| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joerg Schreiber, Marlene J Végh, Julia Dawitz, Tim Kroon, Maarten Loos, Dorthe Labonté, Ka Wan Li, Pim Van Nierop, Michiel T Van Diepen, Chris I De Zeeuw, Matthias Kneussel, Rhiannon M Meredith, August B Smit, Ronald E Van Kestere. Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels. The Journal of cell biology. vol 211. issue 3. 2016-02-12. PMID:26527743. |
interestingly, hippocampal deletion of actg1 caused an increase in long-term fear memory. |
2016-02-12 |
2023-08-13 |
mouse |
| Qing-Qing Li, Bao-Ming L. Brain-derived neurotrophic factor in the anterior cingulate cortex is involved in the formation of fear memory. Sheng li xue bao : [Acta physiologica Sinica]. vol 67. issue 5. 2016-02-10. PMID:26490062. |
it has been shown that bdnf in the hippocampus and amygdala participates in the formation of fear memory. |
2016-02-10 |
2023-08-13 |
rat |
| Ivana Machado, Patricia V Gonzalez, Alejandro Vilcaes, Lila Carniglia, Helgi B Schiöth, Mercedes Lasaga, Teresa N Scimonell. Interleukin-1β-induced memory reconsolidation impairment is mediated by a reduction in glutamate release and zif268 expression and α-melanocyte-stimulating hormone prevented these effects. Brain, behavior, and immunity. vol 46. 2016-02-04. PMID:25637483. |
our results demonstrated that il-1β induced a significant decrease of glutamate release after reactivation of the fear memory and this effect was related to calcium concentration in hippocampal synaptosomes. |
2016-02-04 |
2023-08-13 |
Not clear |
| Marcelo Giachero, Gaston D Calfa, Victor A Molin. Hippocampal dendritic spines remodeling and fear memory are modulated by GABAergic signaling within the basolateral amygdala complex. Hippocampus. vol 25. issue 5. 2016-01-13. PMID:25600672. |
hippocampal dendritic spines remodeling and fear memory are modulated by gabaergic signaling within the basolateral amygdala complex. |
2016-01-13 |
2023-08-13 |
Not clear |
| Yi Luo, Jun Zhou, Ming-Xing Li, Peng-Fei Wu, Zhuang-Li Hu, Lan Ni, You Jin, Jian-Guo Chen, Fang Wan. Reversal of aging-related emotional memory deficits by norepinephrine via regulating the stability of surface AMPA receptors. Aging cell. vol 14. issue 2. 2015-12-14. PMID:25564942. |
to address this issue, we examined the role of norepinephrine (ne) and its relevant drug desipramine in the regulation of hippocampal long-term potentiation (ltp), surface expression of ampa receptor, and associative fear memory in rats. |
2015-12-14 |
2023-08-13 |
rat |
| Daisuke Ishii, Daisuke Matsuzawa, Shingo Matsuda, Haruna Tomizawa, Chihiro Sutoh, Eiji Shimiz. Methyl donor-deficient diet during development can affect fear and anxiety in adulthood in C57BL/6J mice. PloS one. vol 9. issue 8. 2015-11-10. PMID:25144567. |
therefore, we examined the effects of methyl donor deficiency during the developmental period on fear memory acquisition/extinction and anxiety-like behavior, and the relevant gene expressions in the hippocampus in juvenile (6-wk) and adult (12-wk) mice. |
2015-11-10 |
2023-08-13 |
mouse |
| Carmel M McDermott, Dan Liu, Catherine Ade, Laura A Schrade. Estradiol replacement enhances fear memory formation, impairs extinction and reduces COMT expression levels in the hippocampus of ovariectomized female mice. Neurobiology of learning and memory. vol 118. 2015-11-10. PMID:25555360. |
estradiol replacement enhances fear memory formation, impairs extinction and reduces comt expression levels in the hippocampus of ovariectomized female mice. |
2015-11-10 |
2023-08-13 |
mouse |
| Lidiane Dal Bosco, Gisele E B Weber, Gustavo M Parfitt, Karina Paese, Carla O F Gonçalves, Tiago M Serodre, Clascídia A Furtado, Adelina P Santos, José M Monserrat, Daniela M Barro. PEGylated carbon nanotubes impair retrieval of contextual fear memory and alter oxidative stress parameters in the rat hippocampus. BioMed research international. vol 2015. 2015-11-10. PMID:25738149. |
the results showed that a short exposure to swcnt-peg impaired fear memory retrieval and caused lipid peroxidation in the hippocampus. |
2015-11-10 |
2023-08-13 |
rat |
| Ali Shahmoradi, Konstantin Radyushkin, Moritz J Rossne. Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 27. 2015-10-26. PMID:26100875. |
s1/2(-/-) mice show enhanced cortex (cx)-dependent remote fear memory formation as well as improved reversal learning, but do not display alterations in hippocampus (hi)-dependent recent fear memory formation. |
2015-10-26 |
2023-08-13 |
mouse |
| Sophie A George, Mariana Rodriguez-Santiago, John Riley, Elizabeth Rodriguez, Israel Liberzo. The effect of chronic phenytoin administration on single prolonged stress induced extinction retention deficits and glucocorticoid upregulation in the rat medial prefrontal cortex. Psychopharmacology. vol 232. issue 1. 2015-10-16. PMID:24879497. |
using the rodent ptsd model, single prolonged stress (sps), we have implicated aberrant excitatory neural transmission and glucocorticoid receptor (gr) upregulation in the medial prefrontal cortex (mpfc) and hippocampus (hpc) in fear memory abnormalities associated with ptsd. |
2015-10-16 |
2023-08-13 |
rat |
| Iris Müller, Gürsel Çalışkan, Oliver Stor. The GAD65 knock out mouse - a model for GABAergic processes in fear- and stress-induced psychopathology. Genes, brain, and behavior. vol 14. issue 1. 2015-10-07. PMID:25470336. |
mice bearing a null mutation of the gad65 gene develop hyperexcitability of the amygdala and hippocampus, and a phenotype of increased anxiety and pathological fear memory reminiscent of posttraumatic stress disorder. |
2015-10-07 |
2023-08-13 |
mouse |
| Timothy J Jarome, Anderson A Butler, Jessica N Nichols, Natasha L Pacheco, Farah D Lubi. NF-κB mediates Gadd45β expression and DNA demethylation in the hippocampus during fear memory formation. Frontiers in molecular neuroscience. vol 8. 2015-10-07. PMID:26441517. |
nf-κb mediates gadd45β expression and dna demethylation in the hippocampus during fear memory formation. |
2015-10-07 |
2023-08-13 |
mouse |
| Timothy J Jarome, Anderson A Butler, Jessica N Nichols, Natasha L Pacheco, Farah D Lubi. NF-κB mediates Gadd45β expression and DNA demethylation in the hippocampus during fear memory formation. Frontiers in molecular neuroscience. vol 8. 2015-10-07. PMID:26441517. |
together, these results support a novel transcriptional role for nf-κb in regulation of gadd45β expression and dna demethylation in hippocampal neurons during fear memory. |
2015-10-07 |
2023-08-13 |
mouse |
| Wei-Jye Lin, Cheng Jiang, Masato Sadahiro, Ozlem Bozdagi, Lucy Vulchanova, Cristina M Alberini, Stephen R Salto. VGF and Its C-Terminal Peptide TLQP-62 Regulate Memory Formation in Hippocampus via a BDNF-TrkB-Dependent Mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 28. 2015-09-24. PMID:26180209. |
in this study, we show in the adult mouse hippocampus that expression of the granin family gene vgf and secretion of its c-terminal vgf-derived peptide tlqp-62 are required for fear memory formation. |
2015-09-24 |
2023-08-13 |
mouse |
| Wei-Jye Lin, Cheng Jiang, Masato Sadahiro, Ozlem Bozdagi, Lucy Vulchanova, Cristina M Alberini, Stephen R Salto. VGF and Its C-Terminal Peptide TLQP-62 Regulate Memory Formation in Hippocampus via a BDNF-TrkB-Dependent Mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 28. 2015-09-24. PMID:26180209. |
we found that hippocampal vgf expression and tlqp-62 levels were transiently induced after fear memory training and that sequestering secreted tlqp-62 peptide in the hippocampus immediately after training impaired memory formation. |
2015-09-24 |
2023-08-13 |
mouse |
| Wei-Jye Lin, Cheng Jiang, Masato Sadahiro, Ozlem Bozdagi, Lucy Vulchanova, Cristina M Alberini, Stephen R Salto. VGF and Its C-Terminal Peptide TLQP-62 Regulate Memory Formation in Hippocampus via a BDNF-TrkB-Dependent Mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 28. 2015-09-24. PMID:26180209. |
a critical role of bdnf-trkb signaling as a downstream effector in vgf/tlqp-62-mediated memory consolidation was further revealed by posttraining activation of bdnf-trkb signaling, which rescued impaired fear memory resulting from hippocampal administration of anti-vgf antibodies or germline vgf ablation in mice. |
2015-09-24 |
2023-08-13 |
mouse |
| Melissa E Wang, Robin K Yuan, Alexander T Keinath, Manuel M Ramos Álvarez, Isabel A Muzzi. Extinction of Learned Fear Induces Hippocampal Place Cell Remapping. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 24. 2015-09-01. PMID:26085635. |
the extinction of learned fear is a hippocampus-dependent process thought to embody new learning rather than erasure of the original fear memory, although it is unknown how these competing contextual memories are represented in the hippocampus. |
2015-09-01 |
2023-08-13 |
mouse |
| Mi Tian, Yan Zeng, Yilan Hu, Xiuxue Yuan, Shumin Liu, Jie Li, Pan Lu, Yao Sun, Lei Gao, Daan Fu, Yi Li, Shasha Wang, Shawn M McClintoc. 7, 8-Dihydroxyflavone induces synapse expression of AMPA GluA1 and ameliorates cognitive and spine abnormalities in a mouse model of fragile X syndrome. Neuropharmacology. vol 89. 2015-07-24. PMID:25229717. |
the study found that 4 weeks of treatment with 7, 8-dhf improved spatial and fear memory, and ameliorated morphological spine abnormalities including the number and elongation of spines in the hippocampus and amygdala. |
2015-07-24 |
2023-08-13 |
mouse |
| Verónica de la Fuente, Noel Federman, María Sol Fustiñana, Gisela Zalcman, Arturo Roman. Calcineurin phosphatase as a negative regulator of fear memory in hippocampus: control on nuclear factor-κB signaling in consolidation and reconsolidation. Hippocampus. vol 24. issue 12. 2015-07-22. PMID:25043904. |
calcineurin phosphatase as a negative regulator of fear memory in hippocampus: control on nuclear factor-κb signaling in consolidation and reconsolidation. |
2015-07-22 |
2023-08-13 |
Not clear |
| Tina B Lonsdorf, Armita Golkar, Kara M Lindström, Jan Haaker, Arne Öhman, Martin Schalling, Martin Ingva. BDNFval66met affects neural activation pattern during fear conditioning and 24 h delayed fear recall. Social cognitive and affective neuroscience. vol 10. issue 5. 2015-07-09. PMID:25103087. |
during early extinction, 24h later, we again observed heightened responses in several regions ascribed to the fear network in met-carriers as opposed to val-carriers (insula, amygdala, hippocampus), which likely reflects fear memory recall. |
2015-07-09 |
2023-08-13 |
human |