxia Ya. The Effects of Intranasal Oxytocin on Neural and Behavioral Responses to Social Touch in the Form of Massage. Frontiers in neuroscience vol 14 issue 2020 33343285 |
intranasal oxytocin significantly increased subjective pleasantness ratings of the manual but not the machine massage and neural responses in key regions involved in reward (orbitofrontal cortex, dorsal striatum and ventral tegmental area), social cognition (superior temporal sulcus and inferior parietal lobule), emotion and salience (amygdala and anterior cingulate and insula) and default mode networks (medial prefrontal cortex, parahippocampal gyrus, posterior cingulate, and precuneus) as well as a number of sensory and motor processing regions. |
2020-12-22 |
2023-01-26 |
human |