| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing-Bo He, He Zhang, Hong-Xia Zheng, Jian-Xin Jia, Yi-Chi Zhang, Xu-Sheng Yan, Xiao-Xu Li, Kai-Wen Wei, Jun Mao, Hong Chen, Jing Li, He Wang, Ming Zhang, Zhi-Ying Zha. Effects of schisandrin B on hypoxia-related cognitive function and protein expression in vascular dementia rats. Journal of toxicology and environmental health. Part A. 2024-03-29. PMID:38551405. |
the results showed that sch b improved learning and memory function of rats with vd and exerted a protective effect on the hippocampus by inhibition of protein expression of hif-1α, trak2, and hummr factors. |
2024-03-29 |
2024-03-31 |
rat |
| Yunlin Feng, Jia Qin, Yanfei Lu, Mengdie Wang, Shengqiang Wang, Foquan Lu. Suberoylanilide hydroxamic acid attenuates cognitive impairment in offspring caused by maternal surgery during mid-pregnancy. PloS one. vol 19. issue 3. 2024-03-29. PMID:38551911. |
our results showed that maternal propofol exposure during middle pregnancy impaired the water-maze learning and memory of the offspring rats, increased the protein level of hdac2 and reduced the protein levels of p-creb, bdnf and p-trkb in the hippocampus of the offspring, and such effects were exacerbated by surgery. |
2024-03-29 |
2024-04-01 |
rat |
| Kushagra Nagori, Madhulika Pradhan, Mukesh Sharma, Ajazuddin, Hemant R Badwaik, Kartik T Nakhat. Current Progress on Central Cholinergic Receptors as Therapeutic Targets for Alzheimer's Disease. Current Alzheimer research. 2024-03-26. PMID:38529600. |
by modulating synaptic transmission and promoting synaptic plasticity, particularly in the hippocampus and cortex, ach plays a pivotal role in the regulation of learning and memory. |
2024-03-26 |
2024-03-28 |
Not clear |
| Zhiyuan Wang, Bin Han, Jianjiao Qi, Xuelei Cao, Huali Gu, Jinping Su. Chuanzhitongluo capsule improves cognitive impairment in mice with chronic cerebral hypoperfusion via the cholinergic anti-inflammatory pathway. Experimental gerontology. vol 189. 2024-03-24. PMID:38522309. |
results indicated that cztl significantly improved the spatial learning and memory abilities of cch mice, along with alterations in gene expression profiles in the hippocampus. |
2024-03-24 |
2024-03-27 |
mouse |
| Tegan A White, Suzanne L Miller, Amy E Sutherland, Beth J Allison, Emily J Cam. Perinatal compromise affects development, form, and function of the hippocampus part one; clinical studies. Pediatric research. 2024-03-23. PMID:38519794. |
the hippocampus is a neuron-rich specialised brain structure that plays a central role in the regulation of emotions, learning and memory, cognition, spatial navigation, and motivational processes. |
2024-03-23 |
2024-03-26 |
human |
| Vaibhav Gupta, Rashmi Srivastav. Ashwagandha Diminishes Hippocampal Apoptosis Induced by Microwave Radiation by Acetylcholinesterase Dependent Neuro-Inflammatory Pathway in Male Coturnix coturnix Japonica. Neurochemical research. 2024-03-20. PMID:38506951. |
microwave radiation (mwr) has been linked to neurodegeneration by inducing oxidative stress in the hippocampus of brain responsible for learning and memory. |
2024-03-20 |
2024-03-23 |
cat |
| Jiaxiang Wu, Jingliang Zhang, Xiaoling Chen, Kyle Wettschurack, Zhefu Que, Brody A Deming, Maria I Olivero-Acosta, Ningren Cui, Muriel Eaton, Yuanrui Zhao, Sophia M Li, Matthew Suzuki, Ian Chen, Tiange Xiao, Manasi S Halurkar, Purba Mandal, Chongli Yuan, Ranjie Xu, Wendy A Koss, Dongshu Du, Fuxue Chen, Long-Jun Wu, Yang Yan. Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids. Molecular psychiatry. 2024-03-19. PMID:38499656. |
here, we reported that scn2a-deficient mice have impaired learning and memory, accompanied by reduced synaptic transmission and lower spine density in neurons of the hippocampus. |
2024-03-19 |
2024-03-21 |
mouse |
| Haoxuan Gao, Mi Tian, Xiaozhe Geng, Ji Zhao, Yanan Song, Bing Wu, Xueyan Tian, Yong Yang, Wensi Ni, Huifang Yan. Cyfluthrin exposure during pregnancy causes neurotoxicity in offspring-Ca Ecotoxicology and environmental safety. vol 274. 2024-03-16. PMID:38492481. |
we found that gestational cy exposure affected pregnancy outcomes and fetal development, and that offspring showed impairments in anxiety as well as learning and memory, accompanied by impairments in hippocampal synaptic ultrastructure and synaptic plasticity. |
2024-03-16 |
2024-03-19 |
Not clear |
| Yukitoshi Izumi, Kazuko A O'Dell, Charles F Zorumsk. Glyphosate as a direct or indirect activator of pro-inflammatory signaling and cognitive impairment. Neural regeneration research. vol 19. issue 10. 2024-03-15. PMID:38488555. |
we recently found that a single injection of glyphosate inhibits long-term potentiation, a cellular model of learning and memory, in rat hippocampal slices dissected 1 day after injection, indicating that glyphosate-based herbicides can alter cognitive function. |
2024-03-15 |
2024-03-17 |
rat |
| Huiping Wu, Na Li, Shuang Peng, Haiyan Fu, Zhansheng Hu, Longxiang S. Maresin1 improves hippocampal neuroinflammation and cognitive function in septic rats by activating the SLC7A11 / GPX4 ferroptosis signaling pathway. International immunopharmacology. vol 131. 2024-03-14. PMID:38484667. |
we evaluated rat learning and memory using a water maze, assessed hippocampal neuron damage via nissl and fjc staining, and observed mitochondrial alterations through tem. |
2024-03-14 |
2024-03-17 |
rat |
| Jianxiong Gui, Mingdan Xie, Lingman Wang, Bing Tian, Benke Liu, Hengsheng Chen, Li Cheng, Dishu Huang, Ziyao Han, Xiaoyue Yang, Jie Liu, Li Jian. Protective effects of docosahexaenoic acid supplementation on cognitive dysfunction and hippocampal synaptic plasticity impairment induced by early postnatal PM2.5 exposure in young rats. Naunyn-Schmiedeberg's archives of pharmacology. 2024-03-09. PMID:38459987. |
dha could ameliorate pm2.5-induced learning and memory dysfunction, as well as reverse the impairment of hippocampal synaptic plasticity, evidenced by enhanced long-term potentiation, recovered synaptic ultrastructure, and increased expression of synaptic proteins. |
2024-03-09 |
2024-03-12 |
rat |
| Shunta Goto, Natsuki Kojima, Miyu Komori, Noe Kawade, Kenzi Oshima, Daita Nadano, Nobumitsu Sasaki, Fumihiko Horio, Tsukasa Matsuda, Shinji Miyat. Vitamin C deficiency alters the transcriptome of the rat brain in a glucocorticoid-dependent manner, leading to microglial activation and reduced neurogenesis. The Journal of nutritional biochemistry. 2024-03-08. PMID:38458474. |
furthermore, vitc deficiency decreased the number of newly born neurons in the dentate gyrus of the hippocampus, suggesting that vitc was required for adult neurogenesis that plays a crucial role in learning and memory. |
2024-03-08 |
2024-03-11 |
rat |
| Makoto Katsube, Takahiro Ishimoto, Yutaro Fukushima, Asuka Kagami, Tsuyoshi Shuto, Yukio Kat. Ergothioneine promotes longevity and healthy aging in male mice. GeroScience. 2024-03-06. PMID:38446314. |
the oral intake of ergo also rescued age-related impairments in learning and memory ability, which might be associated with suppression of the age-related decline in hippocampal neurogenesis and tdp43 protein aggregation and promotion of microglial shift to the m2 phenotype by ergo ingestion. |
2024-03-06 |
2024-03-08 |
mouse |
| Elias A Samona, Asadur Chowdury, John Kopchick, Patricia Thomas, Usha Rajan, Dalal Khatib, Caroline Zajac-Benitez, Alireza Amirsadri, Luay Haddad, Jeffrey A Stanley, Vaibhav A Diwadka. The importance of covert memory consolidation in schizophrenia: Dysfunctional network profiles of the hippocampus and the dorsolateral prefrontal cortex. Psychiatry research. Neuroimaging. vol 340. 2024-03-06. PMID:38447230. |
here, we compared network signatures of the dlpfc and the hippocampus during covert periods of a learning and memory task. |
2024-03-06 |
2024-03-09 |
Not clear |
| Daymara Mercerón-Martínez, Laura Alacán Ricardo, Arturo Bejerano Pina, Norma Orama Rojo, Ariel Expósito Seco, Yamilé Vega Hurtado, Bárbara Estupiñán Días, Isabel Fernández, Laura García Pupo, Marquiza Sablón Carrazana, Chryslaine Rodríguez-Tanty, Roberto Menéndez Soto Del Valle, William Almaguer-Melia. Amylovis-201 enhances physiological memory formation and rescues memory and hippocampal cell loss in a streptozotocin-induced Alzheimer's disease animal model. Brain research. 2024-03-03. PMID:38432261. |
in the first and third experiment, animals received a bilateral administration of streptozotocin and, starting 24 h after injection, a daily dose of amylovis-201 (orally), for 17 days or for the whole time of the experiment respectively (28 days), after which learning and memory, as well as the number of hippocampal dentate gyrus cells, were assessed. |
2024-03-03 |
2024-03-06 |
Not clear |
| Yuchen Li, Sisi Luan, Cairong Ruan, Weihao Li, Xinyu Zhang, Zijing Ran, Wenkai Bi, Yuelin Tong, Ling Gao, Jiajun Zhao, Yuan Li, Zhao H. TSHR signaling promotes hippocampal dependent memory formation through modulating Wnt5a/β-catenin mediated neurogenesis. Biochemical and biophysical research communications. vol 704. 2024-03-02. PMID:38430698. |
in this study, we found that tshr-deficient in the hippocampal neurons impairs the learning and memory abilities of mice, accompanying by a decline in the number of newborn neurons. |
2024-03-02 |
2024-03-06 |
mouse |
| Paromita Das-Earl, Derek A Schreihofer, Nathalie Sumien, Ann M Schreihofe. Temporal and region-specific tau hyperphosphorylation in the medulla and forebrain coincides with development of functional changes in male obese Zucker rats. Journal of neurophysiology. 2024-02-28. PMID:38416718. |
in addition to regulating energy balance, leptin enhances activation of the hippocampus, which is essential for spatial learning and memory. |
2024-02-28 |
2024-03-02 |
rat |
| Fang Zhao, Chuhan Li, Yinghan Zhuang, Yan Yan, Yanqin Gao, Thomas Behnisc. Apoptosis signal-regulating kinase 1 ( Frontiers in cellular neuroscience. vol 18. 2024-02-28. PMID:38414754. |
a possible explanation for their manifestation is a disturbed pattern of dopamine release in brain regions involved in learning and memory, such as the hippocampus. |
2024-02-28 |
2024-03-01 |
Not clear |
| Dingding Lv, Bin Xiao, Huaying Liu, Linping Wang, Yingshun Li, Yin Hua Zhang, Qinghua Ji. Enhanced NMDA receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats. Pflugers Archiv : European journal of physiology. 2024-02-28. PMID:38416255. |
enhanced nmda receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats. |
2024-02-28 |
2024-03-01 |
rat |
| Dingding Lv, Bin Xiao, Huaying Liu, Linping Wang, Yingshun Li, Yin Hua Zhang, Qinghua Ji. Enhanced NMDA receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats. Pflugers Archiv : European journal of physiology. 2024-02-28. PMID:38416255. |
since glutamatergic transmission and nmda receptor neural pathways in hippocampal dentate gyrus (dg) are essential in the learning and memory, we aimed to investigate glutamate (glu) and nmda receptor signaling of dg in spatial learning and memory in diet-induced obesity (dio) rats. |
2024-02-28 |
2024-03-01 |
rat |