| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Georgette M Gafford, Ryan G Parsons, Fred J Helmstette. Memory accuracy predicts hippocampal mTOR pathway activation following retrieval of contextual fear memory. Hippocampus. vol 23. issue 9. 2014-04-09. PMID:23640842. |
we tested whether p70s6 kinase (p70s6k), a key component of the mtor signaling pathway, is activated following retrieval of context fear memory in the dorsal hippocampus (dh) and anterior cingulate cortex (acc) at 1, 10, or 36 days after context fear conditioning. |
2014-04-09 |
2023-08-12 |
Not clear |
| C P Fitzsimons, L W A van Hooijdonk, M Schouten, I Zalachoras, V Brinks, T Zheng, T G Schouten, D J Saaltink, T Dijkmans, D A Steindler, J Verhaagen, F J Verbeek, P J Lucassen, E R de Kloet, O C Meijer, H Karst, M Joels, M S Oitzl, E Vreugdenhi. Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior. Molecular psychiatry. vol 18. issue 9. 2014-03-25. PMID:22925833. |
together, our data demonstrate a key role for the gr in newborn hippocampal cells in mediating their synaptic connectivity and structural as well as functional integration into mature hippocampal circuits involved in fear memory consolidation. |
2014-03-25 |
2023-08-12 |
Not clear |
| Ashley C Chen, Amit Etki. Hippocampal network connectivity and activation differentiates post-traumatic stress disorder from generalized anxiety disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 10. 2014-03-24. PMID:23673864. |
as the hippocampus is implicated in both general anxiety and fear memory, it may be an important brain locus for mapping the similarities and differences among anxiety disorders. |
2014-03-24 |
2023-08-12 |
human |
| Cesar Augusto de Oliveira Coelho, Tatiana Lima Ferreira, Juliana Carlota Kramer Soares, Maria Gabriela Menezes Oliveir. Hippocampal NMDA receptor blockade impairs CREB phosphorylation in amygdala after contextual fear conditioning. Hippocampus. vol 23. issue 7. 2014-01-23. PMID:23460450. |
in contextual fear conditioning (cfc), hippocampus is thought to process environmental stimuli into a configural representation of the context and send it to amygdala nuclei, which current evidences point to be the site of cs-us association and fear memory storage. |
2014-01-23 |
2023-08-12 |
rat |
| Ruo-Yu Wang, Rui-Zhe Phang, Pei-Hsuan Hsu, Wei-Hua Wang, Hsien-Ting Huang, Ingrid Y Li. In vivo knockdown of hippocampal miR-132 expression impairs memory acquisition of trace fear conditioning. Hippocampus. vol 23. issue 7. 2014-01-23. PMID:23520022. |
this approach successfully reduced hippocampal mir-132 expression in both naïve and trace fear conditioned groups, and impaired acquisition of trace fear memory in mice. |
2014-01-23 |
2023-08-12 |
mouse |
| Shingo Matsuda, Daisuke Matsuzawa, Daisuke Ishii, Haruna Tomizawa, Junko Sajiki, Eiji Shimiz. Perinatal exposure to bisphenol A enhances contextual fear memory and affects the serotoninergic system in juvenile female mice. Hormones and behavior. vol 63. issue 5. 2014-01-17. PMID:23567477. |
bpa enhanced fear memory and increased serotonin metabolite (5-hiaa) levels and 5-hiaa/5-ht in the hippocampus, the striatum, the midbrain, the pons, and the medulla oblongata of juvenile female mice. |
2014-01-17 |
2023-08-12 |
mouse |
| Gisella Vetere, Valentina Piserchia, Antonella Borreca, Giovanni Novembre, Massimiliano Aceti, Martine Ammassari-Teul. Reactivating fear memory under propranolol resets pre-trauma levels of dendritic spines in basolateral amygdala but not dorsal hippocampus neurons. Frontiers in behavioral neuroscience. vol 7. 2014-01-06. PMID:24391566. |
reactivating fear memory under propranolol resets pre-trauma levels of dendritic spines in basolateral amygdala but not dorsal hippocampus neurons. |
2014-01-06 |
2023-08-12 |
mouse |
| Christopher L Beeman, Philip S Bauer, Jamie L Pierson, Jennifer J Quin. Hippocampus and medial prefrontal cortex contributions to trace and contextual fear memory expression over time. Learning & memory (Cold Spring Harbor, N.Y.). vol 20. issue 6. 2013-12-19. PMID:23685809. |
previous work has shown that damage to the dorsal hippocampus (dh) occurring at recent, but not remote, timepoints following acquisition produces a deficit in trace conditioned fear memory expression. |
2013-12-19 |
2023-08-12 |
Not clear |
| Gillian A Scullion, Katherine N Hewitt, Marie-Christine Pardo. Corticotropin-releasing factor receptor 1 activation during exposure to novelty stress protects against Alzheimer's disease-like cognitive decline in AβPP/PS1 mice. Journal of Alzheimer's disease : JAD. vol 34. issue 3. 2013-12-02. PMID:23302658. |
although novelty-induced nmdar activation contributed to enhancement of fear memory and synaptophysin levels, antagonism of crfr1 and nmdar prevented the novelty-induced increase in hippocampal synaptophysin levels but reversed the other effects of crfr1 inactivation, i.e., the enhancement of contextual fear extinction and fronto-cortical synaptophysin and psd95 levels. |
2013-12-02 |
2023-08-12 |
mouse |
| Marcelo Giachero, Silvia G Bustos, Gaston Calfa, Victor A Molin. A BDNF sensitive mechanism is involved in the fear memory resulting from the interaction between stress and the retrieval of an established trace. Learning & memory (Cold Spring Harbor, N.Y.). vol 20. issue 5. 2013-10-29. PMID:23589091. |
these findings suggest the involvement of a hippocampal bdnf sensitive mechanism in the stress-promoting influence on the fear memory following retrieval. |
2013-10-29 |
2023-08-12 |
rat |
| Michael J Hylin, Sara A Orsi, Anthony N Moore, Pramod K Das. Disruption of the perineuronal net in the hippocampus or medial prefrontal cortex impairs fear conditioning. Learning & memory (Cold Spring Harbor, N.Y.). vol 20. issue 5. 2013-10-29. PMID:23592037. |
consistent with a role for the hippocampus in memory storage in both delayed and trace fear conditioning, removal of hippocampal pnn disrupted contextual and trace fear memory. |
2013-10-29 |
2023-08-12 |
Not clear |
| Anne Albrecht, Gürsel Çalışkan, Melly S Oitzl, Uwe Heinemann, Oliver Stor. Long-lasting increase of corticosterone after fear memory reactivation: anxiolytic effects and network activity modulation in the ventral hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 3. 2013-10-17. PMID:22968818. |
long-lasting increase of corticosterone after fear memory reactivation: anxiolytic effects and network activity modulation in the ventral hippocampus. |
2013-10-17 |
2023-08-12 |
mouse |
| D R Oliveira, P F Sanada, A C S Filho, G M S Conceição, J M Cerutti, S M Cerutt. Long-term treatment with standardized extract of Ginkgo biloba L. enhances the conditioned suppression of licking in rats by the modulation of neuronal and glial cell function in the dorsal hippocampus and central amygdala. Neuroscience. vol 235. 2013-08-30. PMID:23321541. |
for the first time, we show that long-term treatment with the highest dose of egb improves the fear memory and suggests that increased camp-responsive element-binding protein (creb)-1 and glial fibrillary acidic protein (gfap) mrna and protein (p<0.001) in the dorsal hippocampus and amygdaloid complex and reduced growth and plasticity-associated protein 43 (gap-43) (p<0.01) in the hippocampus are involved in this process. |
2013-08-30 |
2023-08-12 |
rat |
| Olivier Bousiges, Romain Neidl, Monique Majchrzak, Marc-Antoine Muller, Alexandra Barbelivien, Anne Pereira de Vasconcelos, Anne Schneider, Jean-Philippe Loeffler, Jean-Christophe Cassel, Anne-Laurence Boutillie. Detection of histone acetylation levels in the dorsal hippocampus reveals early tagging on specific residues of H2B and H4 histones in response to learning. PloS one. vol 8. issue 3. 2013-08-27. PMID:23469244. |
we measured global histone acetylation levels in the rat hippocampus at an early stage of spatial or fear memory formation. |
2013-08-27 |
2023-08-12 |
rat |
| Yan Zeng, Yakun Liu, Mianyun Wu, Jun Liu, Qi H. Activation of TrkB by 7,8-dihydroxyflavone prevents fear memory defects and facilitates amygdalar synaptic plasticity in aging. Journal of Alzheimer's disease : JAD. vol 31. issue 4. 2013-07-08. PMID:22710915. |
the results show that chronic 7,8-dhf treatments significantly enhanced the activation of phosphorylated trkb at the y515 and y816 sites, increased spine density and number in several brain regions that process fear memory including the amygdala, hippocampus, and prefrontal cortex, facilitated basolateral amygdalar synaptic plasticity, and in turn prevented performance in fear conditioning tasks from declining. |
2013-07-08 |
2023-08-12 |
rat |
| Tine L Gulbrandsen, Fraser T Sparks, Robert J Sutherlan. Interfering with post-learning hippocampal activity does not affect long-term consolidation of a context fear memory outside the hippocampus. Behavioural brain research. vol 240. 2013-06-17. PMID:23201356. |
interfering with post-learning hippocampal activity does not affect long-term consolidation of a context fear memory outside the hippocampus. |
2013-06-17 |
2023-08-12 |
rat |
| Arto Lipponen, Bisrat T Woldemichael, Kestutis Gurevicius, Heikki Tanil. Artificial theta stimulation impairs encoding of contextual fear memory. PloS one. vol 7. issue 11. 2013-05-07. PMID:23133638. |
as expected, fimbria-fornix lesion impaired fear memory and dramatically attenuated hippocampal theta power. |
2013-05-07 |
2023-08-12 |
rat |
| Neil M Fournier, Ronald S Duma. Illuminating hippocampal control of fear memory and anxiety. Neuron. vol 77. issue 5. 2013-04-22. PMID:23473311. |
illuminating hippocampal control of fear memory and anxiety. |
2013-04-22 |
2023-08-12 |
Not clear |
| Kazuhiro Takuma, Hiroyuki Mizoguchi, Yoko Funatsu, Yuko Kitahara, Daisuke Ibi, Hiroyuki Kamei, Toshio Matsuda, Koji Koike, Masaki Inoue, Taku Nagai, Kiyofumi Yamad. Placental extract improves hippocampal neuronal loss and fear memory impairment resulting from chronic restraint stress in ovariectomized mice. Journal of pharmacological sciences. vol 120. issue 2. 2013-03-12. PMID:22971911. |
placental extract improves hippocampal neuronal loss and fear memory impairment resulting from chronic restraint stress in ovariectomized mice. |
2013-03-12 |
2023-08-12 |
mouse |
| Markus Krieger, Martin Both, Simon A Kranig, Claudia Pitzer, Matthias Klugmann, Gerhard Vogt, Andreas Draguhn, Armin Schneide. The hematopoietic cytokine granulocyte-macrophage colony stimulating factor is important for cognitive functions. Scientific reports. vol 2. 2013-02-15. PMID:23019518. |
gm-csf ablation caused various hippocampus and amygdala-dependent deficits in spatial and fear memory while rendering intact basic parameters like motor function, inherent anxiety, and pain threshold levels. |
2013-02-15 |
2023-08-12 |
mouse |