| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Guo, Xi Xiao, Yu-Tao Tian, Jia-Jia Yan. [The role and mechanism of SIRT1 gene in depression]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 5. 2021-10-29. PMID:34708240. |
therefore, this review mainly summarizes the relevant research progress on the role and mechanism of sirt1 gene in the hippocampus, prefrontal cortex, amygdala, hypothalamic suprachiasmatic nucleus, and nucleus accumbens in depression, in order to provide new ideas for exploring the mechanism and prevention of depression. |
2021-10-29 |
2023-08-13 |
Not clear |
| Anne T Park, Ursula A Tooley, Julia A Leonard, Austin L Boroshok, Cassidy L McDermott, M Dylan Tisdall, Allyson P Macke. Early childhood stress is associated with blunted development of ventral tegmental area functional connectivity. Developmental cognitive neuroscience. vol 47. 2021-10-13. PMID:33395612. |
work in animals has shown that early life stress has a profound impact on the ventral tegmental area (vta), which provides dopamine to regions including nucleus accumbens (nacc), anterior hippocampus, and medial prefrontal cortex (mpfc), with cascading effects over the course of development. |
2021-10-13 |
2023-08-13 |
Not clear |
| Elaheh Soleimanpour, Jorge R Bergado Acosta, Peter Landgraf, Dana Mayer, Evelyn Dankert, Daniela C Dieterich, Markus Fend. Regulation of CREB Phosphorylation in Nucleus Accumbens after Relief Conditioning. Cells. vol 10. issue 2. 2021-10-12. PMID:33530478. |
forty-five minutes or 6 h after conditioning, samples of five different brain regions, namely the prefrontal cortex, nucleus accumbens (nac), dorsal striatum, dorsal hippocampus, and amygdala, were collected. |
2021-10-12 |
2023-08-13 |
rat |
| Wenwen Gao, Guangfei Li, Xiaowei Han, Zeyu Song, Shuai Zhao, Feiyi Sun, Hong Ma, Ailing Cui, Yige Wang, Xiuxiu Liu, Yue Chen, Lu Zhang, Guolin Ma, Xiaoying Tan. Regional brain network and behavioral alterations in EGR3 gene transfected rat model of schizophrenia. Brain imaging and behavior. vol 15. issue 5. 2021-10-12. PMID:33723811. |
besides, the regional architectures in the olfactory bulb, nucleus accumbens were lower in group t than group h, while the hippocampus showed increased regional architecture in group t compared to group h (p < 0.05). schizophrenia induced several regional alterations in the cerebrum while risperidone can reverse part of these alterations. |
2021-10-12 |
2023-08-13 |
rat |
| Marco Pignatelli, Hugo A Tejeda, David J Barker, Leonardo Bontempi, Jocelyn Wu, Alejandra Lopez, Sissi Palma Ribeiro, Federica Lucantonio, Eric M Parise, Angélica Torres-Berrio, Yocasta Alvarez-Bagnarol, Rosa A M Marino, Zhao-Lin Cai, Mingshan Xue, Marisela Morales, Carol A Tamminga, Eric J Nestler, Antonello Bonc. Cooperative synaptic and intrinsic plasticity in a disynaptic limbic circuit drive stress-induced anhedonia and passive coping in mice. Molecular psychiatry. vol 26. issue 6. 2021-10-11. PMID:32161361. |
here, we show in a mouse model for stress-induced anhedonia and passive coping that these phenomena are associated with increased synaptic strength of ventral hippocampus (vh) excitatory synapses onto d1 medium spiny neurons (d1-msns) in the nucleus accumbens medial shell (nacmsh), and with lateral hypothalamus (lh)-projecting d1-msn hyperexcitability mediated by decreased inwardly rectifying potassium channel (irk) function. |
2021-10-11 |
2023-08-13 |
mouse |
| Limeng Huang, Yiwen Chen, Sen Jin, Li Lin, Shumin Duan, Ke Si, Wei Gong, J Julius Zh. Organizational principles of amygdalar input-output neuronal circuits. Molecular psychiatry. 2021-10-06. PMID:34400771. |
using a simplified cell-type- and projection-specific retrograde transsynaptic tracing technique, we scrutinized brain-wide afferent inputs of four major output neuronal groups in the amygdalar basolateral complex (bla) that project to the bed nucleus of the stria terminals (bnst), ventral hippocampus (vhpc), medial prefrontal cortex (mpfc) and nucleus accumbens (nac), respectively. |
2021-10-06 |
2023-08-13 |
Not clear |
| Leonardo A Guercio, Mathieu E Wimmer, Heath D Schmidt, Sarah E Swinford-Jackson, R Christopher Pierce, Fair M Vassole. Deep brain stimulation of the infralimbic cortex attenuates cocaine priming-induced reinstatement of drug seeking. Brain research. vol 1746. 2021-10-01. PMID:32652146. |
the present study investigated the effects of dbs in brain regions that send major glutamatergic projections to the nucleus accumbens including the basolateral amygdala (bla) and ventral hippocampus (vhipp) as well as subregions of the medial prefrontal cortex (mpfc) including the anterior cingulate, infralimbic and prelimbic cortices. |
2021-10-01 |
2023-08-13 |
rat |
| Hajime Miyanishi, Atsumi Nitt. A Role of BDNF in the Depression Pathogenesis and a Potential Target as Antidepressant: The Modulator of Stress Sensitivity "Shati/Nat8l-BDNF System" in the Dorsal Striatum. Pharmaceuticals (Basel, Switzerland). vol 14. issue 9. 2021-10-01. PMID:34577589. |
we reviewed a novel finding of bdnf function in the dorsal striatum, which induces vulnerability to social stress, in addition to recent research progress regarding the brain regional functions of bdnf, including the prefrontal cortex, hippocampus, and nucleus accumbens. |
2021-10-01 |
2023-08-13 |
Not clear |
| Yann Chye, Scott Mackey, Boris A Gutman, Christopher R K Ching, Albert Batalla, Sara Blaine, Samantha Brooks, Elisabeth C Caparelli, Janna Cousijn, Alain Dagher, John J Foxe, Anna E Goudriaan, Robert Hester, Kent Hutchison, Neda Jahanshad, Anne M Kaag, Ozlem Korucuoglu, Chiang-Shan R Li, Edythe D London, Valentina Lorenzetti, Maartje Luijten, Rocio Martin-Santos, Shashwath A Meda, Reza Momenan, Angelica Morales, Catherine Orr, Martin P Paulus, Godfrey Pearlson, Liesbeth Reneman, Lianne Schmaal, Rajita Sinha, Nadia Solowij, Dan J Stein, Elliot A Stein, Deborah Tang, Anne Uhlmann, Ruth van Holst, Dick J Veltman, Antonio Verdejo-Garcia, Reinout W Wiers, Murat Yücel, Paul M Thompson, Patricia Conrod, Hugh Garava. Subcortical surface morphometry in substance dependence: An ENIGMA addiction working group study. Addiction biology. vol 25. issue 6. 2021-09-28. PMID:31746534. |
meanwhile, nicotine use was associated with greater rd and jd relative to nonsmokers in multiple regions, with the strongest effects in the bilateral hippocampus and right nucleus accumbens. |
2021-09-28 |
2023-08-13 |
Not clear |
| Eric M Parise, Lyonna F Parise, Omar K Sial, Astrid M Cardona-Acosta, Trevonn M Gyles, Barbara Juarez, Dipesh Chaudhury, Ming-Hu Han, Eric J Nestler, Carlos A Bolaños-Guzmá. The Resilient Phenotype Induced by Prophylactic Ketamine Exposure During Adolescence Is Mediated by the Ventral Tegmental Area-Nucleus Accumbens Pathway. Biological psychiatry. vol 90. issue 7. 2021-09-27. PMID:34247781. |
recent evidence showed that ket reverses stress-induced (i.e., depressive-like) deficits within major mesocorticolimbic regions, such as the prefrontal cortex, nucleus accumbens (nac), and hippocampus, in adult rodents. |
2021-09-27 |
2023-08-13 |
Not clear |
| Susanne Nikolaus, Markus Beu, Hans-Jörg Wittsack, Anja Müller-Lutz, Christina Antke, Hubertus Hautzel, Yuriko Mori, Eduards Mamlins, Gerald Antoch, Hans-Wilhelm Mülle. GABAergic and glutamatergic effects on nigrostriatal and mesolimbic dopamine release in the rat. Reviews in the neurosciences. vol 31. issue 6. 2021-09-24. PMID:32619197. |
in these studies, [123i]iodobenzamide binding to the d2/3r was mesured in nucleus accumbens (nac), caudateputamen (cp), substantia nigra/ventral tegmental area (sn/vta), frontal (fc), motor (mc) and parietal cortex (pc) as well as anterior (ahipp) and posterior hippocampus (phipp) with small animal spect in baseline and after injection of either the gabaar agonist muscimol (1 mg/kg), the gabaar antagonist bicuculline (1 mg/kg), the nmdar agonist d-cycloserine (20 mg/kg) or the nmdar antagonist amantadine (40 mg/kg). |
2021-09-24 |
2023-08-13 |
rat |
| Talia Sabran-Cohen, Uri Bright, Tomer Mizrachi Zer-Aviv, Irit Akira. Rapamycin prevents the long-term impairing effects of adolescence Δ-9-tetrahydrocannabinol on memory and plasticity in male rats. The European journal of neuroscience. vol 54. issue 6. 2021-09-24. PMID:34405459. |
thirty days after the last injection, rats were tested for short-term and working memory, anxiety-like behaviour, and plasticity in the pathways projecting from the ventral subiculum (vsub) of the hippocampus to the prefrontal cortex (pfc) and nucleus accumbens (nac). |
2021-09-24 |
2023-08-13 |
rat |
| Weikang Cai, Xuemei Zhang, Thiago M Batista, Rubén García-Martín, Samir Softic, Guoxiao Wang, Alfred K Ramirez, Masahiro Konishi, Brian T O'Neill, Jong Hun Kim, Jason K Kim, C Ronald Kah. Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens. Diabetes. vol 70. issue 8. 2021-09-21. PMID:34031123. |
peripheral insulin regulates a broad network of gene expression in hypothalamus, hippocampus, and nucleus accumbens. |
2021-09-21 |
2023-08-13 |
mouse |
| Weikang Cai, Xuemei Zhang, Thiago M Batista, Rubén García-Martín, Samir Softic, Guoxiao Wang, Alfred K Ramirez, Masahiro Konishi, Brian T O'Neill, Jong Hun Kim, Jason K Kim, C Ronald Kah. Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens. Diabetes. vol 70. issue 8. 2021-09-21. PMID:34031123. |
insulin regulates distinct pathways in the hypothalamus (htm), hippocampus, and nucleus accumbens. |
2021-09-21 |
2023-08-13 |
mouse |
| Qing Shang, Min Liang, Jing Xiao, Baoyao Gao, Hongyan Qian, Jing Wang, Gang Chen, Jie Fang, Tao Li, Xinshe Li. LB100 attenuates methamphetamine-induced behavioral sensitization by inhibiting the Raf1-ERK 1/2 cascade in the caudate putamen. Neuroreport. vol 32. issue 12. 2021-09-20. PMID:34102646. |
in addition, western blot was used to examine the levels of p-raf1 (ser 259) and p-erk 1/2 (thr 202/tyr 204) in the cpu, hippocampus (hip) and nucleus accumbens (nac). |
2021-09-20 |
2023-08-13 |
mouse |
| Adam Hamed, Miron Bartosz Kurs. Social deprivation substantially changes multi-structural neurotransmitter signature of social interaction: Glutamate concentration in amygdala and VTA as a key factor in social encounter-induced 50-kHz ultrasonic vocalization. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 37. 2021-08-26. PMID:32651127. |
social encounter-induced 50-khz usvs were bound up with changes in glutamate in amygdala and vta, glycine in the amygdala, vta, hippocampus, nucleus accumbens and cpu, and dopamine metabolites in vta and cpu. |
2021-08-26 |
2023-08-13 |
rat |
| Ryan E Tyler, Benjamin Z S Weinberg, Dennis F Lovelock, Laura C Ornelas, Joyce Beshee. Exposure to the predator odor TMT induces early and late differential gene expression related to stress and excitatory synaptic function throughout the brain in male rats. Genes, brain, and behavior. vol 19. issue 8. 2021-08-17. PMID:32666635. |
two days after tmt, grm3 was downregulated in the prelimbic cortex and dorsal hippocampus, but upregulated in the nucleus accumbens. |
2021-08-17 |
2023-08-13 |
rat |
| Ryan E Tyler, Benjamin Z S Weinberg, Dennis F Lovelock, Laura C Ornelas, Joyce Beshee. Exposure to the predator odor TMT induces early and late differential gene expression related to stress and excitatory synaptic function throughout the brain in male rats. Genes, brain, and behavior. vol 19. issue 8. 2021-08-17. PMID:32666635. |
finally, another experiment 4 weeks after tmt exposure showed several differentially expressed genes known to mediate excitatory tripartite synaptic function in the prelimbic cortex (grm5, dlg4 and slc1a3 upregulated), infralimbic cortex (grm2 downregulated, homer1 upregulated), nucleus accumbens (grm7 and slc1a3 downregulated), dorsal hippocampus (fkbp5 and nr3c2 upregulated, shank3 downregulated) and ventral hippocampus (cnr1, grm7, grm5, shank3 and homer1 downregulated). |
2021-08-17 |
2023-08-13 |
rat |
| H Z Rosa, R C S Barcelos, H J Segat, Kr Roversi, V T Dias, L H Milanesi, M E Burge. Physical exercise modifies behavioral and molecular parameters related to opioid addiction regardless of training time. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 32. 2021-08-10. PMID:31899030. |
on the last exercising week, one-half of the animals from sed and all animals from s-, m- and l-exe were concomitantly exposed to morphine-conditioned place preference (cpp) paradigm and y-maze task for behavioral assessments followed by molecular assays in both nucleus accumbens (nac) and hippocampus. |
2021-08-10 |
2023-08-13 |
rat |
| Fabiola Natividad Carvajal-Flores, Alfonso Díaz, Gabriel D Flores-Gómez, Fidel de la Cruz, Gonzalo Flore. Phenylbutyrate ameliorates prefrontal cortex, hippocampus, and nucleus accumbens neural atrophy as well as synaptophysin and GFAP stress in aging mice. Synapse (New York, N.Y.). vol 74. issue 11. 2021-08-10. PMID:32531811. |
phenylbutyrate ameliorates prefrontal cortex, hippocampus, and nucleus accumbens neural atrophy as well as synaptophysin and gfap stress in aging mice. |
2021-08-10 |
2023-08-13 |
mouse |