All Relations between hippocampus and medial prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
Mingzhu Hou, Marianne de Chastelaine, Michael D Rug. The effects of age on neural correlates of recollection: transient versus sustained fMRI effects. bioRxiv : the preprint server for biology. 2023-04-24. PMID:37090506. replicating prior findings, transient recollection effects were identified in the left hippocampus, medial prefrontal cortex and posterior cingulate, while sustained effects were widespread across left lateral cortex and were also evident in the bilateral striatum. 2023-04-24 2023-08-14 human
B M Romero-Torres, Y A Alvarado-Ramírez, S R Duran-Alonzo, A E Ruiz-Contreras, A Herrera-Solis, O Amancio-Belmont, O E Prospéro-García, M Méndez-Día. A potential role of hippocampus on impulsivity and alcohol consumption though CB1R. Pharmacology, biochemistry, and behavior. 2023-04-23. PMID:37088449. to further understand the potential role of the hippocampal cb1r in impulsive and drug seeking behaviors, we characterized impulsivity in adolescent and adult male rats, by means of a delay discounting task (ddt) by evaluating preference and seeking motivation for alcohol (10 % v/v) consumption, and analyzing cb1r expression in ca1, ca3 and the dentate gyrus (dg) of the hpp as well as in the medial prefrontal cortex (mpfc). 2023-04-23 2023-08-14 rat
Sara Arciniegas Ruiz, Eliav Tikochinsky, Vardit Rubovitch, Chaim G Pick, Bernard Attal. Contextual fear response is modulated by M-type K+ channels and is associated with subtle structural changes of the axon initial segment in hippocampal GABAergic neurons. AIMS neuroscience. vol 10. issue 1. 2023-04-20. PMID:37077956. in the fear memory network, the hippocampus modulates contextual aspects of fear learning while mutual connections between the amygdala and the medial prefrontal cortex are widely involved in fear extinction. 2023-04-20 2023-08-14 mouse
Cristina Delgado-Sallent, Thomas Gener, Pau Nebot, Cristina López-Cabezón, M Victoria Pui. Neural substrates of cognitive impairment in a NMDAR hypofunction mouse model of schizophrenia and partial rescue by risperidone. Frontiers in cellular neuroscience. vol 17. 2023-04-17. PMID:37066076. we recorded neural activities in the medial prefrontal cortex (mpfc) and the dorsal hippocampus (dhpc) during memory acquisition, short-term, and long-term memory in the novel object recognition test and during auditory processing and mismatch negativity (mmn) and examined the effects of spcp and spcp followed by risperidone. 2023-04-17 2023-08-14 mouse
Wei-Yu Li, Tian-Shun Shi, Jie Huang, Yan-Mei Chen, Wei Guan, Bo Jiang, Cheng-Niu Wan. Activation of the mTORC1 signaling cascade in the hippocampus and medial prefrontal cortex is required for the antidepressant actions of vortioxetine in mice. The international journal of neuropsychopharmacology. 2023-04-07. PMID:37025079. activation of the mtorc1 signaling cascade in the hippocampus and medial prefrontal cortex is required for the antidepressant actions of vortioxetine in mice. 2023-04-07 2023-08-14 mouse
L van Drunen, Y J Toenders, L M Wierenga, E A Cron. Effects of COVID-19 pandemic on structural brain development in early adolescence. Scientific reports. vol 13. issue 1. 2023-04-05. PMID:37019914. we investigated structural changes in social brain regions (medial prefrontal cortex: mpfc; temporoparietal junction: tpj) as well as the stress-related hippocampus and amygdala, using a longitudinal design of 2 mri waves. 2023-04-05 2023-08-14 Not clear
Brandon Emanuel León, Lee Peyton, Hesham Essa, Tia Wieden, Nicole Marion, Wayne E Childers, Magid Abou-Gharbia, Doo-Sup Cho. A novel monobactam lacking antimicrobial activity, MC-100093, reduces sex-specific ethanol preference and depressive-like behaviors in mice. Neuropharmacology. 2023-03-31. PMID:37001726. western blot analysis of the medial prefrontal cortex and hippocampus revealed no changes in male or female glt1 protein abundance relative to gapdh. 2023-03-31 2023-08-14 mouse
P Abad-Perez, Molina-Payá F J, L Martínez-Otero, V Borrell, R L Redondo, J R Brotons-Ma. Theta/gamma co-modulation disruption after nmdar blockade by mk801 is associated with spatial working memory deficits in mice. Neuroscience. 2023-03-29. PMID:36990270. we implanted mice with tetrodes in the dorsal/intermediate hippocampus and medial prefrontal cortex (mpfc), administered the nmdar antagonist mk-801, and recorded oscillations during spontaneous exploration in an open field and in the y-maze spatial working memory test. 2023-03-29 2023-08-14 mouse
Sijie Tan, Wen Han Tong, Ajai Vya. Impaired episodic-like memory in a mouse model of Alzheimer's disease is associated with hyperactivity in prefrontal-hippocampal regions. Disease models & mechanisms. vol 16. issue 3. 2023-03-10. PMID:36897115. c-fos expression revealed that impaired memory retrieval in appnl-g-f mice was accompanied by abnormal neuronal hyperactivity in the medial prefrontal cortex and ca1 dorsal hippocampus. 2023-03-10 2023-08-14 mouse
Zachariah M Reagh, Charan Ranganat. Flexible reuse of cortico-hippocampal representations during encoding and recall of naturalistic events. Nature communications. vol 14. issue 1. 2023-03-08. PMID:36890146. medial prefrontal cortex generalized across videos depicting the same event schema, whereas the hippocampus maintained event-specific representations. 2023-03-08 2023-08-14 Not clear
Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior. 2023-03-04. PMID:36870422. the present study demonstrated for the first time that acute as well as subchronic (4 days) administration of the experimental ghs-r1a antagonist jmv2959 in usual intraperitoneal doses including 3 mg/kg, had no influence on memory functions tested in the morris water maze in rats as well as no significant effects on the molecular markers linked with memory processing in selected brain areas in rats, specifically on the β-actin, c-fos, two forms of the calcium/calmodulin-dependent protein kinase ii (camkii, p-camkii) and the camp-response element binding protein (creb, p-creb), within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum, and hippocampus (hipp). 2023-03-04 2023-08-14 rat
Jae Soon Kang, Ji Hyeong Baek, Mi Yeong Song, Naveed Ur Rehman, Hye Jin Chung, Dong Kun Lee, Dae Young Yoo, Hyun Joon Ki. Long-term exposure changes the environmentally relevant bis(2-ethylhexyl) phthalate to be a neuro-hazardous substance disrupting neural homeostasis in emotional and cognitive functions. Environmental pollution (Barking, Essex : 1987). 2023-03-04. PMID:36870594. long-term dehp ingestion induced collapse of glutamate (glu) and glutamine (gln) homeostasis as a result of disruption of the glu-gln cycle in the medial prefrontal cortex and hippocampus. 2023-03-04 2023-08-14 mouse
Emerson de Oliveira Ferreira, Jéssica Maria Pessoa Gomes, Kelly Rose Tavares Neves, Francisco Arnaldo Viana Lima, Glauce Socorro de Barros Viana, Geanne Matos de Andrad. Maternal treatment with aripiprazole prevents the development of a valproic acid-induced autism-like phenotype in juvenile male mice. Behavioural pharmacology. 2023-02-28. PMID:36853856. in the present study, we examined the effects of maternal treatment with apz (10 mg/kg) in juvenile mice prenatally exposed to vpa on neurodevelopmental behaviors, social interactions, communication, and working memory, as well as synaptophysin (syp), synaptosomal-associated protein, 25 kda (snap-25) and microtubule-associated protein 2 (map-2) expression in the medial prefrontal cortex (mpfc) and cell viability in the hippocampus. 2023-02-28 2023-08-14 mouse
Thays Brenner Santos, Juliana Carlota Kramer-Soares, Maria Gabriela Menezes Oliveir. Contextual fear conditioning with a time interval induces CREB phosphorylation in the dorsal hippocampus and amygdala nuclei that depend on prelimbic cortex activity. Hippocampus. 2023-02-27. PMID:36847108. for this, we observed in wistar rats the effect of pre-training pl inactivation by muscimol in creb (camp response element-binding protein) phosphorylation, which is essential for memory consolidation, in subdivisions of the medial prefrontal cortex (mpfc), hippocampus, and amygdala 3 h after the training in the contextual fear conditioning (cfc) or cfc with 5-s interval (cfc-5s), fear associations without or with an interval between the cs and us, respectively. 2023-02-27 2023-08-14 rat
Shi Yan, Chang Xu, Mengli Yang, Huiqiang Zhang, Ye Cheng, Zeping Xue, Zecong He, Tiantian Wang, Shangying Bai, Gang Wang, Jianping Wu, Zhiqian Tong, Xiang Ca. The expression of agmatinase manipulates the affective state of rats subjected to chronic restraint stress. Neuropharmacology. 2023-02-27. PMID:36849038. in this study, we observed that agmat expression increased in the ventral hippocampus rather than in the medial prefrontal cortex in the chronic restraint stress (crs) animal model of depression. 2023-02-27 2023-08-14 rat
Phillip M Muza, Daniel Bush, Marta Pérez-González, Ines Zouhair, Karen Cleverley, Miriam L Sopena, Rifdat Aoidi, Steven J West, Mark Good, Victor L J Tybulewicz, Matthew C Walker, Elizabeth M C Fisher, Pishan Chan. Cognitive impairments in a Down syndrome model with abnormal hippocampal and prefrontal dynamics and cytoarchitecture. iScience. vol 26. issue 2. 2023-02-23. PMID:36818290. in this study, we investigated neuronal dysfunction in the dp(10)2yey mouse and report spatial memory impairment and anxiety-like behavior alongside altered neural activity in the medial prefrontal cortex (mpfc) and hippocampus (hpc). 2023-02-23 2023-08-14 mouse
Shang Lin Tommy Lee, Brian Timmerman, Riley Pflomm, Nikita Roy, Mahathi Kumar, Etan J Marku. Sequential order spatial memory in male rats: Characteristics and impact of medial prefrontal cortex and hippocampus disruption. Neurobiology of learning and memory. 2023-02-23. PMID:36822465. sequential order spatial memory in male rats: characteristics and impact of medial prefrontal cortex and hippocampus disruption. 2023-02-23 2023-08-14 rat
Michael Murack, Kevin B Smith, Olivia H Traynor, Atiqa F Pirwani, Sarah K Gostlin, Taha Mohamed, Despina A Tata, Claude Messier, Nafissa Ismai. Environmental Enrichment Alters LPS-induced changes in BDNF and PSD-95 Expressions During Puberty. Brain research. 2023-02-21. PMID:36801452. male and female ee mice displayed greater bdnf and psd-95 expressions in the medial prefrontal cortex and hippocampus compared to socially housed and deprived housed mice. 2023-02-21 2023-08-14 mouse
Michael Murack, Kevin B Smith, Olivia H Traynor, Atiqa F Pirwani, Sarah K Gostlin, Taha Mohamed, Despina A Tata, Claude Messier, Nafissa Ismai. Environmental Enrichment Alters LPS-induced changes in BDNF and PSD-95 Expressions During Puberty. Brain research. 2023-02-21. PMID:36801452. interestingly, lps-treated mice housed in deprived conditions displayed unexpected increases in bdnf and psd-95 expressions throughout the medial prefrontal cortex and hippocampus. 2023-02-21 2023-08-14 mouse
Koral Goltseker, Patricia Garay, Katherine Bonefas, Shigeki Iwase, Segev Bara. Alcohol-specific transcriptional dynamics of memory reconsolidation and relapse. Translational psychiatry. vol 13. issue 1. 2023-02-15. PMID:36792579. using a mouse place-conditioning procedure, we show that alcohol-memory retrieval increases the mrna expression of immediate-early genes in the dorsal hippocampus and medial prefrontal cortex, and that alcohol seeking is abolished by post-retrieval non-specific inhibition of gene transcription, or by downregulating arc expression using antisense-oligodeoxynucleotides. 2023-02-15 2023-08-14 mouse