| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carlos A Lafourcade, Fraser T Sparks, Angelique Bordey, Ursula Wyneken, Michael H Mohammad. Cannabinoid regulation of neurons in the dentate gyrus during epileptogenesis. Role of CB1R-associated proteins and downstream pathways. Epilepsia vol issue 2023 36869624 |
acting as a filter or gate, the hippocampal dentate gyrus (dg) normally prevents excessive excitation from propagating through the hippocampus, and is considered a critical region in the progression of epileptogenesis in pathological conditions. |
2023-03-04 |
2023-03-06 |
Not clear |
| Alicia Comino Garcia-Munoz, Yasser Alem\\xc3\\xa1n-G\\xc3\\xb3mez, Rafael Toledano, Claudia Poch, Irene Garc\\xc3\\xada-Morales, \\xc3\\x81ngel Aledo-Serrano, Antonio Gil-Nagel, Pablo Camp. Morphometric and microstructural characteristics of hippocampal subfields in mesial temporal lobe epilepsy and their correlates with mnemonic discrimination. Frontiers in neurology vol 14 issue 2023 36864916 |
experimental evidence in animal models and the study of other human pathologies have demonstrated the role of the hippocampus in ps, in particular of the dentate gyrus (dg) and ca3. |
2023-03-03 |
2023-03-06 |
human |
| Zo\\xc3\\xa9 Christenson Wick, Paul A Philipsberg, Sophia I Lamsifer, Cassidy Kohler, Elizabeth Katanov, Yu Feng, Corin Humphrey, Tristan Shuma. Manipulating single-unit theta phase-locking with PhaSER: An open-source tool for real-time phase estimation and manipulation. bioRxiv : the preprint server for biology vol issue 2023 36865324 |
here, we describe and validate this tool in a subpopulation of inhibitory neurons that express somatostatin (som) in the ca1 and dentate gyrus (dg) regions of the dorsal hippocampus. |
2023-03-03 |
2023-03-06 |
mouse |
| M Omidi-Shahsavandi, P Yaghmaei, S Ahmadian, A Ebrahim-Habib. Effect of silibinin and trans-chalcone in an Alzheimer's disease-like model generated by insulin amyloids. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas vol 56 issue 2023 36856252 |
histological investigation of the hippocampus in the cornu ammonis (ca1) and dentate gyrus (dg) regions of the rat's brain stained with hematoxylin-eosin and thioflavin s showed an inhibitory effect on amyloid aggregation and markedly reduced amyloid plaques. |
2023-03-01 |
2023-03-06 |
rat |
| Takahiro Fuchigami, Yutaka Itokazu, John C Morgan, Robert K Y. Restoration of Adult Neurogenesis by Intranasal Administration of Gangliosides GD3 and GM1 in The Olfactory Bulb of A53T Alpha-Synuclein-Expressing Parkinson's-Disease Model Mice. Molecular neurobiology vol issue 2023 36849668 |
we have reported that ganglioside gd3 is required to maintain the neural stem cell (nsc) pool in the subventricular zone (svz) of the lateral ventricles and the subgranular layer of the dentate gyrus (dg) in the hippocampus. |
2023-02-28 |
2023-03-06 |
mouse |
| Nat\\xc3\\xa1lia Ferreira Silva, Fernanda Naves Ara\\xc3\\xbajo do Prado Mascarenhas, Daniele Lisboa Ribeiro, Renata Graciele Zano. Alterations in the dentate gyrus of the offspring of rats treated with alprazolam during gestation. Journal of chemical neuroanatomy vol issue 2023 36841439 |
for this population, the drug of choice is usually alprazolam, which acts as a gabaergic agonist and may compromise the development of integrative areas of the nervous system, such as the dentate gyrus (dg) of the hippocampus. |
2023-02-25 |
2023-03-06 |
rat |
| Nat\\xc3\\xa1lia Ferreira Silva, Fernanda Naves Ara\\xc3\\xbajo do Prado Mascarenhas, Daniele Lisboa Ribeiro, Renata Graciele Zano. Alterations in the dentate gyrus of the offspring of rats treated with alprazolam during gestation. Journal of chemical neuroanatomy vol issue 2023 36841439 |
the newborns' brains were extracted and processed for morphological study of the dg or for total protein extraction of the hippocampus. |
2023-02-25 |
2023-03-06 |
rat |
| K Wilmerding Lucius, Kondratyev Ivan, Ramire Steve, E Hasselm Michae. Route-dependent spatial engram tagging in mouse dentate gyrus. Neurobiology of learning and memory vol issue 2023 36822466 |
the dentate gyrus (dg) of hippocampus is hypothesized to act as a pattern separator that distinguishes between similar input patterns during memory formation and retrieval. |
2023-02-23 |
2023-03-06 |
mouse |
| Xiaosheng Liang, Zhuming Xue, Yangwu Zheng, Shufang Li, Lijun Zhou, Lin Cao, Yi Zo. Selenium supplementation enhanced the expression of selenoproteins in hippocampus and played a neuroprotective role in LPS-induced neuroinflammation. International journal of biological macromolecules vol issue 2023 36806773 |
the selenop expression in the mediodorsal thalamic nucleus, dendric gyrus (dg) and cornu ammonis 3 (ca3) of hippocampus and lateral habenular nucleus was highly sensitive to dietary se intake. |
2023-02-22 |
2023-03-06 |
mouse |
| Yu Qu, Nan Zhou, Xia Zhang, Yan Li, Xu-Feng X. Chromatin Remodeling Factor SMARCA5 is Essential for Hippocampal Memory Maintenance via Metabolic Pathways in Mice. Neuroscience bulletin vol issue 2023 36807260 |
using proteomics analysis, we found protein expression changes in the hippocampal dentate gyrus (dg) after the knockdown of smarca5 during contextual fear conditioning (cfc) memory maintenance in mice. |
2023-02-22 |
2023-03-06 |
mouse |
| Sarah L Parylak, Fan Qiu, Sara B Linker, Iryna S Gallina, Christina K Lim, David Preciado, Aidan H McDonald, Xavier Zhou, Fred H Gag. Neuronal activity-related transcription is blunted in immature compared to mature dentate granule cells. Hippocampus vol issue 2023 36811254 |
immature dentate granule cells (dgcs) generated in the hippocampus during adulthood are believed to play a unique role in dentate gyrus (dg) function. |
2023-02-22 |
2023-03-06 |
mouse |
| Kimberly L P Long, Sandra E Muroy, Siamak K Sorooshyari, Mee Jung Ko, Yanabah Jaques, Peter Sudmant, Daniela Kaufe. Transcriptomic profiles of stress susceptibility and resilience in the amygdala and hippocampus. bioRxiv : the preprint server for biology vol issue 2023 36798395 |
the dentate gyrus (dg) of the hippocampus and the basolateral nucleus of the amygdala (bla) are key limbic regions that are susceptible to the neural and hormonal effects of stress. |
2023-02-17 |
2023-03-06 |
rat |
| Anita Lewczuk, Anna Boraty\\xc5\\x84ska-Jasi\\xc5\\x84ska, Barbara Zab\\xc5\\x82ock. Validation of the Reference Genes for Expression Analysis in the Hippocampus after Transient Ischemia/Reperfusion Injury in Gerbil Brain. International journal of molecular sciences vol 24 issue 3 2023 36769080 |
in cornu ammonnis 2-3, dentate gyrus (ca2-3,dg) regions of the hippocampus, neurons are resistant to 5-min ischemia/reperfusion (i/r) insult, while cornu ammonnis 1 (ca1) is found to be i/r-vulnerable. |
2023-02-11 |
2023-03-06 |
Not clear |
| Yongjie Zhou, Xiaoxiao Zou, Ruifang Feng, Xin Zhan, Hui Hong, Yongkang Luo, Yuqing Ta. Improvement of Spatial Memory and Cognitive Function in Mice via the Intervention of Milk Fat Globule Membrane. Nutrients vol 15 issue 3 2023 36771241 |
also, the immunohistochemical results demonstrated a significantly higher number of neurons in group m compared with group c, especially in the hippocampal dentate gyrus (dg) area. |
2023-02-11 |
2023-03-06 |
mouse |
| Ramin Abdi Dezfouli, Sajad Mazaheri, Zahra Mousavi, Abbas Haghparas. Restraint stress induced the antinociceptive responses via the dopamine receptors within the hippocampal CA1 area in animal model of persistent inflammatory pain. Behavioural brain research vol 443 issue 2023 36764008 |
a prior study showed that dopamine receptors within the hippocampal dg have a critical role in antinociception induced by forced swim stress (fss), as a physical stressor, in the presence of formalin irritation. |
2023-02-10 |
2023-03-06 |
rat |
| Sanghee Yun, Ivan Soler, Fionya Tran, Harley A Haas, Raymon Shi, Grace L Bancroft, Maiko Suarez, Chris R de Santis, Ryan P Reynolds, Amelia J Eisc. Behavioral pattern separation and cognitive flexibility are enhanced in a mouse model of increased lateral entorhinal cortex-dentate gyrus circuit activity. bioRxiv : the preprint server for biology vol issue 2023 36747871 |
in humans and mice, discrimination and adaptation rely on integrity of the hippocampal dentate gyrus (dg) which both receive glutamatergic input from the entorhinal cortex (ec), including the lateral ec (lec). |
2023-02-07 |
2023-03-06 |
mouse |
| Annalisa Adinolfi, Gabriele Di Sante, Luca Rivignani Vaccari, Maria Tredicine, Francesco Ria, Davide Bonvissuto, Valentina Corvino, Claudio Sette, Maria Concetta Gelos. Regionally restricted modulation of Frontiers in molecular neuroscience vol 15 issue 2023 36710925 |
in this study, we investigated several parameters of neuroplasticity in the hippocampus of the experimental autoimmune encephalomyelitis (eae) sjl/j mouse model, characterized by rostral inflammatory and demyelinating lesions similar to relapsing-remitting ms. by combining morphological and molecular analyses, we found that the hippocampus undergoes extensive inflammation in eae-mice, more pronounced in the ca3 and dentate gyrus (dg) subfields than in the ca1, associated with changes in gabaergic circuitry, as indicated by the increased expression of the interneuron marker parvalbumin selectively in ca3. |
2023-01-30 |
2023-01-31 |
mouse |
| Ran Zhang, Meixuan Chen, Zhongfang Deng, Lingchao Kong, Bing Shen, Lesha Zhan. Delta Opioid Peptide Targets Brain Microvascular Endothelial Cells Reducing Apoptosis to Relieve Hypoxia-Ischemic/Reperfusion Injury. Pharmaceutics vol 15 issue 1 2023 36678674 |
the co-localization results showed that bmecs, but not astrocytes, microglia, or neurons, presented mostly tunel-positive signals, especially in the dentate gyrus (dg) area of the hippocampus. |
2023-01-21 |
2023-01-30 |
rat |
| Shi-Hao Wu, Xiao Li, Dong-Dong Qin, Lin-Heng Zhang, Tian-Lin Cheng, Zhi-Fang Chen, Bin-Bin Nie, Xiao-Feng Ren, Jing Wu, Wen-Chao Wang, Ying-Zhou Hu, Yi-Lin Gu, Long-Bao Lv, Yong Yin, Xin-Tian Hu, Zi-Long Qi. Induction of core symptoms of autism spectrum disorder by in vivo CRISPR/Cas9-based gene editing in the brain of adolescent rhesus monkeys. Science bulletin vol 66 issue 9 2023 36654241 |
here we induced genetic mutations in mecp2, a critical gene linked to rett syndrome (rtt) and autism spectrum disorders (asd), in the hippocampus (dg and ca1-4) of adolescent rhesus monkeys (macaca mulatta) in vivo via adeno-associated virus (aav)-delivered staphylococcus aureus cas9 with small guide rnas (sgrnas) targeting mecp2. |
2023-01-19 |
2023-01-30 |
human |
| Yunyun Li, Xiaodie Liu, Qianqian Fu, Wenxiang Fan, Xiaomei Shao, Jianqiao Fang, Jing-Gen Liu, Chi X. Electroacupuncture ameliorates depression-like behaviors comorbid to chronic neuropathic pain via Tet1-mediated restoration of adult neurogenesis. Stem cells (Dayton, Ohio) vol issue 2023 36648299 |
thus, we conclude that ea stimulation restores inhibited tet1 expression in hippocampal nscs of mice with chronic neuropathic pain, and increased tet1 expression ameliorates hypermethylation of prox1 and restores normal adult neurogenesis in the ventral dg, which contributes to the long-term antidepressant effect of ea. |
2023-01-17 |
2023-01-30 |
mouse |