| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sam Audrain, Mary Pat McAndrew. Schemas provide a scaffold for neocortical integration of new memories over time. Nature communications. vol 13. issue 1. 2022-10-02. PMID:36184668. |
when a congruent schema was available, memory became coarser over time, aided by post-encoding coupling between the anterior hippocampus and medial prefrontal cortex (mpfc). |
2022-10-02 |
2023-08-14 |
Not clear |
| Isabel López-Taboada, Saúl Sal-Sarria, Guillermo Vallejo, Ana Coto-Montes, Nélida M Conejo, Héctor González-Pard. SEXUAL DIMORPHISM IN SPATIAL LEARNING AND BRAIN METABOLISM AFTER EXPOSURE TO A WESTERN DIET AND EARLY LIFE STRESS IN RATS. Physiology & behavior. 2022-10-01. PMID:36181786. |
for this purpose, spatial learning and memory and behavioural flexibility were evaluated in the morris water maze, and regional brain oxidative capacity and oxidative stress levels were measured in the hippocampus and medial prefrontal cortex. |
2022-10-01 |
2023-08-14 |
rat |
| Nathanael Shing, Matthew C Walker, Pishan Chan. The Role of Aberrant Neural Oscillations in the Hippocampal-Medial Prefrontal Cortex Circuit in Neurodevelopmental and Neurological Disorders. Neurobiology of learning and memory. 2022-09-29. PMID:36174886. |
the hippocampus (hpc) and medial prefrontal cortex (mpfc) have well-established roles in cognition, emotion, and sensory processing. |
2022-09-29 |
2023-08-14 |
Not clear |
| Veronika Samborska, James L Butler, Mark E Walton, Timothy E J Behrens, Thomas Aka. Complementary task representations in hippocampus and prefrontal cortex for generalizing the structure of problems. Nature neuroscience. 2022-09-28. PMID:36171429. |
neurons in medial prefrontal cortex (mpfc) maintained similar representations across problems despite their different sensorimotor correlates, whereas hippocampal (dca1) representations were more strongly influenced by the specifics of each problem. |
2022-09-28 |
2023-08-14 |
mouse |
| Ezio Carboni, Anna R Cart. BDNF Alterations in Brain Areas and the Neurocircuitry Involved in the Antidepressant Effects of Ketamine in Animal Models, Suggest the Existence of a Primary Circuit of Depression. Journal of integrative neuroscience. vol 21. issue 5. 2022-09-22. PMID:36137960. |
in this review we have examined the role of several brain areas: namely, the hippocampus, the medial prefrontal cortex (mpfc), the nucleus accumbens (nac), the lateral habenula (lhb), the amygdala and the bed nucleus of stria terminalis (bnst). |
2022-09-22 |
2023-08-14 |
Not clear |
| Daniel Ramirez-Gordillo, K Ulrich Bayer, Diego Restrep. Hippocampal-prefrontal theta coupling develops as mice become proficient in associative odorant discrimination learning. eNeuro. 2022-09-20. PMID:36127136. |
here we studied the interaction between infralimbic medial prefrontal cortex (mpfc) and hippocampal dorsal ca1 during associative odorant discrimination learning in the mouse. |
2022-09-20 |
2023-08-14 |
mouse |
| Bongjun Sur, Bombi Le. Luteolin reduces fear, anxiety, and depression in rats with post-traumatic stress disorder. Animal cells and systems. vol 26. issue 4. 2022-09-01. PMID:36046028. |
also, administration of lu restored the increased norepinephrine and decreased serotonin levels in the structures within the fear circuit, medial prefrontal cortex, and hippocampus. |
2022-09-01 |
2023-08-14 |
rat |
| Haley A Vecchiarelli, Maria Morena, Tiffany T Y Lee, Andrei S Nastase, Robert J Aukema, Kira D Leitl, J Megan Gray, Gavin N Petrie, Kristin J Tellez-Monnery, Matthew N Hil. Sex and stressor modality influence acute stress-induced dynamic changes in corticolimbic endocannabinoid levels in adult Sprague Dawley rats. Neurobiology of stress. vol 20. 2022-08-30. PMID:36039150. |
thirty minutes following stress onset, we excised the amygdala, hippocampus and medial prefrontal cortex, corticolimbic brain regions involved in the stress response, to measure endocannabinoid levels. |
2022-08-30 |
2023-08-14 |
rat |
| Laura Durieux, Karine Herbeaux, Christopher Borcuk, Cécile Hildenbrand, Virginie Andry, Yannick Goumon, Alexandra Barbelivien, Chantal Mathis, Demian Bataglia, Monique Majchrzak, Lucas Lecourtie. Functional brain-wide network mapping during acute stress exposure in rats: Interaction between the lateral habenula and cortical, amygdalar, hypothalamic and monoaminergic regions. The European journal of neuroscience. 2022-08-22. PMID:35993349. |
it has been known for decades that the main structures engaged during the stress response are the medial prefrontal cortex, the amygdala, the hippocampus, the hypothalamus, the monoaminergic systems (noradrenaline, dopamine, serotonin), and the periaqueductal gray. |
2022-08-22 |
2023-08-14 |
rat |
| Bongjun Sur, Bombi Le. Ginsenoside Rg3 modulates spatial memory and fear memory extinction by the HPA axis and BDNF-TrkB pathway in a rat post-traumatic stress disorder. Journal of natural medicines. 2022-08-18. PMID:35982366. |
rg3 administration improved fear memory and spatial memory might be involved in modulating the dysregulation of the hypothalamic-pituitary-adrenal (hpa) axis and monoamine imbalance in the medial prefrontal cortex and hippocampus. |
2022-08-18 |
2023-08-14 |
rat |
| Jie Chen, Sumei Liu, Xueqin Wang, Jufang Huang, Jade Phillips, Daqing Ma, Wen Ouyang, Jianbin Ton. HDAC6 Inhibition Alleviates Anesthesia and Surgery-Induced Less Medial Prefrontal-Dorsal Hippocampus Connectivity and Cognitive Impairment in Aged Rats. Molecular neurobiology. 2022-07-26. PMID:35882756. |
hdac6 shrna was injected into medial prefrontal cortex and hippocampus bilaterally before hepatectomy or an hdac6 activity inhibitor tubastatin a was administered systemically after hepatectomy. |
2022-07-26 |
2023-08-14 |
rat |
| Jie Chen, Sumei Liu, Xueqin Wang, Jufang Huang, Jade Phillips, Daqing Ma, Wen Ouyang, Jianbin Ton. HDAC6 Inhibition Alleviates Anesthesia and Surgery-Induced Less Medial Prefrontal-Dorsal Hippocampus Connectivity and Cognitive Impairment in Aged Rats. Molecular neurobiology. 2022-07-26. PMID:35882756. |
neuroinflammation and hdac6 down-target ac-tubulin in medial prefrontal cortex and hippocampus were detected. |
2022-07-26 |
2023-08-14 |
rat |
| Xue Gu, Yan-Jiao Wu, Zichen Zhang, Jia-Jie Zhu, Xin-Rong Wu, Qi Wang, Xin Yi, Ze-Jie Lin, Zhi-Han Jiao, Miao Xu, Qin Jiang, Ying Li, Nan-Jie Xu, Michael X Zhu, Lu-Yang Wang, Fan Jiang, Tian-Le Xu, Wei-Guang L. Dynamic tripartite construct of interregional engram circuits underlies forgetting of extinction memory. Molecular psychiatry. 2022-07-08. PMID:35804093. |
using an activity-dependent neuronal labeling strategy, we demonstrate that engram neurons for fear extinction memory are dynamically positioned in the medial prefrontal cortex (mpfc), basolateral amygdala (bla), and ventral hippocampus (vhpc), which constitute an engram construct in the term of directional engram synaptic connectivity from the bla or vhpc to mpfc, but not that in the opposite direction, for retrieval of extinction memory. |
2022-07-08 |
2023-08-14 |
Not clear |
| Jozef Mizera, Grzegorz Kazek, Bartosz Pomierny, Beata Bystrowska, Ewa Niedzielska-Andres, Lucyna Pomierny-Chamiol. Maternal High-Fat diet During Pregnancy and Lactation Disrupts NMDA Receptor Expression and Spatial Memory in the Offspring. Molecular neurobiology. 2022-06-30. PMID:35773600. |
sex-dependent changes in glutamate levels were identified in extracellular fluid obtained from the medial prefrontal cortex and the hippocampus of the offspring. |
2022-06-30 |
2023-08-14 |
human |
| Scott A Kinlein, Naomi K Wallace, Marina I Savenkova, Ilia N Karatsoreo. Chronic hypothalamic-pituitary-adrenal axis disruption alters glutamate homeostasis and neural responses to stress in male C57Bl6/N mice. Neurobiology of stress. vol 19. 2022-06-20. PMID:35720261. |
using laser microdissection and transcriptomic analyses, we show that chronic disruption of the hpa axis alters the expression of genes related to glutamate signaling in the medial prefrontal cortex (mpfc), hippocampus, and amygdala. |
2022-06-20 |
2023-08-14 |
mouse |
| Bongjun Sur, Bombi Le. Myricetin Inhibited Fear and Anxiety-Like Behaviors by HPA Axis Regulation and Activation of the BDNF-ERK Signaling Pathway in Posttraumatic Stress Disorder Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-06-20. PMID:35722162. |
also, administration of myr restored decreased serotonin and increased norepinephrine in the fear circuit regions, medial prefrontal cortex, and hippocampus. |
2022-06-20 |
2023-08-14 |
rat |
| Cai-N Cheng, Shaw-Jye Wu, Andrew Chih Wei Huan. Environmental Enrichment Components Required to Reduce Methamphetamine-Induced Behavioral Sensitization in Mice: Examination of Behaviors and Neural Substrates. Journal of clinical medicine. vol 11. issue 11. 2022-06-10. PMID:35683439. |
the c-fos expression analysis showed that the medial prefrontal cortex (i.e., cingulate cortex 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), nucleus accumbens (nac), basolateral amygdala (bla), ventral tegmental area (vta), caudate-putamen (cpu), and hippocampus (i.e., ca1, ca3, and dentate gyrus (dg)) contributed to mamph-induced behavioral sensitization. |
2022-06-10 |
2023-08-14 |
mouse |
| Jozef Mizera, Bartosz Pomierny, Anna Sadakierska-Chudy, Beata Bystrowska, Lucyna Pomierny-Chamiol. Disruption of Glutamate Homeostasis in the Brain of Rat Offspring Induced by Prenatal and Early Postnatal Exposure to Maternal High-Sugar Diet. Nutrients. vol 14. issue 11. 2022-06-10. PMID:35683984. |
glutamate concentration was assessed in extracellular fluid samples collected from the medial prefrontal cortex and hippocampus of male and female offspring. |
2022-06-10 |
2023-08-14 |
rat |
| Bo Zhou, Xuejiao Dou, Wei Wang, Hongxiang Yao, Feng Feng, Pan Wang, Zhengyi Yang, Ningyu An, Bing Liu, Xi Zhang, Yong Li. Structural and functional connectivity abnormalities of the default mode network in patients with Alzheimer's disease and mild cognitive impairment within two independent datasets. Methods (San Diego, Calif.). 2022-06-07. PMID:35671900. |
disrupted sc and fc were found among dmn components (e.g., the posterior cingulate cortex (pcc), medial prefrontal cortex (mpfc), and hippocampus) in patients in the amci and ad groups in the discovery dataset; most of the disrupted connections were also identified in the replication dataset. |
2022-06-07 |
2023-08-14 |
human |
| Chen-Cheng Lin, Pao-Yun Cheng, Michael Hsiao, Yia-Ping Li. Effects of RU486 in Treatment of Traumatic Stress-Induced Glucocorticoid Dysregulation and Fear-Related Abnormalities: Early versus Late Intervention. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628305. |
neurochemically, the expressions of gr, fk506-binding proteins 4 and 5 (fkbp4 and fkbp5), and early growth response-1 (egr-1) were assessed in the hippocampus, medial prefrontal cortex (mpfc), amygdala, and hypothalamus, together with the level of plasma corticosterone. |
2022-05-28 |
2023-08-13 |
rat |