| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Z G Xia, C D Refsdal, K M Merchant, D M Dorsa, D R Stor. Distribution of mRNA for the calmodulin-sensitive adenylate cyclase in rat brain: expression in areas associated with learning and memory. Neuron. vol 6. issue 3. 1991-04-16. PMID:2001286. |
mrna for this enzyme is expressed in specific areas of brain that have been implicated in learning and memory, including the neocortex, the hippocampus, and the olfactory system. |
1991-04-16 |
2023-08-11 |
rat |
| T Kitajima, K Har. A model of the mechanisms of long-term potentiation in the hippocampus. Biological cybernetics. vol 64. issue 1. 1991-03-22. PMID:2149518. |
long-term potentiation (ltp) in the hippocampus has been considered to be a phenomenon closely related to learning and memory in the brain. |
1991-03-22 |
2023-08-11 |
Not clear |
| R F Thompso. Neural mechanisms of classical conditioning in mammals. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 329. issue 1253. 1990-12-12. PMID:1978361. |
although it plays a role in certain aspects of conditioning, the hippocampus is not necessary for learning and memory of the basic conditioned responses. |
1990-12-12 |
2023-08-11 |
Not clear |
| G Winocur, M Moscovitc. Hippocampal and prefrontal cortex contributions to learning and memory: analysis of lesion and aging effects on maze learning in rats. Behavioral neuroscience. vol 104. issue 4. 1990-11-19. PMID:2206425. |
hippocampal and prefrontal cortex contributions to learning and memory: analysis of lesion and aging effects on maze learning in rats. |
1990-11-19 |
2023-08-11 |
rat |
| Y Ben-Ari, A Repres. Brief seizure episodes induce long-term potentiation and mossy fibre sprouting in the hippocampus. Trends in neurosciences. vol 13. issue 8. 1990-11-01. PMID:1699312. |
much of our present understanding of the cellular mechanisms of learning and memory derives from studies on the hippocampus in which long-term potentiation (ltp) of synaptic transmission is produced by a train of high-frequency electrical stimulation or by potassium channel blockers. |
1990-11-01 |
2023-08-11 |
Not clear |
| H J Altman, H J Normile, M P Galloway, A Ramirez, E C Azmiti. Enhanced spatial discrimination learning in rats following 5,7-DHT-induced serotonergic deafferentation of the hippocampus. Brain research. vol 518. issue 1-2. 1990-10-04. PMID:1697213. |
the present results provide, therefore, evidence in support of a neuromodulatory role for serotonin (5-ht) within the rat hippocampus in the mediation of the processes underlying learning and memory for this task. |
1990-10-04 |
2023-08-11 |
rat |
| H J Altman, H J Normile, M P Galloway, A Ramirez, E C Azmiti. Enhanced spatial discrimination learning in rats following 5,7-DHT-induced serotonergic deafferentation of the hippocampus. Brain research. vol 518. issue 1-2. 1990-10-04. PMID:1697213. |
other studies are, therefore, warranted in order to determine whether hippocampal 5-ht also plays a role in the mediation of the processes underlying learning and memory in other types of tasks. |
1990-10-04 |
2023-08-11 |
rat |
| P Monmaur, M Allix, D Schoëvaërt-Brossault, O Houcine, M Plotkine, F Willi. Effects of transient cerebral ischemia on the hippocampal dentate theta (theta) profile in the acute rat: a study 4-5 months following recirculation. Brain research. vol 508. issue 1. 1990-06-20. PMID:2337781. |
possible significance of these findings for the hypothesis of the dependent generation sites of superficial and deep thetas in the hippocampus assumed to be crucial in learning and memory, is discussed. |
1990-06-20 |
2023-08-11 |
rat |
| K L McDaniel, W R Mundy, H A Tilso. Microinjection of dynorphin into the hippocampus impairs spatial learning in rats. Pharmacology, biochemistry, and behavior. vol 35. issue 2. 1990-05-03. PMID:1969641. |
the effect of hippocampal dynorphin administration on learning and memory was examined in spatial and nonspatial tasks. |
1990-05-03 |
2023-08-11 |
rat |
| K L McDaniel, W R Mundy, H A Tilso. Microinjection of dynorphin into the hippocampus impairs spatial learning in rats. Pharmacology, biochemistry, and behavior. vol 35. issue 2. 1990-05-03. PMID:1969641. |
these results suggest that dynorphin specifically interferes with spatial learning and memory, and that this effect is mediated by opioid receptors in the dorsal hippocampus. |
1990-05-03 |
2023-08-11 |
rat |
| M P Mattson, P B Guthrie, S B Kate. Intrinsic factors in the selective vulnerability of hippocampal pyramidal neurons. Progress in clinical and biological research. vol 317. 1990-01-31. PMID:2690106. |
several lines of evidence suggest that glutamate, an excitatory neurotransmitter intimately involved in learning and memory processes, may also be involved in hippocampal neurodegeneration. |
1990-01-31 |
2023-08-11 |
rat |
| M P Mattson, P B Guthrie, S B Kate. Intrinsic factors in the selective vulnerability of hippocampal pyramidal neurons. Progress in clinical and biological research. vol 317. 1990-01-31. PMID:2690106. |
treatments which block glutamate receptors, suppress electrical activity, or block calcium channels directly may prove useful in preventing the degeneration of the hippocampal circuitry whose integrity is critical for learning and memory processes. |
1990-01-31 |
2023-08-11 |
rat |
| J T Greenamyre, A B Youn. Excitatory amino acids and Alzheimer's disease. Neurobiology of aging. vol 10. issue 5. 1989-12-18. PMID:2554168. |
excitatory amino acids (eaa) such as glutamate and aspartate are major transmitters of the cerebral cortex and hippocampus, and eaa mechanisms appear to play a role in learning and memory. |
1989-12-18 |
2023-08-11 |
Not clear |
| B C Rogers, M I Barnes, C L Mitchell, H A Tilso. Functional deficits after sustained stimulation of the perforant path. Brain research. vol 493. issue 1. 1989-10-25. PMID:2776009. |
the learning and memory deficits were associated with a loss of ca1 and ca3 pyramidal cells and pretreatment with the n-methyl-d-aspartate antagonist mk-801 reduced this cell loss, particularly in the ca1 region of the hippocampus. |
1989-10-25 |
2023-08-11 |
Not clear |
| J Sif, M Meunier, C Messier, A Calas, C Destrad. Quantitative [14C]2-deoxyglucose study of a functional dissociation between anterior and posterior cingulate cortices in mice. Neuroscience letters. vol 101. issue 2. 1989-10-12. PMID:2771167. |
this result is consistent with the hypothesis that learning and memory deficits following ccp lesion may be due to the disruption of functional neural pathways between the ccp and hippocampal structures. |
1989-10-12 |
2023-08-11 |
mouse |
| K Ishihara, H Katsuki, M Sugimura, M Sato. Idebenone and vinpocetine augment long-term potentiation in hippocampal slices in the guinea pig. Neuropharmacology. vol 28. issue 6. 1989-08-29. PMID:2569175. |
the effects of idebenone and vinpocetine which reportedly prevent impairment of learning and memory were studied in vitro, on the long-term potentiation of the population spike in the pyramidal layer of ca3 region of slices of hippocampus in the guinea pig. |
1989-08-29 |
2023-08-11 |
Not clear |
| O Ghirardi, S Milano, M T Ramacci, L Angelucc. Effect of acetyl-l-carnitine chronic treatment on discrimination models in aged rats. Physiology & behavior. vol 44. issue 6. 1989-07-12. PMID:3249750. |
because impaired learning and memory are related to alterations in hippocampal function, these data indicate that alc is capable of antagonizing the natural age-dependent deterioration process in the hippocampal structure. |
1989-07-12 |
2023-08-11 |
rat |
| S N Davies, R A Lester, K G Reymann, G L Collingridg. Temporally distinct pre- and post-synaptic mechanisms maintain long-term potentiation. Nature. vol 338. issue 6215. 1989-05-05. PMID:2564640. |
long-term potentiation (ltp) in the hippocampus is widely studied as the mechanisms involved in its induction and maintenance are believed to underlie fundamental properties of learning and memory in vertebrates. |
1989-05-05 |
2023-08-11 |
Not clear |
| N A Muma, P P Rowel. Effects of chronic choline and lecithin on mouse hippocampal dendritic spine density. Experimental aging research. vol 14. issue 2-3. 1989-05-04. PMID:3234454. |
the results indicate that dietary supplementation may have different effects in different brain areas and that the relative increase in learning and memory function in aged animals given a choline or lecithin enriched diet is not due to an increase in hippocampal dendritic spine density. |
1989-05-04 |
2023-08-11 |
mouse |
| N Popov, S Schulzeck, D Nüss, A U Vopel, C Jendrny, H Struy, H Matthie. Alterations in calmodulin content of rat brain areas after chronic application of haloperidol and amphetamine. Biomedica biochimica acta. vol 47. issue 4-5. 1989-04-25. PMID:3240294. |
the hippocampus, the region poor in dopamine while playing an essential role in learning and memory formation processes, revealed similar patterns after both modes of treatment. |
1989-04-25 |
2023-08-11 |
rat |