| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Grace H Curtis, Robyn E Reeve, Erica J Cresp. Leptin signaling promotes blood vessel formation in the Xenopus tail during the embryo-larval transition. Developmental biology. 2024-05-05. PMID:38705558. |
reduced leptin signaling lowered mrna expression of cenpk, gpx1, and mmp9, markers for cell proliferation, antioxidation, and extracellular matrix remodeling/cell migration, respectively, in the developing tail, providing insight into three possible mechanisms underlying leptin's promotion of angiogenesis. |
2024-05-05 |
2024-05-08 |
xenopus_laevis |
| Jie Zhou, Chau Q Le, Yun Zhang, James A Well. A general approach for selection of epitope-directed binders to proteins. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 19. 2024-04-29. PMID:38683990. |
we generated antibodies that recognize the junction between the pro- and catalytic domains for three different matrix metalloproteases (mmps), mmp1, mmp3, and mmp9, that selectively block activation of each of these enzymes and impair cell migration. |
2024-04-29 |
2024-05-03 |
Not clear |
| Huixian Huang, Jia Huang, Wensi Lu, Yanjun Huang, Ran Luo, Luqman Bathalian, Ming Chen, Xuemin Wan. A Four-Week High-Fat Diet Induces Anxiolytic-like Behaviors through Mature BDNF in the mPFC of Mice. Brain sciences. vol 14. issue 4. 2024-04-27. PMID:38672038. |
furthermore, mrna levels of the n6-methyladenosine (m6a) demethylase, fat mass and obesity-associated protein (fto), and the hydrolase matrix metalloproteinase-9 (mmp9), also increased in the mpfc. |
2024-04-27 |
2024-04-29 |
mouse |
| Bingli Liu, Liping Su, Sze Jie Loo, Yu Gao, Ester Khin, Xiaocen Kong, Rinkoo Dalan, Xiaofei Su, Kok-Onn Lee, Jianhua Ma, Lei Y. Matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes. Frontiers in endocrinology. vol 15. 2024-04-25. PMID:38660518. |
to determine the roles of matrix metallopeptidase-9 (mmp9) on human coronary artery smooth muscle cells (hcasmcs) |
2024-04-25 |
2024-04-28 |
human |
| Marta Halasa, Ahmed Uosef, Henry V Ubelaker, Arijita Subuddhi, Krupa R Mysore, Jacek Z Kubiak, Rafik M Ghobrial, Jarek Wosik, Malgorzata Klo. Gadolinium retention effect on macrophages - a potential cause of MRI contrast agent Dotarem toxicity. Cell and tissue research. 2024-04-16. PMID:38625373. |
gadolinium retention for 7 days decreased macrophage adhesion and motility and dysregulated the expression of adhesion and fibrotic pathway-related proteins such as notch1 and its ligand jagged1, adhesion/migration-related proteins pak1 and shp1, immune response-related transcription factors smad3 and tcf19, and chemokines cxcl10 and cxcl13, and dysregulated the mrna expression of fibrosis-related genes involved in extracellular matrix (ecm) synthesis, such as col6a1, fibronectin, mmp9, and mmp12. |
2024-04-16 |
2024-04-18 |
Not clear |
| Yulong Zhang, Chenxi Gao, Juncong Luo, Arsalan Khan, Mounir M Salem-Bekhit, Mohamed M Salem, Zeng Qi, Bo Jian. Deciphering the role of wound healing genes in skin cutaneous melanoma: Insights into expression, methylation, mutations, and therapeutic implications. International wound journal. vol 21. issue 4. 2024-04-09. PMID:38591163. |
in this comprehensive study, we investigated the intricate roles of two important wound healing genes in skcm, including matrix metalloproteinase-2 (mmp2) and matrix metalloproteinase-9 (mmp9). |
2024-04-09 |
2024-04-11 |
Not clear |
| Huirong Li, Liang Ding, Jian Ding, Fudan Huan. The Influence of CD40/CD40L, MMP2/MMP9 on Uterine Artery Blood Flow and Their Expression in Recurrent Miscarriage. Alternative therapies in health and medicine. 2024-04-06. PMID:38581334. |
this study aims to investigate the expression levels of soluble cd40l (scd40l), matrix metalloproteinase 2 (mmp2), and matrix metalloproteinase 9 (mmp9) in the serum of patients experiencing recurrent abortion and their impact on uterine artery blood flow. |
2024-04-06 |
2024-04-10 |
Not clear |
| Kunlun Li, Dandan Li, Barbod Hafez, Mounir M Salem Bekhit, Yousef A Bin Jardan, Fars Kaed Alanazi, Ehab I Taha, Sayed H Auda, Faiqah Ramzan, Muhammad Jami. Identifying and validating MMP family members (MMP2, MMP9, MMP12, and MMP16) as therapeutic targets and biomarkers in kidney renal clear cell carcinoma (KIRC). Oncology research. vol 32. issue 4. 2024-04-01. PMID:38560573. |
by performing string and cytohubba analyses of the 24 mmp gene family members, mmp2 (matrix metallopeptidase 2), mmp9 (matrix metallopeptidase 9), mmp12 (matrix metallopeptidase 12), and mmp16 (matrix metallopeptidase 16) genes were denoted as hub genes having highest degree scores. |
2024-04-01 |
2024-04-04 |
Not clear |
| Wen Guo, Mangmang Xu, Xindi Song, Yajun Cheng, Yilun Deng, Ming Li. Association of Serum Macrophage Migration Inhibitory Factor with 3-Month Poor Outcome and Malignant Cerebral Edema in Patients with Large Hemispheric Infarction. Neurocritical care. 2024-04-01. PMID:38561586. |
we aimed to investigate the associations of macrophage migration inhibitory factor (mif), toll-like receptors 2 and 4 (tlr2/4), and matrix metalloproteinase 9 (mmp9) with 3-month poor outcome, death, and malignant cerebral edema (mce) in patients with large hemispheric infarction (lhi). |
2024-04-01 |
2024-04-04 |
Not clear |
| Linping Wang, Luyi Chen, Daniel Schlenk, Feixue Li, Jing Li. Parabens promotes invasive properties of multiple human cells: A potential cancer-associated adverse outcome pathway. The Science of the total environment. 2024-03-28. PMID:38547973. |
mp and pp up-regulated the expression levels and enzymatic activities of matrix metalloproteinase 2 and 9 (mmp2 and mmp9), as well as altered the expression of the tissue inhibitors of metalloproteinase 1 and 2 (timp1 and timp2) in four cell lines, suggesting mmps/timps as potential key events (kes) for paraben-induced cell invasion. |
2024-03-28 |
2024-03-31 |
human |
| Yan Yang, Yue Cheng, Yanfei Mu, Xianjun Tang, Xiaosong M. Lentinan inhibits cell invasion via M2 polarization of tumor-associated macrophages and Wnt/β-catenin signaling in non-small cell lung cancer. Chemical biology & drug design. vol 103. issue 3. 2024-03-27. PMID:38538070. |
matrix metallopeptidase 9 (mmp9) levels were measured through immunofluorescence staining. |
2024-03-27 |
2024-03-30 |
Not clear |
| Bogdan Stelian Mastalier Manolescu, Angela Mădălina Lazar, George Sorin Ţiplica, Sabina Andrada Zurac, Adrian Reboşapcă, Bogdan Andreescu, Cristiana Gabriela Pop. MMP1, MMP9, MMP11 and MMP13 in melanoma and its metastasis - key points in understanding the mechanisms and celerity of tumor dissemination. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 65. issue 1. 2024-03-26. PMID:38527983. |
matrix metalloproteinase (mmp)1, mmp9, mmp11, and mmp13 are overexpressed in malignant melanoma (mm), being associated with tumor invasive phase, metastases, and more aggressive neoplastic phenotypes. |
2024-03-26 |
2024-03-28 |
Not clear |
| Haotian Zheng, Linxin Yang, Huashang Huang, Yazhou Lin, Lin Che. Morroniside improves AngII-induced cardiac fibroblast proliferation, migration, and extracellular matrix deposition by blocking p38/JNK signaling pathway through the downregulation of KLF5. Naunyn-Schmiedeberg's archives of pharmacology. 2024-03-13. PMID:38472369. |
in this study, it was found that mor treatment inhibited angii-induced hyperproliferation, migration, and fibrosis of hcf cells, accompanied with decreased activities of matrix metalloproteinase 2 (mmp2), matrix metalloproteinase 9 (mmp9), connective tissue growth factor (ctgf), fibronectin, and α-sma, which were all reversed by klf5 overexpression. |
2024-03-13 |
2024-03-15 |
human |
| Anthony Altieri, Courtney Lynn Marshall, Padmanie Ramotar, Dylan Lloyd, Mahadevappa Hemshekhar, Victor Spicer, Anne M van der Does, Neeloffer Mookherje. Human host defence peptide LL-37 suppresses TNFα-mediated matrix metalloproteinases MMP9 and MMP13, in human bronchial epithelial cells. Journal of innate immunity. 2024-03-12. PMID:38471488. |
human host defence peptide ll-37 suppresses tnfα-mediated matrix metalloproteinases mmp9 and mmp13, in human bronchial epithelial cells. |
2024-03-12 |
2024-03-15 |
human |
| Daniel Jussen, Syamend Saeed, Tatjana Jablonski, Harald Krenzlin, Kristin Lucia, Tobias Kraemer, Oliver Kempski, Marcus Czabanka, Florian Ringel, Beat Alessandr. Influence of Blood Components on Neuroinflammation, Blood-Brain Barrier Breakdown, and Functional Damage After Acute Subdural Hematoma in Rats. Neurotrauma reports. vol 5. issue 1. 2024-03-11. PMID:38463418. |
integrity of the bbb was evaluated with albumin and matrix metalloproteinase 9 (mmp9) staining. |
2024-03-11 |
2024-03-14 |
rat |
| Xiaolin Chen, Ningyuan Wang, Chenyang Jing, Jianghan Li, Xuanhao Liu, Yuquan Yang, Tianhuan Song, Hao Ji. The TGF-β/MMP9/RAGE axis induces sRAGE secretion by neutrophils and promotes oral carcinogenesis. Biochemistry and biophysics reports. vol 38. 2024-03-11. PMID:38463640. |
tgf-β was found to induce the expression of rage and matrix metalloproteinase 9 (mmp9) in neutrophils. |
2024-03-11 |
2024-03-14 |
mouse |
| Suvendu Nandi, Soumyadeep Bhaduri, Debraj Das, Priya Ghosh, Mahitosh Mandal, Pralay Mitr. Deciphering the Lexicon of Protein Targets: A Review on Multifaceted Drug Discovery in the Era of Artificial Intelligence. Molecular pharmaceutics. 2024-03-11. PMID:38466810. |
we have also demonstrated the pathological conditions of heat shock protein 27 (hsp27) and matrix metallopoproteinases (mmp2 and mmp9) and designed inhibitors of these proteins using the drug discovery paradigm in a case study on the discovery of drug molecules for cancer treatment. |
2024-03-11 |
2024-03-14 |
Not clear |
| Ajwan Z Albalawi, Areej S Alatawi, Shekha M Al-Atwi, Lama S Alhwyty, Kadi M Alharbi, Shahad A Alshehri, Wasayf A Almarwani, Khulud K Aljohani, Hanan M Hassan, Mohammed M H Al-Gayya. Echinacoside ameliorates hepatic fibrosis and tumor invasion in rats with thioacetamide-induced hepatocellular carcinoma. Biomolecules & biomedicine. 2024-03-10. PMID:38461536. |
the hepatic expression of mrna and protein levels of tgf-β1, β-catenin, smad4, matrix metalloproteinase-9 (mmp9), phosphoinositide 3-kinases (pi3k), mammalian target of rapamycin (mtor), connective tissue growth factor 2 (ccn2), e-cadherin, platelets derived growth factor (pdgf)-b and fascin were also analyzed. |
2024-03-10 |
2024-03-14 |
rat |
| Sepehr Zamani, Majid Salehi, Arian Ehterami, Mh Busra Fauzi, Ghasem Abbaszadeh-Goudarz. Assessing the efficacy of curcumin-loaded alginate hydrogel on skin wound healing: A gene expression analysis. Journal of biomaterials applications. 2024-03-07. PMID:38453252. |
furthermore, the treated group exhibited down-regulation of mmp9 gene expression, indicating a reduction in matrix degradation and inflammation. |
2024-03-07 |
2024-03-10 |
Not clear |
| Jiali Li, Yan Wu, Qi Yuan, Luxin Li, Wenqi Qin, Jia Jia, Kaiyuan Chen, Dan Wu, Xiaohuan Yua. Gelatin Microspheres Based on H8-Loaded Macrophage Membrane Vesicles to Promote Wound Healing in Diabetic Mice. ACS biomaterials science & engineering. 2024-03-07. PMID:38450619. |
the high expression of matrix metalloproteinase 9 (mmp9) and a high inflammatory response are indicative of poor diabetic wound healing. |
2024-03-07 |
2024-03-09 |
mouse |