| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Akina Harada, Kazunori Suzuki, Naomi Kamiguchi, Maki Miyamoto, Kimio Tohyama, Kosuke Nakashima, Takahiko Taniguchi, Haruhide Kimur. Characterization of binding and inhibitory properties of TAK-063, a novel phosphodiesterase 10A inhibitor. PloS one. vol 10. issue 3. 2016-02-23. PMID:25815469. |
in vitro autoradiography (arg) studies using rat brain sections revealed that [3h]tak-063 selectively accumulated in the caudate putamen (cpu), nucleus accumbens (nac), globus pallidus, substantia nigra, and striatonigral projection, where pde10a is highly expressed. |
2016-02-23 |
2023-08-13 |
mouse |
| Daniel Dautan, Husniye Hacioğlu Bay, J Paul Bolam, Todor V Gerdjikov, Juan Mena-Segovi. Extrinsic Sources of Cholinergic Innervation of the Striatal Complex: A Whole-Brain Mapping Analysis. Frontiers in neuroanatomy. vol 10. 2016-02-02. PMID:26834571. |
although early studies suggested that acetylcholine in the striatum (str) is derived almost exclusively from cholinergic interneurons (cin), recent axonal mapping studies using conditional anterograde tracing have revealed the existence of a prominent direct cholinergic pathway from the pedunculopontine and laterodorsal tegmental nuclei to the dorsal striatum and nucleus accumbens. |
2016-02-02 |
2023-08-13 |
Not clear |
| B ZióŁkowska, A Gieryk, W Solecki, R PrzewŁock. Temporal and anatomic patterns of immediate-early gene expression in the forebrain of C57BL/6 and DBA/2 mice after morphine administration. Neuroscience. vol 284. 2015-12-22. PMID:25290009. |
at 30 min, one or more iegs were induced in circumscribed subregions of the dorsal striatum (dstr) and of the nucleus accumbens (nac) shell, as well as in the lateral septum. |
2015-12-22 |
2023-08-13 |
mouse |
| Juan Li, Lei Zhang, Zhenzhong Chen, Minjuan Xie, Lu Huang, Jinhua Xue, Yutong Liu, Nuyun Liu, Fukun Guo, Yi Zheng, Jiming Kong, Lin Zhang, Lu Zhan. Cocaine activates Rac1 to control structural and behavioral plasticity in caudate putamen. Neurobiology of disease. vol 75. 2015-11-20. PMID:25595128. |
repeated exposure to cocaine was previously found to cause sensitized behavioral responses and structural remodeling on medium spiny neurons of the nucleus accumbens (nac) and caudate putamen (cpu). |
2015-11-20 |
2023-08-13 |
Not clear |
| Klemencja Berghauzen-Maciejewska, Jadwiga Wardas, Barbara Kosmowska, Urszula Głowacka, Katarzyna Kuter, Krystyna Ossowsk. Alterations of BDNF and trkB mRNA expression in the 6-hydroxydopamine-induced model of preclinical stages of Parkinson's disease: an influence of chronic pramipexole in rats. PloS one. vol 10. issue 3. 2015-11-20. PMID:25739024. |
the lesion did not influence bdnf and trkb expression in the caudate-putamen, substantia nigra, nucleus accumbens (shell and core) and ventral tegmental area (vta). |
2015-11-20 |
2023-08-13 |
rat |
| Richard Exley, Michael A Clements, Henrike Hartung, J Michael McIntosh, Michael Franklin, Isabel Bermudez, Stephanie J Crag. Striatal dopamine transmission is reduced after chronic nicotine with a decrease in α6-nicotinic receptor control in nucleus accumbens. The European journal of neuroscience. vol 38. issue 7. 2015-10-30. PMID:23841846. |
here, we explored whether chronic nicotine exposure modifies striatal da transmission, whether the effects of acute nicotine on da release probability persist and whether there are modifications to the regulation of da release by α6-subunit-containing (*) relative to non-α6* nachrs in nucleus accumbens (nac) and in caudate-putamen (cpu). |
2015-10-30 |
2023-08-12 |
mouse |
| Ludmila Brunerová, Michal Andě. [Food intake regulation - 2nd part]. Vnitrni lekarstvi. vol 60. issue 1. 2015-10-16. PMID:24564775. |
dopamine in dorsal striatum via d2 receptors generates food motivation as a key means of survival, however in ventral striatum (nucleus accumbens) is responsible for motivation to food bringing pleasure. |
2015-10-16 |
2023-08-12 |
Not clear |
| Matthew F Lazenka, Aaron J Tomarchio, Aron H Lichtman, Paul Greengard, Marc Flajolet, Dana E Selley, Laura J Sim-Selle. Role of Dopamine Type 1 Receptors and Dopamine- and cAMP-Regulated Phosphoprotein Mr 32 kDa in Δ9-Tetrahydrocannabinol-Mediated Induction of ΔFosB in the Mouse Forebrain. The Journal of pharmacology and experimental therapeutics. vol 354. issue 3. 2015-10-06. PMID:26099530. |
Δ(9)-tetrahydrocannabinol (thc), the main psychoactive component of marijuana, produces motor and motivational effects via interactions with the dopaminergic system in the caudate-putamen and nucleus accumbens. |
2015-10-06 |
2023-08-13 |
mouse |
| Klemencja Berghauzen-Maciejewska, Katarzyna Kuter, Wacław Kolasiewicz, Urszula Głowacka, Anna Dziubina, Krystyna Ossowska, Jadwiga Warda. Pramipexole but not imipramine or fluoxetine reverses the "depressive-like" behaviour in a rat model of preclinical stages of Parkinson's disease. Behavioural brain research. vol 271. 2015-08-14. PMID:24956561. |
this treatment induced moderate decreases in the levels of dopamine and its metabolites in the caudate-putamen, nucleus accumbens and frontal cortex and reduced the density of tyrosine hydroxylase-immunoreactive neurons in the substantia nigra pars compacta and ventral tegmental area. |
2015-08-14 |
2023-08-13 |
rat |
| Jiamei Lian, Xu-Feng Huang, Nagesh Pai, Chao Den. Chronic betahistine co-treatment reverses olanzapine's effects on dopamine D₂ but not 5-HT2A/2C bindings in rat brains. Progress in neuro-psychopharmacology & biological psychiatry. vol 56. 2015-07-31. PMID:25149912. |
this study investigated the effects of chronic treatment of olanzapine and/or betahistine on the binding density of the serotonergic 5-ht2a (5-ht2ar) and 5-ht2c (5-ht2cr) receptors, 5-ht transporter (5-htt), and dopaminergic d₂ receptors (d₂r) in the brain regions involved in antipsychotic efficacy, including the prefrontal cortex (pfc), cingulate cortex (cg), nucleus accumbens (nac), and caudate putamen (cpu). |
2015-07-31 |
2023-08-13 |
rat |
| Maria Constanza Paz, Natalia Andrea Marchese, Maria Mercedes Stroppa, Nelia Marta Gerez de Burgos, Hans Imboden, Gustavo Baiardi, Liliana Marina Cancela, Claudia Bregonzi. Involvement of the brain renin-angiotensin system (RAS) in the neuroadaptive responses induced by amphetamine in a two-injection protocol. Behavioural brain research. vol 272. 2015-07-16. PMID:25046593. |
wistar male rats, pretreated with amphetamine were used 7 or 21 days later to study at1 receptors by immunohistochemistry and western blot and also angiotensinogen mrna and protein in caudate putamen and nucleus accumbens. |
2015-07-16 |
2023-08-13 |
rat |
| Haiyin Wu, Brian O'Neill, Dawn D Han, Keerthi Thirtamara-Rajamani, Yanlin Wang, Howard H G. Restoration of cocaine stimulation and reward by reintroducing wild type dopamine transporter in adult knock-in mice with a cocaine-insensitive dopamine transporter. Neuropharmacology. vol 86. 2015-07-14. PMID:24835281. |
in an earlier study we showed that aav-datwt injections in regions covering the lateral nucleus accumbens (nac) and lateral caudate-putamen (cpu) restored cocaine stimulation but not cocaine reward. |
2015-07-14 |
2023-08-13 |
mouse |
| Delphine Révy, Florence Jaouen, Pascal Salin, Christophe Melon, Dorian Chabbert, Elisiana Tafi, Lena Concetta, Francina Langa, Marianne Amalric, Lydia Kerkerian-Le Goff, Hélène Marie, Corinne Beurrie. Cellular and behavioral outcomes of dorsal striatonigral neuron ablation: new insights into striatal functions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 11. 2015-06-15. PMID:24903652. |
dt-mediated ablation of striatonigral msns caused selective loss of cholinergic interneurons in the dorsal striatum but not in the ventral striatum (nucleus accumbens), suggesting a region-specific critical role of the direct pathway in striatal cholinergic neuron homeostasis. |
2015-06-15 |
2023-08-13 |
mouse |
| P Abate, K Hernández-Fonseca, A C Reyes-Guzmán, I G Barbosa-Luna, M Ménde. Prenatal ethanol exposure alters met-enkephalin expression in brain regions related with reinforcement: possible mechanism for ethanol consumption in offspring. Behavioural brain research. vol 274. 2015-05-26. PMID:25150040. |
met-enk content was assessed in the ventral tegmental area [vta], nucleus accumbens [nacc], prefrontal cortex [pfc], substantia nigra [sn], caudate-putamen [cp], amygdala, hypothalamus and hippocampus. |
2015-05-26 |
2023-08-13 |
rat |
| Elizabeth D Cummins, Stephen B Griffin, Chase M Duty, Daniel J Peterson, Katherine C Burgess, Russell W Brow. The role of dopamine D₁ and D₂ receptors in adolescent methylphenidate conditioned place preference: sex differences and brain-derived neurotrophic factor. Developmental neuroscience. vol 36. issue 3-4. 2015-04-17. PMID:24821360. |
this study analyzed the role of dopamine d1 and d2 receptors in methylphenidate (mph) conditioned place preference (cpp) in adolescent male and female rats, in addition to the role of these receptors in the effects of mph on brain-derived neurotrophic factor (bdnf) in the dorsal striatum and nucleus accumbens. |
2015-04-17 |
2023-08-13 |
rat |
| Zhenzhen Hu, Eun-Hye Oh, Yeon Bok Chung, Jin Tae Hong, Ki-Wan O. Predominant D1 Receptors Involvement in the Over-expression of CART Peptides after Repeated Cocaine Administration. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 19. issue 2. 2015-03-02. PMID:25729269. |
a higher proportion of cart(+) cells in the cocaine-treated mice were present in the nucleus accumbens (nac) shell than in the dorsolateral (dl) part of caudate putamen (cp). |
2015-03-02 |
2023-08-13 |
mouse |
| Hui-Di Yang, Qian Wang, De-Hua Wan. Food hoarding, but not food intake, is attenuated by acute diazepam treatment in female Mongolian gerbils (Meriones unguiculatus). Hormones and behavior. vol 66. issue 1. 2015-02-07. PMID:24681217. |
this blockade was associated with increased cellular activation in selected brain areas, such as the nucleus accumbens (nacc), caudate putamen (cp) and ventral tegmental area (vta), which suggested that direct activation of gaba in the brain reward circuitry decreased food hoarding in hfh females. |
2015-02-07 |
2023-08-12 |
Not clear |
| Qing Wang, Jin Li, Xiaobo Wei, Jinchi Liao, Yunqi Xu, Tingting Lu, Bing Qin, Junqiang Xie, Chao Deng, Xufeng Huan. Alterations of NMDA receptor binding in various brain regions among 6-hydroxydopamine-induced Parkinsonian rats. The International journal of neuroscience. vol 124. issue 6. 2015-01-12. PMID:24102195. |
in the 6-ohda-induced parkinsonian rat model, nigrostriatal dopaminergic neuron loss significantly mediated the decreased [(3)h] mk-801 binding, predominantly in the hippocampus (-22.4%, p < 0.001), caudate putamen (-14.1%, p < 0.01), accumbens nucleus (-13.8%, p < 0.05), cingulate cortex (-13.4%, p < 0.001), posteromedial cortical amygdala (-14.5%, p < 0.01) and piriform cortex (-9%, p < 0.05) compared to the controls, while there was a profound reduction of tyrosine hydroxylase (th) immunohistochemistry in the substantia nigra pars compacta. |
2015-01-12 |
2023-08-12 |
rat |
| Francesca Felicia Caputi, Manuela Di Benedetto, Donatella Carretta, Sussy Bastias del Carmen Candia, Claudio D'Addario, Chiara Cavina, Sanzio Candeletti, Patrizia Romuald. Dynorphin/KOP and nociceptin/NOP gene expression and epigenetic changes by cocaine in rat striatum and nucleus accumbens. Progress in neuro-psychopharmacology & biological psychiatry. vol 49. 2014-12-31. PMID:24184686. |
the aim of this study was to investigate possible changes of gene expression of the dynorphinergic and nociceptinergic system components in the nucleus accumbens (na) and in medial and lateral caudate putamen (mcpu and lcpu, respectively) of rats, following chronic subcutaneous infusion of cocaine. |
2014-12-31 |
2023-08-12 |
rat |
| Beata Bystrowska, Irena Smaga, Małgorzata Frankowska, Małgorzata Fili. Changes in endocannabinoid and N-acylethanolamine levels in rat brain structures following cocaine self-administration and extinction training. Progress in neuro-psychopharmacology & biological psychiatry. vol 50. 2014-12-11. PMID:24334211. |
in addition, we detected increases (>150%) in the levels of oea and pea in the limbic areas in both cocaine treated groups, as well as an increase in the tissue levels of oea in the dorsal striatum in only the yoked cocaine group and increases in the tissue levels of pea in the dorsal striatum (both cocaine groups) and the nucleus accumbens (yoked cocaine group only). |
2014-12-11 |
2023-08-12 |
rat |